DK0444851T3 - Hexahydrobenz (cd) indoler og fremgangsmåder til fremstilling af disse - Google Patents

Hexahydrobenz (cd) indoler og fremgangsmåder til fremstilling af disse

Info

Publication number: DK0444851T3
Authority: DK; Denmark
Prior art keywords: hexahydrobenz; indoles; preparation; processes; amino
Prior art date: 1990-02-26

Application number

DK91301500.4T

Other languages

English (en)

Inventor

Thomas Joseph Kress

Marvin Robert Leanna

Barry Curtis Peterson

Michael John Martinelli

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-02-26

Filing date

1991-02-26

Publication date

1995-10-23

1991-02-26 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

1995-10-23 Application granted granted Critical

1995-10-23 Publication of DK0444851T3 publication Critical patent/DK0444851T3/da

Links

238000000034 method Methods 0.000 title abstract 3
MFVFAPQCEUCUSG-UHFFFAOYSA-N 1,2,2a,3,4,5-hexahydrobenzo[cd]indole Chemical class C1CCC2CNC3=CC=CC1=C32 MFVFAPQCEUCUSG-UHFFFAOYSA-N 0.000 title 1
WFIHFVABJQXZDE-UHFFFAOYSA-N 1,2,2a,3,4,5-hexahydrobenzo[cd]indol-4-amine Chemical class C1NC2=CC=CC3=C2C1CC(N)C3 WFIHFVABJQXZDE-UHFFFAOYSA-N 0.000 abstract 2
239000000543 intermediate Substances 0.000 abstract 2
HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
150000002576 ketones Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/90—Benzo [c, d] indoles; Hydrogenated benzo [c, d] indoles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/06—Peri-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Indole Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

DK91301500.4T 1990-02-26 1991-02-26 Hexahydrobenz (cd) indoler og fremgangsmåder til fremstilling af disse DK0444851T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US48519490A	1990-02-26	1990-02-26

Publications (1)

Publication Number	Publication Date
DK0444851T3 true DK0444851T3 (da)	1995-10-23

Family

ID=23927262

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK91301500.4T DK0444851T3 (da)	1990-02-26	1991-02-26	Hexahydrobenz (cd) indoler og fremgangsmåder til fremstilling af disse

Country Status (13)

Country	Link
EP (1)	EP0444851B1 (da)
JP (1)	JP2968070B2 (da)
KR (2)	KR0171418B1 (da)
AT (1)	ATE127454T1 (da)
CA (1)	CA2037098C (da)
DE (1)	DE69112670T2 (da)
DK (1)	DK0444851T3 (da)
ES (1)	ES2078434T3 (da)
GR (1)	GR3017777T3 (da)
HU (1)	HU215965B (da)
IE (1)	IE68887B1 (da)
IL (2)	IL97309A (da)
PH (1)	PH31173A (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL97308A (en) *	1990-02-26	1996-10-31	Lilly Co Eli	6-Substituted-hexahydrobenz (cd) indoles process for their preparation and pharmaceutical compositions containing them
US5302612A (en) *	1990-02-26	1994-04-12	Eli Lilly And Company	6-substituted-hexahydrobenz[cd]indoles

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4110339A (en) *	1977-11-25	1978-08-29	Eli Lilly And Company	4-(Di-n-propyl)amino-1,3,4,5-tetrahydrobenz[cd]indole
IL74222A (en) *	1984-02-06	1988-07-31	Lilly Co Eli	6-substituted-4-dialkylamino tetrahydrobenz(c,d)indoles,their preparation and pharmaceutical compositions comprising them
TW219933B (da) *	1990-02-26	1994-02-01	Lilly Co Eli
US5039820A (en) *	1990-02-26	1991-08-13	Eli Lilly And Company	4-amino-6-iodo-hexahydrobenz(cd)indoles
IL97308A (en) *	1990-02-26	1996-10-31	Lilly Co Eli	6-Substituted-hexahydrobenz (cd) indoles process for their preparation and pharmaceutical compositions containing them

