DK0410953T3 - Piperidinforbindelser - Google Patents

Piperidinforbindelser

Info

Publication number: DK0410953T3
Authority: DK; Denmark
Prior art keywords: carbon atoms; optionally substituted; radicals; piperidine; alkaryl
Prior art date: 1989-07-27

Application number

DK90870119.6T

Other languages

English (en)

Inventor

Daniel Paul Getman

Crescenzo Gary Anthony De

Original Assignee

Monsanto Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-07-27

Filing date

1990-07-23

Publication date

1996-01-22

1989-07-27 Priority claimed from US07/386,538 external-priority patent/US5025021A/en

1989-08-29 Priority claimed from US07/400,252 external-priority patent/US5026713A/en

1990-07-23 Application filed by Monsanto Co filed Critical Monsanto Co

1996-01-22 Application granted granted Critical

1996-01-22 Publication of DK0410953T3 publication Critical patent/DK0410953T3/da

Links

NQRYJNQNLNOLGT-UHFFFAOYSA-N Piperidine Chemical compound C1CCNCC1 NQRYJNQNLNOLGT-UHFFFAOYSA-N 0.000 title 2
125000004432 carbon atom Chemical group C* 0.000 abstract 4
102000005744 Glycoside Hydrolases Human genes 0.000 abstract 1
108010031186 Glycoside Hydrolases Proteins 0.000 abstract 1
125000002252 acyl group Chemical group 0.000 abstract 1
125000002877 alkyl aryl group Chemical group 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
230000005764 inhibitory process Effects 0.000 abstract 1
125000003107 substituted aryl group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/42—Oxygen atoms attached in position 3 or 5
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/14—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/22—Tin compounds
- C07F7/2224—Compounds having one or more tin-oxygen linkages

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Diabetes (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Hematology (AREA)
Obesity (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Endocrinology (AREA)
Emergency Medicine (AREA)
Hydrogenated Pyridines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

DK90870119.6T 1989-07-27 1990-07-23 Piperidinforbindelser DK0410953T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US07/386,538 US5025021A (en)	1989-07-27	1989-07-27	1,2-dideoxy-2-fluoronojirimycin as glycosidase inhibitors
US07/400,252 US5026713A (en)	1989-08-29	1989-08-29	1,3-dideoxy-3-fluoronojirimycin which inhibits glycosidase activity

Publications (1)

Publication Number	Publication Date
DK0410953T3 true DK0410953T3 (da)	1996-01-22

Family

ID=27011478

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK90870119.6T DK0410953T3 (da)	1989-07-27	1990-07-23	Piperidinforbindelser

Country Status (8)

Country	Link
EP (1)	EP0410953B1 (da)
JP (1)	JPH0358969A (da)
AT (1)	ATE129997T1 (da)
CA (1)	CA2022061A1 (da)
DE (1)	DE69023408T2 (da)
DK (1)	DK0410953T3 (da)
ES (1)	ES2036512T3 (da)
GR (1)	GR3018629T3 (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5128347A (en) *	1990-10-18	1992-07-07	Monsanto Company	Glycosidase inhibiting 1,4-dideoxy-4-fluoronojirimycin
EP0566557B1 (en) *	1992-04-01	1996-09-04	G.D. SEARLE & COMPANY	2- and 3- amino and azido derivatives of 1,5-iminosugars as antiviral compounds
US5258518A (en) *	1992-04-01	1993-11-02	G. D. Searle & Co.	2-substituted tertiary carbinol derivatives of deoxynojirimycin
US5268482A (en) *	1992-04-01	1993-12-07	G. D. Searle & Co.	2- and 3-sulfur derivatives of 1,5-iminosugars
US5451679A (en) *	1994-03-08	1995-09-19	G. D. Searle & Co.	2-chloro and 2-bromo derivatives of 1,5-iminosugars
JPH10502093A (ja) *	1994-07-27	1998-02-24	ジェンザイム・リミテッド	レジオ選択的硫酸化

