DK0465121T3 - Stabile salte af 4"-deoxy-4"-epi-methylaminoavermectin Bla/Blb - Google Patents

Stabile salte af 4"-deoxy-4"-epi-methylaminoavermectin Bla/Blb

Info

Publication number
DK0465121T3
DK0465121T3 DK91305815.2T DK91305815T DK0465121T3 DK 0465121 T3 DK0465121 T3 DK 0465121T3 DK 91305815 T DK91305815 T DK 91305815T DK 0465121 T3 DK0465121 T3 DK 0465121T3
Authority
DK
Denmark
Prior art keywords
acid salt
blb
epi
deoxy
stable salts
Prior art date
Application number
DK91305815.2T
Other languages
English (en)
Inventor
Raymond Cvetovich
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Application granted granted Critical
Publication of DK0465121T3 publication Critical patent/DK0465121T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Environmental Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Dentistry (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Steroid Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Silicon Polymers (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Fodder In General (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
DK91305815.2T 1990-06-28 1991-06-27 Stabile salte af 4"-deoxy-4"-epi-methylaminoavermectin Bla/Blb DK0465121T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US54522990A 1990-06-28 1990-06-28

Publications (1)

Publication Number Publication Date
DK0465121T3 true DK0465121T3 (da) 1996-03-18

Family

ID=24175383

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91305815.2T DK0465121T3 (da) 1990-06-28 1991-06-27 Stabile salte af 4"-deoxy-4"-epi-methylaminoavermectin Bla/Blb

Country Status (21)

Country Link
US (1) US5288710A (da)
EP (1) EP0465121B1 (da)
JP (1) JPH0822870B2 (da)
KR (1) KR100224292B1 (da)
AT (1) ATE134377T1 (da)
AU (1) AU641777B2 (da)
CA (1) CA2045864C (da)
CY (1) CY1949A (da)
DE (1) DE69117223T2 (da)
DK (1) DK0465121T3 (da)
ES (1) ES2084110T3 (da)
FI (1) FI97890C (da)
GR (1) GR3019067T3 (da)
HK (1) HK157096A (da)
IE (1) IE71175B1 (da)
IL (1) IL98599A (da)
LV (1) LV5740B4 (da)
NO (2) NO2001007I2 (da)
NZ (1) NZ238705A (da)
PT (1) PT98117B (da)
ZA (1) ZA914961B (da)

