DK0552373T3 - Apoptoseregulator - Google Patents

Apoptoseregulator

Info

Publication number
DK0552373T3
DK0552373T3 DK92914177T DK92914177T DK0552373T3 DK 0552373 T3 DK0552373 T3 DK 0552373T3 DK 92914177 T DK92914177 T DK 92914177T DK 92914177 T DK92914177 T DK 92914177T DK 0552373 T3 DK0552373 T3 DK 0552373T3
Authority
DK
Denmark
Prior art keywords
apoptosis regulator
apoptosis
regulator
Prior art date
Application number
DK92914177T
Other languages
English (en)
Inventor
Satoru Nakai
Masakazu Adachi
Koutoku Aihara
Hitomi Mori
Michiaki Tominaga
Hiroyuki Ichikawa
Seiji Akamatsu
Fumio Saito
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Application granted granted Critical
Publication of DK0552373T3 publication Critical patent/DK0552373T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK92914177T 1991-07-03 1992-07-02 Apoptoseregulator DK0552373T3 (da)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP16258791 1991-07-03
JP3346992 1992-02-20
JP4571892 1992-03-03
JP10058592 1992-03-25
PCT/JP1992/000841 WO1993000902A1 (fr) 1991-07-03 1992-07-02 Regulateur d'apoptose

Publications (1)

Publication Number Publication Date
DK0552373T3 true DK0552373T3 (da) 1999-12-27

Family

ID=27459795

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92914177T DK0552373T3 (da) 1991-07-03 1992-07-02 Apoptoseregulator

Country Status (11)

