DK0481299T3 - N-phenyl-piperidyl-4-aminer og lægemidler indeholdende disse - Google Patents

N-phenyl-piperidyl-4-aminer og lægemidler indeholdende disse

Info

Publication number: DK0481299T3
Authority: DK; Denmark
Prior art keywords: phenyl; piperidyl; amines; drugs containing; alkyl
Prior art date: 1990-10-16

Application number

DK91116915.9T

Other languages

Danish (da)

English (en)

Inventor

Wilfried Dr Lubisch

Sabine Dr Schult

Rudolf Dr Binder

Manfred Dr Raschack

Roland Dr Reinhardt

Dietmar Dr Seemann

Original Assignee

Basf Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-10-16

Filing date

1991-10-04

Publication date

1994-09-12

1991-10-04 Application filed by Basf Ag filed Critical Basf Ag

1994-09-12 Application granted granted Critical

1994-09-12 Publication of DK0481299T3 publication Critical patent/DK0481299T3/da

Links

239000003814 drug Substances 0.000 title abstract 2
229940079593 drug Drugs 0.000 title abstract 2
125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 3
MZAGXDHQGXUDDX-JSRXJHBZSA-N (e,2z)-4-ethyl-2-hydroxyimino-5-nitrohex-3-enamide Chemical compound [O-][N+](=O)C(C)C(/CC)=C/C(=N/O)/C(N)=O MZAGXDHQGXUDDX-JSRXJHBZSA-N 0.000 abstract 1
239000004480 active ingredient Substances 0.000 abstract 1
KMJZFJMFHOPFPJ-UHFFFAOYSA-N n-phenylpiperidin-1-amine Chemical class C1CCCCN1NC1=CC=CC=C1 KMJZFJMFHOPFPJ-UHFFFAOYSA-N 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
125000000876 trifluoromethoxy group Chemical group FC(F)(F)O* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Life Sciences & Earth Sciences (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Hydrogenated Pyridines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

DK91116915.9T 1990-10-16 1991-10-04 N-phenyl-piperidyl-4-aminer og lægemidler indeholdende disse DK0481299T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE4032766A DE4032766A1 (de)	1990-10-16	1990-10-16	Phenylpiperidinoylamine und diese enthaltende arzneimittel

Publications (1)

Publication Number	Publication Date
DK0481299T3 true DK0481299T3 (da)	1994-09-12

Family

ID=6416364

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK91116915.9T DK0481299T3 (da)	1990-10-16	1991-10-04	N-phenyl-piperidyl-4-aminer og lægemidler indeholdende disse

Country Status (7)

Country	Link
US (1)	US5260318A (fr)
EP (1)	EP0481299B1 (fr)
JP (1)	JPH04282366A (fr)
AT (1)	ATE108775T1 (fr)
CA (1)	CA2052797A1 (fr)
DE (2)	DE4032766A1 (fr)
DK (1)	DK0481299T3 (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ATE130851T1 (de) *	1991-03-14	1995-12-15	Basf Ag	Substituierte n-phenylpiperidine und arzneimittel daraus.
US5656642A (en) *	1993-04-07	1997-08-12	Otsuka Pharmaceutical Co., Ltd.	Peripheral vasodilating agent containing piperidine derivative as active ingredient
DE69931316D1 (de)	1998-08-18	2006-06-22	Hoffmann La Roche	Verwendung von Aryl-Cyclohexylamine Derivaten zur Herstellung von NMDA-Rezeptorblockern
EP0982026B1 (fr) *	1998-08-18	2006-05-17	F. Hoffmann-La Roche Ag	Utilisation de dérivés d'aryl-cyclohexylamine dans la fabrication d'agents bloquants du récepteur NMDA
CA2315050C (fr) *	1998-10-16	2009-02-03	Suntory Limited	Derives d'acide aminophenoxyacetique comme neuroprotecteurs
WO2002022579A2 (fr)	2000-09-11	2002-03-21	Sepracor, Inc.	Heterocycles sulfonamides antipsychotiques et leurs methodes d'utilisation
MY142362A (en) *	2004-01-29	2010-11-30	Otsuka Pharma Co Ltd	Pharmaceutical composition for promoting angiogenesis
DE102004061017A1 (de) *	2004-12-18	2006-06-22	Sanofi-Aventis Deutschland Gmbh	Piperidinsulfonylharnstoffe und -thioharnstoffe, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
CN105829304B (zh) *	2013-12-20	2019-09-20	中国人民解放军军事医学科学院毒物药物研究所	N,n’取代哌啶胺类化合物、其制备方法及用途
KR101646833B1 (ko) *	2014-07-15	2016-08-08	주식회사 큐리언트	염증성 질환 치료용 화합물
CA2978482C (fr)	2015-03-04	2020-05-26	Camso Inc.	Ensemble chenille pour la traction d'un vehicule

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE749887C (de) *	1941-10-02	1944-12-20		Verfahren zur Darstellung von substituierten 4-Aminopiperidinen
GB1052302A (fr) *	1963-04-22
GB1077173A (en) *	1965-03-19	1967-07-26	American Cyanamid Co	Substituted alkylene piperidines and methods of preparation thereof
US4198411A (en) *	1976-08-12	1980-04-15	Janssen Pharmaceutica N.V.	N-aryl-N-(1-L-4-piperidinyl)-arylaceytamides
DE3373466D1 (de) *	1982-06-10	1987-10-15	Beecham Wuelfing Gmbh & Co Kg	Amine derivatives
GB8710494D0 (en) *	1987-05-02	1987-06-03	Pfizer Ltd	Antiarrhythmic agents
US4902800A (en) *	1988-08-17	1990-02-20	American Home Products Corporation	1-Substituted-4-pyrrolidinopiperidines as inhibitors of interleukin 1
US5008267A (en) *	1988-10-29	1991-04-16	Mitsui Toatsu Chemicals, Incorporated	Pyrimidinedione compounds, method of producing the same and antiarrythmic agents containing the same

1990
- 1990-10-16 DE DE4032766A patent/DE4032766A1/de not_active Withdrawn
1991
- 1991-09-16 US US07/760,159 patent/US5260318A/en not_active Expired - Fee Related
- 1991-10-04 CA CA002052797A patent/CA2052797A1/fr not_active Abandoned
- 1991-10-04 DE DE59102245T patent/DE59102245D1/de not_active Expired - Fee Related
- 1991-10-04 EP EP91116915A patent/EP0481299B1/fr not_active Expired - Lifetime
- 1991-10-04 DK DK91116915.9T patent/DK0481299T3/da active
- 1991-10-04 AT AT91116915T patent/ATE108775T1/de not_active IP Right Cessation
- 1991-10-15 JP JP3265706A patent/JPH04282366A/ja not_active Withdrawn

Also Published As

Publication number	Publication date
DE4032766A1 (de)	1992-04-30
DE59102245D1 (de)	1994-08-25
CA2052797A1 (fr)	1992-04-17
US5260318A (en)	1993-11-09
ATE108775T1 (de)	1994-08-15
EP0481299A2 (fr)	1992-04-22
EP0481299A3 (en)	1992-08-19
JPH04282366A (ja)	1992-10-07
EP0481299B1 (fr)	1994-07-20

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