DK0594772T3 - - Google Patents

Info

Publication number: DK0594772T3
Authority: DK; Denmark
Prior art keywords: carrier molecule; attached; group; reagents; divinyl sulfone
Prior art date: 1991-07-04

Application number

DK92916161.0T

Other languages

Danish (da)

English (en)

Inventor

Allan Otto Fog Lihme

Thomas Boenisch

Original Assignee

Immunodex K S

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-07-04

Filing date

1992-06-29

Publication date

1997-02-24

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26065568&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0594772(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1991-07-04 Priority claimed from DK911309A external-priority patent/DK130991D0/da

1992-06-29 Application filed by Immunodex K S filed Critical Immunodex K S

1997-02-24 Application granted granted Critical

1997-02-24 Publication of DK0594772T3 publication Critical patent/DK0594772T3/da

Links

239000003153 chemical reaction reagent Substances 0.000 abstract 3
AFOSIXZFDONLBT-UHFFFAOYSA-N divinyl sulfone Chemical compound C=CS(=O)(=O)C=C AFOSIXZFDONLBT-UHFFFAOYSA-N 0.000 abstract 3
125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 abstract 3
238000001514 detection method Methods 0.000 abstract 2
238000000034 method Methods 0.000 abstract 2
229920002307 Dextran Polymers 0.000 abstract 1
108090000790 Enzymes Proteins 0.000 abstract 1
102000004190 Enzymes Human genes 0.000 abstract 1
239000000427 antigen Substances 0.000 abstract 1
108091007433 antigens Proteins 0.000 abstract 1
102000036639 antigens Human genes 0.000 abstract 1
230000021615 conjugation Effects 0.000 abstract 1
229940079593 drug Drugs 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
239000000975 dye Substances 0.000 abstract 1
229940088598 enzyme Drugs 0.000 abstract 1
238000000684 flow cytometry Methods 0.000 abstract 1
125000000524 functional group Chemical group 0.000 abstract 1
150000004676 glycans Chemical class 0.000 abstract 1
229940088597 hormone Drugs 0.000 abstract 1
239000005556 hormone Substances 0.000 abstract 1
238000009396 hybridization Methods 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
238000003364 immunohistochemistry Methods 0.000 abstract 1
125000005647 linker group Chemical group 0.000 abstract 1
229920001282 polysaccharide Polymers 0.000 abstract 1
239000005017 polysaccharide Substances 0.000 abstract 1
238000002360 preparation method Methods 0.000 abstract 1
108090000623 proteins and genes Proteins 0.000 abstract 1
238000000746 purification Methods 0.000 abstract 1
238000011002 quantification Methods 0.000 abstract 1
239000000523 sample Substances 0.000 abstract 1
238000000926 separation method Methods 0.000 abstract 1
239000000126 substance Substances 0.000 abstract 1
125000003396 thiol group Chemical group [H]S* 0.000 abstract 1

Classifications

- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54353—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent

Landscapes

Health & Medical Sciences (AREA)
Immunology (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Biomedical Technology (AREA)
Chemical & Material Sciences (AREA)
Hematology (AREA)
Urology & Nephrology (AREA)
Physics & Mathematics (AREA)
Microbiology (AREA)
Cell Biology (AREA)
Food Science & Technology (AREA)
Medicinal Chemistry (AREA)
Biotechnology (AREA)
Analytical Chemistry (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
General Physics & Mathematics (AREA)
Pathology (AREA)
Peptides Or Proteins (AREA)
Cephalosporin Compounds (AREA)
Polysaccharides And Polysaccharide Derivatives (AREA)
Compositions Of Macromolecular Compounds (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Graft Or Block Polymers (AREA)
Saccharide Compounds (AREA)
Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
Immobilizing And Processing Of Enzymes And Microorganisms (AREA)

DK92916161.0T 1991-07-04 1992-06-29 DK0594772T3 (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DK911309A DK130991D0 (da)	1991-07-04	1991-07-04	Polymere konjugater
US07/789,757 US5543332A (en)	1991-07-04	1991-11-08	Water-soluble, polymer-based reagents and conjugates comprising moieties derived from divinyl sulfone

