DK0611157T3 - Fremgangsmåde til fremstilling af nukleinsyrer fra en biologisk prøve ved anvendelse af lavt pH og sur protease - Google Patents
Fremgangsmåde til fremstilling af nukleinsyrer fra en biologisk prøve ved anvendelse af lavt pH og sur proteaseInfo
- Publication number
- DK0611157T3 DK0611157T3 DK94300971T DK94300971T DK0611157T3 DK 0611157 T3 DK0611157 T3 DK 0611157T3 DK 94300971 T DK94300971 T DK 94300971T DK 94300971 T DK94300971 T DK 94300971T DK 0611157 T3 DK0611157 T3 DK 0611157T3
- Authority
- DK
- Denmark
- Prior art keywords
- biological sample
- preparation
- low
- nucleic acids
- acid protease
- Prior art date
Links
- 239000012472 biological sample Substances 0.000 title abstract 5
- 150000007523 nucleic acids Chemical class 0.000 title abstract 3
- 102000039446 nucleic acids Human genes 0.000 title abstract 3
- 108020004707 nucleic acids Proteins 0.000 title abstract 3
- 108091005508 Acid proteases Proteins 0.000 title abstract 2
- 101710163270 Nuclease Proteins 0.000 abstract 2
- 108091005804 Peptidases Proteins 0.000 abstract 1
- 239000004365 Protease Substances 0.000 abstract 1
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 abstract 1
- 230000000593 degrading effect Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000000523 sample Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/02—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6478—Aspartic endopeptidases (3.4.23)
- C12N9/6481—Pepsins (3.4.23.1; 3.4.23.2; 3.4.23.3)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/30—Nucleotides
- C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
- C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/81—Packaged device or kit
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/25125—Digestion or removing interfering materials
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gastroenterology & Hepatology (AREA)
- Plant Pathology (AREA)
- Virology (AREA)
- Crystallography & Structural Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/015,729 US5386024A (en) | 1993-02-10 | 1993-02-10 | Method to prepare nucleic acids from a biological sample using low pH and acid protease |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0611157T3 true DK0611157T3 (da) | 2003-05-19 |
Family
ID=21773244
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK94300971T DK0611157T3 (da) | 1993-02-10 | 1994-02-10 | Fremgangsmåde til fremstilling af nukleinsyrer fra en biologisk prøve ved anvendelse af lavt pH og sur protease |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US5386024A (da) |
| EP (1) | EP0611157B1 (da) |
| JP (1) | JP3477205B2 (da) |
| KR (1) | KR960701081A (da) |
| AT (1) | ATE238430T1 (da) |
| AU (2) | AU690895B2 (da) |
| CA (1) | CA2155744C (da) |
| DE (1) | DE69432540T2 (da) |
| DK (1) | DK0611157T3 (da) |
| ES (1) | ES2198411T3 (da) |
| WO (1) | WO1994018238A1 (da) |
Families Citing this family (61)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5545539A (en) * | 1994-10-18 | 1996-08-13 | Genzyme Corporation | Method for nucleotide sequence amplification |
| US5874214A (en) | 1995-04-25 | 1999-02-23 | Irori | Remotely programmable matrices with memories |
| US6416714B1 (en) * | 1995-04-25 | 2002-07-09 | Discovery Partners International, Inc. | Remotely programmable matrices with memories |
