DD291700A5 - Verfahren zur herstellung eines therapeutischen systems zur transdermalen oder transmucosalen verabreichung von wirkstoffen und seine verwendung - Google Patents
Verfahren zur herstellung eines therapeutischen systems zur transdermalen oder transmucosalen verabreichung von wirkstoffen und seine verwendung Download PDFInfo
- Publication number
- DD291700A5 DD291700A5 DD90337634A DD33763490A DD291700A5 DD 291700 A5 DD291700 A5 DD 291700A5 DD 90337634 A DD90337634 A DD 90337634A DD 33763490 A DD33763490 A DD 33763490A DD 291700 A5 DD291700 A5 DD 291700A5
- Authority
- DD
- German Democratic Republic
- Prior art keywords
- reservoir
- parts
- intermediate layer
- reservoir parts
- layer
- Prior art date
Links
- 230000001225 therapeutic effect Effects 0.000 title claims abstract description 12
- 238000000034 method Methods 0.000 title claims description 10
- 239000013543 active substance Substances 0.000 title abstract description 9
- 238000004519 manufacturing process Methods 0.000 title description 6
- 239000010410 layer Substances 0.000 claims abstract description 29
- 239000000853 adhesive Substances 0.000 claims abstract description 9
- 239000011241 protective layer Substances 0.000 claims abstract description 4
- 238000009826 distribution Methods 0.000 claims abstract description 3
- 239000004480 active ingredient Substances 0.000 claims description 9
- 230000008569 process Effects 0.000 claims description 5
- 239000004615 ingredient Substances 0.000 claims description 4
- 239000000463 material Substances 0.000 claims description 3
- 239000011888 foil Substances 0.000 claims description 2
- 239000002905 metal composite material Substances 0.000 claims description 2
- 239000000546 pharmaceutical excipient Substances 0.000 claims description 2
- 238000002360 preparation method Methods 0.000 claims description 2
- 239000003814 drug Substances 0.000 description 8
- 229940079593 drug Drugs 0.000 description 7
- 238000003475 lamination Methods 0.000 description 7
- 238000003856 thermoforming Methods 0.000 description 4
- 230000008901 benefit Effects 0.000 description 3
- 238000010030 laminating Methods 0.000 description 2
- 239000012528 membrane Substances 0.000 description 2
- 238000003825 pressing Methods 0.000 description 2
- 230000004913 activation Effects 0.000 description 1
- 239000002313 adhesive film Substances 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000011065 in-situ storage Methods 0.000 description 1
- 238000010348 incorporation Methods 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 150000003384 small molecules Chemical class 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7092—Transdermal patches having multiple drug layers or reservoirs, e.g. for obtaining a specific release pattern, or for combining different drugs
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Media Introduction/Drainage Providing Device (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Polyesters Or Polycarbonates (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3903794A DE3903794A1 (de) | 1989-02-09 | 1989-02-09 | Therapeutisches system zur transdermalen oder transmucosalen verabreichung von wirkstoffen und seine verwendung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DD291700A5 true DD291700A5 (de) | 1991-07-11 |
Family
ID=6373693
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DD90337634A DD291700A5 (de) | 1989-02-09 | 1990-02-06 | Verfahren zur herstellung eines therapeutischen systems zur transdermalen oder transmucosalen verabreichung von wirkstoffen und seine verwendung |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US5128137A (fr) |
| EP (1) | EP0382129B1 (fr) |
| JP (1) | JP2538371B2 (fr) |
| AT (1) | ATE95711T1 (fr) |
| CA (1) | CA2009558C (fr) |
| DD (1) | DD291700A5 (fr) |
| DE (2) | DE3903794A1 (fr) |
| DK (1) | DK0382129T3 (fr) |
| ES (1) | ES2047171T3 (fr) |
| FI (1) | FI105156B (fr) |
| IE (1) | IE64835B1 (fr) |
| NO (1) | NO180670C (fr) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1742621B2 (fr) † | 2004-04-26 | 2011-10-12 | Grünenthal GmbH | Systeme de liberation de principe actif constitue d'un timbre adhesif contenant le principe actif et d'au moins un regulateur de liberation de principe actif |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUT65957A (en) † | 1992-03-17 | 1994-08-29 | Becton Dickinson Co | User operated iontophoretical device and method for manufacturing it |