Publications (1)

Publication Number	Publication Date
DK0594772T3 true DK0594772T3 (fr)	1997-02-24

Family

ID=26065568

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK92916161.0T DK0594772T3 (fr)	1991-07-04	1992-06-29

Country Status (12)

Country	Link
EP (1)	EP0594772B1 (fr)
JP (1)	JP3340434B2 (fr)
AT (1)	ATE142021T1 (fr)
AU (1)	AU667051B2 (fr)
CA (1)	CA2112992C (fr)
DE (1)	DE69213240T2 (fr)
DK (1)	DK0594772T3 (fr)
ES (1)	ES2094920T3 (fr)
FI (1)	FI115413B (fr)
GR (1)	GR3021806T3 (fr)
NO (1)	NO315443B1 (fr)
WO (1)	WO1993001498A1 (fr)

Families Citing this family (86)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6552170B1 (en) *	1990-04-06	2003-04-22	Amgen Inc.	PEGylation reagents and compounds formed therewith
US5773227A (en) *	1993-06-23	1998-06-30	Molecular Probes, Inc.	Bifunctional chelating polysaccharides
US5446090A (en) *	1993-11-12	1995-08-29	Shearwater Polymers, Inc.	Isolatable, water soluble, and hydrolytically stable active sulfones of poly(ethylene glycol) and related polymers for modification of surfaces and molecules
JPH10500310A (ja) *	1994-05-19	1998-01-13	ダコアクティーゼルスカブ	淋菌及びトラコーマクラミジアの検出のためのｐｎａプローブ
US5888733A (en) *	1995-11-16	1999-03-30	Dako A/S	In situ hybridization to detect specific nucleic acid sequences in eucaryotic samples
US5747639A (en) *	1996-03-06	1998-05-05	Amgen Boulder Inc.	Use of hydrophobic interaction chromatography to purify polyethylene glycols
US6309646B1 (en) *	1996-05-09	2001-10-30	The Henry M. Jackson Foundation For The Advancement Of Military Medicine	Protein-polysaccharide conjugate vaccines and other immunological reagents prepared using homobifunctional and heterobifunctional vinylsulfones, and processes for preparing the conjugates
TW555765B (en)	1996-07-09	2003-10-01	Amgen Inc	Low molecular weight soluble tumor necrosis factor type-I and type-II proteins
GB9624165D0 (en)	1996-11-19	1997-01-08	Amdex A S	Use of nucleic acids bound to carrier macromolecules
WO1998024463A2 (fr)	1996-12-06	1998-06-11	Amgen Inc.	Therapie combinatoire utilisant une proteine de liaison du facteur de necrose tumorale (tnf) dans le traitement de maladies induites par le tnf
US6709873B1 (en) *	1997-04-09	2004-03-23	Isodiagnostika Inc.	Method for production of antibodies to specific sites of rapamycin
US5994089A (en) *	1997-05-16	1999-11-30	Coulter International Corp.	Simultaneous analyses of white blood cell subsets using multi-color, multi-intensity fluorescent markers in flow cytometry
US6066446A (en) *	1997-12-19	2000-05-23	Nen Life Science Products, Inc.	Assay member and method for its manufacture
WO1999040438A1 (fr) *	1998-02-03	1999-08-12	Synbiotics Corporation	Dispositifs et procedes de mesure des titres d'anticorps immunoprotecteurs
PT1101115E (pt) *	1998-07-30	2004-09-30	Oakville Trading Hong Kong Ltd	Metodo para preparar conjugados reticulados soluveis em agua
US6686454B1 (en) *	1998-10-09	2004-02-03	Isotechnika, Inc.	Antibodies to specific regions of cyclosporine related compounds
WO2000022000A1 (fr) *	1998-10-09	2000-04-20	Isotechnika, Inc.	Procede de production d'anticorps diriges contre des regions specifiques de cyclosporine et de metabolites de cyclosporine
