DD239793A5 - Verfahren zur herstellung von 5-alkyl-1phenyl-2-piperazino-alkylpyrazolin-3-on-verbindungen - Google Patents

Verfahren zur herstellung von 5-alkyl-1phenyl-2-piperazino-alkylpyrazolin-3-on-verbindungen Download PDF

Info

Publication number
DD239793A5
DD239793A5 DD85283095A DD28309585A DD239793A5 DD 239793 A5 DD239793 A5 DD 239793A5 DD 85283095 A DD85283095 A DD 85283095A DD 28309585 A DD28309585 A DD 28309585A DD 239793 A5 DD239793 A5 DD 239793A5
Authority
DD
German Democratic Republic
Prior art keywords
compounds
formula
alkyl
group
phenyl
Prior art date
Application number
DD85283095A
Other languages
German (de)
English (en)
Inventor
Daniel Jasserand
Marie-Odile Christen
Dominique Biard
Dimitri Yavordios
Original Assignee
������`�����@��@���������������k��
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ������`�����@��@���������������k�� filed Critical ������`�����@��@���������������k��
Publication of DD239793A5 publication Critical patent/DD239793A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/18—One oxygen or sulfur atom
    • C07D231/20—One oxygen atom attached in position 3 or 5
    • C07D231/22—One oxygen atom attached in position 3 or 5 with aryl radicals attached to ring nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DD85283095A 1984-11-24 1985-11-21 Verfahren zur herstellung von 5-alkyl-1phenyl-2-piperazino-alkylpyrazolin-3-on-verbindungen DD239793A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843442860 DE3442860A1 (de) 1984-11-24 1984-11-24 5-alkyl-1-phenyl-2-piperazinoalkylpyrazolin-3- on-verbindungen sowie verfahren und zwischenprodukte zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Publications (1)

Publication Number Publication Date
DD239793A5 true DD239793A5 (de) 1986-10-08

Family

ID=6251032

Family Applications (1)

Application Number Title Priority Date Filing Date
DD85283095A DD239793A5 (de) 1984-11-24 1985-11-21 Verfahren zur herstellung von 5-alkyl-1phenyl-2-piperazino-alkylpyrazolin-3-on-verbindungen

Country Status (18)

Country Link
US (1) US4672063A (fr)
EP (1) EP0185909B1 (fr)
JP (1) JPS61148164A (fr)
AT (1) ATE50448T1 (fr)
AU (1) AU578395B2 (fr)
CA (1) CA1247101A (fr)
DD (1) DD239793A5 (fr)
DE (2) DE3442860A1 (fr)
DK (1) DK540585A (fr)
ES (3) ES8700253A1 (fr)
FI (1) FI854603L (fr)
GR (1) GR852813B (fr)
HU (1) HU195211B (fr)
IL (1) IL77124A (fr)
NO (1) NO164351C (fr)
NZ (1) NZ214289A (fr)
PT (1) PT81545B (fr)
ZA (1) ZA858418B (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3782525T2 (de) * 1986-02-27 1993-05-27 Duphar Int Res Aryl-substituierte(n-piperidinyl)methyl und (n-piperazinyl)methylazole mit antipsychotischer wirkung.
FR2648135B1 (fr) * 1989-06-07 1991-09-27 Pf Medicament Derives de phenyl-1-dihydro-1,4 amino-3 oxo-4 pyridazines, leur preparation et leur application en therapeutique
FR2676733B1 (fr) * 1991-05-22 1993-10-01 Fabre Medicament Pierre Derives de phenyl-1 dihydro-1,4 hydroxy-3 oxo-4 pyridazines, leur preparation et leur application en therapeutique.
US5219856A (en) * 1992-04-06 1993-06-15 E. I. Du Pont De Nemours And Company Angiotensin-II receptor blocking, heterocycle substituted imidazoles
US7589199B2 (en) 2002-06-12 2009-09-15 Chemocentryx, Inc. Substituted piperazines
US20050256130A1 (en) * 2002-06-12 2005-11-17 Chemocentryx, Inc. Substituted piperazines
EP1531822B1 (fr) * 2002-06-12 2009-08-05 ChemoCentryx Inc Derives de piperazine 1-aryl-4-substitues utilises en tant qu'antagonistes du ccr1 dans le traitement de l'inflammation et des troubles immunitaires
US7842693B2 (en) * 2002-06-12 2010-11-30 Chemocentryx, Inc. Substituted piperazines
US7435830B2 (en) * 2004-03-03 2008-10-14 Chemocentryx, Inc. Bicyclic and bridged nitrogen heterocycles
US7435831B2 (en) * 2004-03-03 2008-10-14 Chemocentryx, Inc. Bicyclic and bridged nitrogen heterocycles
BRPI0708337A2 (pt) 2006-02-28 2011-05-24 Helicon Therapeutics Inc pipirazinas terapêutica como inibidores pde4
US8927546B2 (en) * 2006-02-28 2015-01-06 Dart Neuroscience (Cayman) Ltd. Therapeutic piperazines
JP2008148592A (ja) * 2006-12-15 2008-07-03 Sk Sangyo Kk 防風網

