DE3676429D1 - Natriumsalz von etodolsaeure und verfahren zur herstellung. - Google Patents

Natriumsalz von etodolsaeure und verfahren zur herstellung.

Info

Publication number: DE3676429D1
Authority: DE; Germany
Prior art keywords: sodium salt; producing; same; etodolic acid; acid
Prior art date: 1985-10-25
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Revoked

Application number

DE8686830304T

Other languages

English (en)

Inventor

Riccardo Casero

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Farmaka Srl

Original Assignee

Farmaka Srl

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-10-25

Filing date

1986-10-23

Publication date

1991-02-07

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11198571&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE3676429(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1986-10-23 Application filed by Farmaka Srl filed Critical Farmaka Srl

1991-02-07 Application granted granted Critical

1991-02-07 Publication of DE3676429D1 publication Critical patent/DE3676429D1/de

2006-10-24 Anticipated expiration legal-status Critical

Status Revoked legal-status Critical Current

Links

XFBVBWWRPKNWHW-UHFFFAOYSA-N etodolac Chemical compound C1COC(CC)(CC(O)=O)C2=N[C]3C(CC)=CC=CC3=C21 XFBVBWWRPKNWHW-UHFFFAOYSA-N 0.000 title abstract 2
229960005293 etodolac Drugs 0.000 title abstract 2
238000004519 manufacturing process Methods 0.000 title 1
NOJNFULGOQGBKB-UHFFFAOYSA-M sodium;3-[3-tert-butylsulfanyl-1-[[4-(6-ethoxypyridin-3-yl)phenyl]methyl]-5-[(5-methylpyridin-2-yl)methoxy]indol-2-yl]-2,2-dimethylpropanoate Chemical compound [Na+].C1=NC(OCC)=CC=C1C(C=C1)=CC=C1CN1C2=CC=C(OCC=3N=CC(C)=CC=3)C=C2C(SC(C)(C)C)=C1CC(C)(C)C([O-])=O NOJNFULGOQGBKB-UHFFFAOYSA-M 0.000 title 1
159000000000 sodium salts Chemical class 0.000 abstract 2
QTBSBXVTEAMEQO-UHFFFAOYSA-N acetic acid Substances CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Pain & Pain Management (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
Rheumatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

DE8686830304T 1985-10-25 1986-10-23 Natriumsalz von etodolsaeure und verfahren zur herstellung. Revoked DE3676429D1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IT22625/85A IT1190416B (it)	1985-10-25	1985-10-25	Sali dell'acido etodolico e procedimenti per la loro preparazione

Publications (1)

Publication Number	Publication Date
DE3676429D1 true DE3676429D1 (de)	1991-02-07

Family

ID=11198571

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE8686830304T Revoked DE3676429D1 (de)	1985-10-25	1986-10-23	Natriumsalz von etodolsaeure und verfahren zur herstellung.

Country Status (6)

Country	Link
EP (1)	EP0221032B1 (de)
JP (1)	JPS62106094A (de)
AT (1)	ATE59651T1 (de)
DE (1)	DE3676429D1 (de)
ES (1)	ES2019885B3 (de)
IT (1)	IT1190416B (de)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4076831A (en) *	1972-05-16	1978-02-28	American Home Products Corporation	Pyrano[3,4-b]-indole derivatives, pharmaceutical compositions and methods of use
US4501899A (en) *	1983-08-16	1985-02-26	American Home Products Corporation	Resolution of (+)-1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid using cholesteryl aniline
US4520203A (en) *	1983-08-16	1985-05-28	American Home Products Corporation	Resolution of (±)-1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid using cinchonine
US4515961A (en) *	1983-08-16	1985-05-07	American Home Products Corporation	Resolution of (±)-1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4,-b] indole-1-acetic acid using enrichment crystallization
US4544757A (en) *	1984-02-16	1985-10-01	American Home Products Corporation	Process for the resolution of pyrano[3,4-b]indole-1-acetic acids

1985
- 1985-10-25 IT IT22625/85A patent/IT1190416B/it active
1986
- 1986-10-20 JP JP61249398A patent/JPS62106094A/ja active Pending
- 1986-10-23 AT AT86830304T patent/ATE59651T1/de not_active IP Right Cessation
- 1986-10-23 ES ES86830304T patent/ES2019885B3/es not_active Expired - Lifetime
- 1986-10-23 DE DE8686830304T patent/DE3676429D1/de not_active Revoked
- 1986-10-23 EP EP86830304A patent/EP0221032B1/de not_active Expired - Lifetime

Also Published As

Publication number	Publication date
EP0221032A3 (en)	1988-10-05
IT1190416B (it)	1988-02-16
ES2019885B3 (es)	1991-07-16
EP0221032A2 (de)	1987-05-06
ATE59651T1 (de)	1991-01-15
IT8522625A0 (it)	1985-10-25
JPS62106094A (ja)	1987-05-16
EP0221032B1 (de)	1991-01-02

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Legal Events

Date	Code	Title	Description
1992-01-09	8363	Opposition against the patent
1995-01-05	8331	Complete revocation