DK0576439T3 - Monoklonalt antistof mod LPS-kerne - Google Patents

Monoklonalt antistof mod LPS-kerne

Info

Publication number
DK0576439T3
DK0576439T3 DK92904901T DK92904901T DK0576439T3 DK 0576439 T3 DK0576439 T3 DK 0576439T3 DK 92904901 T DK92904901 T DK 92904901T DK 92904901 T DK92904901 T DK 92904901T DK 0576439 T3 DK0576439 T3 DK 0576439T3
Authority
DK
Denmark
Prior art keywords
thr
leu
tyr
arg
ser
Prior art date
Application number
DK92904901T
Other languages
English (en)
Inventor
Hermann Gram
Padova Franco Di
George Robin Barclay
Ian Raymond Poxton
Original Assignee
Common Services Agency
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Common Services Agency filed Critical Common Services Agency
Application granted granted Critical
Publication of DK0576439T3 publication Critical patent/DK0576439T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203—Gram-negative bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
    • G01N2400/10—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • G01N2400/50—Lipopolysaccharides; LPS

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK92904901T 1991-03-13 1992-02-22 Monoklonalt antistof mod LPS-kerne DK0576439T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB919105292A GB9105292D0 (en) 1991-03-13 1991-03-13 Improvements in or relating to organic compounds
PCT/EP1992/000380 WO1992016624A1 (en) 1991-03-13 1992-02-22 Monoclonal antibody against lps core

Publications (1)

Publication Number Publication Date
DK0576439T3 true DK0576439T3 (da) 1999-11-01

Family

ID=10691487

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92904901T DK0576439T3 (da) 1991-03-13 1992-02-22 Monoklonalt antistof mod LPS-kerne

Country Status (10)

Country Link
EP (1) EP0576439B1 (da)
JP (1) JP3328277B2 (da)
AT (1) ATE179753T1 (da)
AU (1) AU1261192A (da)
CA (1) CA2105979C (da)
DE (1) DE69229110T2 (da)
DK (1) DK0576439T3 (da)
ES (1) ES2131526T3 (da)
GB (1) GB9105292D0 (da)
WO (1) WO1992016624A1 (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3484773D1 (de) * 1983-05-06 1991-08-08 Velos Group Mit endotoxinkern reaktionsfaehige monoklonale antikoerper.
DE69321218T2 (de) * 1992-02-19 1999-02-18 Schering Corp., Kenilworth, N.J. Klonierung und expression von humanisierten monoklonalen antikörpern gegen menschliches interleukin-4
US6749831B1 (en) 1997-05-16 2004-06-15 Medical Defense Technology, Llc Vaccine against lipopolysaccharide core
CA2491669A1 (en) 2002-07-04 2004-01-15 Oncomab Gmbh Neoplasm specific antibodies and uses thereof
DE10311248A1 (de) 2003-03-14 2004-09-30 Müller-Hermelink, Hans Konrad, Prof. Dr. Humaner monoklonaler Antikörper
DE10353175A1 (de) 2003-11-14 2005-06-16 Müller-Hermelink, Hans Konrad, Prof. Dr. Humaner monoklonaler Antikörper mit fettsenkender Wirkung
EP1531162A1 (en) 2003-11-14 2005-05-18 Heinz Vollmers Adenocarcinoma specific antibody SAM-6, and uses thereof
EP3461840A1 (en) 2009-04-27 2019-04-03 Immuron Limited Anti-lps enriched immunoglobulin preparation for use in treatment and/or prophylaxis of non alcoholic steatohepatitis
EP2605791B1 (en) 2010-08-17 2017-03-08 Immuron Limited Anti-lps enriched immunoglobulin preparation for use in treatment and/or prophylaxis of a pathologic disorder
DE102011006809A1 (de) 2011-04-05 2012-10-11 Freistaat Bayern vertreten durch die Julius-Maximilians-Universität Würzburg Verwendung eines Mittels aus Antikörpern und/oder Insulin-like growth factor-Antagonisten
DE102011006781A1 (de) * 2011-04-05 2012-10-11 Mat-Malta Advanced Technologies Limited Antikörperprodukt, umfassend n spezifische Antikörper
US11168131B2 (en) 2015-11-10 2021-11-09 Visterra, Inc. Antibody molecule-drug conjugates and uses thereof
ES2994374T3 (en) 2017-01-18 2025-01-23 Visterra Inc Antibody molecule-drug conjugates and uses thereof
EP4126064A1 (en) 2020-04-03 2023-02-08 Visterra, Inc. Antibody molecule-drug conjugates and uses thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3484773D1 (de) * 1983-05-06 1991-08-08 Velos Group Mit endotoxinkern reaktionsfaehige monoklonale antikoerper.
JPS61130300A (ja) * 1984-11-27 1986-06-18 ザ　ボ−ド　オブ　トラステイ−ズ　オブ　ザ　レランド　スタンフオ−ド　ジユニア　ユニバ−シテイ ヒトモノクロ−ナル抗体
GB8607679D0 (en) * 1986-03-27 1986-04-30 Winter G P Recombinant dna product
FR2606421B1 (fr) * 1986-11-12 1990-01-26 Roussel Uclaf Anticorps monoclonaux antigram (-) procede de preparation et applications
GB2218703B (en) * 1988-05-10 1992-10-28 Sumitomo Chemical Co Human monoclonal antibody to p.aeruginosa: its production and use
EP0434685A1 (en) * 1988-09-19 1991-07-03 Cetus Oncology Corporation Gram-negative bacterial endotoxin blocking monoclonal antibodies

Also Published As

Publication number Publication date
ATE179753T1 (de) 1999-05-15
DE69229110D1 (de) 1999-06-10
AU1261192A (en) 1992-10-21
CA2105979C (en) 2003-05-13
WO1992016624A1 (en) 1992-10-01
CA2105979A1 (en) 1992-09-14
DE69229110T2 (de) 1999-11-25
JPH06505867A (ja) 1994-07-07
JP3328277B2 (ja) 2002-09-24
ES2131526T3 (es) 1999-08-01
EP0576439B1 (en) 1999-05-06
GB9105292D0 (en) 1991-04-24
EP0576439A1 (en) 1994-01-05

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