DK0611774T3 - Racemiseringsfri fremstilling af amider og peptider i nærværelse af katalytiske mængder af en N-hydroxyforbindelse - Google Patents

Racemiseringsfri fremstilling af amider og peptider i nærværelse af katalytiske mængder af en N-hydroxyforbindelse

Info

Publication number
DK0611774T3
DK0611774T3 DK94101784T DK94101784T DK0611774T3 DK 0611774 T3 DK0611774 T3 DK 0611774T3 DK 94101784 T DK94101784 T DK 94101784T DK 94101784 T DK94101784 T DK 94101784T DK 0611774 T3 DK0611774 T3 DK 0611774T3
Authority
DK
Denmark
Prior art keywords
amides
peptides
hydroxy compound
racemization
catalytic amounts
Prior art date
Application number
DK94101784T
Other languages
English (en)
Inventor
Markus Hohler
Peter Vogt
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=4188840&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0611774(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of DK0611774T3 publication Critical patent/DK0611774T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C07K1/08—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using activating agents
    • C07K1/084—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using activating agents containing nitrogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Indole Compounds (AREA)
DK94101784T 1993-02-19 1994-02-07 Racemiseringsfri fremstilling af amider og peptider i nærværelse af katalytiske mængder af en N-hydroxyforbindelse DK0611774T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH51893 1993-02-19

Publications (1)

Publication Number Publication Date
DK0611774T3 true DK0611774T3 (da) 1999-11-15

Family

ID=4188840

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94101784T DK0611774T3 (da) 1993-02-19 1994-02-07 Racemiseringsfri fremstilling af amider og peptider i nærværelse af katalytiske mængder af en N-hydroxyforbindelse

Country Status (8)

Country Link
US (2) US5536816A (da)
EP (1) EP0611774B1 (da)
JP (1) JP2524685B2 (da)
CN (1) CN1035873C (da)
AT (1) ATE180491T1 (da)
DE (1) DE59408292D1 (da)
DK (1) DK0611774T3 (da)
ES (1) ES2133428T3 (da)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0611774B1 (de) * 1993-02-19 1999-05-26 F. Hoffmann-La Roche Ag Racemisierungsfreie Herstellung von Amiden und Peptiden in Gegenwart katalytischer Mengen einer N-Hydroxy-Verbindung
GB9424842D0 (en) * 1994-12-09 1995-02-08 British Tech Group Pharmaceutical compositions
EP0823424A1 (de) * 1996-08-09 1998-02-11 F. Hoffmann-La Roche Ag Verfahren zur Herstellung von Chinargin
US5914404A (en) * 1996-08-09 1999-06-22 Hoffmann-La Roche Inc. Process for the preparation of quinargine
EP0847994B1 (de) 1996-12-11 2003-04-09 F. Hoffmann-La Roche Ag Verfahren zur Herstellung gemischter Anhydride
WO1999065931A1 (en) * 1998-06-17 1999-12-23 Magainin Pharmaceuticals, Inc. Non-enzymatic chemical amidation process
JP4949557B2 (ja) * 1999-03-17 2012-06-13 ノヴォ ノルディスク アー／エス ペプチドのアシル化方法及び新規アシル化剤
US6719080B1 (en) 2000-01-10 2004-04-13 The United States Of America As Represented By The Administrator Of The Environmental Protection Agency Hydraulic hybrid vehicle
AU2002238965B8 (en) * 2001-03-19 2007-05-17 Fujimori Kogyo Co., Ltd. Thrombin derivatives and process for producing the same, anhydrothrombin derivatives and process for producing the same, platelet agglutination-inducing compositions, method of inducing platelet agglutination, clinical test reagents, clinical test method, thrombosis inhibitors, adsorbent and process for producing the same
US7423166B2 (en) * 2001-12-13 2008-09-09 Advanced Technology Materials, Inc. Stabilized cyclosiloxanes for use as CVD precursors for low-dielectric constant thin films
US7273921B2 (en) 2002-09-25 2007-09-25 Novo Nordisk A/S Method for producing acylated peptides
US20040077703A1 (en) * 2002-10-02 2004-04-22 Soll Mark D. Nodulisporic acid derivative spot-on formulations for combating parasites
CN103113177B (zh) * 2013-02-06 2015-02-04 济南志合医药科技有限公司 一种酰胺的制备方法
WO2014147129A1 (en) 2013-03-21 2014-09-25 Sanofi-Aventis Deutschland Gmbh Synthesis of cyclic imide containing peptide products
CN105189465B (zh) 2013-03-21 2019-02-26 赛诺菲-安万特德国有限公司 合成含有乙内酰脲的肽产物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2202613C3 (de) * 1972-01-20 1974-06-20 Farbwerke Hoechst Ag, Vormals Meister Lucius & Bruening, 6000 Frankfurt Verfahren zur Herstellung von Peptiden
US5580981A (en) * 1992-09-28 1996-12-03 Research Corporation Technologies, Inc. Azahydroxybenzotriazoles and derivatives thereof for peptide coupling reactions
EP0611774B1 (de) * 1993-02-19 1999-05-26 F. Hoffmann-La Roche Ag Racemisierungsfreie Herstellung von Amiden und Peptiden in Gegenwart katalytischer Mengen einer N-Hydroxy-Verbindung

