DK0474597T3 - Diphenylforbindelser med inhiberende virkning på arachidonsyrestofskiftet og deres anvendelse i farmaceutiske præparater - Google Patents

Diphenylforbindelser med inhiberende virkning på arachidonsyrestofskiftet og deres anvendelse i farmaceutiske præparater

Info

Publication number: DK0474597T3
Authority: DK; Denmark
Prior art keywords: inhibitory effect; pharmaceutical preparations; arachidonic acid; acid metabolism; diphenyl compounds
Prior art date: 1990-09-05

Application number

DK91810685.7T

Other languages

Danish (da)

English (en)

Inventor

Tankred Prof Dr Schewe

Helmut Dr Luther

Dentscho Dr Jordanov

Original Assignee

Ciba Geigy Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-09-05

Filing date

1991-08-27

Publication date

1997-10-20

1991-08-27 Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag

1997-10-20 Application granted granted Critical

1997-10-20 Publication of DK0474597T3 publication Critical patent/DK0474597T3/da

Links

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/075—Ethers or acetals
- A61K31/085—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/065—Diphenyl-substituted acyclic alcohols
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/05—Phenols
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/05—Phenols
- A61K31/055—Phenols the aromatic ring being substituted by halogen
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/05—Phenols
- A61K31/06—Phenols the aromatic ring being substituted by nitro groups
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
- A61K31/10—Sulfides; Sulfoxides; Sulfones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Epidemiology (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pulmonology (AREA)
Pain & Pain Management (AREA)
Dermatology (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Oncology (AREA)
Neurosurgery (AREA)
Rheumatology (AREA)
Communicable Diseases (AREA)
Immunology (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Medicinal Preparation (AREA)
Medicines Containing Plant Substances (AREA)

DK91810685.7T 1990-09-05 1991-08-27 Diphenylforbindelser med inhiberende virkning på arachidonsyrestofskiftet og deres anvendelse i farmaceutiske præparater DK0474597T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
CH287590		1990-09-05

Publications (1)

Publication Number	Publication Date
DK0474597T3 true DK0474597T3 (da)	1997-10-20

Family

ID=4243541

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK91810685.7T DK0474597T3 (da)	1990-09-05	1991-08-27	Diphenylforbindelser med inhiberende virkning på arachidonsyrestofskiftet og deres anvendelse i farmaceutiske præparater

Country Status (22)

