DK0480052T3 - Quinolinderivat, antiulcus-lægemiddel indeholdende derivatet og fremstilling af derivatet - Google Patents

Quinolinderivat, antiulcus-lægemiddel indeholdende derivatet og fremstilling af derivatet

Info

Publication number
DK0480052T3
DK0480052T3 DK91906582.1T DK91906582T DK0480052T3 DK 0480052 T3 DK0480052 T3 DK 0480052T3 DK 91906582 T DK91906582 T DK 91906582T DK 0480052 T3 DK0480052 T3 DK 0480052T3
Authority
DK
Denmark
Prior art keywords
derivative
antiulcus
preparation
quinoline
drug containing
Prior art date
Application number
DK91906582.1T
Other languages
English (en)
Inventor
Minoru Uchida
Seiji Morita
Kenji Otsubo
Takefumi Shimizu
Katsuya Yamasaki
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Application granted granted Critical
Publication of DK0480052T3 publication Critical patent/DK0480052T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
DK91906582.1T 1990-03-28 1991-03-27 Quinolinderivat, antiulcus-lægemiddel indeholdende derivatet og fremstilling af derivatet DK0480052T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP8177390 1990-03-28

Publications (1)

Publication Number Publication Date
DK0480052T3 true DK0480052T3 (da) 1998-05-11

Family

ID=13755797

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91906582.1T DK0480052T3 (da) 1990-03-28 1991-03-27 Quinolinderivat, antiulcus-lægemiddel indeholdende derivatet og fremstilling af derivatet

Country Status (9)

Country Link
US (1) US5215999A (da)
EP (1) EP0480052B1 (da)
JP (1) JPH04211661A (da)
KR (1) KR920701162A (da)
AU (1) AU634880B2 (da)
DE (1) DE69128682T2 (da)
DK (1) DK0480052T3 (da)
ES (1) ES2112272T3 (da)
WO (1) WO1991014677A1 (da)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5556863A (en) * 1993-06-11 1996-09-17 Astra Aktiebolag Compound for gastric acid secretion inhibition
IS4164A (is) * 1993-06-11 1994-12-12 Ab Astra Efnasambönd sem hindra flæði magasýru
ATE197146T1 (de) * 1993-08-10 2000-11-15 Black James Foundation Gastrin-und cck-rezeptorligande
EP0887340A4 (en) * 1996-02-06 2000-03-29 Japan Tobacco Inc CHEMICAL COMPOUNDS AND THEIR PHARMACEUTICAL USE
JP2001524468A (ja) * 1997-11-21 2001-12-04 エヌピーエス ファーマシューティカルズ インコーポレーテッド 中枢神経系疾患を治療するための代謝調節型グルタミン酸受容体アンタゴニスト
US20020058734A1 (en) * 2000-09-01 2002-05-16 Harlan C. Wayne Asphalt emulsion
US6576644B2 (en) 2000-09-06 2003-06-10 Bristol-Myers Squibb Co. Quinoline inhibitors of cGMP phosphodiesterase
US7067532B2 (en) * 2000-11-02 2006-06-27 Astrazeneca Substituted quinolines as antitumor agents
UA80393C2 (uk) 2000-12-07 2007-09-25 Алтана Фарма Аг Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці
US20020119196A1 (en) * 2000-12-21 2002-08-29 Narendra Parikh Texture masked particles containing an active ingredient
MY140561A (en) 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
TWI314041B (en) * 2002-10-21 2009-09-01 Sankyo Agro Co Ltd Quinolyl-3-carboxamide compound
AU2004220357B2 (en) 2003-03-10 2010-09-30 Astrazeneca Ab Novel process for the preparation of roflumilast
TWI328009B (en) * 2003-05-21 2010-08-01 Glaxo Group Ltd Quinoline derivatives as phosphodiesterase inhibitors
GB0322726D0 (en) * 2003-09-27 2003-10-29 Glaxo Group Ltd Compounds
GB0322722D0 (en) * 2003-09-27 2003-10-29 Glaxo Group Ltd Compounds
SE0400284D0 (sv) * 2004-02-10 2004-02-10 Astrazeneca Ab Novel compounds
ES2421916T3 (es) * 2005-03-16 2013-09-06 Nycomed Gmbh Forma farmacéutica de sabor enmascarado que contiene roflumilast
TW200829555A (en) * 2006-11-10 2008-07-16 Astrazeneca Ab Chemical compounds
CL2008000191A1 (es) * 2007-01-25 2008-08-22 Astrazeneca Ab Compuestos derivados de 4-amino-cinnotina-3-carboxamida; inhibidores de csf-1r quinasa; su proceso de preparacion; y su uso para tratar el cancer.
WO2009136191A1 (en) * 2008-05-07 2009-11-12 Astrazeneca Ab Chemical compounds
US12486234B2 (en) 2019-04-24 2025-12-02 Children's Medical Center Corporation PAPD5 inhibitors and methods of use thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA801526B (en) * 1979-03-26 1981-08-26 Robins Co Inc A H 4-amino-3-quinolinecarboxylic acids and esters-antisecretory, anti-ulcer compounds
FR2467934A1 (fr) * 1979-10-18 1981-04-30 Siplast Soc Nouvelle Materiau de sous-toiture
US4284768A (en) * 1980-07-02 1981-08-18 American Home Products Corporation 1,2-Dihydro-4-amino-2-oxo-3-quinoline-carboxylic acid derivatives
FI80022C (fi) * 1982-07-05 1990-04-10 Otsuka Pharma Co Ltd Foerfarande foer framstaellning av ett nytt, terapeutiskt anvaendbart karbostyrilderivat.
DE3579436D1 (de) * 1984-12-18 1990-10-04 Otsuka Pharma Co Ltd Tetrahydrochinolin- derivate, verfahren zu deren herstellung und diese enthaltende antimagengeschwuerzusammensetzungen.
DE3773240D1 (de) * 1986-03-28 1991-10-31 Otsuka Pharma Co Ltd Hydrochinolinverbindungen, diese enthaltende zusammensetzungen und verfahren zu ihrer herstellung.
GB8621425D0 (en) * 1986-09-05 1986-10-15 Smith Kline French Lab Compounds
GB8804445D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804443D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804444D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
DK273689A (da) * 1988-06-06 1989-12-07 Sanofi Sa 4-amino-3-carboxyquinoliner og -naphthyridiner, fremgangsmaade til deres fremstilling og anvendelse deraf i laegemidler

Also Published As

Publication number Publication date
EP0480052A1 (en) 1992-04-15
DE69128682D1 (de) 1998-02-19
EP0480052B1 (en) 1998-01-14
JPH04211661A (ja) 1992-08-03
AU634880B2 (en) 1993-03-04
DE69128682T2 (de) 1998-06-04
ES2112272T3 (es) 1998-04-01
US5215999A (en) 1993-06-01
KR920701162A (ko) 1992-08-11
WO1991014677A1 (en) 1991-10-03
EP0480052A4 (en) 1992-08-19
AU7548091A (en) 1991-10-21

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