Families Citing this family (62)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994027598A1 (en) * 1993-05-26 1994-12-08 Commonwealth Scientific And Industrial Research Organisation Antiparasitic compositions
AU687062B2 (en) * 1993-05-26 1998-02-19 Commonwealth Scientific And Industrial Research Organisation Controlled release antiparasitic compositions
NZ273129A (en) * 1993-08-19 1996-08-27 Merck & Co Inc 4"-deoxy-4"-epi-methylamino avermectin b1a/b1b benzoic acid salt hemihydrate; pesticidal compositions
US6486195B1 (en) * 1993-08-19 2002-11-26 Merck & Co., Inc. Thermodynamically stable crystal form of 4″-deoxy-4″-epi-methylamino avermectin B1a/B1b benzoic acid salt and processes for its preparation
US5362863A (en) * 1993-09-29 1994-11-08 Merck & Co., Inc. Process for the preparation of 4"-amino avermectin compounds
CN1281127C (zh) 1995-11-08 2006-10-25 麦克公司 农药制剂
AU768262B2 (en) * 1995-11-08 2003-12-04 Merck Sharp & Dohme Corp. Pesticidal formulation
BR9611354C1 (pt) * 1995-11-08 2007-06-12 Merck & Co Inc composição pesticida de gránulo solúvel, método para o controle de insetos agrìcolas, para a prevenção ou tratamento de infestações de insetos de plantas ou de produtos de plantas, e processo para a preparação de uma formulação pesticida de gránulo solúvel
US20050192319A1 (en) * 1996-09-19 2005-09-01 Albert Boeckh Spot-on formulations for combating parasites
US6054140A (en) * 1997-03-21 2000-04-25 Biogenesis S.A. Long acting injectable parasiticidal composition and the process for its preparation
WO1999025187A2 (en) * 1997-11-14 1999-05-27 Novartis Ag Pesticidal compositions of emamectin
GB2346807B (en) * 1997-12-23 2003-05-07 Novartis Ag Use of macrolides in pest control
US6486128B1 (en) 1999-04-08 2002-11-26 Schering-Plough Veterinary Corporation Method of using emamectin to treat fish parasites
AR006063A4 (es) * 1999-04-17 1999-08-11 Romario S R L Bandeja termica para pizzas
GB9926887D0 (en) 1999-11-12 2000-01-12 Novartis Ag Organic compounds
EG23124A (en) 2001-02-27 2004-04-28 Syngenta Participations Ag Avermectins substituted in the 4-position having pesticidal properties
CR6574A (es) * 2001-02-27 2004-10-28 Syngenta Participations Ag Sales de avermectinas substituidas en la posicion 4 con propiedades plaguicidas
JP4701538B2 (ja) 2001-05-21 2011-06-15 住友化学株式会社 農業害虫防除剤組成物
AR036486A1 (es) 2001-08-28 2004-09-15 Syngenta Participations Ag Derivados 4"-desoxi-4"-(s)-amino avermectina, composicion plaguicida, procedimiento para la preparacion de esa composicion, metodo para controlar plagas, y uso de estos derivados para preparar una composicion
DE10203688A1 (de) 2002-01-31 2003-08-07 Bayer Cropscience Ag Synergistische insektizide Mischungen
DE10207242A1 (de) * 2002-02-21 2003-09-04 Bayer Cropscience Ag Synergistische insektizide Mischungen
DE10207241A1 (de) * 2002-02-21 2003-09-04 Bayer Cropscience Ag Synergistische insektizide Mischungen
EP1497283A4 (en) * 2002-03-22 2006-01-11 Lg Life Sciences Ltd (2S) -N-5-AMINO (IMINO) METHYL-2-THIENYL METHYL-1- (2R) -2- (CARBOXYMETHYL) AMINO) 3,3-DIPHENYLPROPANOYL -2-PYRROLIDINE CARBOXAMIDE MALEIC ACID SALT AND PROCESS OF PREPARATION CORRESPONDING
TW200407330A (en) 2002-05-07 2004-05-16 Syngenta Participations Ag 4"-Deoxy-4"-(S)-amido avermectin derivatives
GB0302308D0 (en) 2003-01-31 2003-03-05 Syngenta Participations Ag Avermectin and avermectin monosaccharide derivatives substituted in the 4"- or 4'-position having pesticidal properties
GB0302310D0 (en) 2003-01-31 2003-03-05 Syngenta Participations Ag Avermectin- and avermectin monosaccharide derivatives substituted in the 4"- or 4' - positionhaving pesticidal properties
GB0320176D0 (en) 2003-08-28 2003-10-01 Syngenta Participations Ag Avermectins and avermectin monosaccharides substitued in the 4'-and 4"-positionhaving pesticidal properties
DE602005009381D1 (de) 2004-09-23 2008-10-09 Schering Plough Ltd Bekämpfung von parasiten in tieren durch verwendung neuer trifluormethansulfonanilidoximetherderivate
