DE3876124T2 - Immunoassay fuer thrombomodulin. - Google Patents

Immunoassay fuer thrombomodulin.

Info

Publication number
DE3876124T2
DE3876124T2 DE19883876124 DE3876124T DE3876124T2 DE 3876124 T2 DE3876124 T2 DE 3876124T2 DE 19883876124 DE19883876124 DE 19883876124 DE 3876124 T DE3876124 T DE 3876124T DE 3876124 T2 DE3876124 T2 DE 3876124T2
Authority
DE
Germany
Prior art keywords
thrombomodulin
antibody
human thrombomodulin
binding
thrombin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE19883876124
Other languages
German (de)
English (en)
Other versions
DE3876124D1 (en
Inventor
Hidemi Ishii
Mutsuyoshi Kazama
Masahiko Nakano
Jiro Tsubouchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Gas Chemical Co Inc
Original Assignee
Mitsubishi Gas Chemical Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsubishi Gas Chemical Co Inc filed Critical Mitsubishi Gas Chemical Co Inc
Publication of DE3876124D1 publication Critical patent/DE3876124D1/de
Application granted granted Critical
Publication of DE3876124T2 publication Critical patent/DE3876124T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/745—Assays involving non-enzymic blood coagulation factors
    • G01N2333/7452—Thrombomodulin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
DE19883876124 1987-04-01 1988-03-29 Immunoassay fuer thrombomodulin. Expired - Fee Related DE3876124T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP7750787 1987-04-01

Publications (2)

Publication Number Publication Date
DE3876124D1 DE3876124D1 (en) 1993-01-07
DE3876124T2 true DE3876124T2 (de) 1993-05-06

Family

ID=13635877

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19883876124 Expired - Fee Related DE3876124T2 (de) 1987-04-01 1988-03-29 Immunoassay fuer thrombomodulin.

Country Status (3)

Country Link
EP (1) EP0285511B1 (2)
JP (1) JPS6447391A (2)
DE (1) DE3876124T2 (2)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6445398A (en) * 1987-08-13 1989-02-17 Kowa Co Antithrombin-binding substance monoclonal antibody, hybridoma producing said antibody and method for purifying and measuring thrombin-binding substance utilizing said monoclonal antibody
AU635355B2 (en) * 1989-11-02 1993-03-18 Teijin Limited Immunoassay of human thrombomodulin, and reagent and kit therefor
JP2509001B2 (ja) * 1989-11-02 1996-06-19 帝人株式会社 ヒト・トロンボモジユリンの免疫学的測定方法、そのための試薬及びそのためのキツト
JPH0736019B2 (ja) * 1989-12-27 1995-04-19 富士薬品工業株式会社 新規な抗ヒトトロンボモジュリンモノクローナル抗体によるヒトトロンボモジュリンおよびその分解産物の定量方法
EP0949507A4 (en) * 1996-12-26 2000-03-22 Fuji Yakuhin Kogyo Kk AGENTS FOR TREATING URINE SAMPLES
AU2227201A (en) * 1999-12-28 2001-07-09 Fuji Chemical Industries, Ltd. Method of judging the possibility of abortion/premature birth and reagent therefor
RU2433829C2 (ru) 2006-10-06 2011-11-20 Асахи Касеи Фарма Корпорейшн Средство для лечения и/или улучшения состояния при диссеминированном внутрисосудистом свертывании
DK2781221T3 (da) 2011-11-15 2020-06-02 Asahi Kasei Pharma Corp Medicin til behandling og/eller forbedring af sepsis
PL2857037T3 (pl) 2012-05-31 2019-12-31 Kinki University Środek do leczenia profilaktycznego i/lub terapeutycznego obwodowego bólu neuropatycznego wywoływanego przez środek przeciwnowotworowy
WO2020067389A1 (ja) 2018-09-28 2020-04-02 旭化成ファーマ株式会社 抗悪性腫瘍剤による末梢神経障害の症状軽減及び／又は発症抑制のための医薬
EP3871684B1 (en) 2018-10-22 2024-06-26 Asahi Kasei Pharma Corporation Drug for treating and/or improving septicemia associated with coagulation abnormality

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1987000050A1 (fr) * 1985-06-28 1987-01-15 Asahi Kasei Kogyo Kabushiki Kaisha Nouvelle substance physiologiquement active limitant la coagulation du sang
EP0253331B1 (en) * 1986-07-15 1994-10-19 Kowa Co. Ltd. Thrombin-binding substance and process for its preparation

Also Published As

Publication number Publication date
DE3876124D1 (en) 1993-01-07
JPH0542920B2 (2) 1993-06-30
EP0285511A3 (en) 1988-12-28
JPS6447391A (en) 1989-02-21
EP0285511A2 (en) 1988-10-05
EP0285511B1 (en) 1992-11-25

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee