DK0482081T3 - Antiviralt præparat - Google Patents

Antiviralt præparat

Info

Publication number
DK0482081T3
DK0482081T3 DK90911382.1T DK90911382T DK0482081T3 DK 0482081 T3 DK0482081 T3 DK 0482081T3 DK 90911382 T DK90911382 T DK 90911382T DK 0482081 T3 DK0482081 T3 DK 0482081T3
Authority
DK
Denmark
Prior art keywords
ethyluracil
diaminopurine
inosine
thymine
uracil
Prior art date
Application number
DK90911382.1T
Other languages
Danish (da)
English (en)
Inventor
Britta Wahren
Johan Harmenberg
Bo Berg
Original Assignee
Britta Wahren
Johan Harmenberg
Oeberg Bo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Britta Wahren, Johan Harmenberg, Oeberg Bo filed Critical Britta Wahren
Application granted granted Critical
Publication of DK0482081T3 publication Critical patent/DK0482081T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK90911382.1T 1989-07-19 1990-07-10 Antiviralt præparat DK0482081T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8902568A SE464168B (sv) 1989-07-19 1989-07-19 Antiviral komposition bestaaende av en 3'-fluoro-2',3'-dideoxynukleosidfoerening och en 2',3'-dideoxynukleosidfoerening (exempelvis azt)

Publications (1)

Publication Number Publication Date
DK0482081T3 true DK0482081T3 (da) 1996-05-28

Family

ID=20376569

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90911382.1T DK0482081T3 (da) 1989-07-19 1990-07-10 Antiviralt præparat

Country Status (11)

Country Link
US (1) US5571798A (fr)
EP (1) EP0482081B1 (fr)
JP (1) JP3149179B2 (fr)
AT (1) ATE132752T1 (fr)
AU (1) AU630220B2 (fr)
CA (1) CA2063417C (fr)
DE (1) DE69024804T2 (fr)
DK (1) DK0482081T3 (fr)
ES (1) ES2083458T3 (fr)
SE (1) SE464168B (fr)
WO (1) WO1991001137A1 (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0470355T3 (da) * 1990-08-06 1996-07-15 American Cyanamid Co Fremgangsmåde til fremstilling af deoxynucleosider
EP0555302A1 (fr) * 1990-10-30 1993-08-18 The Wellcome Foundation Limited Procede de traitement des maladies demyelinisantes
IL100502A (en) * 1991-01-03 1995-12-08 Iaf Biochem Int PHARMACEUTICAL PREPARATIONS CONTAINING CIS-4-AMINO-1-) 2-HYDROXIMETHIL-1,3-OXETYOLEN-5-IL (-
WO1992020344A1 (fr) 1991-05-16 1992-11-26 Glaxo Group Limited Combinaisons antivirales contenant des analogues de nucleosides
GB9110874D0 (en) * 1991-05-20 1991-07-10 Iaf Biochem Int Medicaments
GB9226927D0 (en) * 1992-12-24 1993-02-17 Iaf Biochem Int Dideoxy nucleoside analogues
US5760013A (en) * 1996-08-21 1998-06-02 National Science Council Thymidylate analogs and the use thereof
US5925514A (en) * 1996-12-10 1999-07-20 The Regents Of The University Of California Apparatus for testing for infection by a retrovirus
US5968731A (en) * 1996-12-10 1999-10-19 The Regents Of The University Of California Apparatus for automated testing of biological specimens
US5841975A (en) * 1996-12-10 1998-11-24 The Regents Of The University Of California Method and apparatus for globally-accessible automated testing
DE19832519A1 (de) * 1998-07-20 2000-01-27 Hartmut Oswald Arzneimittelzubereitungen zur topischen Behandlung mukokutaner Herpesinfektionen sowie der Keratitis herpetica des Auges
US7534605B2 (en) * 1999-06-08 2009-05-19 Yissum Research Development Company Of The Hebrew University Of Jerusalem CD44 polypeptides, polynucleotides encoding same, antibodies directed thereagainst and method of using same for diagnosing and treating inflammatory diseases
CN1302779C (zh) * 2002-06-27 2007-03-07 美迪维尔公司 含有阿巴卡韦和阿洛夫定的药物制剂及其用途
EP1610782A1 (fr) * 2003-03-27 2006-01-04 Boehringer Ingelheim International GmbH Combinaison antivirale d'une dipyridodiazepinone et compose antiretroviral
WO2004087169A1 (fr) * 2003-03-27 2004-10-14 Boehringer Ingelheim International Gmbh Combinaison antivirale de nevirapine et d'un autre compose antiretroviral
EP1610781A1 (fr) 2003-03-27 2006-01-04 Boehringer Ingelheim International GmbH Combinaison antivirale de tipranavir et d'un autre compose antiretroviral
EA200800932A1 (ru) * 2005-09-26 2008-10-30 Фармассет, Инк. Модифицированные 4`-нуклеозиды в качестве противовирусных агентов
GB0608876D0 (en) * 2006-05-05 2006-06-14 Medivir Ab Combination therapy