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3169966A (en) * 1961-01-24 1965-02-16 Ciba Geigy Corp Aminopyrazoles
US3362956A (en) * 1965-08-19 1968-01-09 Sterling Drug Inc 1-[(heterocyclyl)-lower-alkyl]-4-substituted-piperazines
IT1052130B (it) * 1973-10-15 1981-06-20 Sigma Tau Ind Farmaceuti Derivati del triazolinone e procedimento per la loro preparazione
DE3132916A1 (de) * 1981-08-20 1983-03-03 Kali-Chemie Pharma Gmbh, 3000 Hannover 1-phenylindazol-3-on-verbindungen sowie verfahren und zwischenprodukte zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3132915A1 (de) * 1981-08-20 1983-03-03 Kali-Chemie Pharma Gmbh, 3000 Hannover 1,5-diphenylpyrazolin-3-on-verbindungen sowie verfahren und zwischenprodukte zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Also Published As

Publication number Publication date
PT81545B (pt) 1988-01-22
CA1247101A (fr) 1988-12-20
EP0185909B1 (fr) 1990-02-21
NO164351C (no) 1990-09-26
HUT38927A (en) 1986-07-28
ATE50448T1 (de) 1990-03-15
ES549176A0 (es) 1986-10-01
JPS61148164A (ja) 1986-07-05
PT81545A (en) 1985-12-01
NO854677L (no) 1986-05-26
ES8703870A1 (es) 1987-03-01
ZA858418B (en) 1986-07-30
NZ214289A (en) 1988-10-28
EP0185909A1 (fr) 1986-07-02
DE3576075D1 (de) 1990-03-29
HU195211B (en) 1988-04-28
AU578395B2 (en) 1988-10-20
DK540585A (da) 1986-05-25
US4672063A (en) 1987-06-09
ES8700253A1 (es) 1986-10-01
FI854603A0 (fi) 1985-11-21
ES8703869A1 (es) 1987-03-01
ES555006A0 (es) 1987-03-01
FI854603A7 (fi) 1986-05-25
ES555007A0 (es) 1987-03-01
AU5035085A (en) 1986-07-17
IL77124A0 (en) 1986-04-29
IL77124A (en) 1990-03-19
NO164351B (no) 1990-06-18
GR852813B (fr) 1986-03-21
DK540585D0 (da) 1985-11-22
DE3442860A1 (de) 1986-05-28
FI854603L (fi) 1986-05-25

Similar Documents

Publication Publication Date Title
DE2058295C3 (de) Xanthen-9-on-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DE3132882A1 (de) Neue piperazinone, ihre herstellung und verwendung
EP0013894B1 (fr) Aryléthers, procédé pour leur préparation et médicaments les contenant
EP0005828B1 (fr) Nouvelles dérivés de la phénylpipérazine substitués, médicaments les contenant et procédés pour leur préparation
DD239793A5 (de) Verfahren zur herstellung von 5-alkyl-1phenyl-2-piperazino-alkylpyrazolin-3-on-verbindungen
EP0183159A2 (fr) 1-Hétéroaryl-4-aryl-pyrazolin-5-ones pour application en tant que médicaments
EP0041215B1 (fr) Imidazoazolalkénylcarboxamides, intermédiaires pour leur préparation, leur préparation et leur application comme médicaments
EP0072960B1 (fr) Composés 1,5-diphénylpyrazolin-3-one, ainsi qu'un procédé et produits intermédiaires pour leur fabrication et médicaments contenant ces composés
DD216014A5 (de) Verfahren zur herstellung von verbindungen mit einem heterocyclischen distickstoffkern
DE3813531A1 (de) Neue 2-aminoalkyl-4-benzyl-1-(2h)-phthalazinon-derivate
DE2800316A1 (de) Oximether enthaltende arzneimittel zur bekaempfung von ulcera, oximether und verfahren zu ihrer herstellung
EP0072961B1 (fr) Composés 1-phénylindazol-3-one ainsi qu'un procédé et produits intermédiaires pour leur fabrication et médicaments contenant ces composés
DE2404050A1 (de) Neue heterocyclische vrbindungen und verfahren zu deren herstellung
EP0224159B1 (fr) Composés pyridiniques substitués par des groupes basiques, leur procédé de préparation, médicaments les contenant et leur application
DE3038593A1 (de) Neue entzuendungshemmende und immunregulatorische pyridine und pyrimidine
EP0123700A1 (fr) Acides picoliniques substitués, leur procédé de préparation, leur application, et les médicaments les contenant
DE1076691B (de) Verfahren zur Herstellung von Phenthiazinderivaten
CH634069A5 (en) Process for preparing novel 7-substituted 7H-pyrrolo[3,2-f]quinazoline-1,3-diamines
EP0110298B1 (fr) Dérivés d'acridanone
DD210266A5 (de) Verfahren zur herstellung von 3-(ureidocyclohexylamino)-propan-1,2-diolderivaten
CH641800A5 (de) Pyrido-pyrimidine, verfahren zu ihrer herstellung und die diese verbindungen enthaltenden arzneimittel.
EP0488008A1 (fr) Dérivés de piperazinoalkylbenzoxazine et -thiazine substitués par un hétérocycle, leur procédé de préparation et médicaments les contenant
DE1904081A1 (de) Benzoxazinderivate und Verfahren ? Herstellung
DE69310186T2 (de) 1,2-dihydro-2-oxo-3-aminochinoxalin derivate, ihre verwendung als heilmittel
DE2641291A1 (de) 2-cyano-3- oder 4-(substituiertes amino)-oxanilsaeure-derivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel

Legal Events

Date Code Title Description
ENJ Ceased due to non-payment of renewal fee