DK0508842T3 - Acylaminophenolderivater, fremgangsmåde til fremstilling heraf samt farmaceutiske midler indeholdende disse - Google Patents

Acylaminophenolderivater, fremgangsmåde til fremstilling heraf samt farmaceutiske midler indeholdende disse

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Publication number
DK0508842T3
DK0508842T3 DK92400576.2T DK92400576T DK0508842T3 DK 0508842 T3 DK0508842 T3 DK 0508842T3 DK 92400576 T DK92400576 T DK 92400576T DK 0508842 T3 DK0508842 T3 DK 0508842T3
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DK
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alkyl
represent
different
processes
preparation
Prior art date
Application number
DK92400576.2T
Other languages
English (en)
Inventor
Charles Malen
Jean-Michel Lacoste
Jean-Paul Vilaine
Albert Lenaers
Original Assignee
Adir
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Publication of DK0508842T3 publication Critical patent/DK0508842T3/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • C07C233/24—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
    • C07C233/26—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to an acyclic carbon atom of a saturated carbon skeleton containing rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • C07C233/24—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
    • C07C233/25—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • C07C233/24—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
    • C07C233/27—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a carbon atom of an acyclic unsaturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK92400576.2T 1991-03-08 1992-03-06 Acylaminophenolderivater, fremgangsmåde til fremstilling heraf samt farmaceutiske midler indeholdende disse DK0508842T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9102800A FR2673625B1 (fr) 1991-03-08 1991-03-08 Nouveaux derives d'acylaminophenol, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.

Publications (1)

Publication Number Publication Date
DK0508842T3 true DK0508842T3 (da) 1995-01-02

Family

ID=9410501

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92400576.2T DK0508842T3 (da) 1991-03-08 1992-03-06 Acylaminophenolderivater, fremgangsmåde til fremstilling heraf samt farmaceutiske midler indeholdende disse

Country Status (13)

Country Link
US (1) US5254590A (da)
EP (1) EP0508842B1 (da)
JP (1) JPH07587B2 (da)
AT (1) ATE109766T1 (da)
AU (1) AU643368B2 (da)
CA (1) CA2062437A1 (da)
DE (1) DE69200311T2 (da)
DK (1) DK0508842T3 (da)
ES (1) ES2062870T3 (da)
FR (1) FR2673625B1 (da)
IE (1) IE65579B1 (da)
NZ (1) NZ241864A (da)
ZA (1) ZA921703B (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3720395B2 (ja) 1994-09-20 2005-11-24 京都薬品工業株式会社 新規ヘテロ環誘導体、その製造方法およびその医薬用途
EP0726247B1 (en) * 1995-02-08 1998-07-08 Nippon Shoji Kaisha, Limited Aniline derivatives having a polyunsaturated fatty acid residue and use thereof
ATE210116T1 (de) 1995-10-05 2001-12-15 Kyoto Pharma Ind Neue heterozyklische derivate und ihre medizinische anwendung
FR2741619B1 (fr) * 1995-11-28 1998-02-13 Pf Medicament Nouveaux derives de 2,3,5-trimethyl-4-hydroxy-anilides, leur preparation et leur application en therapeutique
AU3458697A (en) * 1996-07-12 1998-02-09 Yamanouchi Pharmaceutical Co., Ltd. Propionanilide derivatives or salts thereof
IT1309421B1 (it) 1998-09-16 2002-01-23 Med Dia S R L Impiego della batocuproina (acido disolfonico) per la valutazione delpotere antiossidante (pao) nei liquidi e soluzioni.
RU2318808C2 (ru) 2002-07-17 2008-03-10 Киото Фармасьютикал Индастриз, Лтд. Новое соединение индолина и его применение в медицине
US7566808B2 (en) 2004-02-17 2009-07-28 President And Fellows Of Harvard College Management of ophthalmologic disorders, including macular degeneration
US20050288379A1 (en) * 2004-06-21 2005-12-29 Xiaoqiang Yan Benzoquinone compounds as anti-cancer agents
JP2008503579A (ja) * 2004-06-21 2008-02-07 ハッチソン メディファーマ エンタープライジズ リミテッド 癌の化学療法
WO2007127908A2 (en) * 2006-04-28 2007-11-08 Hutchison Medipharma Enterprises Limited Dihydrobenzoquinone compounds
FR2973374B1 (fr) * 2011-04-04 2013-08-23 Pf Medicament Nouveaux alkylthioethers, leur preparation et leur application en therapeutique
WO2014080306A2 (en) * 2012-11-20 2014-05-30 Mahesh Kandula Compositions and methods for the treatment of cardiovascular diseases
NZ718411A (en) 2014-08-26 2018-09-28 Kando Innovation Ltd Productivity enhancement for band saw

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2852540A (en) * 1954-08-09 1958-09-16 Exxon Research Engineering Co Oil soluble alkali and alkaline earth metal salts of p-acylamino phenols
US3621043A (en) * 1963-02-06 1971-11-16 Sumitomo Chemical Co N-substituted octadecadienoic acid amides as cholesterol lowering agents
NL130295C (da) * 1964-04-28
US3479377A (en) * 1965-12-20 1969-11-18 Ashland Oil Inc Hydroxy phenyl fatty amides and polymers thereof,their preparation and use
NL150334B (nl) * 1966-10-04 1976-08-16 Sumito Chemical Werkwijze voor het bereiden van een geneesmiddel met cholesterolspiegel-verlagende werking, alsmede gevormd geneesmiddel.
US3784577A (en) * 1971-10-26 1974-01-08 Sumitomo Chemical Co Fatty acid amide derivatives
US4751026A (en) * 1986-03-24 1988-06-14 Warner-Lambert Company Substituted anilides of oleic, linoleic, or linolenic acid as inhibitors of acyl-coa:cholesterol acyltransferase
US4716175A (en) * 1987-02-24 1987-12-29 Warner-Lambert Company Saturated fatty acid amides as inhibitors of acyl-CoA:cholesterol acyltransferase
AU7745991A (en) * 1990-04-11 1991-10-30 Warner-Lambert Company Amide ester acat inhibitors
JPH0454119A (ja) * 1990-06-20 1992-02-21 Tanabe Seiyaku Co Ltd ５―リポキシゲナーゼ阻害剤

Also Published As

Publication number Publication date
IE65579B1 (en) 1995-11-01
EP0508842B1 (fr) 1994-08-10
CA2062437A1 (fr) 1992-09-09
US5254590A (en) 1993-10-19
ATE109766T1 (de) 1994-08-15
JPH07587B2 (ja) 1995-01-11
NZ241864A (en) 1993-10-26
ZA921703B (en) 1992-11-25
DE69200311D1 (de) 1994-09-15
JPH04327564A (ja) 1992-11-17
FR2673625A1 (fr) 1992-09-11
AU643368B2 (en) 1993-11-11
AU1146992A (en) 1992-09-10
EP0508842A1 (fr) 1992-10-14
IE920719A1 (en) 1992-09-09
DE69200311T2 (de) 1995-03-30
FR2673625B1 (fr) 1993-05-07
ES2062870T3 (es) 1994-12-16

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