| JP2542792B2 (ja) * | 1992-11-05 | 1996-10-09 | ベクトン・ディッキンソン・アンド・カンパニー | ユ―ザ作動型のイオン導入式装置 |
| US5445609A (en) * | 1993-05-28 | 1995-08-29 | Alza Corporation | Electrotransport agent delivery device having a disposable component and a removable liner |
| US5962011A (en) * | 1993-12-06 | 1999-10-05 | Schering-Plough Healthcare Products, Inc. | Device for delivery of dermatological ingredients |
| FR2728463A1 (fr) * | 1994-12-21 | 1996-06-28 | Lhd Lab Hygiene Dietetique | Systeme transdermique d'administration simultanee de plusieurs principes actifs |
| US20040265353A1 (en) * | 1995-07-28 | 2004-12-30 | Zars, Inc. | Systems and methods for treating panic attacks |
| US6284266B1 (en) | 1995-07-28 | 2001-09-04 | Zars, Inc. | Methods and apparatus for improved administration of fentanyl and sufentanil |
| US5658583A (en) * | 1995-07-28 | 1997-08-19 | Zhang; Jie | Apparatus and methods for improved noninvasive dermal administration of pharmaceuticals |
| US6245347B1 (en) * | 1995-07-28 | 2001-06-12 | Zars, Inc. | Methods and apparatus for improved administration of pharmaceutically active compounds |
| GB9515807D0 (en) * | 1995-08-02 | 1995-10-04 | Cantwell Evelyna D | Topical hyperbaric bandage |
| DE29514849U1 (de) * | 1995-09-15 | 1995-11-16 | Weyergans, Rudolf, 52355 Düren | Cellulitis-Pflaster |
| US5797867A (en) * | 1996-09-27 | 1998-08-25 | Becton Dickinson And Company | Iontophoretic drug delivery system, including method for activating same for attachment to patient |
| US5738647A (en) * | 1996-09-27 | 1998-04-14 | Becton Dickinson And Company | User activated iontophoretic device and method for activating same |
| US6955819B2 (en) | 1998-09-29 | 2005-10-18 | Zars, Inc. | Methods and apparatus for using controlled heat to regulate transdermal and controlled release delivery of fentanyl, other analgesics, and other medical substances |
| US6726673B1 (en) | 1999-05-24 | 2004-04-27 | Zars, Inc. | Methods and apparatus for improved administration of testosterone pharmaceuticals |
| US6453648B1 (en) | 1999-07-06 | 2002-09-24 | Zars, Inc. | Method for manufacturing a heat generating apparatus |
| US6261595B1 (en) | 2000-02-29 | 2001-07-17 | Zars, Inc. | Transdermal drug patch with attached pocket for controlled heating device |
| WO2001091637A1 (fr) * | 2000-05-29 | 2001-12-06 | Medicotest A/S | Electrode permettant d'etablir un contact electrique avec la peau |
| US6767342B1 (en) | 2001-04-23 | 2004-07-27 | Evelyna D. Cantwell | Oxygen bandage system |
| US8524272B2 (en) * | 2003-08-15 | 2013-09-03 | Mylan Technologies, Inc. | Transdermal patch incorporating active agent migration barrier layer |
| US20060099247A1 (en) * | 2004-11-10 | 2006-05-11 | Byrd-Walsh, Llc. | Liquid, gas and/or vapor phase delivery systems |
| DE102004062614B4 (de) * | 2004-12-24 | 2011-12-29 | Lts Lohmann Therapie-Systeme Ag | Transdermales therapeutisches System mit aktivierbarer Übersättigung und kontrollierter Permeationförderung sowie Verfahren zu dessen Herstellung |
| US7955677B2 (en) | 2005-12-07 | 2011-06-07 | Mylan Technologies, Inc. | Two-sided non-stick release film |
| DE102007016684A1 (de) * | 2007-04-04 | 2008-10-09 | Dr. Schumacher Gmbh | Biologisch abbaubares Mehrschichtsystem |
| US20090304776A1 (en) * | 2008-06-06 | 2009-12-10 | Totada Shantha | Transmucosal delivery of therapeutic agents and methods of use thereof |
| CA2735789C (fr) * | 2008-09-05 | 2016-10-11 | Travanti Pharma Inc. | Conditionnement pour delivrance de medicaments ionophoretiques |
| US9012477B2 (en) * | 2009-01-06 | 2015-04-21 | Nuvo Research Inc. | Method of treating neuropathic pain |
| CA2757302A1 (fr) * | 2009-04-01 | 2010-10-07 | Andrew Crockett | Methodes de traitement des douleurs myofasciales, musculaires et/ou dorsales |
| US9186334B2 (en) | 2009-05-04 | 2015-11-17 | Nuvo Research Inc. | Heat assisted lidocaine and tetracaine for transdermal analgesia |