| US6331273B1 (en) | 1995-04-25 | 2001-12-18 | Discovery Partners International | Remotely programmable matrices with memories |
| US6017496A (en) | 1995-06-07 | 2000-01-25 | Irori | Matrices with memories and uses thereof |
| US5751629A (en) | 1995-04-25 | 1998-05-12 | Irori | Remotely programmable matrices with memories |
| US6329139B1 (en) | 1995-04-25 | 2001-12-11 | Discovery Partners International | Automated sorting system for matrices with memory |
| US5981235A (en) * | 1996-07-29 | 1999-11-09 | Promega Corporation | Methods for isolating nucleic acids using alkaline protease |
| US7569342B2 (en) | 1997-12-10 | 2009-08-04 | Sierra Molecular Corp. | Removal of molecular assay interferences |
| US6699986B2 (en) * | 1998-08-04 | 2004-03-02 | Ortho-Clinical Diagnostics, Inc. | Electrophoretic separation of nucleic acids from proteins at low ph |
| WO2003064605A2 (en) | 2002-01-28 | 2003-08-07 | Ambion, Inc. | Crude biological derivatives competent for nucleic acid detection |
| DE10237317B4 (de) * | 2002-08-15 | 2010-04-08 | 3M Espe Ag | Enzymhaltige Zusammensetzung, Verfahren zu deren Herstellung und deren Verwendung |
| US7601491B2 (en) * | 2003-02-06 | 2009-10-13 | Becton, Dickinson And Company | Pretreatment method for extraction of nucleic acid from biological samples and kits therefor |
| US20040157219A1 (en) * | 2003-02-06 | 2004-08-12 | Jianrong Lou | Chemical treatment of biological samples for nucleic acid extraction and kits therefor |
| CN100395257C (zh) * | 2003-05-08 | 2008-06-18 | 慈溪市中鼎生物技术有限公司 | 钾离子酸性水溶液和利用这种溶液的dna提取方法和试剂盒 |
| US20050164204A1 (en) * | 2004-01-27 | 2005-07-28 | Reed Thomas D. | Single use lyophilized rnase reagents, and kits and methods for using same |
| EP1716257B8 (en) * | 2004-02-10 | 2012-11-07 | Roche Diagnostics GmbH | New primers and probes for the detection of parvovirus b19 |
| US7794932B2 (en) | 2004-04-16 | 2010-09-14 | Piotr Chomczynski | Reagents and methods for isolation of purified RNA |
| EP1600141B1 (en) * | 2004-05-24 | 2013-04-17 | 3M Deutschland GmbH | Collagenolytic active enzyme containing compositions for the treatment of dental caries |
| US20050277121A1 (en) * | 2004-06-11 | 2005-12-15 | Ambion, Inc. | Crude biological derivatives competent for nucleic acid detection |
| JP5053089B2 (ja) * | 2004-08-03 | 2012-10-17 | ベクトン・ディキンソン・アンド・カンパニー | 化合物の直接単離および多成分サンプルの分別のための磁性材料の使用 |
| JP2008511816A (ja) * | 2004-08-03 | 2008-04-17 | ベクトン・ディキンソン・アンド・カンパニー | サンプルを分別するための磁性材料の使用 |
| US7786086B2 (en) * | 2004-09-08 | 2010-08-31 | Ramot At Tel-Aviv University Ltd. | Peptide nanostructures containing end-capping modified peptides and methods of generating and using the same |
| US20060188892A1 (en) * | 2005-02-18 | 2006-08-24 | Ambion, Inc. | Enzymatic digestion of tissue |
| AU2006214141B2 (en) * | 2005-02-18 | 2010-07-15 | Gen-Probe Incorporated | Sample preparation method incorporating an alkaline shock |
| US8632970B2 (en) | 2005-05-09 | 2014-01-21 | Affymetrix, Inc. | Multiplex capture of nucleic acids |
| EP1880206B1 (en) * | 2005-05-09 | 2012-11-14 | Affymetrix, Inc. | Multiplex capture of nucleic acids |
| ATE502120T1 (de) * | 2005-05-12 | 2011-04-15 | Affymetrix Inc | Multiplex-assays für verzweigtkettige dna |