JP4750126B2 (ja) * 2004-11-19 2011-08-17 シェーリング−プラウ・リミテッド 殺寄生虫薬２−フェニル−３−（１ｈ−ピロール−２−イル）アクリロニトリル誘導体の使用による動物における寄生虫の制御
EP1890547A2 (en) * 2005-06-09 2008-02-27 Schering-Plough Ltd. Control of parasites in animals by n-[(phenyloxy)phenyl]-1,1,1-trifluoromethanesulfonamide and n-[(phenylsulfanyl)phenyl]-1,1,1-trifluoromethanesulfonamide derivatives
US8119667B2 (en) * 2005-12-29 2012-02-21 Schering-Plough Animal Health Corporation Carbonates of fenicol antibiotics
EP1849363A1 (en) * 2006-03-09 2007-10-31 Cheminova A/S Synergistic combination of glutamate- and GABA-gated chloride agonist pesticide and at least one of Vitamin E or Niacin
US20070238700A1 (en) * 2006-04-10 2007-10-11 Winzenberg Kevin N N-phenyl-1,1,1-trifluoromethanesulfonamide hydrazone derivative compounds and their usage in controlling parasites
TWI422328B (zh) 2006-06-19 2014-01-11 Univ California 結合有殺線蟲之種子塗覆物的生物控制劑
FR2906469B1 (fr) * 2006-09-28 2008-11-28 Galderma Sa Utilisation de composes de la famille des avermectines pour le traitement de desordres dermatologiques chez l'homme
CN101605756A (zh) * 2006-12-13 2009-12-16 先灵-普劳有限公司 氟苯尼考及其类似物的水溶性前药
WO2008076256A1 (en) * 2006-12-13 2008-06-26 Schering-Plough Ltd. Water-soluble prodrugs of chloramphenicol, thiamphenicol, and analogs thereof
DE102007002872A1 (de) 2007-01-15 2008-07-17 Alpha-Biocare Gmbh Verwendung von Avermectin-Derivaten zur Behandlung gegen Parasiten von Fischen
TWI430995B (zh) 2007-06-26 2014-03-21 Du Pont 萘異唑啉無脊椎有害動物控制劑
DK2182945T3 (da) 2007-06-27 2015-11-16 Du Pont Fremgangsmåde til bekæmpelse af skadedyr hos dyr
TWI556741B (zh) 2007-08-17 2016-11-11 英特威特國際股份有限公司 異唑啉組成物及其作為抗寄生蟲藥上的應用
TWI401023B (zh) 2008-02-06 2013-07-11 Du Pont 中離子農藥
WO2010014566A2 (en) * 2008-07-30 2010-02-04 Intervet International B.V. Process for preparing oxazoline-protected aminodiol compounds useful as intermediates to florfenicol
CN102355891A (zh) 2009-03-17 2012-02-15 英特威国际有限公司 大环内酯药物递送系统
UA107804C2 (xx) 2009-08-05 2015-02-25 Du Pont Суміші мезоіонних пестицидів
EP2461684A2 (en) 2009-08-05 2012-06-13 E. I. du Pont de Nemours and Company Mesoionic pesticides
UA110924C2 (uk) 2009-08-05 2016-03-10 Е. І. Дю Пон Де Немур Енд Компані Мезоіонні пестициди
AU2010279587A1 (en) 2009-08-05 2012-02-09 E. I. Du Pont De Nemours And Company Mesoionic pesticides
EP2576523B1 (en) 2010-05-27 2016-01-13 E. I. du Pont de Nemours and Company Crystalline form of 4-[5 - [3 -chloro-5 -(trifluoromethyl)phenyl] -4,5 -dihydro-5 -(trifluoromethyl)-3 - isoxazolyl]-n-[2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl]-1- naphthalenecarboxamide
AR081970A1 (es) 2010-06-24 2012-10-31 Intervet Int Bv Formulacion inyectable de una lactona macrociclica y levamisol, formulacion y uso veterinario
WO2012054328A1 (en) 2010-10-20 2012-04-26 Galderma S.A. Method of treating hemorrhoids using macrocyclic lactone compound
WO2012087630A1 (en) 2010-12-20 2012-06-28 E.I. Du Pont De Nemours And Company Pyridine and pyrimidine compounds for controlling invertebrate
JP6002148B2 (ja) 2010-12-27 2016-10-05 インターベット インターナショナル ベー． フェー． 経表面局所イソオキサゾリン製剤
CN103260620A (zh) 2010-12-27 2013-08-21 英特维特国际股份有限公司 包含三缩四乙二醇的外用局部异噁唑啉制剂
BR122020017359B1 (pt) 2011-07-28 2021-10-13 Syngenta Participations Ag Método para controle de uma praga de nemátodos
WO2013158422A1 (en) 2012-04-17 2013-10-24 E. I. Du Pont De Nemours And Company Heterocyclic compounds for controlling invertebrate pests
US9643991B2 (en) 2015-06-08 2017-05-09 Rotam Agrochem International Company Limited Process for preparing a novel crystalline form of emamectin benzoate and use the same
US9409920B1 (en) * 2015-06-08 2016-08-09 Rotam Agrochem International Company Limited Method for purifying emamectin benzoate and compositions comprising the same
CN107344954B (zh) * 2017-08-07 2020-08-11 河北蓝泰化工科技有限公司 增效型甲氨基阿维菌素b1或b2的盐及制备方法和应用
CN108840893A (zh) * 2018-07-01 2018-11-20 李万强 一种甲氨基阿维菌素苯甲酸盐的新晶型及其制备方法
CN108864230B (zh) * 2018-07-26 2021-05-14 河北威远生物化工有限公司 一种有机磷基团取代的阿维菌素衍生物及其制备方法和应用
WO2026150121A1 (en) 2025-01-13 2026-07-16 Syngenta Crop Protection Ag Mixtures for controlling infestation of plants