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4724232A (en) * 1985-03-16 1988-02-09 Burroughs Wellcome Co. Treatment of human viral infections
AU570853B2 (en) * 1985-08-26 1988-03-24 United States of America, as represented by the Secretary, U.S. Department of Commerce, The Inhibition of infectivity and cytopathic effect of htlv-111/ lav by purine bases
US4879277A (en) * 1985-08-26 1989-11-07 The United States Of America As Represented By The Department Of Health And Human Services Antiviral compositions and methods
US4681933A (en) * 1986-05-01 1987-07-21 University Of Georgia Research Foundation, Inc. 2',3'-dideoxy-5-substituted uridines and related compounds as antiviral agents
US4916122A (en) * 1987-01-28 1990-04-10 University Of Georgia Research Foundation, Inc. 3'-Azido-2',3'-dideoxyuridine anti-retroviral composition
SE8602981D0 (sv) * 1986-07-04 1986-07-04 Astra Laekemedel Ab Novel medicinal use
US4880782A (en) * 1986-11-21 1989-11-14 Max-Planck-Gesellschaft Zur Foederung Der Wissenschaften E.V. Method of treating viral infections in humans and compositions therefor
EP0286825A3 (fr) * 1987-03-18 1989-04-12 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Utilisation du 3'-fluro-3'-deoxythymidine pour fabriquer un médicament pour le traitement des infections virales
US4908440A (en) * 1987-11-12 1990-03-13 Bristol Myers Company 2',3'-dideoxy-2'-fluoroarabinopyrimidine nucleosides
US4904770A (en) * 1988-03-24 1990-02-27 Bristol-Myers Company Production of 2',3'-dideoxy-2',3'-didehydronucleosides
US5122517A (en) * 1988-06-10 1992-06-16 Regents Of The University Of Minnesota Antiviral combination comprising nucleoside analogs
US5059418A (en) * 1989-09-20 1991-10-22 The Administrators Of The Tulane Educational Fund Synergistic effect of human recombinant interferon-beta on halogenated pyrimidines
US5026687A (en) * 1990-01-03 1991-06-25 The United States Of America As Represented By The Department Of Health And Human Services Treatment of human retroviral infections with 2',3'-dideoxyinosine alone and in combination with other antiviral compounds
GB9104740D0 (en) * 1991-03-06 1991-04-17 Wellcome Found Antiviral nucleoside combination

Also Published As

Publication number Publication date
ES2083458T3 (es) 1996-04-16
DE69024804T2 (de) 1996-08-29
EP0482081A1 (fr) 1992-04-29
SE8902568D0 (sv) 1989-07-19
JPH04506961A (ja) 1992-12-03
US5571798A (en) 1996-11-05
AU630220B2 (en) 1992-10-22
DE69024804D1 (de) 1996-02-22
CA2063417C (fr) 2000-12-12
SE464168B (sv) 1991-03-18
JP3149179B2 (ja) 2001-03-26
ATE132752T1 (de) 1996-01-15
CA2063417A1 (fr) 1991-01-20
AU6046990A (en) 1991-02-22
WO1991001137A1 (fr) 1991-02-07
EP0482081B1 (fr) 1996-01-10
SE8902568L (sv) 1991-01-20

Similar Documents

Publication Publication Date Title
DK0482081T3 (da) Antiviralt præparat
FR2596761B1 (fr) Derives de nucleosides et leur utilisation pour la synthese d'oligonucleotides
FI932870A0 (fi) 2'-deoxi-2'2'-difluor-(4-substituerad pyrimidin)nukleosider med virus-och cancerhaemmande aktivitet, samt mellanprodukter
CA2053339A1 (fr) Hydroxymethyl(methylenecyclopentyl) purines et pyrimidines
HU9601774D0 (en) L-nucleosides for the treatment of hepatitis b-virus and epstein-bar virus
CA2268703A1 (fr) Nucleosides a base de .beta.-d dioxolane sous forme d'enantiomere pur, manifestant une activite selective contre le virus de l'hepatite b
EP0398231A3 (fr) Analogues nucléosides
MY102693A (en) Antiviral nucleosides
DK0805683T3 (da) 5-fluor-2',3'-umættet-pyrimidinnukleosider
IL84810A (en) Pharmaceutical antiviral compositions containing 1-beta-d-arabinofuranosyl-5-(1-alkynyl)cytosine and uracil derivatives thereof,some new such compounds and their preparation
FI920197A7 (fi) Viruksenvastaisia pyrimidiininukleosidejä
IE46107L (en) Pyrimidine nucleosides
ES8706163A1 (es) Procedimiento para la fabricacion de nuevos derivados nu- cleosidos
KR900007863A (ko) 향비루스제
FI932868A0 (fi) 2'-deoxi-2'2'-difluor(2,6,8-substituerade) purinnukleosider med virus-och cancerhaemmande aktivitet, samt mellanprodukter
DK630589D0 (da) 2',3'-dideoxypurinnucleosid/purinnucleosid-phosphorylase-inhibitor-sammensaetning
DE3854811D1 (de) Anti-HIV Pyrimidin Nucleoside
EP0034424A3 (fr) Composés contenant un noyau à sept chainons, comme inhibiteurs de cytidine déaminase
IL80004A0 (en) 7-aminoazolo(1,5-a)pyrimidines and their use as fungicides
NO891835D0 (no) Prodrug-former av 2',3'-didehydro-2',3'-dideoksy-nukleosider.
WO2001006986A3 (fr) Analogues uracile 5-(e)- bromovinyl et nucleosides pyrimidines associes ayant la fonction d'agents anti-viraux et procedes associes
KR960701639A (ko) 심기능 회복제(heart function restorative)
GB9506644D0 (en) Preparation of nucleoside analogues
EP0381533A3 (fr) Monophosphates cycliques d'acyclonucléosides de purine et de pyrimidine
JPS6426594A (en) Nucleotides and antitumor agent