DK0431121T3 - Fremgangsmåde til opspaltning af threo-((2-aminophenyl)-thio)-2-hydroxy-3-(4-methoxyphenyl)- propionsyre - Google Patents
Fremgangsmåde til opspaltning af threo-((2-aminophenyl)-thio)-2-hydroxy-3-(4-methoxyphenyl)- propionsyreInfo
- Publication number
- DK0431121T3 DK0431121T3 DK90909482.3T DK90909482T DK0431121T3 DK 0431121 T3 DK0431121 T3 DK 0431121T3 DK 90909482 T DK90909482 T DK 90909482T DK 0431121 T3 DK0431121 T3 DK 0431121T3
- Authority
- DK
- Denmark
- Prior art keywords
- threo
- aminophenyl
- thio
- methoxyphenyl
- hydroxy
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- -1 (2-aminophenyl) thio Chemical group 0.000 title 1
- 238000003776 cleavage reaction Methods 0.000 title 1
- 230000007017 scission Effects 0.000 title 1
- 239000002253 acid Substances 0.000 abstract 4
- 239000000203 mixture Substances 0.000 abstract 2
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
- C07C319/26—Separation; Purification; Stabilisation; Use of additives
- C07C319/28—Separation; Purification
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU333689A HU204774B (en) | 1989-06-30 | 1989-06-30 | Process for resolving alpha-phenylglycineamide |
| HU333589A HU205896B (en) | 1989-06-30 | 1989-06-30 | Process for resolving treo-3-//2-amino-phenyl/-thio/-2-hydroxy-3-/4-methoxy-phenyl/-propionic acid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0431121T3 true DK0431121T3 (da) | 1993-10-11 |
Family
ID=26317626
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK90909482.3T DK0431121T3 (da) | 1989-06-30 | 1990-06-29 | Fremgangsmåde til opspaltning af threo-((2-aminophenyl)-thio)-2-hydroxy-3-(4-methoxyphenyl)- propionsyre |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5292933A (da) |
| EP (1) | EP0431121B1 (da) |
| JP (1) | JPH04500528A (da) |
| AT (1) | ATE93516T1 (da) |
| DE (1) | DE69002924T2 (da) |
| DK (1) | DK0431121T3 (da) |
| ES (1) | ES2060180T3 (da) |
| IE (1) | IE62410B1 (da) |
| IL (1) | IL94914A (da) |
| WO (1) | WO1991000270A1 (da) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1240651B (it) * | 1990-05-17 | 1993-12-17 | Zambon Spa | Processo per la risoluzione di derivati glicidici |
| MX2021011484A (es) * | 2019-03-22 | 2021-11-12 | Tyme Inc | Composiciones de d-metirosina y metodos para preparar las mismas. |
| WO2020232227A1 (en) | 2019-05-14 | 2020-11-19 | Tyme, Inc. | Compositions and methods for treating cancer |
| US10905698B1 (en) | 2020-05-14 | 2021-02-02 | Tyme, Inc. | Methods of treating SARS-COV-2 infections |
| US20220002227A1 (en) * | 2020-07-01 | 2022-01-06 | Tyme, Inc. | Crystalline forms of metyrosine |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL7413843A (nl) * | 1974-10-23 | 1976-04-27 | Stamicarbon | Optische scheiding van fenylglycine-amide. |
| SE449611B (sv) * | 1982-07-09 | 1987-05-11 | Tanabe Seiyaku Co | Sett att framstella 1,5-bensotiazepinderivat |
| IT1152721B (it) * | 1982-10-15 | 1987-01-07 | Luso Farmaco Inst | Risoluzione ottica dell'acido dl-alfa-2-idrossi-3-(4-metossifenil)-3-(2-amminofeniltio)propionico |
| EP0320532A1 (en) * | 1986-07-15 | 1989-06-21 | Nihon Iyakuhin Kogyo Co., Ltd. | Novel optically active carboxylic acid derivative l-lysine salt and process for production thereof |
| IT1217988B (it) * | 1988-01-28 | 1990-03-30 | Ind Chimica Profarmaco Spa | Procedimento per la risoluzione ottica di un pacemo |
| FR2630107B1 (fr) * | 1988-04-19 | 1990-06-08 | Synthelabo | Procede de preparation du (+) - (2s,3s) (amino-2 phenyl)thio)-3 hydroxy-2 (methoxy-4 phenyl)-3 propionate de methyle |
| US5008433A (en) * | 1988-05-18 | 1991-04-16 | Marion Laboratories, Inc. | 2-hydroxy-3-(4-methoxyphenyl)-3-(2-aminophenylthio)propionic acid, 8'-phenylmenthyl ester, especially for diltiazem |
| FR2637285B1 (fr) * | 1988-10-03 | 1991-04-12 | Synthelabo | Procede de preparation de derives de l'acide propionique et produits obtenus |
-
1990
- 1990-06-29 IE IE236090A patent/IE62410B1/en not_active IP Right Cessation
- 1990-06-29 DK DK90909482.3T patent/DK0431121T3/da active
- 1990-06-29 DE DE90909482T patent/DE69002924T2/de not_active Expired - Fee Related
- 1990-06-29 EP EP90909482A patent/EP0431121B1/en not_active Expired - Lifetime
- 1990-06-29 ES ES90909482T patent/ES2060180T3/es not_active Expired - Lifetime
- 1990-06-29 WO PCT/HU1990/000045 patent/WO1991000270A1/en not_active Ceased
- 1990-06-29 JP JP2508964A patent/JPH04500528A/ja active Pending
- 1990-06-29 US US07/684,892 patent/US5292933A/en not_active Expired - Fee Related
- 1990-06-29 IL IL9491490A patent/IL94914A/en not_active IP Right Cessation
- 1990-06-29 AT AT90909482T patent/ATE93516T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0431121B1 (en) | 1993-08-25 |
| JPH04500528A (ja) | 1992-01-30 |
| ATE93516T1 (de) | 1993-09-15 |
| IE62410B1 (en) | 1995-01-25 |
| IL94914A0 (en) | 1991-04-15 |
| IE902360A1 (en) | 1991-06-19 |
| US5292933A (en) | 1994-03-08 |
| DE69002924D1 (en) | 1993-09-30 |
| ES2060180T3 (es) | 1994-11-16 |
| IL94914A (en) | 1994-07-31 |
| DE69002924T2 (de) | 1993-12-23 |
| IE902360L (en) | 1990-12-30 |
| WO1991000270A1 (en) | 1991-01-10 |
| EP0431121A1 (en) | 1991-06-12 |
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