DE3673460D1 - Konversion von uracilderivaten in cytosinderivate. - Google Patents

Konversion von uracilderivaten in cytosinderivate.

Info

Publication number: DE3673460D1
Authority: DE; Germany
Prior art keywords: derivatives; conversion; cytosine; uracil; uracil derivatives
Prior art date: 1985-06-04
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Fee Related

Application number

DE8686107302T

Other languages

English (en)

Inventor

Mitsuru Kawada

Kiyoharu Matsumoto

Masaaki Tsurushima

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Takeda Pharmaceutical Co Ltd

Original Assignee

Takeda Chemical Industries Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-06-04

Filing date

1986-05-29

Publication date

1990-09-20

1986-02-05 Priority claimed from JP61024640A external-priority patent/JPS6289667A/ja

1986-05-29 Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd

1990-09-20 Application granted granted Critical

1990-09-20 Publication of DE3673460D1 publication Critical patent/DE3673460D1/de

2006-05-30 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Links

ISAKRJDGNUQOIC-UHFFFAOYSA-N Uracil Chemical class O=C1C=CNC(=O)N1 ISAKRJDGNUQOIC-UHFFFAOYSA-N 0.000 title 1
238000006243 chemical reaction Methods 0.000 title 1
OPTASPLRGRRNAP-UHFFFAOYSA-N cytosine Chemical class NC=1C=CNC(=O)N=1 OPTASPLRGRRNAP-UHFFFAOYSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Saccharide Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

DE8686107302T 1985-06-04 1986-05-29 Konversion von uracilderivaten in cytosinderivate. Expired - Fee Related DE3673460D1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP12178685		1985-06-04
JP61024640A JPS6289667A (ja)	1985-06-04	1986-02-05	４−ｏ−有機スルホニルウラシル誘導体の製造法

Publications (1)

Publication Number	Publication Date
DE3673460D1 true DE3673460D1 (de)	1990-09-20

Family

ID=26362190

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE8686107302T Expired - Fee Related DE3673460D1 (de)	1985-06-04	1986-05-29	Konversion von uracilderivaten in cytosinderivate.

Country Status (6)

Country	Link
US (1)	US4754026A (de)
EP (1)	EP0204264B1 (de)
CN (1)	CN1012367B (de)
CA (1)	CA1268174A (de)
DE (1)	DE3673460D1 (de)
ES (2)	ES8800909A1 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5215970A (en) *	1987-04-16	1993-06-01	Medivir Ab	Nucleosides and nucleotide analogues, pharmaceutical composition and processes for the preparation of the compounds
US6306647B1 (en)	1987-06-16	2001-10-23	Ajinomoto Co., Inc.	Process for producing and purifying 2′,3′-dideoxynucleosides, and process for producing 2′,3′-dideoxy-2′,3′-didehydronucleosides
US4835104A (en) *	1987-06-16	1989-05-30	Ajinomoto Co., Inc., Patent & Licensing Department	Process for producing and purifying 2',3'-dideoxynucleosides, and process for producing 2',3'-dideoxy-2',3'-didehydronucleosides
WO1994019362A1 (en) *	1993-02-23	1994-09-01	City Of Hope	4-ethoxy 5-fluoro 2'deoxyuridine
EP0630897A3 (de)	1993-06-25	1995-03-01	Bristol Myers Squibb Co	3-Hydroxy-4-hydroxymethyl-2-methylen-cyclopentyl Purine und Pyrimidine.
IT1277425B1 (it)	1995-08-03	1997-11-10	Pro Bio Sint Srl	Metodo per la preparazione della 1-b-d-arabinofuranosilcitosina
MY164523A (en) *	2000-05-23	2017-12-29	Univ Degli Studi Cagliari	Methods and compositions for treating hepatitis c virus
KR20080021797A (ko)	2000-05-26	2008-03-07	이데닉스(케이만)리미티드	플라비바이러스 및 페스티바이러스의 치료방법 및 조성물
ATE535537T1 (de) *	2001-12-28	2011-12-15	Suntory Holdings Ltd	2-o-(-d-glucopyranosyl)ascorbinsäure, verfahren zu ihrer herstellung , sowie lebensmittel und kosmetika, die diese umfassende zusammensetzungen enthalten
PL374781A1 (en) *	2002-06-28	2005-10-31	Idenix (Cayman) Limited	2'-c-methyl-3'-o-l-valine ester ribofuranosyl cytidine for treatment of flaviviridae infections
NZ537662A (en) *	2002-06-28	2007-10-26	Idenix Cayman Ltd	2'-C-methyl-3'-O-L-valine ester ribofuranosyl cytidine for treatment of flaviviridae infections
US7608600B2 (en)	2002-06-28	2009-10-27	Idenix Pharmaceuticals, Inc.	Modified 2′ and 3′-nucleoside prodrugs for treating Flaviviridae infections
HUE033832T2 (en) *	2002-11-15	2018-01-29	Idenix Pharmaceuticals Llc	2'-methyl nucleosides in combination with interferon and Flaviviridae mutation
RU2005121904A (ru) *	2002-12-12	2006-01-20	Айденикс (Кайман) Лимитед (Ky)	Способ получения 2`-разветвленных нуклеозидов
BRPI0408561A (pt) *	2003-03-20	2006-03-21	Microbiol Quimica Farmaceutica	métodos para manufatura de 2'-desoxi-59-l-nucleosìeos
US7595390B2 (en) *	2003-04-28	2009-09-29	Novartis Ag	Industrially scalable nucleoside synthesis
US20050059632A1 (en) *	2003-06-30	2005-03-17	Richard Storer	Synthesis of beta-L-2'-deoxy nucleosides
JP4516863B2 (ja) *	2005-03-11	2010-08-04	株式会社ケンウッド	音声合成装置、音声合成方法及びプログラム
EP1976382B1 (de) *	2005-12-23	2013-04-24	IDENIX Pharmaceuticals, Inc.	Verfahren zur herstellung eines synthetischen zwischenprodukts für die herstellung von verzweigten nukleosiden
CN101580528B (zh) *	2009-06-15	2013-05-22	上海兆维科技发展有限公司	一种胞苷(脱氧)及其衍生物的纯化方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE140254C (de) *
FR1452186A (fr) *	1964-09-02	1966-02-25	Merck & Co Inc	Procédé de préparation de nucléosides
US3404144A (en) *	1965-12-23	1968-10-01	Research Corp	1-beta-d-arabinofuranosyl-5-fluorocytosine compounds
JPS5010595B1 (de) *	1970-09-18	1975-04-22
DE2122991C2 (de) *	1971-05-04	1982-06-09	Schering Ag, 1000 Berlin Und 4619 Bergkamen	Verfahren zur Herstellung von Cytosin- und 6-Azacytosinnucleosiden

