DK0422762T3 - Fremgangsmåde til at bedømme følsomheden af HIV-1 over for zidovudin og oligonukleotider dertil - Google Patents

Fremgangsmåde til at bedømme følsomheden af HIV-1 over for zidovudin og oligonukleotider dertil

Info

Publication number: DK0422762T3
Authority: DK; Denmark
Prior art keywords: zidovudine; hiv; oligonucleotides; assessing; sensitivity
Prior art date: 1989-08-09

Application number

DK90308721.1T

Other languages

Danish (da)

English (en)

Inventor

Brendan Alexander Larder

Sharon Dawn Symons

Original Assignee

Wellcome Found

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-08-09

Filing date

1990-08-08

Publication date

1995-07-24

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10661415&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0422762(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1990-08-08 Application filed by Wellcome Found filed Critical Wellcome Found

1995-07-24 Application granted granted Critical

1995-07-24 Publication of DK0422762T3 publication Critical patent/DK0422762T3/da

Links

241000713772 Human immunodeficiency virus 1 Species 0.000 title 1
108091034117 Oligonucleotide Proteins 0.000 title 1
JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 title 1
230000035945 sensitivity Effects 0.000 title 1
HBOMLICNUCNMMY-XLPZGREQSA-N zidovudine Chemical compound O=C1NC(=O)C(C)=CN1[C@@H]1O[C@H](CO)[C@@H](N=[N+]=[N-])C1 HBOMLICNUCNMMY-XLPZGREQSA-N 0.000 title 1
229960002555 zidovudine Drugs 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
- C12Q1/702—Specific hybridization probes for retroviruses
- C12Q1/703—Viruses associated with AIDS
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16211—Human Immunodeficiency Virus, HIV concerning HIV gagpol
- C12N2740/16222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/974—Aids related test

Landscapes

Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Wood Science & Technology (AREA)
Virology (AREA)
Zoology (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Immunology (AREA)
Microbiology (AREA)
Biotechnology (AREA)
Analytical Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
General Engineering & Computer Science (AREA)
Physics & Mathematics (AREA)
AIDS & HIV (AREA)
Gastroenterology & Hepatology (AREA)
Medicinal Chemistry (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Saccharide Compounds (AREA)

DK90308721.1T 1989-08-09 1990-08-08 Fremgangsmåde til at bedømme følsomheden af HIV-1 over for zidovudin og oligonukleotider dertil DK0422762T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB898918226A GB8918226D0 (en)	1989-08-09	1989-08-09	Dna assays

Publications (1)

Publication Number	Publication Date
DK0422762T3 true DK0422762T3 (da)	1995-07-24

Family

ID=10661415

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK90308721.1T DK0422762T3 (da)	1989-08-09	1990-08-08	Fremgangsmåde til at bedømme følsomheden af HIV-1 over for zidovudin og oligonukleotider dertil

Country Status (12)

