DK0420464T3 - 3-isoxazolonderivater, deres fremstilling af deres terapeutiske anvendelser - Google Patents
3-isoxazolonderivater, deres fremstilling af deres terapeutiske anvendelserInfo
- Publication number
- DK0420464T3 DK0420464T3 DK90310125.1T DK90310125T DK0420464T3 DK 0420464 T3 DK0420464 T3 DK 0420464T3 DK 90310125 T DK90310125 T DK 90310125T DK 0420464 T3 DK0420464 T3 DK 0420464T3
- Authority
- DK
- Denmark
- Prior art keywords
- optionally substituted
- alkyl
- substituted phenyl
- preparation
- hydrogen
- Prior art date
Links
- FUOSTELFLYZQCW-UHFFFAOYSA-N 1,2-oxazol-3-one Chemical class OC=1C=CON=1 FUOSTELFLYZQCW-UHFFFAOYSA-N 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 3
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 2
- 150000002431 hydrogen Chemical class 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 125000002723 alicyclic group Chemical group 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 125000000051 benzyloxy group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])O* 0.000 abstract 1
- 208000026106 cerebrovascular disease Diseases 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 125000001183 hydrocarbyl group Chemical group 0.000 abstract 1
- 125000000842 isoxazolyl group Chemical group 0.000 abstract 1
- 239000003158 myorelaxant agent Substances 0.000 abstract 1
- 125000000951 phenoxy group Chemical group [H]C1=C([H])C([H])=C(O*)C([H])=C1[H] 0.000 abstract 1
- 125000006413 ring segment Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
- C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
- C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D261/12—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP24970089 | 1989-09-26 | ||
| JP9697690 | 1990-04-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0420464T3 true DK0420464T3 (da) | 1994-11-07 |
Family
ID=26438116
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK90310125.1T DK0420464T3 (da) | 1989-09-26 | 1990-09-17 | 3-isoxazolonderivater, deres fremstilling af deres terapeutiske anvendelser |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0420464B1 (da) |
| KR (1) | KR910006251A (da) |
| AT (1) | ATE108444T1 (da) |
| CA (1) | CA2026177A1 (da) |
| DE (1) | DE69010606T2 (da) |
| DK (1) | DK0420464T3 (da) |
| ES (1) | ES2060056T3 (da) |
| IE (1) | IE69020B1 (da) |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE60267B1 (en) * | 1986-12-26 | 1994-06-29 | Sankyo Co | Centrally-acting muscle relaxants |
-
1990
- 1990-09-17 AT AT90310125T patent/ATE108444T1/de not_active IP Right Cessation
- 1990-09-17 ES ES90310125T patent/ES2060056T3/es not_active Expired - Lifetime
- 1990-09-17 EP EP90310125A patent/EP0420464B1/en not_active Expired - Lifetime
- 1990-09-17 DK DK90310125.1T patent/DK0420464T3/da active
- 1990-09-17 DE DE69010606T patent/DE69010606T2/de not_active Expired - Fee Related
- 1990-09-25 IE IE344590A patent/IE69020B1/en not_active IP Right Cessation
- 1990-09-25 CA CA002026177A patent/CA2026177A1/en not_active Abandoned
- 1990-09-26 KR KR1019900015314A patent/KR910006251A/ko not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| KR910006251A (ko) | 1991-04-29 |
| CA2026177A1 (en) | 1991-03-27 |
| DE69010606T2 (de) | 1995-03-23 |
| EP0420464A2 (en) | 1991-04-03 |
| DE69010606D1 (de) | 1994-08-18 |
| ATE108444T1 (de) | 1994-07-15 |
| IE69020B1 (en) | 1996-07-24 |
| EP0420464A3 (en) | 1991-07-17 |
| IE903445A1 (en) | 1991-04-10 |
| EP0420464B1 (en) | 1994-07-13 |
| ES2060056T3 (es) | 1994-11-16 |
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