DK0482844T3 - GL-7ACA-acylase - Google Patents
GL-7ACA-acylaseInfo
- Publication number
- DK0482844T3 DK0482844T3 DK91309666.5T DK91309666T DK0482844T3 DK 0482844 T3 DK0482844 T3 DK 0482844T3 DK 91309666 T DK91309666 T DK 91309666T DK 0482844 T3 DK0482844 T3 DK 0482844T3
- Authority
- DK
- Denmark
- Prior art keywords
- glu
- aca
- 7aca acylase
- gln
- 7aca
- Prior art date
Links
- 108010034416 glutarylamidocephalosporanic acid acylase Proteins 0.000 title abstract 3
- HSHGZXNAXBPPDL-HZGVNTEJSA-N 7beta-aminocephalosporanic acid Chemical compound S1CC(COC(=O)C)=C(C([O-])=O)N2C(=O)[C@@H]([NH3+])[C@@H]12 HSHGZXNAXBPPDL-HZGVNTEJSA-N 0.000 abstract 2
- IXUSDMGLUJZNFO-BXUZGUMPSA-N (7R)-7-(4-carboxybutanamido)cephalosporanic acid Chemical compound S1CC(COC(=O)C)=C(C(O)=O)N2C(=O)[C@@H](NC(=O)CCCC(O)=O)[C@@H]12 IXUSDMGLUJZNFO-BXUZGUMPSA-N 0.000 abstract 1
- 125000001429 N-terminal alpha-amino-acid group Chemical group 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 230000002255 enzymatic effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000002415 sodium dodecyl sulfate polyacrylamide gel electrophoresis Methods 0.000 abstract 1
- -1 succinyl 7-ACA Chemical compound 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
- C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
- C12P35/02—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin by desacylation of the substituent in the 7 position
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB909022907A GB9022907D0 (en) | 1990-10-22 | 1990-10-22 | Novel gl-7aca acylase |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0482844T3 true DK0482844T3 (da) | 1996-02-19 |
Family
ID=10684121
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK91309666.5T DK0482844T3 (da) | 1990-10-22 | 1991-10-18 | GL-7ACA-acylase |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US5310659A (da) |
| EP (1) | EP0482844B1 (da) |
| JP (1) | JP3030982B2 (da) |
| AT (1) | ATE133710T1 (da) |
| DE (1) | DE69116795T2 (da) |
| DK (1) | DK0482844T3 (da) |
| ES (1) | ES2085439T3 (da) |
| GB (1) | GB9022907D0 (da) |
| GR (1) | GR3018858T3 (da) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW400384B (en) * | 1993-11-01 | 2000-08-01 | Fujisawa Pharmaceutical Co | A new cephalosporin C acylase |
| US6465227B1 (en) * | 1997-09-09 | 2002-10-15 | Biochemie Gesellschaft M.B.H. | Spherical particles containing microorganism cells having enzyme activity |
| JP2004524006A (ja) | 2000-09-22 | 2004-08-12 | ブリストル−マイヤーズ スクイブ カンパニー | シュードモナス・ディミヌタｂｓ−２０３からのグルタリルセファロスポリンアミダーゼ |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA979832A (en) * | 1971-05-31 | 1975-12-16 | Kunio Matsumoto | Production of 7-amino desacetoxy cephalosporanic acid from bacillus |
| JPS60110292A (ja) * | 1983-11-22 | 1985-06-15 | Asahi Chem Ind Co Ltd | セフアロスポリン・アシラ−ゼ産生遺伝情報を担うｄνａ断片 |
| EP0465600B1 (en) * | 1989-04-04 | 1995-06-07 | Biopure Corporation | Enzymatic production of 7-amino cephalosporanic acid |
-
1990
- 1990-10-22 GB GB909022907A patent/GB9022907D0/en active Pending
-
1991
- 1991-10-18 ES ES91309666T patent/ES2085439T3/es not_active Expired - Lifetime
- 1991-10-18 US US07/779,049 patent/US5310659A/en not_active Expired - Fee Related
- 1991-10-18 DK DK91309666.5T patent/DK0482844T3/da active
- 1991-10-18 AT AT91309666T patent/ATE133710T1/de not_active IP Right Cessation
- 1991-10-18 EP EP91309666A patent/EP0482844B1/en not_active Expired - Lifetime
- 1991-10-18 DE DE69116795T patent/DE69116795T2/de not_active Expired - Fee Related
- 1991-10-22 JP JP3274035A patent/JP3030982B2/ja not_active Expired - Lifetime
-
1993
- 1993-06-22 US US08/080,240 patent/US5312750A/en not_active Expired - Fee Related
-
1996
- 1996-02-01 GR GR960400143T patent/GR3018858T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE69116795T2 (de) | 1996-05-30 |
| EP0482844A2 (en) | 1992-04-29 |
| GR3018858T3 (en) | 1996-05-31 |
| US5310659A (en) | 1994-05-10 |
| JPH0584077A (ja) | 1993-04-06 |
| ES2085439T3 (es) | 1996-06-01 |
| ATE133710T1 (de) | 1996-02-15 |
| DE69116795D1 (de) | 1996-03-14 |
| GB9022907D0 (en) | 1990-12-05 |
| EP0482844B1 (en) | 1996-01-31 |
| EP0482844A3 (en) | 1993-01-13 |
| US5312750A (en) | 1994-05-17 |
| JP3030982B2 (ja) | 2000-04-10 |
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