DK0610697T3 - Imidazolyl-substituerede phenyleddikesyreprolinamider. - Google Patents

Imidazolyl-substituerede phenyleddikesyreprolinamider.

Info

Publication number: DK0610697T3
Authority: DK; Denmark
Prior art keywords: prolinamides; imidazolyl; substituted phenylacetic; phenylacetic acid; substituted
Prior art date: 1993-02-03

Application number

DK94100845.0T

Other languages

English (en)

Inventor

Siegfried Dr Zaiss

Stefan Dr Wohlfeil

Andreas Dr Knorr

J Dressel

Peter Dr Fey

Walter Dr Huebsch

Ulrich E Dr Mueller

Martin Dr Beuck

Johannes-Peter Dr Stasch

Matthias Dr Mueller-Gliemann

Rudolf H Dr Hanko

Thomas Dr Kraemer

Stanislav Prof Dr Kazda

Original Assignee

Bayer Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-02-03

Filing date

1994-01-21

Publication date

1997-09-15

1994-01-21 Application filed by Bayer Ag filed Critical Bayer Ag

1997-09-15 Application granted granted Critical

1997-09-15 Publication of DK0610697T3 publication Critical patent/DK0610697T3/da

Links

-1 Imidazolyl-substituted phenylacetic acid Chemical class 0.000 title abstract 3
201000001320 Atherosclerosis Diseases 0.000 abstract 1
206010020772 Hypertension Diseases 0.000 abstract 1
239000004480 active ingredient Substances 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
WLJVXDMOQOGPHL-UHFFFAOYSA-N phenylacetic acid Chemical class OC(=O)CC1=CC=CC=C1 WLJVXDMOQOGPHL-UHFFFAOYSA-N 0.000 abstract 1
235000013930 proline Nutrition 0.000 abstract 1
150000003148 prolines Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Pulmonology (AREA)
Urology & Nephrology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Vascular Medicine (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Epoxy Resins (AREA)
Peptides Or Proteins (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

DK94100845.0T 1993-02-03 1994-01-21 Imidazolyl-substituerede phenyleddikesyreprolinamider. DK0610697T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE4302957A DE4302957A1 (de)	1993-02-03	1993-02-03	Imidazolyl-substituierte Phenylessigsäureprolinamide

Publications (1)

Publication Number	Publication Date
DK0610697T3 true DK0610697T3 (da)	1997-09-15

Family

ID=6479487

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK94100845.0T DK0610697T3 (da)	1993-02-03	1994-01-21	Imidazolyl-substituerede phenyleddikesyreprolinamider.

Country Status (8)

Country	Link
US (1)	US5459156A (da)
EP (1)	EP0610697B1 (da)
JP (1)	JPH06271573A (da)
AT (1)	ATE150018T1 (da)
DE (2)	DE4302957A1 (da)
DK (1)	DK0610697T3 (da)
ES (1)	ES2099494T3 (da)
GR (1)	GR3023194T3 (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6774236B1 (en) *	1996-04-04	2004-08-10	Bayer Aktiengesellschaft	Process for the preparation of enantiomerically pure cycloalkano-indol -and azaindol -and pyrimido [1,2A]indolcarbocyclic acids and their activated derivatives
US6329342B1 (en)	1997-08-19	2001-12-11	Eli Lilly And Company	Treatment of congestive heart failure with growth hormone secretagogues
US6639076B1 (en)	1998-08-18	2003-10-28	Eli Lilly And Company	Growth hormone secretagogues
US6828331B1 (en) *	1999-02-19	2004-12-07	Eli Lilly And Company	Growth hormone secretagogues
US7125840B2 (en) *	2001-10-09	2006-10-24	Eli Lilly And Company	Substituted dipeptides as growth hormone secretagogues
US20060167268A1 (en) *	2002-04-09	2006-07-27	Eli Lilly And Company, Patent Division,	Growth hormone secretagogues
US7396846B2 (en) *	2002-04-09	2008-07-08	Eli Lilly And Company	Growth hormone secretagogues
US9845292B2 (en) *	2013-09-19	2017-12-19	MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V.	Selective FKBP51 ligands for treatment of psychiatric disorders
CN107001337B (zh) *	2015-01-13	2021-05-04	诺华股份有限公司	作为血管紧张素ii型拮抗剂的吡咯烷衍生物