1991
- 1991-02-20 IL IL9730991A patent/IL97309A/en not_active IP Right Cessation
- 1991-02-25 KR KR1019910003030A patent/KR0171418B1/ko not_active Expired - Fee Related
- 1991-02-25 KR KR1019910003031A patent/KR0176247B1/ko not_active Expired - Fee Related
- 1991-02-25 IE IE62491A patent/IE68887B1/en not_active IP Right Cessation
- 1991-02-25 HU HU91631A patent/HU215965B/hu unknown
- 1991-02-26 DE DE69112670T patent/DE69112670T2/de not_active Expired - Fee Related
- 1991-02-26 DK DK91301500.4T patent/DK0444851T3/da active
- 1991-02-26 EP EP91301500A patent/EP0444851B1/en not_active Expired - Lifetime
- 1991-02-26 AT AT91301500T patent/ATE127454T1/de not_active IP Right Cessation
- 1991-02-26 JP JP3055928A patent/JP2968070B2/ja not_active Expired - Fee Related
- 1991-02-26 ES ES91301500T patent/ES2078434T3/es not_active Expired - Lifetime
- 1991-02-26 CA CA002037098A patent/CA2037098C/en not_active Expired - Fee Related
- 1991-04-26 PH PH42055A patent/PH31173A/en unknown
1994
- 1994-09-22 IL IL11102794A patent/IL111027A/en not_active IP Right Cessation
1995
- 1995-10-18 GR GR950402879T patent/GR3017777T3/el unknown

Also Published As

Publication number	Publication date
EP0444851B1 (en)	1995-09-06
HU215965B (hu)	1999-03-29
IL97309A (en)	1996-11-14
IL97309A0 (en)	1992-05-25
IE68887B1 (en)	1996-07-24
JP2968070B2 (ja)	1999-10-25
ATE127454T1 (de)	1995-09-15
HU63191D0 (en)	1991-09-30
KR910021376A (ko)	1991-12-20
KR0176247B1 (ko)	1999-03-20
PH31173A (en)	1998-03-20
EP0444851A3 (en)	1992-02-19
IL111027A0 (en)	1994-11-28
GR3017777T3 (en)	1996-01-31
JPH04211653A (ja)	1992-08-03
CA2037098C (en)	2006-04-18
CA2037098A1 (en)	1991-08-27
IL111027A (en)	1996-05-14
KR0171418B1 (ko)	1999-02-01
EP0444851A2 (en)	1991-09-04
DE69112670T2 (de)	1996-03-07
ES2078434T3 (es)	1995-12-16
IE910624A1 (en)	1991-08-28
KR910021404A (ko)	1991-12-20
DE69112670D1 (de)	1995-10-12
HUT68729A (en)	1995-07-28

Publication	Publication Date	Title
DK386288D0 (da)	1988-07-11	Optiske isomere af et imidazolderivat
DK0836601T3 (da)	2009-03-16	Fremgangsmåde til optisk oprensning af enantiomert beriget benzimidasolderivater
NO992929D0 (no)	1999-06-16	Salte ut fremgangsmÕte for krystallisering av 2,4,6,8,10,12-heksanitro-2,4,6,8,10,12-heksaazatetracyklo(5.5.0.05,903,11)-dodecan
NO843053L (no)	1985-01-30	Fremgangsmaate ved fremstilling av nye hetrocykliske forbindelser
DK0786450T3 (da)	2000-07-10	Fremgangsmåde til fremstilling af enantiomerer fra O-demethyltramadol
HU9201015D0 (en)	1992-06-29	Method for producing heterocyclic 4-amino-1,3,4,5-tetrahydro-benz(cd)indoles
ATE138911T1 (de)	1996-06-15	Hexahydro(cd>indole
DK0424350T3 (da)	1995-04-10	Derivater af 1,4-dideoxy-1,4-imino-D-mannitol
HU9201014D0 (en)	1992-06-29	Method for producing heterocyclic 4-amino-1,2,2a,3,4,5-hexahydro(cd)indole derivatives
DK2143715T3 (da)	2011-12-05	Fremgangsmåde til at tilvejebringe rene enantiomerer af et pyridazinonderivat
ES2078434T3 (es)	1995-12-16	Hexahidrobenz(cd)indoles y procedimiento para su preparacion.
DE69614936D1 (de)	2001-10-11	d4T polymorphe Form I Verfahren
MA24206A1 (fr)	1997-12-31	Procede de fabrication de derives 1-(amino-alkyl) indole
EP0474250A3 (en)	1993-04-07	Enzymatic process for separating the optical isomers of racemic 1,2-diols
ATE143362T1 (de)	1996-10-15	6-substituierte hexahydrobenz(cd>indole