Country Link
US (5) US5672603A (da)
EP (1) EP0552373B1 (da)
KR (1) KR100196368B1 (da)
AU (1) AU648690B2 (da)
CA (1) CA2090876A1 (da)
DE (1) DE69230131T2 (da)
DK (1) DK0552373T3 (da)
ES (1) ES2138971T3 (da)
MX (1) MX9203950A (da)
TW (1) TW229157B (da)
WO (1) WO1993000902A1 (da)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5464833A (en) * 1992-08-19 1995-11-07 Otsuka Pharmaceutical Co., Ltd. Apoptosis regulating composition
CA2134880A1 (en) * 1993-03-02 1994-09-03 Otsuka Pharmaceutical Co., Ltd. Graft rejection inhibitor and il-1 production inhibitor
GB9311132D0 (en) 1993-05-28 1993-07-14 Eisai London Res Lab Ltd Control of cell death
CA2150546C (en) * 1993-10-21 2004-11-09 Takahide Matsuda Agent for inhibiting production of interleukin-8
US5504093A (en) * 1994-08-01 1996-04-02 Otsuka Pharmaceutical Co., Ltd. Method for inhibiting nucleoside and nucleobase transport in mammalian cells, and method for inhibition of DNA virus replication
EP0749311A1 (en) * 1995-01-11 1996-12-27 Otsuka Pharmaceutical Co., Ltd. Pharmaceutical composition of indene derivatives for regulating apoptosis
WO1998046229A1 (en) * 1995-06-21 1998-10-22 Otsuka Pharmaceutical Co., Ltd. Il-8 and mcaf production inhibitors
JPH0971532A (ja) * 1995-09-06 1997-03-18 Otsuka Pharmaceut Co Ltd 発癌抑制剤
US5700803A (en) * 1995-12-12 1997-12-23 Otsuka Pharmaceutical Co., Ltd. Method for reducing infarct size in subjects afflicted with ischemic heart disease
AU6854398A (en) * 1997-04-25 1998-11-24 Otsuka Pharmaceutical Co., Ltd. Hyaluronate synthesis inhibitors
US6008209A (en) * 1997-04-28 1999-12-28 Hoffmann-La Roche Inc. Method of using vitamin D3 analogs with bis C-20 side chains
US6544972B1 (en) 1997-09-25 2003-04-08 Regents Of The University Of Minnesota Methods of limiting apoptosis of cells
US6281191B1 (en) 1997-12-29 2001-08-28 Vladimir I. Slesarev Compositions and methods for treating hepatitis-C
FR2774289B1 (fr) * 1998-02-03 2002-05-24 Goemar Lab Sa Medicament pour le traitement des dereglements de l'apoptose
AU771224B2 (en) 1998-07-13 2004-03-18 Board Of Regents, The University Of Texas System Cancer treatment methods using antibodies to aminophospholipids
SI1107795T1 (en) 1998-09-04 2003-06-30 The Regents Of The University Of Michigan Thiomolybdate associated with at least one carbohydrate, and its use for preventing or treating diseases characterized by aberrant vascularization, such as cancer, wet type macular degeneration, rheumatoid arthritis
US6277974B1 (en) 1999-12-14 2001-08-21 Cogent Neuroscience, Inc. Compositions and methods for diagnosing and treating conditions, disorders, or diseases involving cell death
US20030044413A1 (en) * 2000-08-15 2003-03-06 Regents Of The University Of Minnesota Methods of limiting apoptosis of cells
US20050107451A1 (en) * 2001-12-20 2005-05-19 Portbury Stuart D. Methods for treating conditions, disorders, or diseases involving cell death
US7572442B2 (en) 2002-07-15 2009-08-11 Board Of Regents, The University Of Texas System Selected antibody compositions for binding to aminophospholipids
WO2004043342A2 (en) * 2002-11-07 2004-05-27 Regents Of The University Of Minnesota Methods of treating injuries of the nervous system associated with hemorrhage
US8431396B2 (en) 2003-03-21 2013-04-30 The Cleveland Clinic Foundation Anti-angiogenic peptides
US20060204481A1 (en) * 2003-04-02 2006-09-14 Steer Clifford J Methods of promoting cell viability
ES2410587T3 (es) 2004-01-22 2013-07-02 University Of Miami Formulaciones tópicas de coenzima Q10 y métodos de uso
US20080194531A1 (en) * 2005-02-10 2008-08-14 Steer Clifford J Methods for Treating Visual Disorders
MX2010005104A (es) 2007-11-09 2010-08-04 Peregrine Pharmaceuticals Inc Composiciones de anticuerpo anti-factor de crecimiento endotelial vascular y metodos.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5430184A (en) * 1977-08-10 1979-03-06 Otsuka Pharmaceut Co Ltd 3,4-dihydrocarbostyril derivative
JPS6038384B2 (ja) * 1978-03-24 1985-08-31 大塚製薬株式会社 チオセミカルバゾン誘導体
JPS5777676A (en) * 1980-10-31 1982-05-15 Otsuka Pharmaceut Co Ltd Carbostyril derivative
JPS5793962A (en) * 1980-12-01 1982-06-11 Otsuka Pharmaceut Co Ltd Carbostyryl derivative
JPS62135423A (ja) * 1985-12-09 1987-06-18 Otsuka Pharmaceut Co Ltd 低酸素症改善剤

Also Published As

Publication number Publication date
ES2138971T3 (es) 2000-02-01
EP0552373A4 (en) 1993-09-22
HK1004469A1 (en) 1998-11-27
KR930702002A (ko) 1993-09-08
AU2231792A (en) 1993-02-11
EP0552373A1 (en) 1993-07-28
TW229157B (da) 1994-09-01
US5925640A (en) 1999-07-20
CA2090876A1 (en) 1993-01-04
US5672603A (en) 1997-09-30
AU648690B2 (en) 1994-04-28
MX9203950A (es) 1993-05-01
KR100196368B1 (ko) 1999-06-15
WO1993000902A1 (fr) 1993-01-21
DE69230131D1 (de) 1999-11-18
DE69230131T2 (de) 2000-03-02
US5916890A (en) 1999-06-29
US5872120A (en) 1999-02-16
EP0552373B1 (en) 1999-10-13
US5798358A (en) 1998-08-25

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