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3611841A1 (de) *	1986-04-09	1987-10-15	Bayer Ag	Verfahren zur herstellung von 1-desoxynojirimycin und dessen n-derivaten
DE3722788A1 (de) *	1987-07-10	1989-01-19	Bayer Ag	Chirale 6-hydroxymethylenverzweigte 3-amino-4,5-dihydroxypiperidine, zwischenprodukte zu ihrer herstellung, verfahren zu ihrer herstellung und ihre verwendung

1990
- 1990-07-23 ES ES90870119T patent/ES2036512T3/es not_active Expired - Lifetime
- 1990-07-23 AT AT90870119T patent/ATE129997T1/de not_active IP Right Cessation
- 1990-07-23 DK DK90870119.6T patent/DK0410953T3/da active
- 1990-07-23 DE DE69023408T patent/DE69023408T2/de not_active Expired - Fee Related
- 1990-07-23 EP EP90870119A patent/EP0410953B1/en not_active Expired - Lifetime
- 1990-07-26 JP JP2198981A patent/JPH0358969A/ja active Pending
- 1990-07-26 CA CA002022061A patent/CA2022061A1/en not_active Abandoned
1996
- 1996-01-09 GR GR960400049T patent/GR3018629T3/el unknown

Also Published As

Publication number	Publication date
EP0410953A3 (en)	1991-08-21
DE69023408D1 (de)	1995-12-14
EP0410953B1 (en)	1995-11-08
ES2036512T1 (es)	1993-06-01
GR3018629T3 (en)	1996-04-30
ES2036512T3 (es)	1996-03-01
ATE129997T1 (de)	1995-11-15
JPH0358969A (ja)	1991-03-14
CA2022061A1 (en)	1991-01-28
EP0410953A2 (en)	1991-01-30
DE69023408T2 (de)	1996-05-02

Publication	Publication Date	Title
DE69020287D1 (de)	1995-07-27	Pleuromutiline.
ATE90358T1 (de)	1993-06-15	Zwischenprodukte in der synthese von diaminandrostan-derivaten.
DK0826688T3 (da)	2001-10-22	Pentacykliske forbindelser
DK345989D0 (da)	1989-07-12	Quinolinderivater
DE69728544D1 (de)	2004-05-13	Totalsynthese von acylfulvenen mit antitumorwirkung
FI952101A0 (fi)	1995-05-03	Merkaptanfoerening
DE69104593D1 (de)	1994-11-17	Herstellung und Verwendung von N-Jodopropargyl-oxycarbonylaminosäure-Estern als antimicrobielle Mittel.
ATE93232T1 (de)	1993-09-15	Bis(methylendioxy)biphenyl-verbindungen.
DE69001495D1 (de)	1993-06-09	Dioxaphosphorin-verbindungen und damit stabilisierte polyolefin-zusammensetzungen.
ATE129997T1 (de)	1995-11-15	Glykosidasehemmende piperidinverbindungen.
FI914526A0 (fi)	1991-09-26	Foerening, dess framstaellning och anvaendning.
ES2005192A6 (es)	1989-03-01	Procedimiento para la fabricacion de un derivado de 1,5-diofenil-ih-1,2,4-triazol-3-carboxamida.
FI914525A0 (fi)	1991-09-26	Foerening, anvaendning och framstaellning.
DE3879058D1 (de)	1993-04-15	4-piperidincarboxamid-derivate.
DE3664467D1 (de)	1989-08-24	Pineapple ketone l'alkoxyalkyl derivatives
ES469096A1 (es)	1978-11-16	Un procedimiento para la preparacion dos sustancialmente insolubles en agua.
ATE189813T1 (de)	2000-03-15	Prostaglandin-i-analoga
ATE100449T1 (de)	1994-02-15	1,3-dioxolan-benzoesaeure und derivate davon.