DK0466933T3 - Bicyclolactamderivat - Google Patents

Bicyclolactamderivat

Info

Publication number: DK0466933T3
Authority: DK; Denmark
Prior art keywords: effect; bicyclolactam; cerebral; cyano; nitro
Prior art date: 1990-02-02

Application number

DK91903619.4T

Other languages

English (en)

Inventor

Akihiro Kawaguchi

Atsushi Satoh

Makoto Kajitani

Mitsugi Yasumoto

Junji Yamamoto

Original Assignee

Taiho Pharmaceutical Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-02-02

Filing date

1991-01-30

Publication date

1996-01-02

1991-01-30 Application filed by Taiho Pharmaceutical Co Ltd filed Critical Taiho Pharmaceutical Co Ltd

1996-01-02 Application granted granted Critical

1996-01-02 Publication of DK0466933T3 publication Critical patent/DK0466933T3/da

Links

230000002490 cerebral effect Effects 0.000 abstract 2
230000000694 effects Effects 0.000 abstract 2
208000024827 Alzheimer disease Diseases 0.000 abstract 1
208000002381 Brain Hypoxia Diseases 0.000 abstract 1
206010039966 Senile dementia Diseases 0.000 abstract 1
230000003213 activating effect Effects 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
230000009517 anoxic brain damage Effects 0.000 abstract 1
125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 abstract 1
208000029028 brain injury Diseases 0.000 abstract 1
125000004093 cyano group Chemical group *C#N 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
125000005843 halogen group Chemical group 0.000 abstract 1
230000004060 metabolic process Effects 0.000 abstract 1
125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
230000002633 protecting effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/34—Oxygen atoms in position 2
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/46—Iso-indoles; Hydrogenated iso-indoles with an oxygen atom in position 1
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pyrane Compounds (AREA)
Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
Quinoline Compounds (AREA)
Other In-Based Heterocyclic Compounds (AREA)
Indole Compounds (AREA)

DK91903619.4T 1990-02-02 1991-01-30 Bicyclolactamderivat DK0466933T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP2475490		1990-02-02

Publications (1)

Publication Number	Publication Date
DK0466933T3 true DK0466933T3 (da)	1996-01-02

Family

ID=12146933

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK91903619.4T DK0466933T3 (da)	1990-02-02	1991-01-30	Bicyclolactamderivat

Country Status (13)

Country	Link
US (1)	US5185344A (da)
EP (2)	EP0668268A3 (da)
JP (1)	JP2676170B2 (da)
KR (1)	KR940004059B1 (da)
AT (1)	ATE130605T1 (da)
AU (1)	AU627399B2 (da)
CA (1)	CA2050587C (da)
DE (1)	DE69114778T2 (da)
DK (1)	DK0466933T3 (da)
ES (1)	ES2083568T3 (da)
GR (1)	GR3018235T3 (da)
HU (1)	HU211635A9 (da)
WO (1)	WO1991011434A1 (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP3161948B2 (ja) *	1995-06-12	2001-04-25	大鵬薬品工業株式会社	ビシクロラクタム化合物
US6159987A (en) *	1994-03-28	2000-12-12	Taiho Pharmaceuticals, Co.	Bicyclolactam compounds, use thereof and intermediates for preparing thereof
WO1995026187A1 (fr) *	1994-03-28	1995-10-05	Taiho Pharmaceutical Company, Ltd.	Agent anxiolytique

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4619937A (en) *	1984-02-02	1986-10-28	Warner-Lambert Company	Saturated bicyclic lactam acids and derivatives as cognition activators
US4758585A (en) *	1985-08-16	1988-07-19	Warner-Lambert Company	Saturated cycloalkyl (B) pyrrol-1 (2H)- acetic acid amides and derivatives thereof
US4621097A (en) *	1985-08-16	1986-11-04	Warner-Lambert Company	Saturated cycloalkyl[c] pyrrole-2(1H)-acetic acid amides and derivatives thereof

