DK0610446T3 - Syntetisk peptidspecificitet af antimyelin basic protein fra cerebrospinalvæske fra dissemineret sklerose - Google Patents
Syntetisk peptidspecificitet af antimyelin basic protein fra cerebrospinalvæske fra dissemineret skleroseInfo
- Publication number
- DK0610446T3 DK0610446T3 DK93908754T DK93908754T DK0610446T3 DK 0610446 T3 DK0610446 T3 DK 0610446T3 DK 93908754 T DK93908754 T DK 93908754T DK 93908754 T DK93908754 T DK 93908754T DK 0610446 T3 DK0610446 T3 DK 0610446T3
- Authority
- DK
- Denmark
- Prior art keywords
- mbp
- residues
- synthetic peptide
- cerebrospinal fluid
- basic protein
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 5
- 201000006417 multiple sclerosis Diseases 0.000 title abstract 2
- 101710093543 Probable non-specific lipid-transfer protein Proteins 0.000 title 1
- 230000002502 anti-myelin effect Effects 0.000 title 1
- 210000001175 cerebrospinal fluid Anatomy 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 4
- 125000000539 amino acid group Chemical group 0.000 abstract 3
- 102000006386 Myelin Proteins Human genes 0.000 abstract 1
- 108010083674 Myelin Proteins Proteins 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 238000007913 intrathecal administration Methods 0.000 abstract 1
- 230000003472 neutralizing effect Effects 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4713—Autoimmune diseases, e.g. Insulin-dependent diabetes mellitus, multiple sclerosis, rheumathoid arthritis, systemic lupus erythematosus; Autoantigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Zoology (AREA)
- Diabetes (AREA)
- Rheumatology (AREA)
- Rehabilitation Therapy (AREA)
- Hospice & Palliative Care (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Psychiatry (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA002053799A CA2053799C (en) | 1991-10-22 | 1991-10-22 | Synthetic peptide specificity of anti-myelin basic protein from multiple sclerosis cerebrospinal fluid |
| PCT/CA1992/000448 WO1993008212A1 (en) | 1991-10-22 | 1992-10-15 | Synthetic peptide specificity of anti-myelin basic protein from multiple sclerosis cerebrospinal fluid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0610446T3 true DK0610446T3 (da) | 2003-07-14 |
Family
ID=4148603
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK93908754T DK0610446T3 (da) | 1991-10-22 | 1992-10-15 | Syntetisk peptidspecificitet af antimyelin basic protein fra cerebrospinalvæske fra dissemineret sklerose |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP0610446B1 (da) |
| AT (1) | ATE236193T1 (da) |
| AU (1) | AU2750092A (da) |
| CA (1) | CA2053799C (da) |
| DE (1) | DE69232987T2 (da) |
| DK (1) | DK0610446T3 (da) |
| ES (1) | ES2196007T3 (da) |
| FI (1) | FI111050B (da) |
| NO (1) | NO310513B1 (da) |
| NZ (1) | NZ244807A (da) |
| RU (1) | RU2121850C1 (da) |
| WO (1) | WO1993008212A1 (da) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5817629A (en) * | 1991-10-22 | 1998-10-06 | The Governors Of The University Of Alberta | Peptide specificity of anti-myelin basic protein and the administration of myelin basic protein peptides to multiple sclerosis patients |
| US6252040B1 (en) | 1991-10-22 | 2001-06-26 | The Governors Of The University Of Alberta | Peptide specificity of anti-myelin basic protein and the administration of myelin basic protein peptides to multiple sclerosis patients |
| BR9509438A (pt) * | 1994-10-25 | 1997-12-23 | Immulogic Pharma Corp | Composições e tratamento para a esclerose múltipla |
| DE69525544T2 (de) | 1994-11-18 | 2002-08-22 | Neurocrine Biosciences, Inc. | Peptidanaloga des menschlichen myelinbasischen proteins mit substitution in position 91 zur behandlung von multipler sklerose |