Country	Link
US (1)	US5185377A (cs)
EP (1)	EP0474597B1 (cs)
JP (1)	JP3264950B2 (cs)
KR (1)	KR100201749B1 (cs)
AT (1)	ATE156353T1 (cs)
AU (1)	AU645599B2 (cs)
CA (1)	CA2050569C (cs)
CZ (1)	CZ279624B6 (cs)
DE (1)	DE59108814D1 (cs)
DK (1)	DK0474597T3 (cs)
ES (1)	ES2106770T3 (cs)
FI (1)	FI914185A7 (cs)
GR (1)	GR3024440T3 (cs)
HU (2)	HUT58998A (cs)
IE (1)	IE913110A1 (cs)
IL (1)	IL99376A (cs)
MX (1)	MX9100917A (cs)
NO (1)	NO913472L (cs)
PT (1)	PT98874B (cs)
RU (1)	RU2060731C1 (cs)
SK (1)	SK279104B6 (cs)
ZA (1)	ZA917005B (cs)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9117140D0 (en) *	1991-08-08	1991-09-25	Unilever Plc	Treatment of periodontitis
US6440395B1 (en)	1992-06-22	2002-08-27	Barry M. Libin	Antiplaque mouth rinse
CH686285A5 (fr) *	1992-08-06	1996-02-29	Beiersdorf Ag	Preparation cosmetique ou pharmaceutique servant a retarder le vieillissement de la peau humaine.
US5880146A (en) *	1995-06-07	1999-03-09	Fuji Immunopharmaceuticals Corporation	Inhibition of IL-12-induced IFN-γ synthesis by specific bis-phenol compounds as a method of immune modulation
EP0839031A1 (de) *	1995-07-20	1998-05-06	JUERGENS, Uwe R.	Verwendung eines nicht-steroidalen antiphlogistikums zur topischen und systemischen behandlung der akuten und chronischen polypoiden rhinosinusitis
AUPN814496A0 (en) *	1996-02-19	1996-03-14	Monash University	Dermal penetration enhancer
US6108850A (en) *	1997-06-03	2000-08-29	Mclaughlin; Gerald	Accelerated method and instrumentation for whitening teeth
DE19834355A1 (de) *	1998-07-30	2000-02-03	Henkel Kgaa	Entzündungshemmende Zahnpflegemittel
US7566740B2 (en) *	1998-10-06	2009-07-28	Bml Pharmaceuticals, Inc.	Method of treating mucositis
WO2001000138A2 (en) *	1999-06-23	2001-01-04	Jawaharlal Nehru Centre For Advanced Scientific Research	Use of hydroxydiphenyl ether class of chemicals, as exemplified by triclosan, as an antimalarial and identification of fatty acid synthesis as its target
RU2200550C2 (ru) *	1999-10-29	2003-03-20	Научно-исследовательская лаборатория иммунохимиотерапии лепры и иммунотропных средств с клиникой и опытно-экспериментальным производством	Новые лекарственные формы димоцифона в терапии лепры, зудящих и аллергодерматозов, герпетиформного дерматита дюринга
WO2002050008A2 (en) *	2000-12-20	2002-06-27	Warner-Lambert Company Llc	Non-halogenated phenoxy and/or benzyloxy phenols and antimicrobial compositions containing them
EP1366763A1 (en) *	2002-05-28	2003-12-03	Ciba SC Holding AG	Hydroxy diphenyl ether compounds as anti-inflammatory agents
US20030229149A1 (en) *	2002-05-28	2003-12-11	Werner Baschong	Anti-inflammatory agents
JP2013532734A (ja) *	2010-08-04	2013-08-19	ユニバーシティオブバージニアパテントファウンデーション	炎症性疾患を治療するための組成物及び方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA1199273A (en) *	1982-07-15	1986-01-14	Ctibor Schindlery	Anti-inflammatory composition
GB2148116B (en) *	1983-10-27	1986-07-30	Ciba Geigy Ag	Topical steroid preparations
GB8526093D0 (en) *	1985-10-22	1985-11-27	Beecham Group Plc	Composition
US4735802A (en) *	1986-05-05	1988-04-05	Le Bich N	Topical dermatological composition and method of treatment
US4942029A (en) *	1986-09-19	1990-07-17	Smith & Nephew United, Inc.	Medicated skin preparation
GB8629640D0 (en) *	1986-12-11	1987-01-21	Beecham Group Plc	Composition & method
GB8718026D0 (en) *	1987-07-29	1987-09-03	Smith & Nephew Ass	Pharmaceutical composition
AU610906B2 (en) *	1987-07-31	1991-05-30	Sumitomo Chemical Company, Limited	Method for preventing harm from bloodsucking insects

1991
- 1991-08-27 AT AT91810685T patent/ATE156353T1/de not_active IP Right Cessation
- 1991-08-27 DK DK91810685.7T patent/DK0474597T3/da active
- 1991-08-27 ES ES91810685T patent/ES2106770T3/es not_active Expired - Lifetime
- 1991-08-27 EP EP91810685A patent/EP0474597B1/de not_active Expired - Lifetime
- 1991-08-27 DE DE59108814T patent/DE59108814D1/de not_active Expired - Lifetime
- 1991-09-03 MX MX9100917A patent/MX9100917A/es not_active IP Right Cessation
- 1991-09-03 CA CA002050569A patent/CA2050569C/en not_active Expired - Lifetime
- 1991-09-03 IL IL9937691A patent/IL99376A/en not_active IP Right Cessation
- 1991-09-04 NO NO91913472A patent/NO913472L/no unknown
- 1991-09-04 HU HU912866A patent/HUT58998A/hu unknown
- 1991-09-04 ZA ZA917005A patent/ZA917005B/xx unknown
- 1991-09-04 US US07/754,788 patent/US5185377A/en not_active Expired - Lifetime
- 1991-09-04 KR KR1019910015407A patent/KR100201749B1/ko not_active Expired - Fee Related
- 1991-09-04 RU SU915001448A patent/RU2060731C1/ru active
- 1991-09-04 FI FI914185A patent/FI914185A7/fi unknown
- 1991-09-04 SK SK2718-91A patent/SK279104B6/sk unknown
- 1991-09-04 CZ CS912718A patent/CZ279624B6/cs unknown
- 1991-09-04 IE IE311091A patent/IE913110A1/en not_active IP Right Cessation
- 1991-09-04 AU AU83640/91A patent/AU645599B2/en not_active Ceased
- 1991-09-05 JP JP22563191A patent/JP3264950B2/ja not_active Expired - Lifetime
- 1991-09-05 PT PT98874A patent/PT98874B/pt not_active IP Right Cessation
1995
- 1995-06-21 HU HU95P/P00310P patent/HU211292A9/hu unknown
1997
- 1997-08-13 GR GR970402083T patent/GR3024440T3/el unknown

