DK0471030T3 - Glycoproteinhormonreceptormolekyler - Google Patents

Glycoproteinhormonreceptormolekyler

Info

Publication number
DK0471030T3
DK0471030T3 DK90908349.5T DK90908349T DK0471030T3 DK 0471030 T3 DK0471030 T3 DK 0471030T3 DK 90908349 T DK90908349 T DK 90908349T DK 0471030 T3 DK0471030 T3 DK 0471030T3
Authority
DK
Denmark
Prior art keywords
hormone receptor
receptor molecules
glycoprotein hormone
molecules
stimulating hormone
Prior art date
Application number
DK90908349.5T
Other languages
Danish (da)
English (en)
Inventor
Karoly Nikolics
Keith C Mcfarland
Deborah L Segaloff
Peter H Seeburg
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Application granted granted Critical
Publication of DK0471030T3 publication Critical patent/DK0471030T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2869Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against hormone receptors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/10Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
    • A61P5/12Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH for decreasing, blocking or antagonising the activity of the posterior pituitary hormones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/723G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Diabetes (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Plant Pathology (AREA)
  • Toxicology (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Neurology (AREA)
  • Reproductive Health (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK90908349.5T 1989-05-05 1990-05-04 Glycoproteinhormonreceptormolekyler DK0471030T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US34768389A 1989-05-05 1989-05-05

Publications (1)

Publication Number Publication Date
DK0471030T3 true DK0471030T3 (da) 1995-05-29

Family

ID=23364795

Family Applications (2)

Application Number Title Priority Date Filing Date
DK90908349.5T DK0471030T3 (da) 1989-05-05 1990-05-04 Glycoproteinhormonreceptormolekyler
DK94104166T DK0614975T3 (da) 1989-05-05 1990-05-04 Glycoproteinhormonreceptormolekyler

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK94104166T DK0614975T3 (da) 1989-05-05 1990-05-04 Glycoproteinhormonreceptormolekyler

Country Status (9)

Country Link
EP (3) EP0614975B1 (de)
JP (1) JPH04505103A (de)
AT (2) ATE221123T1 (de)
AU (1) AU5732190A (de)
DE (2) DE69015175T2 (de)
DK (2) DK0471030T3 (de)
ES (2) ES2180550T3 (de)
HK (1) HK1046429A1 (de)
WO (1) WO1990013643A2 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991003483A1 (en) * 1989-09-08 1991-03-21 New England Medical Center Hospitals, Inc. Tsh receptor
US5614363A (en) * 1990-01-25 1997-03-25 New England Medical Center Hospitals, Inc. TSH receptor
JPH05504683A (ja) * 1989-12-20 1993-07-22 ニコルス インスティテュート ダイアグノスティックス 組み換えチロトロピン受容体
EP0475292B1 (de) * 1990-09-10 1999-06-30 Takeda Chemical Industries, Ltd. Menschlicher Rezeptor für luteinisierendes Hormon und Choriongonadotropin
CA2106061C (en) * 1991-03-15 2008-10-07 Christie A. Kelton Human follicle stimulating hormone receptor
AU3949893A (en) * 1992-03-30 1993-11-08 Akzo Nobel N.V. Human gonadotropin receptor (FSH receptor)
US6033903A (en) * 1995-06-02 2000-03-07 Applied Research Systems, ARS Holding N.V. Method of expressing and secreting soluble extracellular domains of human gonadotropin hormone receptors
US5925549A (en) * 1996-04-15 1999-07-20 The Board Of Trustees Of The Leland Stanford Junior University Soluble 7-transmembrane domain G-protein-coupled receptor compositions and methods
US5858716A (en) * 1997-05-30 1999-01-12 Smithkline Beecham Corporation H2CAA71 polynucleotides
WO1999036530A2 (en) * 1998-01-20 1999-07-22 Wilex Biotechnology Gmbh Lh-receptor gene promoter for tissue-specific gene expression
GB9909661D0 (en) 1998-06-06 1999-06-23 Rsr Ltd Assays for TSH receptor autoantibodies
EP1456234B1 (de) 2001-08-23 2014-04-09 Rsr Limited Epitop-regionen des thyrotrophin (tsh) rezeptors, verwendungen davon und antikörper dagegen

