DK0478702T3 - Indkapslingsproces - Google Patents

Indkapslingsproces

Info

Publication number: DK0478702T3
Authority: DK; Denmark
Prior art keywords: encapsulation; liposomes; osmolarity; oligonucleotides; oligonucleotide
Prior art date: 1989-06-22

Application number

DK90912475.2T

Other languages

English (en)

Inventor

Sean M Sullivan

Original Assignee

Nexstar Pharmaceuticals Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-06-22

Filing date

1990-06-20

Publication date

1995-02-13

1990-06-20 Application filed by Nexstar Pharmaceuticals Inc filed Critical Nexstar Pharmaceuticals Inc

1995-02-13 Application granted granted Critical

1995-02-13 Publication of DK0478702T3 publication Critical patent/DK0478702T3/da

Links

238000005538 encapsulation Methods 0.000 title abstract 2
108091034117 Oligonucleotide Proteins 0.000 abstract 2
239000002502 liposome Substances 0.000 abstract 2
JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 abstract 1
239000008346 aqueous phase Substances 0.000 abstract 1
150000001768 cations Chemical class 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1277—Preparation processes; Proliposomes
- A61K9/1278—Post-loading, e.g. by ion or pH gradient

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Dispersion Chemistry (AREA)
Molecular Biology (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Glass Compositions (AREA)
Manufacturing Of Micro-Capsules (AREA)
Superconductors And Manufacturing Methods Therefor (AREA)
Separation By Low-Temperature Treatments (AREA)
Extrusion Moulding Of Plastics Or The Like (AREA)
Surgical Instruments (AREA)

DK90912475.2T 1989-06-22 1990-06-20 Indkapslingsproces DK0478702T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US36971289A	1989-06-22	1989-06-22

Publications (1)

Publication Number	Publication Date
DK0478702T3 true DK0478702T3 (da)	1995-02-13

Family

ID=23456592

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK90912475.2T DK0478702T3 (da)	1989-06-22	1990-06-20	Indkapslingsproces

Country Status (9)

Country	Link
EP (1)	EP0478702B1 (da)
JP (1)	JP2880800B2 (da)
AT (1)	ATE114967T1 (da)
AU (1)	AU638271B2 (da)
CA (1)	CA2059129C (da)
DE (1)	DE69014885T2 (da)
DK (1)	DK0478702T3 (da)
ES (1)	ES2067755T3 (da)
WO (1)	WO1990015595A1 (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5641484A (en) *	1990-12-04	1997-06-24	Board Of Regents, The University Of Texas System	Methods for the suppression of neu mediated tumors by adenoviral E1A and SV40 large T antigen
EP0560932B1 (en) *	1990-12-04	1996-09-04	The Board Of Regents, The University Of Texas System	Methods and compositions for the suppression of neu mediated transformation
US5643567A (en) *	1990-12-04	1997-07-01	Board Of Regents, The University Of Texas System	Methods for the suppression of neu mediated tumors by adenoviral E1A and SV40 large T antigen
JPH06511470A (ja) *	1991-07-03	1994-12-22	ネクスター・フアーマシユーテイカルズ・インコーポレイテツド	薬剤を含むリポソームの調製における充填技術
US5714163A (en) *	1994-06-27	1998-02-03	Nexstar Pharmaceuticals, Inc.	Vinca alkaloid vesicles with enhanced efficacy and tumor targeting properties
US6326356B1 (en)	1996-10-18	2001-12-04	Board Of Regents, The University Of Texas System	Suppression of neu overexpression using a mini-E1A gene
US6395712B1 (en)	1996-03-20	2002-05-28	Board Of Regents, The University Of Texas System	Sensitization of HER-2/neu overexpressing cancer cells to chemotherapy
US6120800A (en) *	1997-09-25	2000-09-19	Nexstar Pharmaceuticals, Inc.	Vinca-alkaloid vesicles with enhanced efficacy and tumor targeting properties
US6289229B1 (en)	1998-01-20	2001-09-11	Scimed Life Systems, Inc.	Readable probe array for in vivo use
US6153217A (en) *	1999-01-22	2000-11-28	Biodelivery Sciences, Inc.	Nanocochleate formulations, process of preparation and method of delivery of pharmaceutical agents
CA2462376C (en) *	2001-10-03	2010-12-14	Celator Technologies Inc.	Liposome loading with metal ions
DE60222580T2 (de) *	2001-11-13	2008-06-12	Celator Pharmaceuticals, Inc.	Lipidträgerzusammensetzungen und verfahren zur verbesserten wirkstoffzurückhaltung
AU2016256979B2 (en)	2015-05-04	2021-01-28	Genfit	Method for preparing transmembrane pH-gradient vesicles