Country	Link
US (2)	US5409810A (de)
EP (1)	EP0422762B1 (de)
JP (1)	JP3105907B2 (de)
AU (1)	AU638475B2 (de)
CA (1)	CA2022942C (de)
DE (1)	DE69019795T2 (de)
DK (1)	DK0422762T3 (de)
ES (1)	ES2072983T3 (de)
GB (1)	GB8918226D0 (de)
IE (1)	IE69846B1 (de)
NZ (1)	NZ234812A (de)
ZA (1)	ZA906263B (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
USRE39282E1 (en) *	1989-08-09	2006-09-12	Smithkline Beecham Corporation	Nucleic acid derivatives
CA2042093C (en) *	1990-05-09	2002-12-24	Gyula Hadlaczky	Cell line carrying an excess of mammalian centromeres
WO1992016180A2 (en) *	1991-03-13	1992-10-01	Siska Diagnostics, Inc.	Detection of 3'-azido-3'-deoxythymidine resistance
DE4129653A1 (de) *	1991-09-06	1993-03-11	Boehringer Mannheim Gmbh	Verfahren zum nachweis aehnlicher nukleinsaeuren
AU4248593A (en) *	1992-05-14	1993-12-13	Mark Holodniy	Polymerase chain reaction assays for monitoring antiviral therapy
US5827648A (en) *	1995-12-13	1998-10-27	Chiron Corporation	Differential hybridization for relative quantification of variant populations
DK0756639T3 (da) *	1994-04-19	1999-08-30	Sanquin Bloedvoorziening	Fremgangsmåder til at skelne mellem syncytium-inducerende og ikke-syncytium-inducerende varianter af den human immundefekt
US6265152B1 (en)	1995-12-22	2001-07-24	Visible Genetics Inc.	Method and kit for evaluation of HIV mutations
US6007983A (en) *	1995-12-22	1999-12-28	Visible Genetics Inc.	Method and kit for evaluation of HIV mutations
BR9704637A (pt) *	1996-01-26	1998-06-09	Innogenetics Nv	Processo para deteção de mutações induzidas por droga no gene de transcrição reversa
US6025155A (en) *	1996-04-10	2000-02-15	Chromos Molecular Systems, Inc.	Artificial chromosomes, uses thereof and methods for preparing artificial chromosomes
US20030033617A1 (en) *	1996-04-10	2003-02-13	Gyula Hadlaczky	Artificial chromosomes, uses thereof and methods for preparing artificial chromosomes
US6077697A (en) *	1996-04-10	2000-06-20	Chromos Molecular Systems, Inc.	Artificial chromosomes, uses thereof and methods for preparing artificial chromosomes
US20020160970A1 (en) *	1996-04-10	2002-10-31	Gyula Hadlaczky	Artificial chromosomes, uses thereof and methods for preparing artificial chromosomes
US6830887B2 (en)	1997-03-18	2004-12-14	Bayer Healthcare Llc	Method and kit for quantitation and nucleic acid sequencing of nucleic acid analytes in a sample
CA2335617C (en)	1998-06-24	2009-12-15	Novirio Pharmaceuticals Limited	Use of 3'-azido-2',3'-dideoxyuridine in combination with further anti-hiv drugs for the manufacture of a medicament for the treatment of hiv
US7635690B2 (en)	1999-01-22	2009-12-22	Emory University	HIV-1 mutations selected for by β-2′,3′-didehydro-2′,3′-dideoxy-5-fluorocytidine
US7115584B2 (en) *	1999-01-22	2006-10-03	Emory University	HIV-1 mutations selected for by β-2′,3′-didehydro-2′,3′-dideoxy-5-fluorocytidine
US6300075B1 (en) *	1999-02-03	2001-10-09	Ortho-Clinical Diagnostics, Inc	Enhancement of the specificity of nucleic acid amplification by carrier nucleic acid
US7074556B2 (en) *	1999-03-02	2006-07-11	Invitrogen Corporation	cDNA synthesis improvements
ES2246859T3 (es)	1999-05-28	2006-03-01	Virco Bvba	Nuevos perfiles mutacionales en la transcriptasa inversa del vih-1 correlacionadas con una resistencia fenotipica a farmacos.
CA2731495C (en) *	2000-09-01	2015-02-03	Gen-Probe Incorporated	Amplification of hiv-1 sequences for detection of sequences associated with drug-resistance mutations
CN101845446B (zh) *	2000-09-28	2016-01-20	生物源食物及科学公司	脂肪酸去饱和酶家族成员fad4、fad5、fad5-2和fad6及它们的应用
EP1356082A2 (de)	2000-10-20	2003-10-29	Virco Bvba	Mutationsprofile bei mit phänotypischer medikamentenresistenz korrelierter hiv-1-reverse-transkriptase
EP1520247B1 (de)	2002-07-01	2009-05-27	Tibotec Pharmaceuticals Ltd.	Mutationsprofile bei mit phänotypischer medikamentenresistenz korrelierter hiv-1-protease
DE60321466D1 (de)	2002-07-01	2008-07-17	Tibotec Pharm Ltd	Mit phänotypischer medikamentenresistenz korrelierte mutationsprofile in hiv-1-reverse-transkriptase
US6834479B2 (en) *	2002-10-03	2004-12-28	Src Innovations, Llc	Bagging machine having a collapsible tunnel

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU606043B2 (en) *	1985-03-28	1991-01-31	F. Hoffmann-La Roche Ag	Detection of viruses by amplification and hybridization

