DE112010000006B8 - Verfahren zur Herstellung von nano-dispergierten high-all-trans-Carotinoid-Mikrokapseln - Google Patents

Verfahren zur Herstellung von nano-dispergierten high-all-trans-Carotinoid-Mikrokapseln Download PDF

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Publication number
DE112010000006B8
DE112010000006B8 DE112010000006T DE112010000006T DE112010000006B8 DE 112010000006 B8 DE112010000006 B8 DE 112010000006B8 DE 112010000006 T DE112010000006 T DE 112010000006T DE 112010000006 T DE112010000006 T DE 112010000006T DE 112010000006 B8 DE112010000006 B8 DE 112010000006B8
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DE
Germany
Prior art keywords
nano
preparation
trans carotenoid
dispersed high
carotenoid microcapsules
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Application number
DE112010000006T
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DE112010000006T5 (de
DE112010000006B4 (de
Inventor
Jianfeng Chen
Zhirong Chen
Guangwen Chu
Dan Qiu
Lei Shao
Lifang Shi
Hong Yin
Hong Zhao
Jiandong Li
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beijing University of Chemical Technology
Zhejiang University ZJU
Zhejiang NHU Co Ltd
Original Assignee
Beijing University of Chemical Technology
Zhejiang University ZJU
Zhejiang NHU Co Ltd
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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/04—Making microcapsules or microballoons by physical processes, e.g. drying, spraying
    • B01J13/043—Drying and spraying
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/179—Colouring agents, e.g. pigmenting or dyeing agents
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L5/00—Preparation or treatment of foods or foodstuffs, in general; Food or foodstuffs obtained thereby; Materials therefor
    • A23L5/40—Colouring or decolouring of foods
    • A23L5/42—Addition of dyes or pigments, e.g. in combination with optical brighteners
    • A23L5/43—Addition of dyes or pigments, e.g. in combination with optical brighteners using naturally occurring organic dyes or pigments, their artificial duplicates or their derivatives
    • A23L5/44—Addition of dyes or pigments, e.g. in combination with optical brighteners using naturally occurring organic dyes or pigments, their artificial duplicates or their derivatives using carotenoids or xanthophylls
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
    • A23P10/00—Shaping or working of foodstuffs characterised by the products
    • A23P10/30—Encapsulation of particles, e.g. foodstuff additives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/01—Hydrocarbons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0241—Containing particulates characterized by their shape and/or structure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/11—Encapsulated compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/31—Hydrocarbons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/35—Ketones, e.g. benzophenone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B61/00—Dyes of natural origin prepared from natural sources, e.g. vegetable sources
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B67/00—Influencing the physical, e.g. the dyeing or printing properties of dyestuffs without chemical reactions, e.g. by treating with solvents grinding or grinding assistants, coating of pigments or dyes; Process features in the making of dyestuff preparations; Dyestuff preparations of a special physical nature, e.g. tablets, films
    • C09B67/0097—Dye preparations of special physical nature; Tablets, films, extrusion, microcapsules, sheets, pads, bags with dyes
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/41—Particular ingredients further characterized by their size
    • A61K2800/412—Microsized, i.e. having sizes between 0.1 and 100 microns

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Birds (AREA)
  • Organic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Zoology (AREA)
  • Dermatology (AREA)
  • Animal Husbandry (AREA)
  • Botany (AREA)
  • Medicinal Preparation (AREA)
  • Fodder In General (AREA)
DE112010000006T 2009-03-30 2010-03-18 Verfahren zur Herstellung von nano-dispergierten high-all-trans-Carotinoid-Mikrokapseln Active DE112010000006B8 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN200910097063.2 2009-03-30
CN2009100970632A CN101549273B (zh) 2009-03-30 2009-03-30 纳米分散的高全反式类胡萝卜素微胶囊的制备方法
PCT/CN2010/071121 WO2010111912A1 (zh) 2009-03-30 2010-03-18 纳米分散的高全反式类胡萝卜素微胶囊的制备方法

Publications (3)

Publication Number Publication Date
DE112010000006T5 DE112010000006T5 (de) 2012-06-21
DE112010000006B4 DE112010000006B4 (de) 2013-05-08
DE112010000006B8 true DE112010000006B8 (de) 2013-09-12

Family

ID=41153902

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DE112010000006T Active DE112010000006B8 (de) 2009-03-30 2010-03-18 Verfahren zur Herstellung von nano-dispergierten high-all-trans-Carotinoid-Mikrokapseln

Country Status (4)

