DK0480906T3 - Farmaceutisk tilberedning på basis af Lys-plasminogen - Google Patents

Farmaceutisk tilberedning på basis af Lys-plasminogen

Info

Publication number
DK0480906T3
DK0480906T3 DK91890236.2T DK91890236T DK0480906T3 DK 0480906 T3 DK0480906 T3 DK 0480906T3 DK 91890236 T DK91890236 T DK 91890236T DK 0480906 T3 DK0480906 T3 DK 0480906T3
Authority
DK
Denmark
Prior art keywords
plasminogen
pharmaceutical preparation
lys
preparation based
nmol
Prior art date
Application number
DK91890236.2T
Other languages
English (en)
Inventor
Anton Philapitsch
Hans Peter Dr Schwarz
Johann Dr Eibl
Original Assignee
Immuno Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immuno Ag filed Critical Immuno Ag
Application granted granted Critical
Publication of DK0480906T3 publication Critical patent/DK0480906T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6435—Plasmin (3.4.21.7), i.e. fibrinolysin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21007—Plasmin (3.4.21.7), i.e. fibrinolysin
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/829—Blood
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/829—Blood
    • Y10S530/83—Plasma; serum
    • Y10S530/831—Cohn fractions

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK91890236.2T 1990-10-11 1991-10-07 Farmaceutisk tilberedning på basis af Lys-plasminogen DK0480906T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT0204590A AT402367B (de) 1990-10-11 1990-10-11 Pharmazeutische zubereitung auf basis von lys-plasminogen

Publications (1)

Publication Number Publication Date
DK0480906T3 true DK0480906T3 (da) 1995-10-02

Family

ID=3526585

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91890236.2T DK0480906T3 (da) 1990-10-11 1991-10-07 Farmaceutisk tilberedning på basis af Lys-plasminogen

Country Status (8)

Country Link
US (1) US5304383A (da)
EP (1) EP0480906B1 (da)
JP (1) JP2506521B2 (da)
AT (2) AT402367B (da)
CA (1) CA2053121C (da)
DE (1) DE59105315D1 (da)
DK (1) DK0480906T3 (da)
ES (1) ES2075417T3 (da)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5520912A (en) * 1993-07-02 1996-05-28 Immuno Aktiengesellschaft Prevention and treatment of ischemic events and reperfusion injury resulting therefrom using lys-plasminogen
DE4411143C2 (de) * 1994-03-30 1996-08-01 Immuno Ag Thrombosemittel
CZ283972B6 (cs) * 1995-05-17 1998-07-15 František Mudr. Trnka Farmaceutický prostředek s modulačním účinkem na zhoubné nádory a jeho použití
GB2318732A (en) 1996-11-01 1998-05-06 Johnson & Johnson Medical Wound healing compositions containing alpha-1-antitrypsin
US6186148B1 (en) 1998-02-04 2001-02-13 Kiyoshi Okada Prevention of posterior capsular opacification
US6969515B2 (en) 1999-11-13 2005-11-29 Talecris Biotherapeutics, Inc. Method of thrombolysis by local delivery of reversibly inactivated acidified plasmin
US7544500B2 (en) * 1999-11-13 2009-06-09 Talecris Biotherapeutics, Inc. Process for the production of a reversibly inactive acidified plasmin composition
US6355243B1 (en) 1999-11-13 2002-03-12 Bayer Corporation Method of thrombolysis by local delivery of active plasmin
US6964764B2 (en) * 1999-11-13 2005-11-15 Talecris Biotherapeutics, Inc. Method of thrombolysis by local delivery of reversibly inactivated acidified plasmin
AT409336B (de) * 1999-12-22 2002-07-25 Baxter Ag Verfahren zur herstellung einer c1-esterase-inhibitor (c1-inh)-hältigen zusammensetzung
CA2662101C (en) 2006-08-28 2015-07-07 Omnio Healer Ab Candidates against infection
AU2007290882B2 (en) * 2006-08-28 2013-02-21 Omnio Healer Ab Novel drug target of preventing and treating periodontal disease, improving healing of periodontal wounds and promoting oral health
UA103771C2 (ru) * 2008-06-04 2013-11-25 Грифолз Терапьютикс Инк. Стрептокиназа, активирующая плазмин, способ и набор для получения плазмина
JP5789521B2 (ja) 2009-03-03 2015-10-07 グリフオルス・セラピユーテイクス・インコーポレーテツドＧｒｉｆｏｌｓ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． プラスミノーゲンを製造するための組成物、方法およびキット；ならびにそれから製造されるプラスミン
NZ597452A (en) 2009-07-10 2013-10-25 Thrombogenics Nv Variants of plasminogen and plasmin
WO2011023805A1 (en) 2009-08-28 2011-03-03 Thrombogenics N.V. Use of plasmin for the treatment of filtration failure after trabeculectomy
CA2823491A1 (en) 2011-01-05 2012-07-12 Thrombogenics Nv Plasminogen and plasmin variants
CA2844644A1 (en) 2011-08-12 2013-02-21 Thrombogenics N.V. Plasminogen and plasmin variants
US9788754B2 (en) * 2014-05-16 2017-10-17 Brainlab Ag Method of managing a brain stroke
TWI801331B (zh) 2015-11-03 2023-05-11 美商波麥堤克生物治療股份有限公司 纖維蛋白溶酶原缺乏症之纖維蛋白溶酶原替代療法
US12011455B2 (en) * 2016-03-17 2024-06-18 Vanderbilt University Enhancing plasmin activity to prevent soft tissue calcification
TWI677348B (zh) 2016-12-15 2019-11-21 大陸商深圳瑞健生命科學研究院有限公司 一種改善心臟病變的方法
TWI750189B (zh) * 2016-12-15 2021-12-21 大陸商深圳瑞健生命科學研究院有限公司 一種治療冠狀動脈粥樣硬化及其併發症的方法
CA3067890A1 (en) * 2017-06-19 2018-12-27 Talengen International Limited Method for regulating and controling glp-1/glp-1r and drug
WO2019074886A1 (en) 2017-10-09 2019-04-18 Terumo Bct Biotechnologies, Llc LYOPHILIZATION CONTAINER AND METHOD OF USE
US11609042B2 (en) 2019-03-14 2023-03-21 Terumo Bct Biotechnologies, Llc Multi-part lyophilization container and method of use