| EP3042963A1 (en) * | 2005-06-20 | 2016-07-13 | Advanced Cell Diagnostics, Inc. | Methods of detecting nucleic acids in individual cells and of identifying rare cells from large heterogeneous cell populations |
| EP1749892B1 (en) | 2005-08-02 | 2008-03-19 | Roche Diagnostics GmbH | Nucleotide sequence for assessing TSE |
| US20070042408A1 (en) * | 2005-08-02 | 2007-02-22 | Michael Knoll | Nucleotide sequence for assessing transmissible spongiform encephalopathies |
| EP1754464A1 (en) * | 2005-08-17 | 2007-02-21 | 3M Innovative Properties Company | Enzyme comprising dental composition |
| US7569367B2 (en) | 2005-09-07 | 2009-08-04 | Roche Diagnostics Operations, Inc. | Nucleic acid preparation from whole blood for use in diagnosis of transmissible spongiform encephalopathy |
| WO2007044427A2 (en) * | 2005-10-05 | 2007-04-19 | Panomics, Inc. | Detection of nucleic acids from whole blood |
| CA2614069C (en) | 2006-12-11 | 2016-05-03 | F. Hoffmann-La Roche Ag | Nucleic acid isolation using polidocanol and derivatives |
| EP1932913B1 (en) | 2006-12-11 | 2013-01-16 | Roche Diagnostics GmbH | Nucleic acid isolation using polidocanol and derivatives |
| US8535888B2 (en) * | 2006-12-29 | 2013-09-17 | Mayo Foundation For Medical Education And Research | Compositions and methods for detecting methicillin-resistant S. aureus |
| US7964350B1 (en) | 2007-05-18 | 2011-06-21 | Applied Biosystems, Llc | Sample preparation for in situ nucleic acid analysis |
| CA2692186C (en) * | 2007-06-29 | 2019-03-12 | Becton, Dickinson And Company | Methods for extraction and purification of components of biological samples |
| EP2130929B1 (en) | 2008-06-06 | 2013-10-09 | F. Hoffmann-La Roche AG | Internally controlled multiplex detection and quantification of microbial nucleic acids |
| CA2802567C (en) | 2010-07-29 | 2017-12-05 | F. Hoffmann La-Roche Ag | Control nucleic acids for multiple parameters |
| CN107190056A (zh) | 2010-07-29 | 2017-09-22 | 霍夫曼-拉罗奇有限公司 | 微生物核酸的定性和定量检测 |
| JP5972265B2 (ja) | 2010-07-29 | 2016-08-17 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | ジェネリックｐｃｒ |
| CN107058617A (zh) | 2010-07-29 | 2017-08-18 | 霍夫曼-拉罗奇有限公司 | 通用样品制备 |
| EP2426222A1 (en) | 2010-09-07 | 2012-03-07 | F. Hoffmann-La Roche AG | Generic buffer for amplification |
| CA2811333C (en) | 2010-09-16 | 2020-05-12 | Gen-Probe Incorporated | Capture probes immobilizable via l-nucleotide tail |
| ES2562821T3 (es) | 2010-10-21 | 2016-03-08 | Advanced Cell Diagnostics, Inc. | Método ultrasensible para la detección in situ de ácidos nucleicos |
| US9255293B2 (en) | 2010-11-01 | 2016-02-09 | Gen-Probe Incorporated | Integrated capture and amplification of target nucleic acid for sequencing |
| EP2465945A1 (en) | 2010-12-17 | 2012-06-20 | F. Hoffmann-La Roche AG | Generic matrix for control nucleic acids |
| WO2013067069A2 (en) * | 2011-10-31 | 2013-05-10 | Leinweber Barbara | Dual digestion method for high yield nucleic acid recovery |
| AU2013205603B2 (en) | 2012-02-01 | 2016-03-17 | Gen-Probe Incorporated | Asymmetric hairpin target capture oligomers |
| US10017759B2 (en) | 2014-06-26 | 2018-07-10 | Illumina, Inc. | Library preparation of tagged nucleic acid |
| ES2759477T3 (es) | 2015-05-29 | 2020-05-11 | Hoffmann La Roche | Un procedimiento de inactivación de microbios por anhídrido citracónico |