Country Link
US (1) US8540908B2 (de)
CN (1) CN101549273B (de)
DE (1) DE112010000006B8 (de)
WO (1) WO2010111912A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101549273B (zh) * 2009-03-30 2011-06-15 浙江新和成股份有限公司 纳米分散的高全反式类胡萝卜素微胶囊的制备方法
US9173818B2 (en) * 2011-03-25 2015-11-03 Zhejiang Nhu Company Ltd Method for preparing stable-type vitamin A microcapsules continuously
EP2559481A1 (de) * 2011-08-16 2013-02-20 Basf Se Verfahren zur Verkapselung von Substanzen unter Ausbildung der Kapselhülle durch Grenzflächenreaktion im Zentrifugalreaktor
CN102362864B (zh) * 2011-10-26 2013-03-13 浙江新维普添加剂有限公司 提高维生素a或维生素d3微胶囊流散性和堆密度的方法
CN103005458B (zh) * 2012-12-20 2014-11-05 宁波大学 一种盐生杜氏藻β-胡萝卜素微胶囊及其制备方法
CN103284290B (zh) * 2013-05-24 2015-04-08 肇庆巨元生化有限公司 一种良好的类胡萝卜素的微囊化方法
CN104274428B (zh) 2013-07-09 2016-04-13 浙江新维普添加剂有限公司 油分散性类胡萝卜素制剂的制备方法
WO2017168006A1 (en) * 2016-04-01 2017-10-05 Dsm Ip Assets B.V. Beverages comprising stable granules of milled lutein
CN107114796B (zh) * 2017-05-31 2020-10-23 江苏鑫缘丝绸科技有限公司 一种纳米蚕蛹蛋白粉及其制备方法
CN107594597B (zh) * 2017-07-31 2020-05-12 浙江新和成股份有限公司 一种脂溶性营养素微胶囊及其制备方法
CN108148444B (zh) * 2017-12-29 2020-08-11 嘉必优生物技术（武汉）股份有限公司 一种用于着色的高含量β-胡萝卜素微胶囊的制备方法
WO2019207084A1 (en) * 2018-04-27 2019-10-31 Dsm Ip Assets B.V. Method of manufacturing spray-dried powders
CN110499043B (zh) * 2018-05-17 2020-12-25 北京化工大学 一种纳米分散染料的制备方法
CN109156827A (zh) * 2018-09-20 2019-01-08 武汉星辰现代生物工程有限公司 一种高生物利用度红色系β-胡萝卜素制剂的制备方法
CN111419821B (zh) * 2020-04-17 2022-08-02 万华化学集团股份有限公司 一种高全反式类胡萝卜素微胶囊的制备方法
CN113841895A (zh) * 2021-11-16 2021-12-28 湖北欣和生物科技有限公司 一种β-胡萝卜素微囊粉末的制备方法
CN114287625B (zh) * 2021-12-28 2024-04-05 大连医诺生物股份有限公司 一种类胡萝卜素制剂及其应用
CN118525919A (zh) * 2023-02-22 2024-08-23 浙江可明生物医药有限公司 类胡萝卜素制剂的制备方法

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3998753A (en) * 1974-08-13 1976-12-21 Hoffmann-La Roche Inc. Water dispersible carotenoid preparations and processes thereof
EP0065193A2 (de) * 1981-05-15 1982-11-24 BASF Aktiengesellschaft Verfahren zur Herstellung von feinverteilten, pulverförmigen Carotinoid- bzw. Retinoidpräparaten
WO1991006292A1 (en) * 1989-11-02 1991-05-16 Danochemo A/S Process of preparing a water dispersible hydrophobic or aerophilic solid
WO2003017785A1 (en) * 2001-08-23 2003-03-06 Dsm Ip Assets B.V. Novel stabilized carotenoid compositions
US20050037115A1 (en) * 2003-08-15 2005-02-17 Linda Fullmer Carotenoid nanodispersions for use in water-based systems and a process for their preparation

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DK19393D0 (da) 1993-02-19 1993-02-19 Danochemo As Fremgangsmaade til fremstilling af et i vand dispergerbart pulverformigt carotenoidpraeparat
JP3555640B2 (ja) * 1996-05-10 2004-08-18 ライオン株式会社 天然カロチノイドを包含した多芯型構造のマイクロカプセル並びに錠剤、食品用及び医薬品用配合剤
US6663900B2 (en) * 2002-02-01 2003-12-16 Kemin Foods, Lc Microcapsules having high carotenoid content
EP1802279A1 (de) * 2004-09-29 2007-07-04 Michael Ary Bos Caratenoid-zusammensetzung und verfahren zu ihrer herstellung
CN100421650C (zh) * 2005-03-23 2008-10-01 浙江新和成股份有限公司 水分散性类胡萝卜素粉的制备方法
US8613946B2 (en) * 2006-12-21 2013-12-24 Isp Investment Inc. Carotenoids of enhanced bioavailability
CN100500652C (zh) * 2007-02-12 2009-06-17 浙江大学 一种高全反式β-胡萝卜素制剂的制备方法
CN101549273B (zh) * 2009-03-30 2011-06-15 浙江新和成股份有限公司 纳米分散的高全反式类胡萝卜素微胶囊的制备方法

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3998753A (en) * 1974-08-13 1976-12-21 Hoffmann-La Roche Inc. Water dispersible carotenoid preparations and processes thereof
EP0065193A2 (de) * 1981-05-15 1982-11-24 BASF Aktiengesellschaft Verfahren zur Herstellung von feinverteilten, pulverförmigen Carotinoid- bzw. Retinoidpräparaten
WO1991006292A1 (en) * 1989-11-02 1991-05-16 Danochemo A/S Process of preparing a water dispersible hydrophobic or aerophilic solid
WO2003017785A1 (en) * 2001-08-23 2003-03-06 Dsm Ip Assets B.V. Novel stabilized carotenoid compositions
US20050037115A1 (en) * 2003-08-15 2005-02-17 Linda Fullmer Carotenoid nanodispersions for use in water-based systems and a process for their preparation

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* Cited by examiner, † Cited by third party
Title
CN 101016259 A: Derwent Abstract mit AN 2008B17054 *
CN1836652A: Derwent Abstract mit AN 2007177569 *

Also Published As

Publication number Publication date
DE112010000006T5 (de) 2012-06-21
DE112010000006B4 (de) 2013-05-08
CN101549273A (zh) 2009-10-07
WO2010111912A1 (zh) 2010-10-07
CN101549273B (zh) 2011-06-15
US20120018912A1 (en) 2012-01-26
US8540908B2 (en) 2013-09-24

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