DK0595948T3 - Gærstammer med stabil integration af heterologe gener - Google Patents

Gærstammer med stabil integration af heterologe gener

Info

Publication number
DK0595948T3
DK0595948T3 DK92916070.3T DK92916070T DK0595948T3 DK 0595948 T3 DK0595948 T3 DK 0595948T3 DK 92916070 T DK92916070 T DK 92916070T DK 0595948 T3 DK0595948 T3 DK 0595948T3
Authority
DK
Denmark
Prior art keywords
pct
yeast strains
heterologous genes
stable integration
heterologous
Prior art date
Application number
DK92916070.3T
Other languages
English (en)
Inventor
Denis Pompon
Christophe Cullin
Gilles Truan
Philippe Urban
Piotr Slonimski
Original Assignee
Centre Nat Rech Scient
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre Nat Rech Scient filed Critical Centre Nat Rech Scient
Application granted granted Critical
Publication of DK0595948T3 publication Critical patent/DK0595948T3/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0036—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on NADH or NADPH (1.6)
    • C12N9/0038—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on NADH or NADPH (1.6) with a heme protein as acceptor (1.6.2)
    • C12N9/0042—NADPH-cytochrome P450 reductase (1.6.2.4)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/795—Porphyrin- or corrin-ring-containing peptides
    • C07K14/80—Cytochromes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/16—Yeasts; Culture media therefor
    • C12N1/18—Baker's yeast; Brewer's yeast
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Mycology (AREA)
  • Biophysics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Botany (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Distillation Of Fermentation Liquor, Processing Of Alcohols, Vinegar And Beer (AREA)
DK92916070.3T 1991-07-15 1992-07-15 Gærstammer med stabil integration af heterologe gener DK0595948T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9108884A FR2679249B1 (fr) 1991-07-15 1991-07-15 Souches de levure avec integration stable de genes heterologues.

Publications (1)

Publication Number Publication Date
DK0595948T3 true DK0595948T3 (da) 1997-12-15

Family

ID=9415092

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92916070.3T DK0595948T3 (da) 1991-07-15 1992-07-15 Gærstammer med stabil integration af heterologe gener

Country Status (11)

Country Link
US (1) US5635369A (da)
EP (1) EP0595948B1 (da)
AT (1) ATE153381T1 (da)
AU (1) AU663105B2 (da)
CA (1) CA2113477C (da)
DE (1) DE69219894T2 (da)
DK (1) DK0595948T3 (da)
ES (1) ES2103955T3 (da)
FR (1) FR2679249B1 (da)
GR (1) GR3024503T3 (da)
WO (1) WO1993002200A1 (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2738840B1 (fr) * 1995-09-19 1997-10-31 Rhone Poulenc Rorer Sa Souches de levures genetiquement modifiees
US5831018A (en) * 1997-02-18 1998-11-03 Incyte Pharmaceuticals, Inc. Human cytochrome B5
AU5060200A (en) * 1999-04-24 2000-11-10 Max-Delbruck-Centrum Fur Molekulare Medizin Nucleic acid sequences from (candida) yeasts which code cytochrome b5 polypeptides
FR2810337B1 (fr) * 2000-06-20 2002-09-13 Univ Clermont Auvergne Micro-organismes actifs dans l'environnement digestif
US6943001B2 (en) * 2001-08-03 2005-09-13 Diversa Corporation Epoxide hydrolases, nucleic acids encoding them and methods for making and using them
US6979733B2 (en) * 2001-08-03 2005-12-27 Diversa Corporation Epoxide hydrolases, nucleic acids encoding them and methods of making and using them
ATE315660T1 (de) * 2002-05-16 2006-02-15 Bavarian Nordic As Intergene regionen als insertionsstellen im genom von modifiziertem vaccinia virus ankara (mva)
WO2010134096A2 (en) 2009-05-19 2010-11-25 Premas Biotech Pvt. Ltd Yeast strain expressing modified human cytochrome p450 reductase and/or cytochrome p450 gene
WO2010134095A2 (en) 2009-05-19 2010-11-25 Premas Biotech Pvt. Ltd Yeast strain expressing modified human cytochrome p450 reductase and/or cytochrome p450 gene
US20120156761A1 (en) 2009-07-02 2012-06-21 Verdezyne, Inc. Biological methods for preparing adipic acid
US8728798B2 (en) 2011-05-03 2014-05-20 Verdezyne, Inc. Biological methods for preparing adipic acid
US8343752B2 (en) 2011-05-03 2013-01-01 Verdezyne, Inc. Biological methods for preparing adipic acid
FR2991340B1 (fr) * 2012-06-01 2016-02-19 Lesaffre & Cie Procede d'obtention de souches de levure ameliorees par modification genetique et croisement

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU5954486A (en) * 1985-05-21 1986-12-24 Biotechnica International Inc. Yeast expressing gluocoamylase
DK293787A (da) * 1986-06-10 1987-12-11 Transgene Sa Ekspression af en amyloglucosidase
EP0382332A3 (en) * 1989-01-06 1990-11-14 Collaborative Research Inc. Improved supersecreting mutants of saccharomyces cerevisiae
CA2017176A1 (en) * 1989-05-22 1990-11-22 Yoshitomi Pharmaceutical Industries Ltd. Albumin gene-containing plasmid, transformant carrying same, production of such transformant and production of albumin

Also Published As

Publication number Publication date
FR2679249A1 (fr) 1993-01-22
JPH06508761A (ja) 1994-10-06
WO1993002200A1 (fr) 1993-02-04
EP0595948B1 (fr) 1997-05-21
FR2679249B1 (fr) 1993-11-26
CA2113477C (fr) 2003-09-23
AU2387792A (en) 1993-02-23
ATE153381T1 (de) 1997-06-15
GR3024503T3 (en) 1997-11-28
CA2113477A1 (fr) 1993-02-04
JP3610410B2 (ja) 2005-01-12
DE69219894T2 (de) 1998-01-15
ES2103955T3 (es) 1997-10-01
US5635369A (en) 1997-06-03
EP0595948A1 (fr) 1994-05-11
AU663105B2 (en) 1995-09-28
DE69219894D1 (de) 1997-06-26

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