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0061253A3 (en) *	1981-03-18	1982-12-08	Beecham Group Plc	Process for the transfer of genetic material into actinomycete cells, prepared cells and method of culturing these cells and isolating a metabolite
US4532089A (en) *	1984-01-14	1985-07-30	Northwestern University	Method of preparing giant size liposomes
CA1270198A (en) *	1984-08-08	1990-06-12	Marcel B. Bally	Encapsulation of antineoplastic agents in liposomes
JPS6176414A (ja) *	1984-09-21	1986-04-18	Shionogi & Co Ltd	リポソーム製剤の製法
US5049392A (en) *	1989-01-18	1991-09-17	The Liposome Company, Inc.	Osmotically dependent vesicles

1990
- 1990-06-20 AT AT90912475T patent/ATE114967T1/de not_active IP Right Cessation
- 1990-06-20 ES ES90912475T patent/ES2067755T3/es not_active Expired - Lifetime
- 1990-06-20 AU AU61824/90A patent/AU638271B2/en not_active Expired
- 1990-06-20 CA CA002059129A patent/CA2059129C/en not_active Expired - Lifetime
- 1990-06-20 EP EP90912475A patent/EP0478702B1/en not_active Expired - Lifetime
- 1990-06-20 WO PCT/US1990/003477 patent/WO1990015595A1/en not_active Ceased
- 1990-06-20 JP JP2511838A patent/JP2880800B2/ja not_active Expired - Lifetime
- 1990-06-20 DE DE69014885T patent/DE69014885T2/de not_active Expired - Lifetime
- 1990-06-20 DK DK90912475.2T patent/DK0478702T3/da active

Also Published As

Publication number	Publication date
EP0478702A1 (en)	1992-04-08
ES2067755T3 (es)	1995-04-01
DE69014885T2 (de)	1995-04-27
ATE114967T1 (de)	1994-12-15
WO1990015595A1 (en)	1990-12-27
AU638271B2 (en)	1993-06-24
CA2059129C (en)	1996-07-02
DE69014885D1 (de)	1995-01-19
AU6182490A (en)	1991-01-08
JP2880800B2 (ja)	1999-04-12
CA2059129A1 (en)	1990-12-23
EP0478702B1 (en)	1994-12-07
JPH04506355A (ja)	1992-11-05
EP0478702A4 (en)	1992-07-08

Publication	Publication Date	Title
DK0478702T3 (da)	1995-02-13	Indkapslingsproces
KR900012578A (ko)	1990-09-01	외과용 비누 분배기 콘테이너
DE69011300D1 (de)	1994-09-08	Alkylierungsverfahren.
PT91440A (pt)	1990-03-08	Processo para a preparacao de agentes anti-fungicos de triazole
DE3786777D1 (de)	1993-09-02	Vorrichtung zum herstellen von beipackzetteln.
BR8803767A (pt)	1989-02-21	Processo para esterilizacao com vapor
DE68904785D1 (de)	1993-03-25	Behaelter fuer prozessloesung.
DE69005177D1 (de)	1994-01-27	Vorrichtung zur Herstellung von Aufhängeverpackungen.
DE3677520D1 (de)	1991-03-14	Vorrichtung zur behandlung von behaeltern.
BR8802066A (pt)	1988-11-29	Processo para preparacao de azois n-substituidos,especialmente imidazois n-substituidos
IT8748428A0 (it)	1987-09-28	Procedimento per la formazione di contenitori,in particolare lattine
TR24465A (tr)	1991-11-01	Zeolit topaklama islemi ve mamulue
IT8748057A0 (it)	1987-06-15	Valvola di iniezione elettromagneti ca intermittente
DK125588D0 (da)	1988-03-09	Mikroboelgesterilisator
BR9000986A (pt)	1991-02-19	Mistura esterilizante e processo para esterilizar um artigo
PT90176A (pt)	1989-11-10	Processo para a preparacao de um agente de tratamento de gado equideo
FI891624A7 (fi)	1989-11-12	Menetelmä 0-substituoitujen hydroksyyliamiinien valmistamiseksi
BR8804959A (pt)	1990-05-15	Processo e aparelho para curar artigos de paredes espressas
FI894850A7 (fi)	1989-10-13	Jäähdytetty säiliökontti
IT8921957A0 (it)	1989-10-09	Macchina per il trattamento di recipienti
FI901709A7 (fi)	1991-10-05	Menetelmä tyydyttymättömien aminodikarboksyylihappojohdannaisten valmistamiseksi
IT8748697A0 (it)	1987-12-11	Macchina per trattare recipienti, in particolare macchina di riempimento
FR2608926B1 (fr)	1990-07-06	Antigene de babesia divergens, procede pour le produire et vaccin le contenant
DK235489D0 (da)	1989-05-12	Mikroboelge- emballagesteriliseringsanlaeg
DK161389D0 (da)	1989-04-04	Flaskeemballage