1986
- 1986-05-27 US US06/866,960 patent/US4754026A/en not_active Expired - Fee Related
- 1986-05-29 DE DE8686107302T patent/DE3673460D1/de not_active Expired - Fee Related
- 1986-05-29 EP EP86107302A patent/EP0204264B1/de not_active Expired - Lifetime
- 1986-06-01 CN CN86103615A patent/CN1012367B/zh not_active Expired
- 1986-06-03 ES ES555646A patent/ES8800909A1/es not_active Expired
- 1986-06-03 CA CA000510679A patent/CA1268174A/en not_active Expired - Lifetime
1987
- 1987-09-01 ES ES557707A patent/ES8801904A1/es not_active Expired

Also Published As

Publication number	Publication date
CN1012367B (zh)	1991-04-17
EP0204264A2 (de)	1986-12-10
ES8801904A1 (es)	1988-03-01
CN86103615A (zh)	1986-12-03
ES555646A0 (es)	1987-12-01
ES557707A0 (es)	1988-03-01
CA1268174A (en)	1990-04-24
EP0204264A3 (en)	1988-01-07
ES8800909A1 (es)	1987-12-01
US4754026A (en)	1988-06-28
EP0204264B1 (de)	1990-08-16

Legal Events

Date	Code	Title	Description
1991-09-12	8364	No opposition during term of opposition
1994-05-05	8339	Ceased/non-payment of the annual fee

Publication	Publication Date	Title
DE3673460D1 (de)	1990-09-20	Konversion von uracilderivaten in cytosinderivate.
DK366887D0 (da)	1987-07-14	Pyrimidinderivater
DE3687915D1 (de)	1993-04-15	Aenderung von gesichtsausdruecken in der kinematographie.
ATE44464T1 (de)	1989-07-15	Antivirale nukleoside.
DE3687397D1 (de)	1993-02-11	2-fluorarabinofuranosylpurinnukleoside.
FI863074L (fi)	1987-02-01	Farmaceutiskt aktiva substanser i granulatform med foerdroejd frigivning.
FI861822A7 (fi)	1986-11-03	Antivirala kompositioner.
DE3780581D1 (de)	1992-08-27	Antiviralen phosphonomethoxyalkylen-purin- und -pyrimidin-derivate.
DE3766958D1 (de)	1991-02-07	Isochinolin-derivate.
DK375787D0 (da)	1987-07-17	Pyrimidinderivater
DE3788385D1 (de)	1994-01-20	Pyrimidin-Derivate.
DK327985A (da)	1986-01-20	Pyrimidinderivater
FI862956L (fi)	1987-01-19	Foerbaettringar i foerbraenningsmotorer med kompressor.
FI863028A0 (fi)	1986-07-23	Avboejningskrets med en modulatorkrets i kopplingsform.
DE3675846D1 (de)	1991-01-10	Guaninderivate.
DK363987D0 (da)	1987-07-13	Pyrimidinderivater
DK346787A (da)	1988-02-13	Pyrimidinderivater
DE3588103D1 (de)	1996-05-30	5-Fluorouracil-Derivate
DE3682446D1 (de)	1991-12-19	Isochinolinderivate.
BG82461A (bg)	1993-12-24	Пиримидинови производни
FI864714A0 (fi)	1986-11-19	Karbapenemderivat substituerade i 2-staellning med en kvaternaer heterotioalkyltiogrupp.
DK434486A (da)	1987-03-12	Amidinderivater i
ATE55609T1 (de)	1990-09-15	Konversion von uracilderivaten in cytosinderivate.
DK601386D0 (da)	1986-12-12	5-phenyl-1,4,5,6-tetrahydropyrimidinderivater
DK154086A (da)	1986-04-04	Pyrimidinonderivater