DK0482844T3 - GL-7ACA-acylase - Google Patents

GL-7ACA-acylase

Info

Publication number: DK0482844T3
Authority: DK; Denmark
Prior art keywords: glu; aca; 7aca acylase; gln; 7aca
Prior art date: 1990-10-22

Application number

DK91309666.5T

Other languages

English (en)

Inventor

Masao Fukagawa

Morita Iwami

Hitoshi Kojo

Ichiro Aramori

Hiroki Ono

Yosuke Ishitani

Mana Tsumura

Original Assignee

Fujisawa Pharmaceutical Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-10-22

Filing date

1991-10-18

Publication date

1996-02-19

1991-10-18 Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co

1996-02-19 Application granted granted Critical

1996-02-19 Publication of DK0482844T3 publication Critical patent/DK0482844T3/da

Links

108010034416 glutarylamidocephalosporanic acid acylase Proteins 0.000 title abstract 3
HSHGZXNAXBPPDL-HZGVNTEJSA-N 7beta-aminocephalosporanic acid Chemical compound S1CC(COC(=O)C)=C(C([O-])=O)N2C(=O)[C@@H]([NH3+])[C@@H]12 HSHGZXNAXBPPDL-HZGVNTEJSA-N 0.000 abstract 2
IXUSDMGLUJZNFO-BXUZGUMPSA-N (7R)-7-(4-carboxybutanamido)cephalosporanic acid Chemical compound S1CC(COC(=O)C)=C(C(O)=O)N2C(=O)[C@@H](NC(=O)CCCC(O)=O)[C@@H]12 IXUSDMGLUJZNFO-BXUZGUMPSA-N 0.000 abstract 1
125000001429 N-terminal alpha-amino-acid group Chemical group 0.000 abstract 1
238000006243 chemical reaction Methods 0.000 abstract 1
230000002255 enzymatic effect Effects 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
238000002415 sodium dodecyl sulfate polyacrylamide gel electrophoresis Methods 0.000 abstract 1
-1 succinyl 7-ACA Chemical compound 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
- C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
- C12P35/02—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin by desacylation of the substituent in the 7 position

Landscapes

Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Engineering & Computer Science (AREA)
Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Genetics & Genomics (AREA)
General Engineering & Computer Science (AREA)
Microbiology (AREA)
Biotechnology (AREA)
General Health & Medical Sciences (AREA)
Biochemistry (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Biomedical Technology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Enzymes And Modification Thereof (AREA)
Medicines Containing Plant Substances (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Saccharide Compounds (AREA)

DK91309666.5T 1990-10-22 1991-10-18 GL-7ACA-acylase DK0482844T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB909022907A GB9022907D0 (en)	1990-10-22	1990-10-22	Novel gl-7aca acylase

Publications (1)

Publication Number	Publication Date
DK0482844T3 true DK0482844T3 (da)	1996-02-19

Family

ID=10684121

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK91309666.5T DK0482844T3 (da)	1990-10-22	1991-10-18	GL-7ACA-acylase

Country Status (9)

Country	Link
US (2)	US5310659A (da)
EP (1)	EP0482844B1 (da)
JP (1)	JP3030982B2 (da)
AT (1)	ATE133710T1 (da)
DE (1)	DE69116795T2 (da)
DK (1)	DK0482844T3 (da)
ES (1)	ES2085439T3 (da)
GB (1)	GB9022907D0 (da)
GR (1)	GR3018858T3 (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
TW400384B (en) *	1993-11-01	2000-08-01	Fujisawa Pharmaceutical Co	A new cephalosporin C acylase
KR100481138B1 (ko) *	1997-09-09	2005-04-11	바이오케미 게젤샤프트 엠베하	효소 활성을 갖는 미생물을 함유하는 구형 입자 및 구형 입자의 제조방법
HUP0301202A2 (hu)	2000-09-22	2003-09-29	Bristol-Myers Squibb Company	Glutaril-cefalosporin amidáz Pseudomonas diminuta BS-203-ból

