DK0593897T3 - Stabiliserede hexadecylphosphocholinopløsninger i glycerolalkylethere - Google Patents

Stabiliserede hexadecylphosphocholinopløsninger i glycerolalkylethere

Info

Publication number: DK0593897T3
Authority: DK; Denmark
Prior art keywords: solutions; alkyl ethers; hexadecylphosphocholine; stabilized; glycerol alkyl
Prior art date: 1992-10-23

Application number

DK93114672.4T

Other languages

Danish (da)

English (en)

Inventor

Juergen Prof Dr Engel

Elisabeth Dr Wolf-Heuss

Helmut Dr Orth

Burkhard Dr Wichert

Diester Sauerbier

Original Assignee

Asta Medica Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-10-23

Filing date

1993-09-13

Publication date

1996-05-13

1993-09-13 Application filed by Asta Medica Ag filed Critical Asta Medica Ag

1996-05-13 Application granted granted Critical

1996-05-13 Publication of DK0593897T3 publication Critical patent/DK0593897T3/da

Links

PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerol Natural products OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 title abstract 4
-1 glycerol alkyl ethers Chemical class 0.000 title abstract 2
PQLXHQMOHUQAKB-UHFFFAOYSA-N miltefosine Chemical compound CCCCCCCCCCCCCCCCOP([O-])(=O)OCC[N+](C)(C)C PQLXHQMOHUQAKB-UHFFFAOYSA-N 0.000 title 1
229960003775 miltefosine Drugs 0.000 title 1
239000003112 inhibitor Substances 0.000 abstract 1
230000003647 oxidation Effects 0.000 abstract 1
238000007254 oxidation reaction Methods 0.000 abstract 1
239000003755 preservative agent Substances 0.000 abstract 1
230000002335 preservative effect Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
- A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Oil, Petroleum & Natural Gas (AREA)
Inorganic Chemistry (AREA)
Dermatology (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Luminescent Compositions (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)

DK93114672.4T 1992-10-23 1993-09-13 Stabiliserede hexadecylphosphocholinopløsninger i glycerolalkylethere DK0593897T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE4235911A DE4235911A1 (de)	1992-10-23	1992-10-23	Stabilisierte Hexadecylphosphocholinlösungen in Glycerinalkylethern

Publications (1)

Publication Number	Publication Date
DK0593897T3 true DK0593897T3 (da)	1996-05-13

Family

ID=6471239

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK93114672.4T DK0593897T3 (da)	1992-10-23	1993-09-13	Stabiliserede hexadecylphosphocholinopløsninger i glycerolalkylethere

Country Status (14)

Country	Link
US (1)	US5446033A (fr)
EP (1)	EP0593897B1 (fr)
JP (1)	JPH06227987A (fr)
CN (1)	CN1052878C (fr)
AT (1)	ATE136784T1 (fr)
CA (1)	CA2109053C (fr)
DE (2)	DE4235911A1 (fr)
DK (1)	DK0593897T3 (fr)
EG (1)	EG20234A (fr)
ES (1)	ES2086168T3 (fr)
GR (1)	GR3020045T3 (fr)
RU (1)	RU2114624C1 (fr)
SG (1)	SG48779A1 (fr)
UA (1)	UA27099C2 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6828415B2 (en)	1993-02-19	2004-12-07	Zentaris Gmbh	Oligopeptide lyophilisate, their preparation and use
FR2729050A1 (fr) *	1995-02-23	1996-07-12	Oreal	Compositions resistant a la degradation microbienne
US6278004B1 (en)	1996-11-06	2001-08-21	Aventis Pharma Deutschland Gmbh	Stabilized phospholipidic composition
DE10028638A1 (de)	2000-06-09	2001-12-20	Schuelke & Mayr Gmbh	Lagerstabile Zusammensetzungen von Glycerinmonoalkylethern
US7041302B2 (en)	2001-01-09	2006-05-09	Biother Corporation	Therapeutic modulation of the tumor inflammatory response
DE10313272A1 (de) *	2003-03-24	2004-10-21	Baxter Healthcare S.A.	Verwendung von Miltefosine zur Behandlung von aktinischer oder multiplen aktinischer Keratosen
CN102596203B (zh) *	2009-07-09	2014-11-05	P.孟	烷基磷酸胆碱的液体药物形式及其制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5008294A (en) *	1985-02-11	1991-04-16	Chemex Pharmaceuticals, Inc.	Methods of treating tumors with compositions of catecholic butanes
DE3343530A1 (de) *	1983-12-01	1985-06-13	Max Planck Gesellschaft	Arzneimittel mit verbesserter penetration der gewebsmembran
IE59778B1 (en) *	1985-12-04	1994-04-06	Max Planck Gesellschaft	Medicament with anti-tumour action containing hexadecylphosphocholine
EP0419998A3 (en) *	1989-09-27	1991-10-23	Asta Pharma Aktiengesellschaft	Use of alkylphosphonic acid derivatives for the treatment of psoriasis