| CN114350752B (zh) | 2015-07-17 | 2025-02-25 | 布鲁克空间生物学公司 | 在横切面组织的用户定义区域中的基因表达的同时定量 |
| EP3913068B1 (en) | 2015-10-12 | 2023-08-02 | Advanced Cell Diagnostics, Inc. | In situ detection of nucleotide variants in high noise samples, and compositions and methods related thereto |
| AU2017361521B2 (en) | 2016-11-21 | 2020-08-27 | Bruker Spatial Biology, Inc. | Chemical compositions and methods of using same |
| KR102893736B1 (ko) | 2018-05-14 | 2025-11-28 | 브루커 스페이셜 바이올로지, 인크. | 화학 조성물 및 이의 사용 방법 |
| EP4653527A3 (en) * | 2021-03-15 | 2026-02-18 | Gen-Probe Incorporated | Use of a composition and method for biological sample processing |
| WO2022209943A1 (ja) | 2021-03-29 | 2022-10-06 | 東レ株式会社 | 生体試料中のマイクロｒｎａの検出方法、中性アミノ酸の塩酸塩の組成物および容器 |
| JP2023018634A (ja) * | 2021-07-27 | 2023-02-08 | 東レ株式会社 | 生体試料中のマイクロｒｎａの検出方法、中性アミノ酸の塩酸塩の組成物および容器 |
| CA3254118A1 (en) | 2022-03-15 | 2023-09-21 | Diagenode S.A. | DETECTION OF THE METHYLATION STATE OF A DNA SAMPLE |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4900677A (en) * | 1986-09-26 | 1990-02-13 | E. I. Du Pont De Nemours And Company | Process for rapid isolation of high molecular weight DNA |
| EP0462221A1 (en) | 1989-03-07 | 1991-12-27 | Syngene, Inc. | In-situ hybridization in suspension for detection or separation of cells |
| US5128247A (en) * | 1989-08-14 | 1992-07-07 | Board Of Regents, The University Of Texas System | Methods for isolation of nucleic acids from eukaryotic and prokaryotic sources |
| US5284940A (en) | 1990-11-14 | 1994-02-08 | Hri Research, Inc. | Preparation for nucleic acid samples |
-
1993
- 1993-02-10 US US08/015,729 patent/US5386024A/en not_active Expired - Lifetime
-
1994
- 1994-02-07 JP JP51831894A patent/JP3477205B2/ja not_active Expired - Fee Related
- 1994-02-07 KR KR1019950703298A patent/KR960701081A/ko not_active Withdrawn
- 1994-02-07 CA CA002155744A patent/CA2155744C/en not_active Expired - Fee Related
- 1994-02-07 WO PCT/US1994/001421 patent/WO1994018238A1/en not_active Ceased
- 1994-02-07 AU AU61359/94A patent/AU690895B2/en not_active Ceased
- 1994-02-10 ES ES94300971T patent/ES2198411T3/es not_active Expired - Lifetime
- 1994-02-10 AT AT94300971T patent/ATE238430T1/de not_active IP Right Cessation
- 1994-02-10 EP EP94300971A patent/EP0611157B1/en not_active Expired - Lifetime
- 1994-02-10 DE DE69432540T patent/DE69432540T2/de not_active Expired - Fee Related
- 1994-02-10 DK DK94300971T patent/DK0611157T3/da active
- 1994-11-30 US US08/347,272 patent/US6610475B1/en not_active Expired - Lifetime
-
1998
- 1998-06-04 AU AU69936/98A patent/AU6993698A/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| DE69432540D1 (de) | 2003-05-28 |
| US5386024A (en) | 1995-01-31 |
| AU6135994A (en) | 1994-08-29 |
| EP0611157A3 (en) | 1994-12-28 |
| KR960701081A (ko) | 1996-02-24 |
| US6610475B1 (en) | 2003-08-26 |
| DE69432540T2 (de) | 2003-11-06 |
| EP0611157A2 (en) | 1994-08-17 |
| JP3477205B2 (ja) | 2003-12-10 |
| JPH08508637A (ja) | 1996-09-17 |
| CA2155744C (en) | 2007-05-15 |
| EP0611157B1 (en) | 2003-04-23 |
| AU6993698A (en) | 1998-07-30 |
| WO1994018238A1 (en) | 1994-08-18 |
| ATE238430T1 (de) | 2003-05-15 |
| ES2198411T3 (es) | 2004-02-01 |
| CA2155744A1 (en) | 1994-08-18 |
| AU690895B2 (en) | 1998-05-07 |
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