DK0460065T3 - Fremgangsmåde til at fremkalde formering af CD4-lymfocytter - Google Patents

Fremgangsmåde til at fremkalde formering af CD4-lymfocytter

Info

Publication number: DK0460065T3
Authority: DK; Denmark
Prior art keywords: lymphocytes; inducing; methyl ester; leucine methyl; alkyl ester
Prior art date: 1989-02-21

Application number

DK90904107.1T

Other languages

English (en)

Inventor

Kam Hung Leung

Robert Martin Townsend

Original Assignee

Terumo Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-02-21

Filing date

1990-02-08

Publication date

1994-09-26

1990-02-08 Application filed by Terumo Corp filed Critical Terumo Corp

1994-09-26 Application granted granted Critical

1994-09-26 Publication of DK0460065T3 publication Critical patent/DK0460065T3/da

Links

210000004698 lymphocyte Anatomy 0.000 title abstract 4
230000001939 inductive effect Effects 0.000 title 1
230000035755 proliferation Effects 0.000 title 1
AJMOLNFDYWTVQW-QWRGUYRKSA-N L-leucyl-l-leucine methyl ester Chemical compound COC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CC(C)C AJMOLNFDYWTVQW-QWRGUYRKSA-N 0.000 abstract 2
108010062054 leucyl-leucine-methyl ester Proteins 0.000 abstract 2
QVDXUKJJGUSGLS-LURJTMIESA-N methyl L-leucinate Chemical compound COC(=O)[C@@H](N)CC(C)C QVDXUKJJGUSGLS-LURJTMIESA-N 0.000 abstract 2
210000003819 peripheral blood mononuclear cell Anatomy 0.000 abstract 2
210000003171 tumor-infiltrating lymphocyte Anatomy 0.000 abstract 2
108010016626 Dipeptides Proteins 0.000 abstract 1
102000000588 Interleukin-2 Human genes 0.000 abstract 1
108010002350 Interleukin-2 Proteins 0.000 abstract 1
229940122760 T cell stimulant Drugs 0.000 abstract 1
125000005907 alkyl ester group Chemical group 0.000 abstract 1
210000001616 monocyte Anatomy 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/10—Cellular immunotherapy characterised by the cell type used
- A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/41—Vertebrate antigens
- A61K40/42—Cancer antigens
- A61K40/428—Undefined tumor antigens, e.g. tumor lysate or antigens targeted by cells isolated from tumor
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16051—Methods of production or purification of viral material

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Biomedical Technology (AREA)
Organic Chemistry (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Genetics & Genomics (AREA)
Bioinformatics & Cheminformatics (AREA)
Biotechnology (AREA)
Immunology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Animal Behavior & Ethology (AREA)
Microbiology (AREA)
General Engineering & Computer Science (AREA)
Biochemistry (AREA)
Cell Biology (AREA)
Hematology (AREA)
Medicinal Chemistry (AREA)
Virology (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DK90904107.1T 1989-02-21 1990-02-08 Fremgangsmåde til at fremkalde formering af CD4-lymfocytter DK0460065T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US31342189A	1989-02-21	1989-02-21

Publications (1)

Publication Number	Publication Date
DK0460065T3 true DK0460065T3 (da)	1994-09-26

Family

ID=23215624

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK90904107.1T DK0460065T3 (da)	1989-02-21	1990-02-08	Fremgangsmåde til at fremkalde formering af CD4-lymfocytter

Country Status (7)

Country	Link
EP (1)	EP0460065B1 (da)
AT (1)	ATE110770T1 (da)
AU (1)	AU645488B2 (da)
DE (1)	DE69012105T2 (da)
DK (1)	DK0460065T3 (da)
HU (1)	HU902289D0 (da)
WO (1)	WO1990010059A1 (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2074879T3 (es) *	1991-01-16	1995-09-16	Schering Corp	Uso de interleuquina-10 en inmunoterapia adoptiva de cancer.
US5374549A (en) *	1991-01-31	1994-12-20	Terumo Corporation	Process of enriching adherent CD4+ T cells from monocyte depleted peripheral blood mononuclear cells with interleukin 2 and interleukin 4
DE4410136A1 (de) *	1993-03-31	1994-10-06	Boehringer Mannheim Gmbh	Tumorizide T-Lymphozyten
US6652850B1 (en)	1993-09-13	2003-11-25	Aventis Pharmaceuticals Inc.	Adeno-associated viral liposomes and their use in transfecting dendritic cells to stimulate specific immunity
US5834441A (en) *	1993-09-13	1998-11-10	Rhone-Poulenc Rorer Pharmaceuticals Inc.	Adeno-associated viral (AAV) liposomes and methods related thereto
WO1996016674A1 (en) *	1994-12-01	1996-06-06	New England Deaconess Hospital Corporation	In vitro t-lymphopoiesis system
CN107502589A (zh) *	2017-08-04	2017-12-22	北京世纪劲得生物技术有限公司	一种肿瘤浸润淋巴细胞与单个核细胞共培养方法
CA3158133A1 (en)	2020-04-28	2021-11-04	Lyell Immunopharma, Inc.	Methods for culturing cells

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4849329A (en) *	1986-05-30	1989-07-18	E. I. Du Pont De Nemours And Company	Process for preparing lymphokine activated killer cells
SE459008B (sv) *	1986-09-04	1989-05-29	Bioinvent Int Ab	Saett att framsstaella humana monoklonala antikroppar
CA1300058C (en) *	1987-01-29	1992-05-05	Joseph D. Irr	Process for preparing activated killer cells
US4808151A (en) *	1987-04-27	1989-02-28	E. I. Du Pont De Nemours And Company	Simplified method for the preparation of human lymphokine activated killer cells
SE461985B (sv) *	1988-09-13	1990-04-23	Bioinvent Int Ab	In vitro immunisering av lymfocytinnehaallande cellpopulationer och materialsats daerfoer

1990
- 1990-02-08 WO PCT/US1990/000611 patent/WO1990010059A1/en not_active Ceased
- 1990-02-08 DE DE69012105T patent/DE69012105T2/de not_active Expired - Fee Related
- 1990-02-08 HU HU902289A patent/HU902289D0/hu unknown
- 1990-02-08 AT AT90904107T patent/ATE110770T1/de not_active IP Right Cessation
- 1990-02-08 DK DK90904107.1T patent/DK0460065T3/da active
- 1990-02-08 EP EP90904107A patent/EP0460065B1/en not_active Expired - Lifetime
- 1990-02-08 AU AU51965/90A patent/AU645488B2/en not_active Ceased

Also Published As

Publication number	Publication date
AU645488B2 (en)	1994-01-20
WO1990010059A1 (en)	1990-09-07
AU5196590A (en)	1990-09-26
DE69012105D1 (en)	1994-10-06
DE69012105T2 (de)	1994-12-22
ATE110770T1 (de)	1994-09-15
EP0460065A1 (en)	1991-12-11
HU902289D0 (en)	1991-11-28
EP0460065B1 (en)	1994-08-31

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