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4366309A (en) * 1980-03-14 1982-12-28 Schering Corporation Derivatives of antibiotic AR-5 components
US4321361A (en) * 1980-06-12 1982-03-23 Eli Lilly And Company Demycinosyltylosin and process for its production
US4427663A (en) * 1982-03-16 1984-01-24 Merck & Co., Inc. 4"-Keto-and 4"-amino-4"-deoxy avermectin compounds and substituted amino derivatives thereof
US4831016A (en) * 1986-10-31 1989-05-16 Merck & Co., Inc. Reduced avermectin derivatives
US4874749A (en) * 1987-07-31 1989-10-17 Merck & Co., Inc. 4"-Deoxy-4-N-methylamino avermectin Bla/Blb

Also Published As

Publication number Publication date
FI97890B (fi) 1996-11-29
AU641777B2 (en) 1993-09-30
JPH05306294A (ja) 1993-11-19
NO178339B (no) 1995-11-27
EP0465121B1 (en) 1996-02-21
ZA914961B (en) 1992-07-29
FI913137A0 (fi) 1991-06-27
NO912535D0 (no) 1991-06-27
NO178339C (no) 1996-03-06
KR920000781A (ko) 1992-01-29
FI913137L (fi) 1991-12-29
DE69117223T2 (de) 1996-09-12
IL98599A (en) 1995-06-29
ES2084110T3 (es) 1996-05-01
PT98117B (pt) 1998-12-31
CA2045864A1 (en) 1991-12-29
LV5740B4 (lv) 1997-12-20
NZ238705A (en) 1993-07-27
JPH0822870B2 (ja) 1996-03-06
HK157096A (en) 1996-08-23
US5288710A (en) 1994-02-22
AU7939291A (en) 1992-01-02
DE69117223D1 (de) 1996-03-28
LV5740A4 (lv) 1996-08-20
EP0465121A1 (en) 1992-01-08
GR3019067T3 (en) 1996-05-31
PT98117A (pt) 1993-10-29
CY1949A (en) 1991-06-27
CA2045864C (en) 2001-11-27
IE71175B1 (en) 1997-01-29
NO2001007I2 (no) 2007-02-26
KR100224292B1 (ko) 1999-10-15
IE912251A1 (en) 1992-01-01
NO912535L (no) 1991-12-30
ATE134377T1 (de) 1996-03-15
IL98599A0 (en) 1992-07-15
FI97890C (fi) 1997-03-10

Similar Documents

Publication Publication Date Title
DE69117223D1 (de) Stabile Salze von 4"-Desoxy-4"-epimethylamino-Avermectin-Bla/Blb
ES2126068T3 (es) Derivados de estilbeno citotoxicos y composicion farmaceutica que los contiene.
EP0990648A4 (en) DERIVATIVES OF 4-CHINOLOL AND AGRICULTURAL AND GARDENING BACTERICIDES THAT CONTAIN THEM AS AN ACTIVE COMPONENT
AU2724292A (en) Antiviral 4-substituted-2-deoxy-2,3-didehydro-derivatives of alpha-d-neuraminic acid
BR9407169A (pt) Derivados de pirazol
AR241082A1 (es) Nuevos derivados de pirazol utiles como agentes herbicidas, las composiciones herbicidas que los contienen y los procedimientos para producir estos derivados de pirazol".
DE69023321D1 (de) Antipicornaviral-Pyridazinamine.
ATE90685T1 (de) Disaccharidderivate.
TR27538A (tr) Bir alkali bilesen varliginda bir alkil kuaterner azot tuzu iceren sulu dezenfektan terkipleri.
DK390384A (da) Midler med antimikrobiel virkning indeholdende derivater af benzoesyre og deres anvendelse som desinficerende laegemidler eller konserveringsmidler
ES2079542T3 (es) Agente herbicida sinergico.
IL103417A (en) Alkyl 5- 2-(2, 5-dialkoxyphenyl) ethyl9-2-hydroxybenzoates their preparation and pharmaceutical compositions containing them
ES2058097T3 (es) Agente antibacterial para su uso en mamiferos y que comprende derivados de cefalosporina como ingrediente activo.
GB8526612D0 (en) Diphenyl ether derivatives
MA21087A1 (fr) Herbicides de type ether de diphenyle .
DE3577970D1 (de) Desinfektionszusammensetzungen.
ES2063046T3 (es) Procedimiento para la preparacion y utilizacion de 4-oxo-4-((r)-fenil)-butenoil-salicilatos y composiciones farmaceuticas que los contienen.
ES246561Y (es) Mueble infantil de usos multiples