DK0456183T3 - Spiro-dibenzosuberan-derivater - Google Patents

Spiro-dibenzosuberan-derivater

Info

Publication number: DK0456183T3
Authority: DK; Denmark
Prior art keywords: alkyl; hydrogen; derivatives; dibenzosuberane; spiro
Prior art date: 1990-05-07

Application number

DK91107396.3T

Other languages

English (en)

Inventor

Hiromu Matsumura

Hiroshi Hashizume

Masami Eigyo

Makoto Adachi

Toshisada Yano

Akira Matsushita

Original Assignee

Shionogi & Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-05-07

Filing date

1991-05-07

Publication date

1995-11-20

1991-05-07 Application filed by Shionogi & Co filed Critical Shionogi & Co

1995-11-20 Application granted granted Critical

1995-11-20 Publication of DK0456183T3 publication Critical patent/DK0456183T3/da

Links

-1 Spiro dibenzosuberane derivatives Chemical class 0.000 title abstract 2
125000000217 alkyl group Chemical group 0.000 abstract 3
229910052739 hydrogen Inorganic materials 0.000 abstract 3
239000001257 hydrogen Substances 0.000 abstract 3
150000002431 hydrogen Chemical class 0.000 abstract 2
208000024827 Alzheimer disease Diseases 0.000 abstract 1
201000006474 Brain Ischemia Diseases 0.000 abstract 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
206010070511 Hypoxic-ischaemic encephalopathy Diseases 0.000 abstract 1
102000004868 N-Methyl-D-Aspartate Receptors Human genes 0.000 abstract 1
108090001041 N-Methyl-D-Aspartate Receptors Proteins 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
125000003342 alkenyl group Chemical group 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
239000005557 antagonist Substances 0.000 abstract 1
230000002555 anti-neurodegenerative effect Effects 0.000 abstract 1
125000003710 aryl alkyl group Chemical group 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
230000002265 prevention Effects 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/20—Spiro-condensed ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/12—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/96—Spiro-condensed ring systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Neurosurgery (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Neurology (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Biomedical Technology (AREA)
Public Health (AREA)
Vascular Medicine (AREA)
Hospice & Palliative Care (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Psychiatry (AREA)
Urology & Nephrology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heat Sensitive Colour Forming Recording (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Other In-Based Heterocyclic Compounds (AREA)
Indole Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Plural Heterocyclic Compounds (AREA)

DK91107396.3T 1990-05-07 1991-05-07 Spiro-dibenzosuberan-derivater DK0456183T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP11812690		1990-05-07

Publications (1)

Publication Number	Publication Date
DK0456183T3 true DK0456183T3 (da)	1995-11-20

Family

ID=14728685

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK91107396.3T DK0456183T3 (da)	1990-05-07	1991-05-07	Spiro-dibenzosuberan-derivater

Country Status (10)

Country	Link
EP (1)	EP0456183B1 (da)
JP (1)	JPH04225953A (da)
KR (1)	KR910019978A (da)
AT (1)	ATE128705T1 (da)
CA (1)	CA2040750A1 (da)
DE (1)	DE69113505T2 (da)
DK (1)	DK0456183T3 (da)
ES (1)	ES2080182T3 (da)
GR (1)	GR3017868T3 (da)
HU (1)	HUT58057A (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5538986A (en) *	1993-12-06	1996-07-23	Schering Corporation	Tricyclic derivatives, compositions and methods of use
US5760246A (en)	1996-12-17	1998-06-02	Biller; Scott A.	Conformationally restricted aromatic inhibitors of microsomal triglyceride transfer protein and method
UA73749C2 (en) *	1999-11-01	2005-09-15		Diarylenines
ES2315494T3 (es)	2002-04-26	2009-04-01	Schering Corporation	Antagonistas muscarinicos.
US7101917B2 (en)	2003-04-14	2006-09-05	Hoffmann-La Roche Inc.	Mitochrondrial permeability transition pore affinity labels and modulators
AU2004233863B2 (en)	2003-04-24	2010-06-17	Incyte Holdings Corporation	Aza spiro alkane derivatives as inhibitors of metalloproteases
AU2006229672B8 (en)	2005-02-25	2009-01-08	Irm Llc	Spiro-containing compounds and compositions as modulators of steroid hormone nuclear receptors
JP5712289B2 (ja)	2011-06-07	2015-05-07	パイオニア株式会社	インピーダンス整合装置、制御方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8719199D0 (en) *	1987-08-13	1987-09-23	Merck Sharp & Dohme	Chemical compounds