Also Published As

Publication number	Publication date
PT98874A (pt)	1992-07-31
JPH04257517A (ja)	1992-09-11
PT98874B (pt)	1999-02-26
AU645599B2 (en)	1994-01-20
IE913110A1 (en)	1992-03-11
EP0474597B1 (de)	1997-08-06
KR100201749B1 (ko)	1999-06-15
CS271891A3 (en)	1992-03-18
IL99376A0 (en)	1992-08-18
MX9100917A (es)	1992-05-04
SK279104B6 (sk)	1998-06-03
CA2050569C (en)	2004-01-27
US5185377A (en)	1993-02-09
EP0474597A2 (de)	1992-03-11
IL99376A (en)	1996-01-19
HUT58998A (en)	1992-04-28
NO913472D0 (no)	1991-09-04
HU211292A9 (en)	1995-11-28
NO913472L (no)	1992-03-06
FI914185A0 (fi)	1991-09-04
ATE156353T1 (de)	1997-08-15
KR920005988A (ko)	1992-04-27
AU8364091A (en)	1992-03-12
JP3264950B2 (ja)	2002-03-11
CZ279624B6 (cs)	1995-05-17
ES2106770T3 (es)	1997-11-16
CA2050569A1 (en)	1992-03-06
RU2060731C1 (ru)	1996-05-27
EP0474597A3 (en)	1992-07-01
ZA917005B (en)	1992-04-29
FI914185A7 (fi)	1992-03-06
GR3024440T3 (en)	1997-11-28
DE59108814D1 (de)	1997-09-11

Publication	Publication Date	Title
AU645599B2 (en)	1994-01-20	Diphenyl compounds which inhibit arachidonic acid metabolism, and their use in pharmaceutical compositions
SE8804036D0 (sv)	1988-11-08	New use of 11,28-dioxa-4-azatricyclo(22.3.1.0?724,9 )octacos-18-ene derivatives and pharmaceutical compositions containing them
BR9810385A (pt)	2000-09-05	Derivados de ácido benzóico 2-(4-bromo ou 4-iodo fenilamino) e sua utilização como inibidores de mek
DK0559743T3 (da)	1995-07-03	Nye hydroxamsyre- og N-hydroxyurinstofderivater og deres anvendelse
DK0529568T3 (da)	1997-02-03	Nye oralt aktive elastaseinhibitorer
ATE47999T1 (de)	1989-12-15	2-amino-5-hydroxy-4-methylpyrimidin-derivate.
NO922111L (no)	1992-11-30	Rapamycin-dimerer
SE0302324D0 (sv)	2003-08-28	Novel compounds
SE0302323D0 (sv)	2003-08-28	Novel compounds
NO924045L (no)	1992-10-19	Anti-inflammatoriske hydroksamsyrer og n-hydroksyurinstoffer
DK513384D0 (da)	1984-10-26	Griseolsyrederivater og deres anvendelse
ECSP055844A (es)	2005-09-20	Nuevos compuestos triciclicos
ES2193196T3 (es)	2003-11-01	Derivados de dieteres de catecol como agentes farmaceuticos.
ES2063578T3 (es)	1995-01-01	Derivados del acido hidroxamico y de n-hidroxiurea inhibidores de la lipoxigenasa.
MX2025002985A (es)	2025-05-02	Compuestos para el tratamiento de procesos inflamatorios
CO4230229A1 (es)	1995-10-19	Fenoxifenil ciclopentenil hidroxiureas
BR0314714A (pt)	2005-08-02	Compostos para o tratamento da doença de alzheimer
IT1247093B (it)	1994-12-12	Derivati salini del gliceril fosforil mioinositolo ad attivita' terapeutica, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono
ES8307803A1 (es)	1983-08-01	Procedimiento de preparar trimetoxibenzoatos de apovincaminol substituidos con efecto inhibidor de las fosfodiestebasas.
FI851617L (fi)	1985-10-26	Triazolopyrimidinderivat.
ES8707233A1 (es)	1987-07-16	Un procedimiento para preparar derivados de piridina
ES2056211T3 (es)	1994-10-01	Derivados de acilsulfonamida de acidos alfa-carbocicliltoluicos usados como antagonistas de leucotrienos.