DK0415263T3 - Stabilisering af perfluorcarbon-emulsioner samt perforerede heterocykliske forbindelser anvendelige som emulsionsstabiliserende additiver - Google Patents

Stabilisering af perfluorcarbon-emulsioner samt perforerede heterocykliske forbindelser anvendelige som emulsionsstabiliserende additiver

Info

Publication number
DK0415263T3
DK0415263T3 DK90116139.8T DK90116139T DK0415263T3 DK 0415263 T3 DK0415263 T3 DK 0415263T3 DK 90116139 T DK90116139 T DK 90116139T DK 0415263 T3 DK0415263 T3 DK 0415263T3
Authority
DK
Denmark
Prior art keywords
group
heterocyclic compounds
perforated
stabilization
stabilizing additives
Prior art date
Application number
DK90116139.8T
Other languages
English (en)
Inventor
Hasso Meinert
Juergen Mader
Rudolf Fackler
Peter Reuter
Wolfgang Roehlke
Monika Gennies
Joachim Baer
Original Assignee
Kali Chemie Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kali Chemie Ag filed Critical Kali Chemie Ag
Application granted granted Critical
Publication of DK0415263T3 publication Critical patent/DK0415263T3/da

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0026Blood substitute; Oxygen transporting formulations; Plasma extender
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/38Halogen atoms or nitro radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D265/00Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/281,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/301,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C25ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25BELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
    • C25B3/00Electrolytic production of organic compounds
    • C25B3/01Products
    • C25B3/05Heterocyclic compounds
    • CCHEMISTRY; METALLURGY
    • C25ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25BELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
    • C25B3/00Electrolytic production of organic compounds
    • C25B3/01Products
    • C25B3/07Oxygen containing compounds
    • CCHEMISTRY; METALLURGY
    • C25ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25BELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
    • C25B3/00Electrolytic production of organic compounds
    • C25B3/01Products
    • C25B3/09Nitrogen containing compounds
    • CCHEMISTRY; METALLURGY
    • C25ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25BELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
    • C25B3/00Electrolytic production of organic compounds
    • C25B3/01Products
    • C25B3/11Halogen containing compounds
    • CCHEMISTRY; METALLURGY
    • C25ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25BELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
    • C25B3/00Electrolytic production of organic compounds
    • C25B3/20Processes
    • C25B3/27Halogenation
    • C25B3/28Fluorination

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Metallurgy (AREA)
  • Materials Engineering (AREA)
  • Electrochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Colloid Chemistry (AREA)
  • Pyrrole Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK90116139.8T 1989-08-30 1990-08-23 Stabilisering af perfluorcarbon-emulsioner samt perforerede heterocykliske forbindelser anvendelige som emulsionsstabiliserende additiver DK0415263T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3928692 1989-08-30
DE3941514 1989-12-15

Publications (1)

Publication Number Publication Date
DK0415263T3 true DK0415263T3 (da) 1994-07-04

Family

ID=25884569

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90116139.8T DK0415263T3 (da) 1989-08-30 1990-08-23 Stabilisering af perfluorcarbon-emulsioner samt perforerede heterocykliske forbindelser anvendelige som emulsionsstabiliserende additiver

Country Status (7)

Country Link
US (1) US5120731A (da)
EP (1) EP0415263B1 (da)
JP (1) JP3029277B2 (da)
AT (1) ATE107293T1 (da)
DE (2) DE4019062A1 (da)
DK (1) DK0415263T3 (da)
ES (1) ES2055248T3 (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4100059C2 (de) * 1991-01-03 1994-08-25 Adatomed Pharma & Med Behandlungsflüssigkeit zum Wiederanlegen (Entfalten) abgelöster Netzhaut an die Aderhaut des Auges
US5264220A (en) * 1991-11-12 1993-11-23 Long David M Jr Method of extending the vascular dwell-time of particulate therapeutic and particulate diagnostic agents
US5628930A (en) * 1992-10-27 1997-05-13 Alliance Pharmaceutical Corp. Stabilization of fluorocarbon emulsions
US5635538A (en) * 1993-03-16 1997-06-03 Alliance Pharmaceutical Corp. Fluorocarbon emulsions with reduced pulmonary gas-trapping properties
CH686134A5 (de) * 1994-05-10 1996-01-15 Lonza Ag Gampel Wallis Geschof Tertiores Diamin, Verwendung als Katalysator und Verfahren zur Herstellung von tertioren Diaminen.
NZ508013A (en) * 1998-05-07 2003-08-29 Corixa Corp Adjuvant composition for use with an antigen in a vaccine composition
US6235796B1 (en) * 2000-06-26 2001-05-22 Sarfaraz K. Niazi Use of fluorocarbons for the prevention of surgical adhesions
RU2259819C1 (ru) * 2004-03-01 2005-09-10 Кузнецова Ирина Николаевна Эмульсия перфторорганических соединений медицинского назначения и способ её получения
WO2013043236A1 (en) * 2011-09-22 2013-03-28 Rockland Technimed, Ltd. Compositions and methods useful for realtime in situ physiological molecular imaging of oxygen metabolism

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3956293A (en) * 1968-02-08 1976-05-11 Minnesota Mining And Manufacturing Company Tri (fluoroaliphatic) alpha fluosulfato amines and derivatives thereof
DE3277769D1 (en) * 1981-09-08 1988-01-14 Green Cross Corp Perfluorochemicals, process for preparing the same and their use as blood substitutes
US4530926A (en) * 1982-06-29 1985-07-23 The Green Cross Corporation Perfluorotricyclic amines as oxygen carriers
US4766261A (en) * 1984-09-17 1988-08-23 Adamantech, Inc. Purification of fluorocarbons
GB8504916D0 (en) * 1985-02-26 1985-03-27 Isc Chemicals Ltd Emulsions of perfluorocarbons in aqueous media

Also Published As

Publication number Publication date
DE4019062A1 (de) 1991-03-07
JP3029277B2 (ja) 2000-04-04
JPH0393721A (ja) 1991-04-18
ATE107293T1 (de) 1994-07-15
ES2055248T3 (es) 1994-08-16
EP0415263A3 (en) 1991-05-02
EP0415263A2 (de) 1991-03-06
US5120731A (en) 1992-06-09
EP0415263B1 (de) 1994-06-15
DE59006123D1 (de) 1994-07-21

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