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4560649A (en) * 1981-10-15 1985-12-24 Cornell Research Foundation Assaying for hLH or hCG with immobilized hormone receptors
US4761371A (en) * 1985-02-12 1988-08-02 Genentech, Inc. Insulin receptor
US4921808A (en) * 1986-06-25 1990-05-01 The Albany Medical College Of Union University Method for determining follicle stimulating hormone
WO1991003483A1 (en) * 1989-09-08 1991-03-21 New England Medical Center Hospitals, Inc. Tsh receptor
EP0433509B1 (de) * 1989-12-14 1996-11-13 B.R.A.H.M.S Diagnostica GmbH Polypeptide mit Thyrotropinrezeptor-Aktivität, kodierende Nukleinsäuresequenzen für solche Rezeptoren und Verwendung dieser Polypeptide
JPH05504683A (ja) * 1989-12-20 1993-07-22 ニコルス インスティテュート ダイアグノスティックス 組み換えチロトロピン受容体
FR2657014A1 (fr) * 1990-01-15 1991-07-19 Inst Nat Sante Rech Med Recepteur humain de la tsh. sequence codant pour ce recepteur.

Also Published As

Publication number Publication date
ES2068388T3 (es) 1995-04-16
WO1990013643A2 (en) 1990-11-15
EP1199361A3 (de) 2004-03-10
JPH04505103A (ja) 1992-09-10
DE69015175T2 (de) 1995-06-29
EP0471030A1 (de) 1992-02-19
ATE221123T1 (de) 2002-08-15
DE69033990D1 (de) 2002-08-29
DE69015175D1 (de) 1995-01-26
EP0614975B1 (de) 2002-07-24
ATE115409T1 (de) 1994-12-15
EP0471030B1 (de) 1994-12-14
EP0614975A1 (de) 1994-09-14
ES2180550T3 (es) 2003-02-16
WO1990013643A3 (en) 1991-01-10
EP1199361A2 (de) 2002-04-24
HK1046429A1 (en) 2003-01-10
DK0614975T3 (da) 2002-11-11
AU5732190A (en) 1990-11-29
DE69033990T2 (de) 2003-02-13

Similar Documents

Publication Publication Date Title
EP0236684A3 (en) Galanthamine or analogues thereof for treating alzheimer's disease
DK0605442T3 (da) Rekombinante antistoffer til human terapi
GR3030141T3 (en) Diphtheria toxin receptor-binding region.
FI851336A0 (fi) Ny fysiologiskt aktiv human polypeptid.
ATE358176T1 (de) Menschliche dnase
DK143492A (da) Human-h2-praeprorelaxin, -prorelaxin og -relaxin samt polypeptid med relaxinaktivitet
DK0471030T3 (da) Glycoproteinhormonreceptormolekyler
IL110672A0 (en) Therapeutic heterocycles
DK0669979T3 (da) C-C CKR-1, kemokinreceptor
ZA896558B (en) Method of treating skin injuries using thromboxane a2 receptor antagonists
ES2059545T5 (es) Hormonas de glicoproteinas modificadas por mutagenesis dirigida por puntos y metodos de uso de tales hormonas.
ATE199167T1 (de) Nichtglykosyliertes fgf-4 und dieses enthaltende präparate
ES548617A0 (es) Procedimiento para disociar peptidos y proteinas en el enla-ce metionilo
EE05497B1 (et) Polüpeptiid, lahustuv CRAM-1 polüpeptiid, polünukleotiid ja antikeha
IT8619055A0 (it) Composizioni farmaceutiche comprendenti peptidi del gruppo colecistochinina-cerulina per il trattamento terapeutico degli statidi shock e dell'insufficienza respiratoria e cardiocircolatoria.
EP0209543A4 (de) Peptidfragmente menschlicher apolipoproteine, typspezifische antikörper und verwendungsverfahren.
DE69010294D1 (de) Verwendung von Antiprogestomimetika zur Stimulierung des Eisprungs.
DE3886517D1 (de) Menschlicher Prourokinase ähnliches Polypeptid.
ES2076141T3 (es) 5-aril-3h-1,2,4-triazol-3-onas y su uso como anticonvulsivos.
IT8620548A0 (it) Procedimento e dispositivo per la fabbricazione di prodotti in fibra di vetro, per esempio veli, feltri, filati e stoppini.
IT8619086A0 (it) Composizioni farmaceutiche comprendenti frammenti di acth per il trattamento terapeutico degli stati di shock e dell'insufficienza respiratoria e cardiocircolatoria.
NZ220242A (en) Regulating fertility in cattle by administering epostane
王殿洪 et al. PURIFICATION AND CHARACTERIZATION OF INSULIN RECEPTORS FROM HUMAN PLACENTA
ATE98990T1 (de) Menschlicher prourokinase aehnliches polypeptid.
IT8804860A0 (it) Procedimento per il recupero di calore, con eventuale recupero od uso dell'umidita', ceduto direttamente o indirettamente dal corpo umano e dispositivo per la sua attuazione.