US6660843B1 (en)	1998-10-23	2003-12-09	Amgen Inc.	Modified peptides as therapeutic agents
JP3781934B2 (ja)	1999-12-22	2006-06-07	株式会社ニチレイバイオサイエンス	酵素−タンパク質複合体
DE10039112A1 (de) *	2000-08-07	2002-03-07	Pe Diagnostik Gmbh	Verfahren zum Herstellen von Antikörper aus einer verunreinigten Antigenlösung
GB0029617D0 (en) *	2000-12-05	2001-01-17	Norchip As	Ligand detection method
DK2336167T3 (da)	2001-03-14	2019-09-02	Dako Denmark As	MHC-molekylkonstrukter og deres anvendelse til diagnose og terapi
US7034127B2 (en) *	2002-07-02	2006-04-25	Genzyme Corporation	Hydrophilic biopolymer-drug conjugates, their preparation and use
CA2433479A1 (fr)	2002-07-22	2004-01-22	F. Hoffmann-La Roche Ag	Conjugue d'un tissu alkalin-phosphatase et dextran non-specifique, methode de fabrication et utilisation
EP1405907A3 (fr) *	2002-07-22	2004-10-13	Roche Diagnostics GmbH	Conjugué de dextrane et de tissue non-spécifique phosphatase alcaline, procédé de fabrication et utilisation
WO2005062048A1 (fr) *	2003-12-01	2005-07-07	Dade Behring Marburg Gmbh	Procede de detection homogene
EP1692515A1 (fr) *	2003-12-01	2006-08-23	Dade Behring Marburg GmbH	Conjugues et leur utilisation dans des procedes de detection
JP4949038B2 (ja)	2003-12-01	2012-06-06	ダコデンマークアクティーゼルスカブ	免疫組織化学的検出のための方法および組成物
GB0426822D0 (en)	2004-12-07	2005-01-12	Precisense As	Sensor for detection of glucose
GB0426823D0 (en)	2004-12-07	2005-01-12	Precisense As	Sensor for detection of glucose
NZ564222A (en)	2005-06-14	2011-10-28	Taigen Biotechnology Co Ltd	Pyrimidine compounds
US8193206B2 (en)	2005-06-14	2012-06-05	Taigen Biotechnology Co., Ltd.	Pyrimidine compounds
DE112006003813T5 (de)	2006-03-20	2009-01-22	Inverness Medical Switzerland Gmbh	Wasserlösliche Konjugate zur elektrochemischen Detektion
WO2008116468A2 (fr) *	2007-03-26	2008-10-02	Dako Denmark A/S	Complexes peptidiques du cmh et leurs utilisations dans des maladies infectieuses
EP3620465B1 (fr)	2007-07-03	2025-02-19	Dako Denmark A/S	Procédés améliorés pour produire, marquer et utiliser des multimères du cmh
US10611818B2 (en)	2007-09-27	2020-04-07	Agilent Technologies, Inc.	MHC multimers in tuberculosis diagnostics, vaccine and therapeutics
DK2254592T3 (da)	2008-02-28	2019-09-09	Dako Denmark As	MHC-multimerer til Borrelia-diagnostik og sygdom
DK2268635T3 (en)	2008-04-21	2015-09-14	Taigen Biotechnology Co Ltd	Heterocyclic Compounds
WO2010009735A2 (fr)	2008-07-23	2010-01-28	Dako Denmark A/S	Analyse et réparation combinatoires
DK2334703T3 (en)	2008-09-17	2015-10-05	Innate Pharma	Configurations and methods for detection of tlr3
GB0817244D0 (en)	2008-09-20	2008-10-29	Univ Cardiff	Use of a protein kinase inhibitor to detect immune cells, such as T cells
US11992518B2 (en)	2008-10-02	2024-05-28	Agilent Technologies, Inc.	Molecular vaccines for infectious disease
WO2010037402A1 (fr)	2008-10-02	2010-04-08	Dako Denmark A/S	Vaccins moléculaires contre les maladies infectieuses
US9023834B2 (en)	2008-11-13	2015-05-05	Taigen Biotechnology Co., Ltd.	Lyophilization formulation