| WO2010129542A1 (fr) * | 2009-05-04 | 2010-11-11 | Jie Zhang | Méthodes de traitement des douleurs associées au névrome, au syndrome canalaire et à d'autres pathologies |
| US9693976B2 (en) | 2010-01-14 | 2017-07-04 | Crescita Therapeutics Inc. | Solid-forming local anesthetic formulations for pain control |
| GB201019761D0 (en) * | 2010-11-22 | 2011-01-05 | Chowdhury Dewan F H | Multilayered transdermal patch |
| AU2011332187B2 (en) | 2010-11-23 | 2016-03-03 | Teva Pharmaceuticals International Gmbh | User-activated self-contained co-packaged iontophoretic drug delivery system |
| US8696637B2 (en) * | 2011-02-28 | 2014-04-15 | Kimberly-Clark Worldwide | Transdermal patch containing microneedles |
| ES2967531T3 (es) * | 2013-02-12 | 2024-04-30 | Fraunhofer Ges Forschung | Lámina de separación recubierta de silicona con una capacidad especial de embutición en vacío |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL107185C (fr) * | 1957-12-19 | |||
| FR2562800A1 (fr) * | 1984-04-11 | 1985-10-18 | Fournier Laboratoires | Dispositif pour l'administration percutanee de medicaments |
| US4627429A (en) * | 1986-02-28 | 1986-12-09 | American Home Products Corporation | Storage-stable transdermal adhesive patch |
| EP0249475A3 (fr) * | 1986-06-13 | 1989-10-11 | Alza Corporation | Délivrance percutanée retardée |
| US4906169A (en) * | 1986-12-29 | 1990-03-06 | Rutgers, The State University Of New Jersey | Transdermal estrogen/progestin dosage unit, system and process |
| US5023084A (en) * | 1986-12-29 | 1991-06-11 | Rutgers, The State University Of New Jersey | Transdermal estrogen/progestin dosage unit, system and process |
| US5000956A (en) * | 1987-03-09 | 1991-03-19 | Alza Corporation | Prevention of contact allergy by coadministration of a corticosteroid with a sensitizing drug |
| US4764379A (en) * | 1987-08-24 | 1988-08-16 | Alza Corporation | Transdermal drug delivery device with dual permeation enhancers |
| US4885154A (en) * | 1988-03-01 | 1989-12-05 | Alza Corporation | Method for reducing sensitization or irritation in transdermal drug delivery and means therefor |
-
1989
- 1989-02-09 DE DE3903794A patent/DE3903794A1/de active Granted
-
1990
- 1990-02-03 EP EP90102174A patent/EP0382129B1/fr not_active Expired - Lifetime
- 1990-02-03 DE DE90102174T patent/DE59003039D1/de not_active Expired - Fee Related
- 1990-02-03 ES ES90102174T patent/ES2047171T3/es not_active Expired - Lifetime
- 1990-02-03 AT AT90102174T patent/ATE95711T1/de not_active IP Right Cessation
- 1990-02-03 DK DK90102174.1T patent/DK0382129T3/da active
- 1990-02-06 DD DD90337634A patent/DD291700A5/de not_active IP Right Cessation
- 1990-02-06 US US07/475,609 patent/US5128137A/en not_active Expired - Lifetime
- 1990-02-07 JP JP2026213A patent/JP2538371B2/ja not_active Expired - Fee Related
- 1990-02-08 CA CA002009558A patent/CA2009558C/fr not_active Expired - Lifetime
- 1990-02-08 NO NO900604A patent/NO180670C/no not_active IP Right Cessation
- 1990-02-08 IE IE45190A patent/IE64835B1/xx not_active IP Right Cessation
- 1990-02-08 FI FI900622A patent/FI105156B/fi active IP Right Grant
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1742621B2 (fr) † | 2004-04-26 | 2011-10-12 | Grünenthal GmbH | Systeme de liberation de principe actif constitue d'un timbre adhesif contenant le principe actif et d'au moins un regulateur de liberation de principe actif |
Also Published As
| Publication number | Publication date |
|---|---|
| NO180670C (no) | 1997-05-28 |
| EP0382129B1 (fr) | 1993-10-13 |
| ATE95711T1 (de) | 1993-10-15 |
| JP2538371B2 (ja) | 1996-09-25 |
| DE3903794A1 (de) | 1990-08-16 |
| US5128137A (en) | 1992-07-07 |
| EP0382129A3 (fr) | 1991-02-27 |
| IE64835B1 (en) | 1995-09-06 |
| CA2009558C (fr) | 1996-08-06 |
| EP0382129A2 (fr) | 1990-08-16 |
| DE59003039D1 (de) | 1993-11-18 |
| NO180670B (no) | 1997-02-17 |
| CA2009558A1 (fr) | 1990-08-09 |
| ES2047171T3 (es) | 1994-02-16 |
| FI900622A0 (fi) | 1990-02-08 |
| JPH02264715A (ja) | 1990-10-29 |
| FI105156B (fi) | 2000-06-30 |
| IE900451L (en) | 1990-08-09 |
| NO900604D0 (no) | 1990-02-08 |
| DK0382129T3 (da) | 1994-02-14 |
| DE3903794C2 (fr) | 1992-07-16 |
| NO900604L (no) | 1990-08-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ENJ | Ceased due to non-payment of renewal fee |