DEP0017642DA - Process for the production of acid- or salt-free invert sugar solutions - Google Patents

Process for the production of acid- or salt-free invert sugar solutions

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Publication number
DEP0017642DA
DEP0017642DA DEP0017642DA DE P0017642D A DEP0017642D A DE P0017642DA DE P0017642D A DEP0017642D A DE P0017642DA
Authority
DE
Germany
Prior art keywords
acid
invert sugar
salt
production
sugar solutions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
Other languages
German (de)
Inventor
Werner Dipl.-Chem. Dr. Dortmund Lange
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Publication date

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Description

Für therapeutische Zwecke, insbesondere als intravenöse Injektionen, findet Traubenzucker und dessen Lösungen Verwendung. Durch Säurebehandlung verschiedener Rohrzuckerarten erhaltener Invertzucker konnte hierfür wegen der von der Herstellung herrührenden Säure, auch nach der Neutralisierung infolge der vorhandenen Salzmenge, keine Anwendung finden. Es ist nun gefunden worden, dass dieses gelingt und dass Invertzucker an Stelle von Traubenzucker benutzt werden kann, wenn man den Säure- oder Salzgehalt mit Hilfe der Dialyse entfernt. Die Flüssigkeit wird zu diesem Zwecke einer Dialyse gegen Wasser unterworfen, bis alle vorhandene Säure bzw. Salze in das wässerige Medium übergegangen sind.Dextrose and its solutions are used for therapeutic purposes, in particular as intravenous injections. Invert sugar obtained by acid treatment of various types of cane sugar could not be used for this because of the acid resulting from the production, even after neutralization due to the amount of salt present. It has now been found that this works and that invert sugar can be used in place of grape sugar if the acid or salt content is removed with the help of dialysis. For this purpose, the liquid is subjected to dialysis against water until all the acids or salts present have passed into the aqueous medium.

Als geeignete Diaphragmen kommen in Betracht tierische Häute, Häute aus Kunststoffen, künstliche Häute aus Leder- oder Hautabfällen, feste Röhren oder Platten aus halbdurchlässigem Ton, der mit einer geeigneten Schicht aus Gelatine o. dgl. überzogen sein kann u. dgl. m. Auf diese Weise ist es möglich, völlig salz- und säurefreie Invertzuckerlösungen für pharmazeutische und diätetische Zwecke herzustellen.Suitable diaphragms are animal skins, skins made of plastics, artificial skins made of leather or skin waste, solid tubes or plates made of semi-permeable clay, which can be coated with a suitable layer of gelatin or the like, and the like In this way it is possible to produce completely salt and acid-free invert sugar solutions for pharmaceutical and dietetic purposes.

Zur Ausführung der Erfindung werden z. B. 100 l einer in bekannter Weise mit konzentrierter Ameisensäure hergestellten Invertzuckerlösung in einem aus tierischem Darm hergestellten Diaphragma gegen Wasser dialysiert, bis im wässerigen Medium keine Ameisensäure mehr nachweisbar ist. Die dialysierte Lösung wird nach einem der bekannten Ver- fahren auf Invertzucker weiterverarbeitet oder findet sterilisiert zur intravenösen Injektion Verwendung.To carry out the invention, for. B. 100 l of an invert sugar solution prepared in a known manner with concentrated formic acid in a diaphragm made from animal intestine dialyzed against water until formic acid is no longer detectable in the aqueous medium. The dialyzed solution is according to one of the known methods processed on invert sugar or sterilized for intravenous injection.

Claims (1)

Verfahren zur Herstellung säure- bzw. salzfreier Invertzuckerlösungen, dadurch gekennzeichnet, dass eine durch Säurebehandlung erhaltene Invertzuckerlösung, gegebenenfalls nach der Neutralisierung, durch Dialyse gegen Wasser von ihrem Gehalt an Säure bzw. Salz befreit wird.Process for the production of acid- or salt-free invert sugar solutions, characterized in that an invert sugar solution obtained by acid treatment is freed of its acid or salt content by dialysis against water, if necessary after neutralization.

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