EP2270506A3 (fr) *	2009-07-02	2011-03-09	Amic AB	Conjugué étiqueté amplifié pour l'utilisation dans des immunoessais
EP2494073B1 (fr)	2009-10-26	2017-11-29	AGCT GmbH	Conjugués de nucléotides et méthodes d'utilisation associées
US10273541B2 (en)	2012-08-14	2019-04-30	10X Genomics, Inc.	Methods and systems for processing polynucleotides
US11591637B2 (en)	2012-08-14	2023-02-28	10X Genomics, Inc.	Compositions and methods for sample processing
US9951386B2 (en)	2014-06-26	2018-04-24	10X Genomics, Inc.	Methods and systems for processing polynucleotides
US9701998B2 (en)	2012-12-14	2017-07-11	10X Genomics, Inc.	Methods and systems for processing polynucleotides
AU2013302756C1 (en)	2012-08-14	2018-05-17	10X Genomics, Inc.	Microcapsule compositions and methods
US10323279B2 (en)	2012-08-14	2019-06-18	10X Genomics, Inc.	Methods and systems for processing polynucleotides
US10752949B2 (en)	2012-08-14	2020-08-25	10X Genomics, Inc.	Methods and systems for processing polynucleotides
US10584381B2 (en)	2012-08-14	2020-03-10	10X Genomics, Inc.	Methods and systems for processing polynucleotides
CA2894694C (fr)	2012-12-14	2023-04-25	10X Genomics, Inc.	Procedes et systemes pour le traitement de polynucleotides
US10533221B2 (en)	2012-12-14	2020-01-14	10X Genomics, Inc.	Methods and systems for processing polynucleotides
KR20200140929A (ko)	2013-02-08	2020-12-16	10엑스 제노믹스, 인크.	폴리뉴클레오티드 바코드 생성
JP6353446B2 (ja)	2013-06-28	2018-07-04	国立大学法人九州大学	タンパク質−ポリマ複合体、ＴＧａｓｅ基質含有ポリマ、ＴＧａｓｅ基質含有モノマ、タンパク質−ポリマ複合体の製造方法、および固液の界面あるいは界面近傍でタンパク質機能を高める方法
BR112016023625A2 (pt)	2014-04-10	2018-06-26	10X Genomics, Inc.	dispositivos fluídicos, sistemas e métodos para encapsular e particionar reagentes, e aplicações dos mesmos
WO2015188839A2 (fr)	2014-06-13	2015-12-17	Immudex Aps	Détection générale et isolement de cellules spécifiques par liaison de molécules marquées
US12312640B2 (en)	2014-06-26	2025-05-27	10X Genomics, Inc.	Analysis of nucleic acid sequences
CA2953469A1 (fr)	2014-06-26	2015-12-30	10X Genomics, Inc.	Analyse de sequences d'acides nucleiques
WO2015200893A2 (fr)	2014-06-26	2015-12-30	10X Genomics, Inc.	Procédés d'analyse d'acides nucléiques provenant de cellules individuelles ou de populations de cellules
JP6769969B2 (ja)	2015-01-12	2020-10-14	１０エックスジェノミクス，インコーポレイテッド	核酸配列決定ライブラリーを作製するためのプロセス及びシステム、並びにこれらを使用して作製したライブラリー
EP3262407B1 (fr)	2015-02-24	2023-08-30	10X Genomics, Inc.	Procédés et systèmes de traitement de cloisonnement
JP6954899B2 (ja)	2015-12-04	2021-10-27	１０エックスゲノミクス，インコーポレイテッド	核酸の解析のための方法及び組成物
CA3017412A1 (fr)	2016-03-15	2017-09-21	Mipsalus Aps	Methode de determination qualitative ou quantitative de la presence d'un analyte dans un echantillon
US10815525B2 (en)	2016-12-22	2020-10-27	10X Genomics, Inc.	Methods and systems for processing polynucleotides
US10550429B2 (en)	2016-12-22	2020-02-04	10X Genomics, Inc.	Methods and systems for processing polynucleotides
US10011872B1 (en)	2016-12-22	2018-07-03	10X Genomics, Inc.	Methods and systems for processing polynucleotides
EP4029939B1 (fr)	2017-01-30	2023-06-28	10X Genomics, Inc.	Procédés et systèmes de codage à barres de cellules individuelles sur la base de gouttelettes
