DD208233A5 - Pyridinfreies karl-fischer reagenz und verfahren zur bestimmung von wasser mit hilfe dieses reagenzes - Google Patents

Pyridinfreies karl-fischer reagenz und verfahren zur bestimmung von wasser mit hilfe dieses reagenzes Download PDF

Info

Publication number: DD208233A5
Authority: DD; German Democratic Republic
Prior art keywords: pyridine; reagent; solvent; free; water
Prior art date: 1980-12-20

Application number

DD81235899A

Other languages

German (de)

English (en)

Inventor

Wolfgang Fischer

Karl-Dieter Krenn

Original Assignee

Merck Patent Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1980-12-20

Filing date

1981-12-17

Publication date

1984-03-28

1981-12-17 Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh

1984-03-28 Publication of DD208233A5 publication Critical patent/DD208233A5/de

Links

XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 title claims abstract description 24
239000003153 chemical reaction reagent Substances 0.000 title claims abstract description 15
238000000034 method Methods 0.000 title claims abstract description 14
239000002904 solvent Substances 0.000 claims abstract description 43
JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical group C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 claims abstract description 34
RAHZWNYVWXNFOC-UHFFFAOYSA-N Sulphur dioxide Chemical group O=S=O RAHZWNYVWXNFOC-UHFFFAOYSA-N 0.000 claims abstract description 26
QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 claims abstract description 20
XNWFRZJHXBZDAG-UHFFFAOYSA-N 2-METHOXYETHANOL Chemical compound COCCO XNWFRZJHXBZDAG-UHFFFAOYSA-N 0.000 claims abstract description 17
UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Chemical group COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 claims abstract description 17
ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 claims abstract description 11
229910052740 iodine Inorganic materials 0.000 claims abstract description 11
239000011630 iodine Substances 0.000 claims abstract description 11
229910021529 ammonia Inorganic materials 0.000 claims abstract description 10
WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical group OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 claims abstract description 7
238000006467 substitution reaction Methods 0.000 claims abstract description 6
OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 30
238000004448 titration Methods 0.000 description 10
239000000126 substance Substances 0.000 description 8
LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 7
239000004299 sodium benzoate Substances 0.000 description 5
235000010234 sodium benzoate Nutrition 0.000 description 5
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 4
VMHLLURERBWHNL-UHFFFAOYSA-M Sodium acetate Chemical compound [Na+].CC([O-])=O VMHLLURERBWHNL-UHFFFAOYSA-M 0.000 description 4
150000001298 alcohols Chemical class 0.000 description 4
230000007717 exclusion Effects 0.000 description 4
230000010287 polarization Effects 0.000 description 4
239000001632 sodium acetate Substances 0.000 description 4
235000017281 sodium acetate Nutrition 0.000 description 4
WXMKPNITSTVMEF-UHFFFAOYSA-M sodium benzoate Chemical compound [Na+].[O-]C(=O)C1=CC=CC=C1 WXMKPNITSTVMEF-UHFFFAOYSA-M 0.000 description 4
229940050390 benzoate Drugs 0.000 description 3
238000003756 stirring Methods 0.000 description 3
XVMSFILGAMDHEY-UHFFFAOYSA-N 6-(4-aminophenyl)sulfonylpyridin-3-amine Chemical compound C1=CC(N)=CC=C1S(=O)(=O)C1=CC=C(N)C=N1 XVMSFILGAMDHEY-UHFFFAOYSA-N 0.000 description 2
DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 2
238000006243 chemical reaction Methods 0.000 description 2
150000001875 compounds Chemical class 0.000 description 2
238000003869 coulometry Methods 0.000 description 2
150000002334 glycols Chemical class 0.000 description 2
230000028161 membrane depolarization Effects 0.000 description 2
BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 description 2
BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical compound CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 description 2
150000003839 salts Chemical class 0.000 description 2
239000000523 sample Substances 0.000 description 2
239000012488 sample solution Substances 0.000 description 2
229910052708 sodium Inorganic materials 0.000 description 2
230000000007 visual effect Effects 0.000 description 2
239000005711 Benzoic acid Substances 0.000 description 1
OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 1
ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 1
241000220317 Rosa Species 0.000 description 1
150000001242 acetic acid derivatives Chemical class 0.000 description 1
239000003513 alkali Substances 0.000 description 1
150000004703 alkoxides Chemical class 0.000 description 1
150000001412 amines Chemical class 0.000 description 1
235000010233 benzoic acid Nutrition 0.000 description 1
MRBFBZXMHKMEKW-UHFFFAOYSA-N benzoic acid;pyridine Chemical compound C1=CC=NC=C1.OC(=O)C1=CC=CC=C1 MRBFBZXMHKMEKW-UHFFFAOYSA-N 0.000 description 1
230000015572 biosynthetic process Effects 0.000 description 1
239000011575 calcium Substances 0.000 description 1
229910052791 calcium Inorganic materials 0.000 description 1
230000001419 dependent effect Effects 0.000 description 1
238000004090 dissolution Methods 0.000 description 1
150000002148 esters Chemical class 0.000 description 1
150000002168 ethanoic acid esters Chemical class 0.000 description 1
-1 ethylene glycol monoalkyl ethers Chemical class 0.000 description 1
WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 description 1
231100001231 less toxic Toxicity 0.000 description 1
239000007788 liquid Substances 0.000 description 1
239000011777 magnesium Substances 0.000 description 1
229910052749 magnesium Inorganic materials 0.000 description 1
239000000203 mixture Substances 0.000 description 1
150000007524 organic acids Chemical class 0.000 description 1
235000005985 organic acids Nutrition 0.000 description 1
230000002688 persistence Effects 0.000 description 1
229910052697 platinum Inorganic materials 0.000 description 1
239000011591 potassium Substances 0.000 description 1
229910052700 potassium Inorganic materials 0.000 description 1
XAEFZNCEHLXOMS-UHFFFAOYSA-M potassium benzoate Chemical compound [K+].[O-]C(=O)C1=CC=CC=C1 XAEFZNCEHLXOMS-UHFFFAOYSA-M 0.000 description 1
239000004300 potassium benzoate Substances 0.000 description 1
235000010235 potassium benzoate Nutrition 0.000 description 1
229940103091 potassium benzoate Drugs 0.000 description 1
238000010992 reflux Methods 0.000 description 1
239000011734 sodium Substances 0.000 description 1
229910052712 strontium Inorganic materials 0.000 description 1
CIOAGBVUUVVLOB-UHFFFAOYSA-N strontium atom Chemical compound [Sr] CIOAGBVUUVVLOB-UHFFFAOYSA-N 0.000 description 1
230000007704 transition Effects 0.000 description 1

