DK0481253T3 - Nye p-oxybenzoesyrederivater, fremgangsmåde til deres fremstilling og deres anvendelse som lægemiddel - Google Patents

Nye p-oxybenzoesyrederivater, fremgangsmåde til deres fremstilling og deres anvendelse som lægemiddel

Info

Publication number
DK0481253T3
DK0481253T3 DK91116325.1T DK91116325T DK0481253T3 DK 0481253 T3 DK0481253 T3 DK 0481253T3 DK 91116325 T DK91116325 T DK 91116325T DK 0481253 T3 DK0481253 T3 DK 0481253T3
Authority
DK
Denmark
Prior art keywords
image
preparation
acid derivatives
drug
novel
Prior art date
Application number
DK91116325.1T
Other languages
English (en)
Inventor
Friedemann Dr Reiter
Peter Dr Jank
Michael Schliack
Kaisli Kaipainen-Reiter
Gerhard Lang
Anke Schink
Original Assignee
Klinge Co Chem Pharm Fab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Klinge Co Chem Pharm Fab filed Critical Klinge Co Chem Pharm Fab
Application granted granted Critical
Publication of DK0481253T3 publication Critical patent/DK0481253T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C63/00—Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
    • C07C63/04—Monocyclic monocarboxylic acids
    • C07C63/06—Benzoic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/21—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups
    • C07C65/24—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups polycyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
    • C07C69/84—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring
    • C07C69/92—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring with etherified hydroxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
    • C07D317/24—Radicals substituted by singly bound oxygen or sulfur atoms esterified

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK91116325.1T 1990-10-09 1991-09-25 Nye p-oxybenzoesyrederivater, fremgangsmåde til deres fremstilling og deres anvendelse som lægemiddel DK0481253T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4032037A DE4032037A1 (de) 1990-10-09 1990-10-09 Neue p-oxibenzoesaeurederivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel

Publications (1)

Publication Number Publication Date
DK0481253T3 true DK0481253T3 (da) 1995-05-22

Family

ID=6415946

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91116325.1T DK0481253T3 (da) 1990-10-09 1991-09-25 Nye p-oxybenzoesyrederivater, fremgangsmåde til deres fremstilling og deres anvendelse som lægemiddel

Country Status (15)

Country Link
US (1) US5153353A (da)
EP (1) EP0481253B1 (da)
JP (1) JPH0791221B2 (da)
KR (1) KR950004034B1 (da)
AT (1) ATE116281T1 (da)
AU (1) AU640810B2 (da)
CA (1) CA2048355C (da)
DE (2) DE4032037A1 (da)
DK (1) DK0481253T3 (da)
EE (1) EE02938B1 (da)
ES (1) ES2066309T3 (da)
GR (1) GR3015480T3 (da)
IE (1) IE65962B1 (da)
PT (1) PT98614B (da)
ZA (1) ZA918023B (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4314175C2 (de) * 1993-04-29 1995-03-30 Klinge Co Chem Pharm Fab Modifikation II von Lifibrol
DE4414537A1 (de) * 1994-04-26 1995-11-02 Klinge Co Chem Pharm Fab Kombinationspräparate mit einem Gehalt an einem p-Oxybenzoesäurederivat und einem HMG-CoA-Reduktase-Hemmer

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4109013A (en) * 1974-12-20 1978-08-22 Klinge Pharma Gmbh & Co. Substituted propanol-(2) derivatives of hydroxamic acids and the use thereof as hypolipemic drugs
DE2460689C3 (de) * 1974-12-20 1980-06-26 Klinge Pharma Gmbh & Co, 8000 Muenchen 13-disubstituierte Propanol-(2)-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
DE2735856A1 (de) * 1977-08-09 1979-02-22 Klinge Co Chem Pharm Fab Neue 1,3-diphenoxypropan-2-on-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE3326164A1 (de) * 1983-07-20 1985-01-31 Klinge Pharma GmbH, 8000 München Neue p-oxibenzoesaeure-derivate, sowie verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
EP0286703A1 (de) * 1987-04-14 1988-10-19 Klinge Pharma GmbH Neue Benzoesäure-Derivate, sowie Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel

Also Published As

Publication number Publication date
CA2048355A1 (en) 1992-04-10
ZA918023B (en) 1992-07-29
PT98614B (pt) 1999-01-29
EP0481253A3 (en) 1992-10-21
AU8241691A (en) 1992-06-11
AU640810B2 (en) 1993-09-02
US5153353A (en) 1992-10-06
JPH04273846A (ja) 1992-09-30
GR3015480T3 (en) 1995-06-30
CA2048355C (en) 1997-11-18
DE59104058D1 (de) 1995-02-09
KR950004034B1 (ko) 1995-04-22
KR920007977A (ko) 1992-05-27
PT98614A (pt) 1992-06-30
EP0481253B1 (de) 1994-12-28
IE913453A1 (en) 1992-04-22
ATE116281T1 (de) 1995-01-15
IE65962B1 (en) 1995-11-29
JPH0791221B2 (ja) 1995-10-04
ES2066309T3 (es) 1995-03-01
EE02938B1 (et) 1996-08-15
EP0481253A2 (de) 1992-04-22
DE4032037A1 (de) 1992-04-16

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