US10400235B2 (en)	2017-05-26	2019-09-03	10X Genomics, Inc.	Single cell analysis of transposase accessible chromatin
EP3445876B1 (fr)	2017-05-26	2023-07-05	10X Genomics, Inc.	Analyse de la chromatine accessible par une transposase d'une cellule unique
SG11201913654QA (en)	2017-11-15	2020-01-30	10X Genomics Inc	Functionalized gel beads
US10829815B2 (en)	2017-11-17	2020-11-10	10X Genomics, Inc.	Methods and systems for associating physical and genetic properties of biological particles
SG11202007686VA (en)	2018-02-12	2020-09-29	10X Genomics Inc	Methods characterizing multiple analytes from individual cells or cell populations
CN112262218B (zh)	2018-04-06	2024-11-08	10X基因组学有限公司	用于单细胞处理中的质量控制的系统和方法
WO2019200326A1 (fr)	2018-04-13	2019-10-17	Rarecyte, Inc.	Kits pour le marquage de biomarqueurs et procédés d'utilisation de ceux-ci
WO2019217758A1 (fr)	2018-05-10	2019-11-14	10X Genomics, Inc.	Procédés et systèmes de génération de banque moléculaire
WO2020127222A2 (fr)	2018-12-17	2020-06-25	Immudex Aps	Panneau comprenant des multimères de borrelia cmh
WO2021152178A1 (fr)	2020-01-31	2021-08-05	Cell.Copedia GmbH	Procédés d'isolement d'une entité biologique
US12449419B1 (en)	2020-02-12	2025-10-21	10X Genomics, Inc.	Methods for detecting binding of peptide-MHC monomers to T cells
CA3186062A1 (fr)	2020-08-10	2022-02-17	Marion BENEZECH	Detection de mica et de micb a la surface de cellules a l'aide d'anticorps
CN111965341B (zh) *	2020-08-10	2023-04-11	武汉菲恩生物科技有限公司	一种基于葡聚糖的HRP-羊抗鼠IgG标记抗体及其制备方法
KR20230165913A (ko)	2021-04-05	2023-12-05	이나뜨 파르마 에스.에이.	면역조직화학 방법 및 kir3dl2-특이적 시약
CN115537410A (zh) *	2022-09-27	2022-12-30	凯莱英医药化学（阜新）技术有限公司	酶固定化载体及其制备方法、固定化酶及其制备方法和应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2712344C2 (de) *	1977-03-21	1982-09-23	Hans Dr. 4803 Steinhagen Bünemann	Löslicher Komplexbildner für die affinitätsspezifische Trennung von Nukleinsäuren
SE7812237L (sv) *	1978-11-28	1980-05-29	Pharmacia Diagnostics Ab	Koncentrationsbestemning av substanser med formaga att biospecifikt binda molekyler med biologiskt ursprung
FR2453847B1 (fr) *	1979-04-13	1985-08-16	Anvar	Procede pour l'obtention d'ampholytes porteurs utilisables dans les diverses techniques d'electrofocalisation
US4752339A (en) *	1983-10-31	1988-06-21	Hi-Tek Polymers, Inc.	Thixotropic aqueous solutions containing a divinylsulfone-crosslinked polygalactomannan gum
US4780409A (en) *	1985-05-02	1988-10-25	Genetic Systems Corporation	Thermally induced phase separation immunoassay
US4778751A (en) *	1986-05-12	1988-10-18	Diagnostic Products Corporation	Method for measuring antigens or antibodies in biological fluids using ligand labeled antigens or ligand labeled antibodies
CA1304682C (fr) *	1986-11-19	1992-07-07	Nobuo Monji	Dosage immunologique permettant de mesurer les concentrations par affinite sur membrane
AU609241B2 (en) *	1988-01-29	1991-04-26	Abbott Laboratories	Ion-capture assays and devices
CA1341592C (fr) *	1989-07-07	2009-04-14	Abbott Laboratories	Reactifs pour la capture d'ions et methodes pour effectuer des depistages de liaison