| US6379670B1 (en) | 1994-11-18 | 2002-04-30 | Neurocrine Biosciences, Inc. | Methods for treatment of multiple sclerosis using peptide analogs of human myelin basic protein |
| US6251396B1 (en) | 1994-11-18 | 2001-06-26 | Neurocrine Biosciences, Inc. | Methods for treatment of multiple sclerosis using peptide analogs of human myelin basic protein |
| US6329499B1 (en) | 1994-11-18 | 2001-12-11 | Neurocrine Biosciences, Inc. | Methods for treatment of multiple sclerosis using peptide analogues of human myelin basic protein |
| WO1996028470A2 (en) * | 1995-03-09 | 1996-09-19 | Neurocrine Biosciences, Inc. | Peptide analogues of human myelin basic protein useful in treating multiple sclerosis |
| CA2494338C (en) * | 1997-04-04 | 2007-07-17 | The Governors Of The University Of Alberta | Peptide specificity of anti-myelin basic protein and the administration of myelin basic protein peptides to multiple sclerosis patients |
| RU2244719C1 (ru) * | 2003-07-29 | 2005-01-20 | Терентьев Александр Александрович | Композиция из пептидов, обладающая иммуномодуляторным свойством |
| RU2266297C1 (ru) * | 2004-05-12 | 2005-12-20 | Терентьев Александр Александрович | Композиция из пептидов, обладающая иммунорегуляторным свойством |
| WO2005009455A1 (fr) * | 2003-07-29 | 2005-02-03 | Terentiev Alexandr Alexandrovi | Composition de peptides presentant une propriete immunoregulatrice |
| EP1753455A2 (en) * | 2004-06-04 | 2007-02-21 | Genentech, Inc. | Method for treating multiple sclerosis |
| WO2011046462A1 (en) * | 2009-10-12 | 2011-04-21 | Angport Limited | Composition for treatment of multiple sclerosis |
| US9326773B2 (en) | 2012-01-26 | 2016-05-03 | Covidien Lp | Surgical device including buttress material |
| EP4611796A1 (en) * | 2022-11-01 | 2025-09-10 | Universität Zürich | Novel mbp peptides and their use in the treatment of multiple sclerosis |
-
1991
- 1991-10-22 CA CA002053799A patent/CA2053799C/en not_active Expired - Lifetime
-
1992
- 1992-10-15 ES ES93908754T patent/ES2196007T3/es not_active Expired - Lifetime
- 1992-10-15 AT AT93908754T patent/ATE236193T1/de not_active IP Right Cessation
- 1992-10-15 DK DK93908754T patent/DK0610446T3/da active
- 1992-10-15 DE DE69232987T patent/DE69232987T2/de not_active Expired - Lifetime
- 1992-10-15 WO PCT/CA1992/000448 patent/WO1993008212A1/en not_active Ceased
- 1992-10-15 RU RU94027578A patent/RU2121850C1/ru not_active IP Right Cessation
- 1992-10-15 AU AU27500/92A patent/AU2750092A/en not_active Abandoned
- 1992-10-15 EP EP93908754A patent/EP0610446B1/en not_active Expired - Lifetime
- 1992-10-20 NZ NZ244807A patent/NZ244807A/xx not_active IP Right Cessation
-
1994
- 1994-04-19 NO NO19941415A patent/NO310513B1/no not_active IP Right Cessation
- 1994-04-21 FI FI941860A patent/FI111050B/fi active
Also Published As
| Publication number | Publication date |
|---|---|
| CA2053799A1 (en) | 1993-04-23 |
| NO310513B1 (no) | 2001-07-16 |
| EP0610446B1 (en) | 2003-04-02 |
| FI111050B (fi) | 2003-05-30 |
| DE69232987D1 (de) | 2003-05-08 |
| WO1993008212A1 (en) | 1993-04-29 |
| EP0610446A1 (en) | 1994-08-17 |
| ATE236193T1 (de) | 2003-04-15 |
| AU2750092A (en) | 1993-05-21 |
| NZ244807A (en) | 1997-08-22 |
| RU94027578A (ru) | 1996-10-20 |
| NO941415L (da) | 1994-06-22 |
| NO941415D0 (no) | 1994-04-19 |
| CA2053799C (en) | 2002-03-12 |
| FI941860L (fi) | 1994-04-21 |
| DE69232987T2 (de) | 2004-01-29 |
| FI941860A0 (fi) | 1994-04-21 |
| RU2121850C1 (ru) | 1998-11-20 |
| ES2196007T3 (es) | 2003-12-16 |
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