DD283631A5 - Verfahren zur herstellung aromatisch substituierter araliphatylaminoalkandiphosphonsaeuren - Google Patents

Verfahren zur herstellung aromatisch substituierter araliphatylaminoalkandiphosphonsaeuren Download PDF

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Publication number
DD283631A5
DD283631A5 DD88322931A DD32293188A DD283631A5 DD 283631 A5 DD283631 A5 DD 283631A5 DD 88322931 A DD88322931 A DD 88322931A DD 32293188 A DD32293188 A DD 32293188A DD 283631 A5 DD283631 A5 DD 283631A5
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DD
German Democratic Republic
Prior art keywords
formula
radical
alk
hydrogen
alkyl
Prior art date
Application number
DD88322931A
Other languages
German (de)
English (en)
Inventor
Knut A Jaeggi
Original Assignee
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Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ���@����������@��k�� filed Critical ���@����������@��k��
Publication of DD283631A5 publication Critical patent/DD283631A5/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/44—Amides thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3839—Polyphosphonic acids
    • C07F9/3873—Polyphosphonic acids containing nitrogen substituent, e.g. N.....H or N-hydrocarbon group which can be substituted by halogen or nitro(so), N.....O, N.....S, N.....C(=X)- (X =O, S), N.....N, N...C(=X)...N (X =O, S)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/576—Six-membered rings
    • C07F9/58—Pyridine rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6503—Five-membered rings
    • C07F9/6506—Five-membered rings having the nitrogen atoms in positions 1 and 3

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Nutrition Science (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Detergent Compositions (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Anti-Oxidant Or Stabilizer Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pyridine Compounds (AREA)
  • Steroid Compounds (AREA)
DD88322931A 1987-12-11 1988-12-09 Verfahren zur herstellung aromatisch substituierter araliphatylaminoalkandiphosphonsaeuren DD283631A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH484787 1987-12-11

Publications (1)

Publication Number Publication Date
DD283631A5 true DD283631A5 (de) 1990-10-17

Family

ID=4283590

Family Applications (1)

Application Number Title Priority Date Filing Date
DD88322931A DD283631A5 (de) 1987-12-11 1988-12-09 Verfahren zur herstellung aromatisch substituierter araliphatylaminoalkandiphosphonsaeuren

Country Status (21)

Country Link
EP (1) EP0320455B1 (es)
JP (1) JPH01197495A (es)
KR (1) KR890009956A (es)
AT (1) ATE90353T1 (es)
AU (1) AU609549B2 (es)
CA (1) CA1329609C (es)
DD (1) DD283631A5 (es)
DE (1) DE3881659D1 (es)
DK (1) DK688488A (es)
ES (1) ES2054868T3 (es)
FI (1) FI92704C (es)
HU (1) HU202880B (es)
IE (1) IE62738B1 (es)
IL (1) IL88620A (es)
MX (1) MX14109A (es)
NO (1) NO176663C (es)
NZ (1) NZ227273A (es)
PH (1) PH26416A (es)
PT (1) PT89193B (es)
YU (1) YU221388A (es)
ZA (1) ZA889157B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW198039B (es) * 1988-11-28 1993-01-11 Ciba Geigy Ag
US5270365A (en) * 1991-12-17 1993-12-14 Merck & Co., Inc. Prevention and treatment of periodontal disease with alendronate
US5763611A (en) * 1992-05-29 1998-06-09 The Procter & Gamble Company Thio-substituted cyclic phosphonate compounds, pharmaceutical compositions, and methods for treating abnormal calcium and phosphate metabolism
ES2118967T3 (es) * 1992-05-29 1998-10-01 Procter & Gamble Pharma Compuestos de fosfonato que contienen nitrogeno cuaternario para tratar un metabolismo anormal del calcio y fosfato asi como el calculo y la placa dentales.
US5391743A (en) * 1992-05-29 1995-02-21 Procter & Gamble Pharmaceuticals, Inc. Quaternary nitrogen-containing phosphonate compounds, pharmaceutical compositions, and methods of treating abnormal calcium and phosphate metabolism and methods of treating and preventing dental calculus and plaque
EP0642521A1 (en) * 1992-05-29 1995-03-15 Procter & Gamble Pharmaceuticals Thio-substituted nitrogen-containing heterocyclic phosphonate compounds for treating abnormal calcium and phosphate metabolism
US5753634A (en) * 1992-05-29 1998-05-19 The Procter & Gamble Company Quaternary nitrogen containing phosphonate compounds, pharmaceutical compostions, and methods for treating abnormal calcium and phosphate metabolism
HUT69699A (en) * 1992-05-29 1995-09-28 Procter & Gamble Pharma Sulfur-containing phosphonate compounds for treating abnormal calcium and phosphate metabolism
NZ253631A (en) * 1992-06-30 1997-02-24 Procter & Gamble Pharma Phosphonate or nsaid pharmaceutical compositions for treating arthritis
JP2017504060A (ja) * 2013-12-19 2017-02-02 スリーエム イノベイティブ プロパティズ カンパニー リン表面処理剤を有するナノ粒子を含む自己集合層を含む物品

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL77243A (en) * 1984-12-21 1996-11-14 Procter & Gamble Pharmaceutical compositions containing geminal diphosphonic acid compounds and certain such novel compounds
PH27078A (en) * 1984-12-21 1993-02-01 Procter & Gamble Pharmaceutical compositions containing geminal diphosphonates
DE3623397A1 (de) * 1986-07-11 1988-01-14 Boehringer Mannheim Gmbh Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel

Also Published As

Publication number Publication date
PH26416A (en) 1992-07-15
DE3881659D1 (en) 1993-07-15
NO176663C (no) 1995-05-10
DK688488D0 (da) 1988-12-09
AU609549B2 (en) 1991-05-02
FI885710A7 (fi) 1989-06-12
IE883680L (en) 1989-06-11
DK688488A (da) 1989-06-12
ES2054868T3 (es) 1994-08-16
NO885489L (no) 1989-06-12
YU221388A (en) 1990-06-30
KR890009956A (ko) 1989-08-05
ZA889157B (en) 1989-07-26
FI92704B (fi) 1994-09-15
EP0320455A1 (de) 1989-06-14
IL88620A0 (en) 1989-07-31
ATE90353T1 (de) 1993-06-15
FI92704C (fi) 1994-12-27
NO176663B (no) 1995-01-30
AU2673888A (en) 1989-06-15
PT89193A (pt) 1989-12-29
NO885489D0 (no) 1988-12-09
PT89193B (pt) 1993-06-30
EP0320455B1 (de) 1993-06-09
IL88620A (en) 1994-11-28
HUT48899A (en) 1989-07-28
FI885710A0 (fi) 1988-12-09
MX14109A (es) 1994-02-28
NZ227273A (en) 1991-06-25
JPH01197495A (ja) 1989-08-09
CA1329609C (en) 1994-05-17
HU202880B (en) 1991-04-29
IE62738B1 (en) 1995-02-22

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