Also Published As

Publication number Publication date
ATE180491T1 (de) 1999-06-15
JPH06256225A (ja) 1994-09-13
EP0611774B1 (de) 1999-05-26
JP2524685B2 (ja) 1996-08-14
DE59408292D1 (de) 1999-07-01
EP0611774A1 (de) 1994-08-24
CN1111237A (zh) 1995-11-08
CN1035873C (zh) 1997-09-17
US5536816A (en) 1996-07-16
US5750649A (en) 1998-05-12
ES2133428T3 (es) 1999-09-16

Similar Documents

Publication Publication Date Title
DK0611774T3 (da) Racemiseringsfri fremstilling af amider og peptider i nærværelse af katalytiske mængder af en N-hydroxyforbindelse
DE69324552D1 (de) N'-substituierte-N,N'Diacylhydrazin-Insektizide
DK0422938T3 (da) Fibrinogenreceptorantagonister
DK0422937T3 (da) Fibrinogenreceptorantagonister
NO930193D0 (no) Biarylsubstituerte 4-aminosmoersyreamider
GR3004018T3 (da)
DK0623589T3 (da) Koblingsreagens og fremgangsmåde til kobling af aminer med carboxylsyrer
DE69132435D1 (de) Inhibitoren retroviraler Proteasen
EP0742209A3 (en) Process for the preparation of an optically active quinoline demevalonolacton and process for the preparation of a salt of an optically active quinoline demevalolon
DK158345C (da) Fremgangsmaade til fremstilling af carboxylsyreamider og peptider
DE59104984D1 (de) Verfahren zur N-Alkylierung von Harnstoffen.
DK0510625T3 (da) Fremgangsmåde til fremstilling af lysstabilisatorer med hindrede aminogrupper
TW228520B (da)
DE59301060D1 (de) Substituierte Aminosäureamide.
DK0640608T3 (da) Mellemprodukter til syntese af cephalosporiner
ZA948631B (en) 5-arylisoxazol-4-yl-substituted 2-amino carboxylic acid compounds
NO178231C (no) Umettede polyesterharpiksblandinger og anvendelse av disse
IL145723A0 (en) Process for producing an amide compound
DK659188A (da) Fremgangsmaade til fremstiling af isothiazoloner
DE3164897D1 (en) Process for preparing 1-amino-3-aryloxy-2-propanols and 1-amino-2-aryl-2-ethanols
ATE161263T1 (de) 2,4-diamino-1,3,5-triazinyl-6- phosphonsäurederivate
DK0638554T3 (da) Fremgangsmåde til fremstilling af et N-phenyl-N-(4-piperidinyl)amidderivat
SE8004373L (sv) Dragbandstakstol
ATE201688T1 (de) Verfahren zur herstellung von 3-substituierten cephem-derivaten
SK173U (sk) Spájkovacia slučka pre elektrickú transformátorovú spájkovačku

Legal Events

Date Code Title Description
AHB Application shelved due to non-payment