1989
- 1989-08-09 GB GB898918226A patent/GB8918226D0/en active Pending
1990
- 1990-08-08 CA CA002022942A patent/CA2022942C/en not_active Expired - Lifetime
- 1990-08-08 ES ES90308721T patent/ES2072983T3/es not_active Expired - Lifetime
- 1990-08-08 AU AU60828/90A patent/AU638475B2/en not_active Expired
- 1990-08-08 NZ NZ234812A patent/NZ234812A/xx unknown
- 1990-08-08 ZA ZA906263A patent/ZA906263B/xx unknown
- 1990-08-08 DK DK90308721.1T patent/DK0422762T3/da active
- 1990-08-08 DE DE69019795T patent/DE69019795T2/de not_active Expired - Lifetime
- 1990-08-08 IE IE286090A patent/IE69846B1/en not_active IP Right Cessation
- 1990-08-08 EP EP90308721A patent/EP0422762B1/de not_active Expired - Lifetime
- 1990-08-09 JP JP02211465A patent/JP3105907B2/ja not_active Expired - Lifetime
1992
- 1992-12-01 US US07/984,255 patent/US5409810A/en not_active Ceased
1997
- 1997-04-23 US US08/839,010 patent/USRE37918E1/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
US5409810A (en)	1995-04-25
IE902860A1 (en)	1991-02-27
CA2022942C (en)	1999-12-21
NZ234812A (en)	1991-09-25
GB8918226D0 (en)	1989-09-20
USRE37918E1 (en)	2002-12-03
EP0422762A2 (de)	1991-04-17
AU6082890A (en)	1991-02-14
AU638475B2 (en)	1993-07-01
EP0422762B1 (de)	1995-05-31
ZA906263B (en)	1992-04-29
ES2072983T3 (es)	1995-08-01
JPH03133400A (ja)	1991-06-06
JP3105907B2 (ja)	2000-11-06
DE69019795D1 (de)	1995-07-06
CA2022942A1 (en)	1991-02-10
IE69846B1 (en)	1996-10-02
EP0422762A3 (en)	1992-08-05
DE69019795T2 (de)	1995-11-02

Publication	Publication Date	Title
DK0422762T3 (da)	1995-07-24	Fremgangsmåde til at bedømme følsomheden af HIV-1 over for zidovudin og oligonukleotider dertil
DE69032143D1 (de)	1998-04-23	Zerstörungsfreie Prüfung von Strukturelementen
NO850909L (no)	1985-09-09	Fremgangsmaate og anordning til bruk ved detonering
BR7801477A (pt)	1979-05-22	Preparado de organossilana granulada e processo para sua obtencao
DK353378A (da)	1979-02-12	Fremgangsmaade til fr&mstilling af phosphonoacylproliner og dermed beslagtede forbindelser
NO905460L (no)	1991-06-21	Broennsonde.
DK198178A (da)	1978-11-08	Glycoprotein og fremgangsmaade til fremstilling deraf
IT1096613B (it)	1985-08-26	Composizione fluoroelastomerica e processo per la sua preparazione
DK163193C (da)	1992-06-22	Fremgangsmaade og anordning ved maaling af afstanden til et objekt
IT1084178B (it)	1985-05-25	Poli-di carbo-monofluoruro e procedimento per la sua preparazione
IT1099032B (it)	1985-09-18	Solido ceramico sagomato e procedimento per la sua fabbricazione
IT1113082B (it)	1986-01-20	Glicoproteina e processo per la sua preparazione
DK375489A (da)	1990-02-02	Fremgangsmaade til ikke-destruktiv vurdering af printkort
DK265888A (da)	1988-11-15	Fremgangsmaade til bestemmelse af fructosamin
DK268478A (da)	1978-12-16	Mercaptoacylamidobenzoylglycin og fremgangsmaade til fremstilling deraf
DE69025440D1 (de)	1996-03-28	Probensonde
NO176193C (no)	1995-02-15	Flyttbar bro
IT1099505B (it)	1985-09-18	A-aminometilen-b-formilaminopropionitrile e processo per la sua preparazione
IT1092719B (it)	1985-07-12	Pigmenti monoazoici e procedimento per la loro preparazione
IT1106131B (it)	1985-11-11	2-guanidinometil-indolina e processo per la sua preparazione
BR7802581A (pt)	1978-11-14	Instrumento de analise
FI905819A7 (fi)	1990-11-26	Maaperän koetusmenetelmä
DK113278A (da)	1978-09-16	Komposition egnet til bestemmelse af tri-iodo-thyronin og diagnosemetode der goer brug heraf
DK154229C (da)	1989-03-20	Fremgangsmaade til bloedgloedning af staal
DK112878A (da)	1978-09-16	Jordnoeddesmoerblanding og stabilisator til anvendelse deri