Classifications

- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N31/00—Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods
- G01N31/16—Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods using titration
- G01N31/168—Determining water content by using Karl Fischer reagent

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Molecular Biology (AREA)
Physics & Mathematics (AREA)
Chemical & Material Sciences (AREA)
Analytical Chemistry (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
General Physics & Mathematics (AREA)
Immunology (AREA)
Pathology (AREA)
Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)

DD81235899A 1980-12-20 1981-12-17 Pyridinfreies karl-fischer reagenz und verfahren zur bestimmung von wasser mit hilfe dieses reagenzes DD208233A5 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19803048237 DE3048237A1 (de)	1980-12-20	1980-12-20	"pyridinfreies karl-fischer-reagenz und verfahren zur bestimmung von wasser mit hilfe dieses reagenzes"

Publications (1)

Publication Number	Publication Date
DD208233A5 true DD208233A5 (de)	1984-03-28

Family

ID=6119783

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DD81235899A DD208233A5 (de)	1980-12-20	1981-12-17	Pyridinfreies karl-fischer reagenz und verfahren zur bestimmung von wasser mit hilfe dieses reagenzes

Country Status (10)

Country	Link
US (1)	US4416997A (fr)
EP (1)	EP0054713A3 (fr)
JP (1)	JPS57128848A (fr)
AU (1)	AU7733681A (fr)
BR (1)	BR8108214A (fr)
CA (1)	CA1185508A (fr)
DD (1)	DD208233A5 (fr)
DE (1)	DE3048237A1 (fr)
ES (1)	ES8304312A1 (fr)
IL (1)	IL64541A (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3204962A1 (de) *	1982-02-12	1983-08-25	Merck Patent Gmbh, 6100 Darmstadt	Karl-fischer-reagenz und verfahren zur bestimmung von wasser mit hilfe dieses reagenzes
DE3407014A1 (de) *	1984-02-27	1985-08-29	Merck Patent Gmbh, 6100 Darmstadt	Karl-fischer-reagenz und verfahren zur bestimmung von wasser mit hilfe dieses reagenzes
DE3411181A1 (de) *	1984-03-27	1985-10-10	Merck Patent Gmbh, 6100 Darmstadt	Karl-fischer-reagenz und verfahren zur bestimmung von wasser mit hilfe dieses reagenzes
DE3521544A1 (de) *	1985-06-15	1986-12-18	Merck Patent Gmbh, 6100 Darmstadt	Loesungsmittel fuer die wasserbestimmung nach karl-fischer
DE3723084A1 (de) *	1987-07-13	1989-01-26	Merck Patent Gmbh	Loesungsmittel fuer die wasserbestimmung nach karl-fischer
DE4230717C2 (de) *	1992-09-14	1996-11-28	Riedel De Haen Ag	Verfahren und Reagenz zur quantitativen Wasserbestimmung
GB9727168D0 (en) *	1997-12-24	1998-02-25	Fisher Scient U K Limited	Analytical reagent