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA979832A (en) *	1971-05-31	1975-12-16	Kunio Matsumoto	Production of 7-amino desacetoxy cephalosporanic acid from bacillus
JPS60110292A (ja) *	1983-11-22	1985-06-15	Asahi Chem Ind Co Ltd	セフアロスポリン・アシラ−ゼ産生遺伝情報を担うｄνａ断片
EP0465600B1 (en) *	1989-04-04	1995-06-07	Biopure Corporation	Enzymatic production of 7-amino cephalosporanic acid

1990
- 1990-10-22 GB GB909022907A patent/GB9022907D0/en active Pending
1991
- 1991-10-18 US US07/779,049 patent/US5310659A/en not_active Expired - Fee Related
- 1991-10-18 DK DK91309666.5T patent/DK0482844T3/da active
- 1991-10-18 DE DE69116795T patent/DE69116795T2/de not_active Expired - Fee Related
- 1991-10-18 AT AT91309666T patent/ATE133710T1/de not_active IP Right Cessation
- 1991-10-18 EP EP91309666A patent/EP0482844B1/en not_active Expired - Lifetime
- 1991-10-18 ES ES91309666T patent/ES2085439T3/es not_active Expired - Lifetime
- 1991-10-22 JP JP3274035A patent/JP3030982B2/ja not_active Expired - Lifetime
1993
- 1993-06-22 US US08/080,240 patent/US5312750A/en not_active Expired - Fee Related
1996
- 1996-02-01 GR GR960400143T patent/GR3018858T3/el unknown

Also Published As

Publication number	Publication date
EP0482844A3 (en)	1993-01-13
GB9022907D0 (en)	1990-12-05
EP0482844A2 (en)	1992-04-29
DE69116795T2 (de)	1996-05-30
JPH0584077A (ja)	1993-04-06
ES2085439T3 (es)	1996-06-01
ATE133710T1 (de)	1996-02-15
DE69116795D1 (de)	1996-03-14
JP3030982B2 (ja)	2000-04-10
EP0482844B1 (en)	1996-01-31
US5312750A (en)	1994-05-17
GR3018858T3 (en)	1996-05-31
US5310659A (en)	1994-05-10

Publication	Publication Date	Title
DE69117843D1 (de)	1996-04-18	Cephalosporin C Acylase
DE69428165D1 (de)	2001-10-11	Teilhydrolysat aus Milcheiweiss und Verfahren zu dessen Herstellung
DE69116305D1 (de)	1996-02-22	Verfahren zur Herstellung von Trehalulose und Isomaltulose
NO933525D0 (no)	1993-10-01	Xylanase, tilsvarende rekombinant dna-sekvens, xylanaseholding middel og anvendelse av middelet
ES2077151T3 (es)	1995-11-16	Penicilina g-acilasa, gen codificador de la misma y procedimiento de produccion de esta enzima.
DE68915692D1 (de)	1994-07-07	Fermentationsverfahren zur Herstellung von 2-Keto-L-Gulonsäure.
ES8702946A1 (es)	1987-01-16	Procedimiento para preparar d-aminoacido-transaminasa
ATE133710T1 (de)	1996-02-15	Gl-7aca acylase
ES2018734A6 (es)	1991-05-01	Procedimiento para la obtencion de un enzima proteolitico.
EP0289804A3 (en)	1990-06-13	Process for preparing optically active mercapto compound
DK392087A (da)	1988-01-30	Antibiotikum a 42867 og syreadditionssalte deraf
DE3460566D1 (en)	1986-10-02	Process for the preparation of the optic antipodes of tertiary leucine
IL101172A0 (en)	1992-11-15	Process for the preparation of ma
JPS6474986A (en)	1989-03-20	Protease and a novel microorganism producing the same
SU1356455A1 (ru)	1996-03-27	Способ получения основы питательной среды для приготовления стафилококкового энтеротоксина типа а