DK0592600T3 - Protein S polypeptider og anvendelse deraf - Google Patents

Protein S polypeptider og anvendelse deraf

Info

Publication number
DK0592600T3
DK0592600T3 DK92915841T DK92915841T DK0592600T3 DK 0592600 T3 DK0592600 T3 DK 0592600T3 DK 92915841 T DK92915841 T DK 92915841T DK 92915841 T DK92915841 T DK 92915841T DK 0592600 T3 DK0592600 T3 DK 0592600T3
Authority
DK
Denmark
Prior art keywords
polypeptides
protein
useful
antibodies
c4bp
Prior art date
Application number
DK92915841T
Other languages
Danish (da)
English (en)
Inventor
John H Griffin
Jose A Fernandez
Original Assignee
Scripps Research Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/907,190 external-priority patent/US5321123A/en
Application filed by Scripps Research Inst filed Critical Scripps Research Inst
Application granted granted Critical
Publication of DK0592600T3 publication Critical patent/DK0592600T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745Blood coagulation or fibrinolysis factors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK92915841T 1991-07-02 1992-07-02 Protein S polypeptider og anvendelse deraf DK0592600T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US72474691A 1991-07-02 1991-07-02
US07/907,190 US5321123A (en) 1991-07-02 1992-07-01 Protein S polypeptides and anti-peptide antibodies that inhibit protein S binding to C4B binding protein, diagnostic systems and therapeutic methods
PCT/US1992/005599 WO1993001209A1 (fr) 1991-07-02 1992-07-02 Polypeptides de proteines s et leurs utilisations

Publications (1)

Publication Number Publication Date
DK0592600T3 true DK0592600T3 (da) 2000-04-17

Family

ID=27111033

Family Applications (2)

Application Number Title Priority Date Filing Date
DK92915841T DK0592600T3 (da) 1991-07-02 1992-07-02 Protein S polypeptider og anvendelse deraf
DK99202141T DK0972781T3 (da) 1991-07-02 1992-07-02 Protein S-polypeptider og anvendelser deraf

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK99202141T DK0972781T3 (da) 1991-07-02 1992-07-02 Protein S-polypeptider og anvendelser deraf

Country Status (10)

Country Link
EP (2) EP0524737A3 (fr)
AT (2) ATE350398T1 (fr)
AU (1) AU674496B2 (fr)
CA (1) CA2112701C (fr)
DE (2) DE69230614T2 (fr)
DK (2) DK0592600T3 (fr)
ES (2) ES2279598T3 (fr)
GR (1) GR3033242T3 (fr)
PT (1) PT592600E (fr)
WO (1) WO1993001209A1 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5863896A (en) * 1995-11-09 1999-01-26 Immuno Ag Evaluation of substances for altering and for increasing APC response
US6379975B1 (en) 1996-11-27 2002-04-30 T.A.C. Thrombosis And Coagulation Aktiebolag Methods and reagents for determining protein S
SE9604378D0 (sv) * 1996-11-27 1996-11-27 Tac Ab Methods and reagents for determining protein S
WO2004092735A2 (fr) * 2003-04-18 2004-10-28 Novartis Ag Methodes et compositions ciblant les tyrosine kinases pour le diagnostic et le traitement de l'osteoarthrite
FR2863616A1 (fr) * 2003-12-12 2005-06-17 Stago Diagnostica Dosage de la proteine s libre non clivee par le facteur xa et utilisation de ce dosage pour l'evaluation du potentiel de coagulation
EP1919499A2 (fr) * 2005-07-29 2008-05-14 Universiteit van Maastricht Regulation de l'activite du facteur tissulaire par la proteine s et inhibiteur de la voie du facteur tissulaire
JP2023524807A (ja) * 2020-05-05 2023-06-13 ベガ・セラピューティクス・インコーポレイテッド プロテインs抗体、その作製方法および使用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0271810B1 (fr) * 1986-12-15 1994-03-09 Teijin Limited Détermination immunologique de la protéine S humaine libre et du complexe de la protéine S-c4bp
EP0315447A3 (fr) * 1987-11-06 1990-07-18 Teijin Limited Procédé pour la mesure immunologique de protéine S et réactif et trousse utilisés à cet effet
JPH01231893A (ja) * 1988-03-14 1989-09-18 Fuji Yakuhin Kogyo Kk 抗ヒトプロテインsモノクローナル抗体およびその利用

Also Published As

Publication number Publication date
WO1993001209A1 (fr) 1993-01-21
DE69230614D1 (de) 2000-03-02
CA2112701C (fr) 2007-09-25
ATE350398T1 (de) 2007-01-15
DK0972781T3 (da) 2007-03-05
EP0524737A2 (fr) 1993-01-27
ES2142317T3 (es) 2000-04-16
AU674496B2 (en) 1997-01-02
EP0524737A3 (en) 1994-10-05
DE69230614T2 (de) 2000-06-21
ATE189232T1 (de) 2000-02-15
CA2112701A1 (fr) 1993-01-21
GR3033242T3 (en) 2000-09-29
EP0592600A1 (fr) 1994-04-20
ES2279598T3 (es) 2007-08-16
EP0592600A4 (fr) 1994-10-12
DE69233673T2 (de) 2007-10-04
EP0592600B1 (fr) 2000-01-26
PT592600E (pt) 2000-05-31
DE69233673D1 (de) 2007-02-15
AU2323092A (en) 1993-02-11

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