1992
- 1992-10-23 DE DE4235911A patent/DE4235911A1/de not_active Withdrawn
1993
- 1993-09-13 DK DK93114672.4T patent/DK0593897T3/da active
- 1993-09-13 AT AT93114672T patent/ATE136784T1/de active
- 1993-09-13 SG SG1996001594A patent/SG48779A1/en unknown
- 1993-09-13 DE DE59302251T patent/DE59302251D1/de not_active Expired - Lifetime
- 1993-09-13 ES ES93114672T patent/ES2086168T3/es not_active Expired - Lifetime
- 1993-09-13 EP EP93114672A patent/EP0593897B1/fr not_active Expired - Lifetime
- 1993-10-19 EG EG66893A patent/EG20234A/xx active
- 1993-10-19 US US08/137,964 patent/US5446033A/en not_active Expired - Lifetime
- 1993-10-20 CN CN93119330A patent/CN1052878C/zh not_active Expired - Lifetime
- 1993-10-21 UA UA93002241A patent/UA27099C2/uk unknown
- 1993-10-21 JP JP5263455A patent/JPH06227987A/ja active Pending
- 1993-10-22 RU RU93048332A patent/RU2114624C1/ru active
- 1993-10-22 CA CA002109053A patent/CA2109053C/fr not_active Expired - Fee Related
1996
- 1996-05-27 GR GR960401408T patent/GR3020045T3/el unknown

Also Published As

Publication number	Publication date
ATE136784T1 (de)	1996-05-15
CN1052878C (zh)	2000-05-31
DE59302251D1 (de)	1996-05-23
RU2114624C1 (ru)	1998-07-10
EP0593897A1 (fr)	1994-04-27
ES2086168T3 (es)	1996-06-16
CA2109053A1 (fr)	1994-04-24
CA2109053C (fr)	2004-02-10
EP0593897B1 (fr)	1996-04-17
DE4235911A1 (de)	1994-04-28
CN1090174A (zh)	1994-08-03
US5446033A (en)	1995-08-29
EG20234A (en)	1998-05-31
GR3020045T3 (en)	1996-08-31
SG48779A1 (en)	1998-05-18
JPH06227987A (ja)	1994-08-16
UA27099C2 (uk)	2000-02-28

Publication	Publication Date	Title
AU4717189A (en)	1990-06-28	Low volatility amine salts of pesticides
EP0156924A4 (fr)	1986-10-02	Composition chimiquement active contenant des ions ferreux.
AU656493B2 (en)	1995-02-02	Regulation of immunoglobin production by interleukin-4 and interleukin-9
ATE136784T1 (de)	1996-05-15	Stabilisierte alkylphosphocholinlösungen in glycerinalkylethern
SE8404930D0 (sv)	1984-10-02	Aqueous compositions containing stabilized enzymes
DE69002697D1 (de)	1993-09-16	Carboplatinzusammensetzung.
DE3279616D1 (en)	1989-05-24	Stable oil-in-water dispersions
ES460473A1 (es)	1978-05-01	Procedimiento para la obtencion de preparados cosmeticos.
DE2962232D1 (en)	1982-04-01	The use of citric acid esters in cosmetic preparations
RU93048332A (ru)	1996-11-10	Состав на основе гексадецилфосфохолина, способ его получения, лекарственное средство
ATE58479T1 (de)	1990-12-15	Albumin-komplex.
DK0419165T3 (da)	1994-05-02	Konserveringsmiddel til anvendelse i ophthalmiske opløsninger
ATE60903T1 (de)	1991-03-15	Stabile, waessrige vincristinsulfatloesung.
MY100078A (en)	1989-08-18	Improvements relating to the expansion of tobacco.
AU535779B2 (en)	1984-04-05	Amplifier with optical isolator in feedback path
SE8403110L (sv)	1984-12-10	Stabiliserad antralinkomposition och sett att stabilisera antralin
IE812355L (en)	1982-04-09	Prostaglandins
JPS5391682A (en)	1978-08-11	Semiconductor laser
ES483822A1 (es)	1980-04-16	Procedimiento para la preparacion de nuevas sales estables
ATE31623T1 (de)	1988-01-15	Injizierbare zusammensetzungen von bbm-928a.
JPS53121729A (en)	1978-10-24	Phenoxyphenoxypropionic acid derivatives and herbicides containing the same
JPS5570940A (en)	1980-05-28	Magnetic recording media
JPS6463504A (en)	1989-03-09	Controller against termite