1991
- 1991-01-30 WO PCT/JP1991/000116 patent/WO1991011434A1/ja not_active Ceased
- 1991-01-30 AT AT91903619T patent/ATE130605T1/de not_active IP Right Cessation
- 1991-01-30 JP JP3503458A patent/JP2676170B2/ja not_active Expired - Fee Related
- 1991-01-30 KR KR1019910701243A patent/KR940004059B1/ko not_active Expired - Fee Related
- 1991-01-30 CA CA002050587A patent/CA2050587C/en not_active Expired - Fee Related
- 1991-01-30 EP EP95106213A patent/EP0668268A3/en not_active Withdrawn
- 1991-01-30 US US07/768,074 patent/US5185344A/en not_active Expired - Lifetime
- 1991-01-30 AU AU71866/91A patent/AU627399B2/en not_active Ceased
- 1991-01-30 ES ES91903619T patent/ES2083568T3/es not_active Expired - Lifetime
- 1991-01-30 DE DE69114778T patent/DE69114778T2/de not_active Expired - Fee Related
- 1991-01-30 DK DK91903619.4T patent/DK0466933T3/da active
- 1991-01-30 EP EP91903619A patent/EP0466933B1/en not_active Expired - Lifetime
1995
- 1995-06-28 HU HU95P/P00503P patent/HU211635A9/hu unknown
- 1995-11-29 GR GR950403354T patent/GR3018235T3/el unknown

Also Published As

Publication number	Publication date
AU627399B2 (en)	1992-08-20
EP0466933B1 (en)	1995-11-22
EP0668268A3 (en)	1995-08-30
DE69114778D1 (de)	1996-01-04
EP0466933A4 (en)	1992-07-08
EP0668268A2 (en)	1995-08-23
CA2050587A1 (en)	1991-08-03
CA2050587C (en)	1997-11-25
ES2083568T3 (es)	1996-04-16
EP0466933A1 (en)	1992-01-22
JP2676170B2 (ja)	1997-11-12
WO1991011434A1 (en)	1991-08-08
ATE130605T1 (de)	1995-12-15
KR920701154A (ko)	1992-08-11
KR940004059B1 (ko)	1994-05-11
HU211635A9 (en)	1995-12-28
US5185344A (en)	1993-02-09
GR3018235T3 (en)	1996-02-29
DE69114778T2 (de)	1996-04-18
AU7186691A (en)	1991-08-21

Publication	Publication Date	Title
EP0429685A4 (en)	1991-12-04	Oxoindole derivative
FI911443A0 (fi)	1991-03-25	Foerfarande foer framstaellning av 3,5-di-tert.butyl-4-hydroxifenylmetylenderivat av 2-substituerade tiazolidinoner, oxazolidinoner och imidazolidinoner med antiinflammatorisk aktivitet.
ATE179173T1 (de)	1999-05-15	2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy 1,3-propandiol-derivate
EP0525197A4 (en)	1993-04-07	3-benzylidene-1-carbamoyl-2-pyrrolidone analog
NZ330656A (en)	1999-06-29	Tricyclic compounds, their production and use
NZ260159A (en)	1995-01-27	N-bicyclic nitrogen compounds and medicaments
CA2048067A1 (en)	1992-02-01	Method for recycling discolored polyolefins
DK592688A (da)	1989-04-27	Benz(thi)amidderivater, deres fremstilling og anvendelse som fungicider
DE69114778D1 (de)	1996-01-04	Bicyclolactamderivat.
FI923470A0 (fi)	1992-07-31	Aminokarboxylatligander med substituerade amidgrupper.
DK0566175T3 (da)	1998-01-26	3,4-diaryl-(5H)-furan-2-on-baserede forbindelser med fungicid aktivitet
ES2074992T3 (es)	1995-10-01	Derivados fungicidas de azolilo.
DK0625520T3 (da)	2000-01-31	Thiazolotriazol- og thiazolodiazolderivater med fungicid aktivitet
AU4830890A (en)	1990-08-01	Diazabicycloalkane derivatives
DE69004138D1 (de)	1993-12-02	Mit einer Cyanogruppe substituierte Nitroanilin-Farbstoffe.