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2347048A2 (fr) * 1976-04-07 1977-11-04 Choay Sa Compositions constituees par des composes du type plasminogene, notamment d'origine placentaire, procede d'obtention des ces compositions, et medicaments contenant ces compositions
JPS597693B2 (ja) * 1978-01-07 1984-02-20 株式会社ミドリ十字 抗トロンビン製剤及びその製法
JPS5716824A (en) * 1980-07-03 1982-01-28 Green Cross Corp:The Plasminogen pharmaceutical and stabilizing method thereof
GB2068002B (en) * 1980-01-25 1983-06-29 Green Cross Corp Plasminogen preparation and their production
DE3119157A1 (de) * 1981-05-14 1982-12-09 Behringwerke Ag, 3550 Marburg Verfahren zur herstellung von und danach hergestelltes plasminogen
GB8721951D0 (en) * 1987-09-18 1987-10-28 Thrombosis Research Trust Organic compounds
AT390801B (de) * 1988-07-28 1990-07-10 Immuno Ag Verfahren zur herstellung von lys-plasminogen
CU22302A1 (es) * 1990-09-07 1995-01-31 Cigb Secuencia nucleotidica codificante para una proteina de la membrana externa de neisseria meningitidis y uso de dicha proteina en preparados vacunales

Also Published As

Publication number Publication date
US5304383A (en) 1994-04-19
JP2506521B2 (ja) 1996-06-12
AT402367B (de) 1997-04-25
ATE121628T1 (de) 1995-05-15
DE59105315D1 (de) 1995-06-01
EP0480906A3 (en) 1992-07-01
ES2075417T3 (es) 1995-10-01
CA2053121A1 (en) 1992-04-12
ATA204590A (de) 1996-09-15
JPH04273827A (ja) 1992-09-30
EP0480906B1 (de) 1995-04-26
EP0480906A2 (de) 1992-04-15
CA2053121C (en) 2000-05-16

Similar Documents

Publication Publication Date Title
ES2075417T3 (es) Preparacion farmaceutica a base de plasminogeno-lys.
AU124792S (en) Bowl
ES2095027T3 (es) Lente de contacto blanda, torica.
DE60134280D1 (de) In vitro rekonstituierte lagen des menschlichen ho
MD306B1 (ro) Remediu pentru profilaxia afectiunilor vasculare determinate de actiunea peroxizilor glicoproteinfixati
AU652988B2 (en) Method for insuring adequate intracellular glutathione in tissue
ATE73462T1 (de) Hirudin-variante, deren verwendung und herstellung.
IS6654A (is) Stöðugt gabapentín með pH innan stýrðra marka
ES2039578T3 (es) Procedimiento para producir mercapto-acilaminoacidos antihipertensivos.
ATE95818T1 (de) Protein-s-haeltige pharmazeutische praeparation.
DK43891A (da) Pentapeptid og fremgangsmaade til fremstilling deraf
TR200003552T2 (tr) İnsan proteini C polipeptit.
KR890701732A (ko) 개량형 조직 플라스미노겐 활성화 인자
ES2186782T3 (es) Uso de derivados de tropolona como inhibidores de la enzima inositol-monofosfatasa.
UA28481A (uk) Спосіб лікування гострого деструктивного панкреатиту
IT1248592B (it) Detossificazione delle acque di vegetazione
AU5199286A (en) New use of 1,4-dihydropyridine derivatives
FR2644061B1 (da)
AU99526S (en) Tap washer
AU110262S (en) Mitten
AU124219S (en) Edging
ES2060153T3 (es) Composicion terapeutica y cajita para el tratamiento de la poliartritis reumatoide.
AU107839S (en) A deck chair
AU143804S (en) Gaming machine
AU143805S (en) Gaming machine