DK0612242T3 - Anvendelse af ren S(+)-isomer af fluoxetin til fremstilling af et medikament mod migræne - Google Patents
Anvendelse af ren S(+)-isomer af fluoxetin til fremstilling af et medikament mod migræneInfo
- Publication number
- DK0612242T3 DK0612242T3 DK92906545T DK92906545T DK0612242T3 DK 0612242 T3 DK0612242 T3 DK 0612242T3 DK 92906545 T DK92906545 T DK 92906545T DK 92906545 T DK92906545 T DK 92906545T DK 0612242 T3 DK0612242 T3 DK 0612242T3
- Authority
- DK
- Denmark
- Prior art keywords
- fluoxetine
- pure
- isomer
- compositions
- methods
- Prior art date
Links
- 229960002464 fluoxetine Drugs 0.000 title abstract 4
- RTHCYVBBDHJXIQ-MRXNPFEDSA-N (R)-fluoxetine Chemical compound O([C@H](CCNC)C=1C=CC=CC=1)C1=CC=C(C(F)(F)F)C=C1 RTHCYVBBDHJXIQ-MRXNPFEDSA-N 0.000 title abstract 3
- 208000019695 Migraine disease Diseases 0.000 title abstract 2
- 229940079593 drug Drugs 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 206010027599 migraine Diseases 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 3
- 208000002193 Pain Diseases 0.000 abstract 2
- 208000000094 Chronic Pain Diseases 0.000 abstract 1
- 206010027603 Migraine headaches Diseases 0.000 abstract 1
- 208000021384 Obsessive-Compulsive disease Diseases 0.000 abstract 1
- 230000002411 adverse Effects 0.000 abstract 1
- 230000001430 anti-depressive effect Effects 0.000 abstract 1
- 239000000935 antidepressant agent Substances 0.000 abstract 1
- 229940005513 antidepressants Drugs 0.000 abstract 1
- 239000002830 appetite depressant Substances 0.000 abstract 1
- 230000008517 inhibition of serotonin uptake Effects 0.000 abstract 1
- 210000002569 neuron Anatomy 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
- 230000004800 psychological effect Effects 0.000 abstract 1
- 230000000862 serotonergic effect Effects 0.000 abstract 1
- 231100000331 toxic Toxicity 0.000 abstract 1
- 230000002110 toxicologic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Diabetes (AREA)
- Hospice & Palliative Care (AREA)
- Epidemiology (AREA)
- Child & Adolescent Psychology (AREA)
- Anesthesiology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Addiction (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US79303691A | 1991-11-15 | 1991-11-15 | |
| PCT/US1992/000888 WO1993009769A1 (en) | 1991-11-15 | 1992-02-05 | Methods and compositions utilizing pure s(+) isomer fluoxetine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0612242T3 true DK0612242T3 (da) | 2003-10-20 |
Family
ID=25158891
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK92906545T DK0612242T3 (da) | 1991-11-15 | 1992-02-05 | Anvendelse af ren S(+)-isomer af fluoxetin til fremstilling af et medikament mod migræne |
Country Status (9)
| Country | Link |
|---|---|
| EP (2) | EP0612242B1 (de) |
| JP (2) | JPH07500812A (de) |
| AT (1) | ATE244563T1 (de) |
| AU (2) | AU1373692A (de) |
| CA (1) | CA2123704C (de) |
| DE (1) | DE69233124T2 (de) |
| DK (1) | DK0612242T3 (de) |
| ES (1) | ES2197144T3 (de) |
| WO (1) | WO1993009769A1 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT639374E (pt) * | 1993-06-28 | 2002-07-31 | American Home Prod | Novos tratamentos utilizado derivados fenetilo |
| ES2082723B1 (es) * | 1994-07-20 | 1996-10-01 | Lilly Sa | Formulacion farmaceutica de fluoxetina en forma dispersable. |
| US6548084B2 (en) | 1995-07-20 | 2003-04-15 | Smithkline Beecham Plc | Controlled release compositions |
| ES2103682B1 (es) * | 1995-09-20 | 1998-04-01 | Lilly Sa | Composicion farmaceutica oral de fluoxetina, solida y con caracteristicas organolepticas mejoradas. |
| AR021155A1 (es) | 1999-07-08 | 2002-06-12 | Lundbeck & Co As H | Tratamiento de desordenes neuroticos |
| US6846957B2 (en) | 2002-11-22 | 2005-01-25 | Board Of Regents, The University Of Texas System | Synthesis of 3-aminomethyl-1-propanol, a fluoxetine precursor |
| CN111643475A (zh) * | 2020-07-20 | 2020-09-11 | 华益药业科技(安徽)有限公司 | 一种氟西汀胶囊生产工艺 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GR75395B (de) * | 1980-11-14 | 1984-07-13 | Lilly Co Eli |
-
1992
- 1992-02-05 AT AT92906545T patent/ATE244563T1/de not_active IP Right Cessation
- 1992-02-05 AU AU13736/92A patent/AU1373692A/en not_active Abandoned
- 1992-02-05 DK DK92906545T patent/DK0612242T3/da active
- 1992-02-05 DE DE69233124T patent/DE69233124T2/de not_active Expired - Fee Related
- 1992-02-05 EP EP92906545A patent/EP0612242B1/de not_active Expired - Lifetime
- 1992-02-05 EP EP02003532A patent/EP1208838A3/de not_active Withdrawn
- 1992-02-05 JP JP4506297A patent/JPH07500812A/ja active Pending
- 1992-02-05 ES ES92906545T patent/ES2197144T3/es not_active Expired - Lifetime
- 1992-02-05 CA CA002123704A patent/CA2123704C/en not_active Expired - Fee Related
- 1992-02-05 WO PCT/US1992/000888 patent/WO1993009769A1/en not_active Ceased
-
1997
- 1997-04-17 AU AU18917/97A patent/AU1891797A/en not_active Abandoned
-
2003
- 2003-08-28 JP JP2003304079A patent/JP2004002474A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU1891797A (en) | 1997-06-19 |
| JPH07500812A (ja) | 1995-01-26 |
| WO1993009769A1 (en) | 1993-05-27 |
| DE69233124D1 (de) | 2003-08-14 |
| ES2197144T3 (es) | 2004-01-01 |
| JP2004002474A (ja) | 2004-01-08 |
| AU1373692A (en) | 1993-06-15 |
| EP0612242A1 (de) | 1994-08-31 |
| EP0612242A4 (en) | 1997-01-15 |
| CA2123704C (en) | 2003-01-21 |
| CA2123704A1 (en) | 1993-05-27 |
| EP1208838A3 (de) | 2003-07-09 |
| DE69233124T2 (de) | 2004-02-19 |
| ATE244563T1 (de) | 2003-07-15 |
| EP1208838A2 (de) | 2002-05-29 |
| EP0612242B1 (de) | 2003-07-09 |
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