1992
- 1992-06-29 DK DK92916161.0T patent/DK0594772T3/da active
- 1992-06-29 WO PCT/DK1992/000206 patent/WO1993001498A1/fr not_active Ceased
- 1992-06-29 CA CA002112992A patent/CA2112992C/fr not_active Expired - Lifetime
- 1992-06-29 AT AT92916161T patent/ATE142021T1/de active
- 1992-06-29 DE DE69213240T patent/DE69213240T2/de not_active Expired - Lifetime
- 1992-06-29 EP EP92916161A patent/EP0594772B1/fr not_active Expired - Lifetime
- 1992-06-29 JP JP50189993A patent/JP3340434B2/ja not_active Expired - Lifetime
- 1992-06-29 AU AU23489/92A patent/AU667051B2/en not_active Expired
- 1992-06-29 ES ES92916161T patent/ES2094920T3/es not_active Expired - Lifetime
1994
- 1994-01-04 FI FI940023A patent/FI115413B/fi not_active IP Right Cessation
- 1994-01-04 NO NO19940030A patent/NO315443B1/no not_active IP Right Cessation
1996
- 1996-11-28 GR GR960403197T patent/GR3021806T3/el unknown

Also Published As

Publication number	Publication date
JP3340434B2 (ja)	2002-11-05
FI940023A7 (fi)	1994-02-25
NO940030D0 (no)	1994-01-04
GR3021806T3 (en)	1997-02-28
CA2112992C (fr)	2002-06-11
ES2094920T3 (es)	1997-02-01
EP0594772A1 (fr)	1994-05-04
FI115413B (fi)	2005-04-29
DE69213240T2 (de)	1997-04-24
DE69213240D1 (de)	1996-10-02
NO940030L (no)	1994-03-03
EP0594772B1 (fr)	1996-08-28
ATE142021T1 (de)	1996-09-15
AU2348992A (en)	1993-02-11
FI940023A0 (fi)	1994-01-04
NO315443B1 (no)	2003-09-01
WO1993001498A1 (fr)	1993-01-21
JPH06509167A (ja)	1994-10-13
AU667051B2 (en)	1996-03-07
CA2112992A1 (fr)	1993-01-21

Publication	Publication Date	Title
DK0594772T3 (fr)	1997-02-24
US9134302B2 (en)	2015-09-15	Analyte detection utilizing polynucleotide sequences, composition, process and kit
EP0154884A2 (fr)	1985-09-18	Produit conjugué d'acide nucléique et protéine
US5728588A (en)	1998-03-17	Coating of hydrophobic surfaces to render them protein resistant while permitting covalent attachment of specific ligands
US5650334A (en)	1997-07-22	Fluorescent labelling compositions and methods for their use
Nakamura et al.	1993	Detection and removal of Escherichia coli using fluorescein isothiocyanate conjugated monoclonal antibody immobilized on bacterial magnetic particles
US4824775A (en)	1989-04-25	Cells labeled with multiple Fluorophores bound to a nucleic acid carrier
JP3124018B2 (ja)	2001-01-15	結合アッセイ用固相の調製方法
CN1875116B (zh)	2014-01-29	可溶性分析物的检测和扩增
CA2336564A1 (fr)	2000-02-10	Procede de preparation de conjugues reticules, solubles dans l'eau
EP0040365B1 (fr)	1985-08-21	Méthode d'essai comportant des réactions d'affinité biospécifique
US4670380A (en)	1987-06-02	Assays utilizing labeled nucleic acid probes
WO2007137418A1 (fr)	2007-12-06	Éléments de marquage à squelette polymérique
Ngo	1986	Facile activation of Sepharose hydroxyl groups by 2-fluoro-1 methylpyridinium toluene-4-sulfonate: preparation of affinity and covalent chromatographic matrices
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US5225516A (en)	1993-07-06	Polymers
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