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BE519298A (fr)	1953-04-13
FR1076005A (fr) *	1953-04-21	1954-10-21		Procédé de préparation d'un réactif pour la détermination quantitative de très petites quantités d'eau dans les gaz, les liquides et les substances solides, et réactif préparé selon ce procédé
DE1598312B1 (de) *	1967-04-19	1971-09-16	Huels Chemische Werke Ag	Anordnung zur kontinuierlichen bestimmung kleinster wasser mengen in gasen oder organischen fluessigkeiten nach der karl fischer methode
FR2234918B1 (fr) *	1973-06-26	1976-11-12	Inst Francais Du Petrole
DE2966986D1 (en) *	1979-07-26	1984-06-20	Baker Chem Co J T	Reagent for the quantitative determination of water, and its use

1980
- 1980-12-20 DE DE19803048237 patent/DE3048237A1/de not_active Withdrawn
1981
- 1981-10-29 EP EP81109183A patent/EP0054713A3/fr not_active Withdrawn
- 1981-11-10 AU AU77336/81A patent/AU7733681A/en not_active Abandoned
- 1981-12-15 IL IL64541A patent/IL64541A/xx unknown
- 1981-12-17 CA CA000392546A patent/CA1185508A/fr not_active Expired
- 1981-12-17 DD DD81235899A patent/DD208233A5/de unknown
- 1981-12-17 BR BR8108214A patent/BR8108214A/pt unknown
- 1981-12-18 JP JP56203844A patent/JPS57128848A/ja active Pending
- 1981-12-18 ES ES508138A patent/ES8304312A1/es not_active Expired
- 1981-12-21 US US06/333,100 patent/US4416997A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
JPS57128848A (en)	1982-08-10
CA1185508A (fr)	1985-04-16
EP0054713A3 (fr)	1984-02-08
IL64541A0 (en)	1982-03-31
US4416997A (en)	1983-11-22
BR8108214A (pt)	1982-10-05
AU7733681A (en)	1982-07-01
EP0054713A2 (fr)	1982-06-30
DE3048237A1 (de)	1982-07-15
IL64541A (en)	1985-07-31
ES508138A0 (es)	1983-02-16
ES8304312A1 (es)	1983-02-16

Publication	Publication Date	Title
EP0086994B1 (fr)	1987-01-07	Réactif de Karl Fischer et procédé de détermination de l'eau à l'aide de ce réactif
EP0035066B1 (fr)	1985-05-29	Réactif de titrage pour la détermination de petites quantités d'eau et procédé pour son utilisation
DE3614135A1 (de)	1986-11-06	Elektrolytloesung fuer karl fischers coulometrische titration und ihre verwendung bei der bestimmung des wassergehaltes
DE60225802T2 (de)	2009-04-16	Verfahren und gerät zum nachweis des gesamten proteingehaltes bei niedrigen ph-werten
EP0036487B1 (fr)	1984-06-20	Réactif de Karl Fischer sans pyridine et procédé de détermination de l'eau à l'aide de ce réactif
DE2603856A1 (de)	1976-09-09	Verfahren und reagentien fuer den nachweis, die schaetzung und quantitative bestimmung von nitrationen
DD208233A5 (de)	1984-03-28	Pyridinfreies karl-fischer reagenz und verfahren zur bestimmung von wasser mit hilfe dieses reagenzes
DE3407014C2 (fr)	1993-04-22
EP0687908B1 (fr)	2000-05-03	Réactif Karl Fischer
DE3447455C2 (de)	1994-07-14	Elektrolyt für die coulometrische Karl-Fischer-Titration
EP0933634B1 (fr)	2006-02-08	Utilisation d'un sel comme additif dans des réactifs Karl-Fischer pour la stabilisation du composant solvant d'éthanol
DE60037969T2 (de)	2009-03-05	Karl-fischer-reagens
EP0118063B1 (fr)	1987-04-22	Réactif pour la détection de peroxides
DE2032270A1 (de)	1970-12-23	Diagnostische Reagenzien für die Bestimmung von gamma-Glutamyltranspeptidase im menschlichen Serum
DE2335350C2 (de)	1982-08-26	Bestimmung von Calcium
DE3411181A1 (de)	1985-10-10	Karl-fischer-reagenz und verfahren zur bestimmung von wasser mit hilfe dieses reagenzes
EP0643303B1 (fr)	1999-11-10	Utilisation du N-méthylformamide dans un solvant pour la titration selon Karl Fischer
DE3709430C2 (fr)	1989-09-28
EP0358991A1 (fr)	1990-03-21	Dispositif de test pour la détermination optique de cations, d'anions ou de substances ionogènes électriquement neutres et procédé de test utilisant ce dispositif
EP0206017A2 (fr)	1986-12-30	Solution pour la détermination de l'eau selon Karl-Fischer
EP0903581B1 (fr)	2004-02-25	Réactif de Karl-Fischer
DE3008421A1 (de)	1981-09-10	Titrationsmittel und seine verwendung
DE202005011957U1 (de)	2005-11-03	Ionisierungsadditive enthaltende LC/MS-Blends
DE2608062B1 (de)	1977-08-04	Pruefroehrchen zur Bestimmung des Alkoholgehalts von Kraftstoffen
DE3011168A1 (de)	1981-10-01	Diagnostisches mittel zum nachweis von keton-koerpern