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NZ190995A (en) *	1978-09-05	1982-03-09	American Cyanamid Co	Substituted omega propionyl or butyryl l-prolines and pharmaceutical compositions
US5138069A (en) *	1986-07-11	1992-08-11	E. I. Du Pont De Nemours And Company	Angiotensin II receptor blocking imidazoles
EP0515548A4 (en) *	1990-02-13	1993-03-10	Merck & Co. Inc.	Imidazole angiotensin ii antagonists incorporating a substituted benzyl element
DE4200954A1 (de) *	1991-04-26	1992-10-29	Bayer Ag	Heterocyclisch substituierte phenylessigsaeurederivate
DE4208051A1 (de) *	1992-03-13	1993-09-16	Bayer Ag	Substituierte phenylessigsaeureamide
US5401851A (en) *	1992-06-03	1995-03-28	Eli Lilly And Company	Angiotensin II antagonists

1993
- 1993-02-03 DE DE4302957A patent/DE4302957A1/de not_active Withdrawn
1994
- 1994-01-21 DK DK94100845.0T patent/DK0610697T3/da active
- 1994-01-21 AT AT94100845T patent/ATE150018T1/de not_active IP Right Cessation
- 1994-01-21 DE DE59401990T patent/DE59401990D1/de not_active Expired - Fee Related
- 1994-01-21 ES ES94100845T patent/ES2099494T3/es not_active Expired - Lifetime
- 1994-01-21 EP EP94100845A patent/EP0610697B1/de not_active Expired - Lifetime
- 1994-01-27 US US08/188,615 patent/US5459156A/en not_active Expired - Fee Related
- 1994-02-01 JP JP6027586A patent/JPH06271573A/ja active Pending
1997
- 1997-04-21 GR GR970400854T patent/GR3023194T3/el unknown

Also Published As

Publication number	Publication date
ATE150018T1 (de)	1997-03-15
DE4302957A1 (de)	1994-08-04
EP0610697A1 (de)	1994-08-17
GR3023194T3 (en)	1997-07-30
EP0610697B1 (de)	1997-03-12
ES2099494T3 (es)	1997-05-16
US5459156A (en)	1995-10-17
JPH06271573A (ja)	1994-09-27
DE59401990D1 (de)	1997-04-17

Publication	Publication Date	Title
FI942160A0 (fi)	1994-05-10	Substituoituja mono- ja bipyridyylimetyylipyridoneja
MY129973A (en)	2007-05-31	Sulphonylbenzyl-substituted pyridones.
DE10299026I1 (de)	2002-11-07	Neue Thienylcarbonsaeureester von Aminoalkoholen ihre Quaternierungsprodukte sowie die Herstellung und Verwendung dieser Verbindungen
RU94040170A (ru)	1996-10-10	Изохинолины
MY131595A (en)	2007-08-30	Heterocyclically substituted phenyl-cyclohexane- carboxylic acid derivatives
DE59300135D1 (de)	1995-05-18	Sulfonylbenzyl-substituierte Benzo- und Pyridopyridone.
ATE164159T1 (de)	1998-04-15	Substituierte triole
DE59401990D1 (de)	1997-04-17	Imidazolyl-substituierte Phenylessigsäureprolinamide
DE68901105D1 (de)	1992-05-07	Alkensaeurederivate.
ATE140703T1 (de)	1996-08-15	Diaminsalze von clavulansäure
GR3036287T3 (en)	2001-10-31	Substituted imidazo(4,5-b)pyridines and benzimidazoles as angiotensin II antagonistes.
ES2124861T3 (es)	1999-02-16	Derivados de aminoacidos y su utilizacion como inhibidores de la encefalinasa.
ATE160146T1 (de)	1997-11-15	Hetero-tricyclisch-substituierte phenyl- cyclohexan-carbonsäurederivate
FI956025A7 (fi)	1995-12-14	Menetelmä oksatsolidiinikarboksyylihapon valmistamiseksi, joka on hyödyllinen valmistettaessa terapeuttisesti vaikuttavia taksoideja
NO942531L (no)	1994-07-05	Fremgangsmåte for fremstilling av 3-acylöstratriener og acylbenzener