1991
- 1991-04-09 JP JP3104807A patent/JPH04225953A/ja active Pending
- 1991-04-18 CA CA002040750A patent/CA2040750A1/en not_active Abandoned
- 1991-05-04 KR KR1019910007257A patent/KR910019978A/ko not_active Ceased
- 1991-05-06 HU HU911520A patent/HUT58057A/hu unknown
- 1991-05-07 DE DE69113505T patent/DE69113505T2/de not_active Expired - Fee Related
- 1991-05-07 EP EP91107396A patent/EP0456183B1/en not_active Expired - Lifetime
- 1991-05-07 DK DK91107396.3T patent/DK0456183T3/da active
- 1991-05-07 ES ES91107396T patent/ES2080182T3/es not_active Expired - Lifetime
- 1991-05-07 AT AT91107396T patent/ATE128705T1/de not_active IP Right Cessation
1995
- 1995-10-25 GR GR950402972T patent/GR3017868T3/el unknown

Also Published As

Publication number	Publication date
HUT58057A (en)	1992-01-28
EP0456183A3 (en)	1992-04-22
CA2040750A1 (en)	1991-11-08
DE69113505D1 (de)	1995-11-09
GR3017868T3 (en)	1996-01-31
EP0456183B1 (en)	1995-10-04
HU911520D0 (en)	1991-11-28
JPH04225953A (ja)	1992-08-14
ES2080182T3 (es)	1996-02-01
ATE128705T1 (de)	1995-10-15
DE69113505T2 (de)	1996-04-04
EP0456183A2 (en)	1991-11-13
KR910019978A (ko)	1991-12-19

Publication	Publication Date	Title
BR9004698A (pt)	1991-09-10	Derivados de 4-benzoil-isoxazol
ATE243209T1 (de)	2003-07-15	Tetrahydro gamma-carboline
ES2080182T3 (es)	1996-02-01	Derivados espiro dibenzosuberano.
DK0902018T3 (da)	2008-10-20	2-(arylpheny)amino-imidazolinderivater
DE69623497D1 (de)	2002-10-10	1-methylcarbapenem-derivate
EP0299493A3 (en)	1990-05-23	N-û(2-oxopyrrolidin-1-yl)-acetyl¨piperazine derivatives and drug for senile dementia
SE9001269D0 (sv)	1990-04-06	2-substituted n,n-ditrimethoxybenzoyl piperazines,a preparation process of the same and therapeutic compositions containing them
NO910904D0 (no)	1991-03-07	Fremgangsmaate for fremstilling av en substituert aminforbindelse.
FI956151A0 (fi)	1995-12-20	Iskeemisissä taudeissa käyttökelpoisia bentseenijohdannaisia
DK0420224T3 (da)	1993-04-05	Anthihepatopatisk middel
EP1112998A4 (en)	2002-09-11	Amine derivatives
ES2141134T3 (es)	2000-03-16	Derivados de carbamoil pirrolidona para el tratamiento de la depresion y de los trastornos cerebrovasculares.
ATE103490T1 (de)	1994-04-15	Derivate der p-guanidinobenzoesaeure zur behandlung der zerebrovaskulaeren kontraktion.
ATE100449T1 (de)	1994-02-15	1,3-dioxolan-benzoesaeure und derivate davon.