DE602006012425D1 - Verfahren zur herstellung einer voll entwickelten natürlichen killerzelle - Google Patents

Verfahren zur herstellung einer voll entwickelten natürlichen killerzelle

Info

Publication number
DE602006012425D1
DE602006012425D1 DE602006012425T DE602006012425T DE602006012425D1 DE 602006012425 D1 DE602006012425 D1 DE 602006012425D1 DE 602006012425 T DE602006012425 T DE 602006012425T DE 602006012425 T DE602006012425 T DE 602006012425T DE 602006012425 D1 DE602006012425 D1 DE 602006012425D1
Authority
DE
Germany
Prior art keywords
natural killer
killer cell
axl
protein
precursor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602006012425T
Other languages
English (en)
Inventor
Hyung Sik Kang
Sang Hyun Kim
Eun Mi Kim
Eun Hee Lee
Hee Jung Yun
Chang Bo Ko
Young Jin Heo
Woo Young Shim
Seong Beom Heo
Ji Yeon Yoon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GOOD CELL LIFE Inc
Industry Foundation of Chonnam National University
Original Assignee
GOOD CELL LIFE Inc
Industry Foundation of Chonnam National University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GOOD CELL LIFE Inc, Industry Foundation of Chonnam National University filed Critical GOOD CELL LIFE Inc
Priority claimed from PCT/KR2006/003627 external-priority patent/WO2007032634A1/en
Publication of DE602006012425D1 publication Critical patent/DE602006012425D1/de
Anticipated expiration legal-status Critical
Active legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0646—Natural killers cells [NK], NKT cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/125—Stem cell factor [SCF], c-kit ligand [KL]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]
    • C12N2501/2307—Interleukin-7 (IL-7)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/26—Flt-3 ligand (CD135L, flk-2 ligand)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/70—Enzymes
    • C12N2501/72—Transferases [EC 2.]
    • C12N2501/727—Kinases (EC 2.7.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/11—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from blood or immune system cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Developmental Biology & Embryology (AREA)
  • General Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Virology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE602006012425T 2005-09-12 2006-09-12 Verfahren zur herstellung einer voll entwickelten natürlichen killerzelle Active DE602006012425D1 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
KR1020050084897 2005-09-12
KR1020050084898 2005-09-12
KR1020050084896 2005-09-12
KR1020060070390A KR100650384B1 (ko) 2005-09-12 2006-07-26 성숙자연살해세포의 분화용 조성물 및 그 제조 방법
PCT/KR2006/003627 WO2007032634A1 (en) 2005-09-12 2006-09-12 A method for production of mature natural killer cell

Publications (1)

Publication Number Publication Date
DE602006012425D1 true DE602006012425D1 (de) 2010-04-08

Family

ID=37713748

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602006012425T Active DE602006012425D1 (de) 2005-09-12 2006-09-12 Verfahren zur herstellung einer voll entwickelten natürlichen killerzelle

Country Status (4)

Country Link
JP (1) JP2009507827A (de)
KR (1) KR100650384B1 (de)
AT (1) ATE458808T1 (de)
DE (1) DE602006012425D1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009104911A2 (en) * 2008-02-22 2009-08-27 Industry Foundation Of Chonnam National University Uses as agents for prophylaxis or treatment of cervical cancer
WO2012175691A1 (en) * 2011-06-22 2012-12-27 INSERM (Institut National de la Santé et de la Recherche Médicale) Anti-axl antibodies and uses thereof
DE102011106914B4 (de) 2011-07-08 2015-08-27 Zellwerk Gmbh Mäander- Bioreaktor und Verfahren zu dynamischen Expansion, Differenzierung und Ernte von hämatopoetischen Zellen
EP3737743A1 (de) * 2018-01-08 2020-11-18 Iovance Biotherapeutics, Inc. Verfahren zur erzeugung von til-produkten, die für tumorantigenspezifische t-zellen angereichert sind
US11713446B2 (en) 2018-01-08 2023-08-01 Iovance Biotherapeutics, Inc. Processes for generating TIL products enriched for tumor antigen-specific T-cells
CN113227357A (zh) * 2018-10-01 2021-08-06 根特大学 人造血干细胞向具有增强的抗体依赖性细胞毒性活性的成熟自然杀伤细胞的加速的分化
CN114736859B (zh) * 2022-06-13 2022-08-19 广东先康达生物科技有限公司 一种脐带血nk细胞的培养液及培养方法

Also Published As

Publication number Publication date
JP2009507827A (ja) 2009-02-26
KR100650384B1 (ko) 2006-11-30
ATE458808T1 (de) 2010-03-15

Similar Documents

Publication Publication Date Title
GB2441718A (en) Differentiation of primate pluripotent stem cells to cardiomyocyte-lineage cells
WO2007149182A3 (en) Differentiation and enrichment of islet-like cells from human pluripotent stem cells
ATE464799T1 (de) Herstellungsverfahren für eine stange zur herstellung eines raucherartikels
MY162929A (en) Apparatus and methods for controlling cellular development
NZ587023A (en) Composition comprising protein and disperse fat
ATE485064T1 (de) Zusammensetzung und gerät zur knochenwiederherstellung
WO2006017134A3 (en) Preprimitive streak and mesendoderm cells
GB2453074A (en) Differentiation of primate pluripotent cells to hepatocyte-lineage cells
SG10201803982TA (en) Antibodies and processes for preparing the same
EP1679964A4 (de) Zusammensetzungen mit bzw. verfahren zur verwendung von sirna-amphipathischen verbindungen und polykationen
WO2011099783A3 (ko) 지방조직 유래 줄기세포 및 단핵구로부터 세포성장인자의 생산방법 및 그 이용
ATE414760T1 (de) Verfahren zur herstellung einer epithelzellen enthaltenden zellzusammensetzung
ATE458808T1 (de) Verfahren zur herstellung einer voll entwickelten natürlichen killerzelle
EP1687413A4 (de) Verfahren zur differenzierung einer mesenchym-stammzelle zu einer nervenzelle sowie die nervenzelle enthaltende pharmazeutische zusammensetzung gegen eine neurodegenerative krankheit
DE602005023592D1 (de) Endothelvorläuferzellen und verfahren zur verwendung davon
EP2341147A3 (de) Präprimitivstreifen und mesendoderm- Zellen
WO2011112976A3 (en) Methods for regenerating skeletal muscle
WO2008111506A1 (ja) 遺伝子導入細胞調製方法
EP1637590A4 (de) Differenzierte zellen mit ursprung in vorläuferfettzellen sowie verfahren zur gewinnung davon
CN102627055A (zh) 一种制作黑白剪贴剪纸艺术品的方法
CN204443497U (zh) 石斛育种瓶
CN205165878U (zh) 一种不锈钢细化片
AU2004230971B2 (en) Method of growing sperm stem cells in vitro, sperm stem cells grown by the method, and medium additive kit to be used in growing sperm stem cells in vitro
DE602004006330D1 (de) Verfahren zur Herstellung eines cysteinhaltigen Lebensmittels
CN201782924U (zh) 一种清香骨灰盒

Legal Events

Date Code Title Description
8364 No opposition during term of opposition