DK0612716T3 - Fremgangsmåde til fremstilling af en optisk ren aminoalkohol - Google Patents

Fremgangsmåde til fremstilling af en optisk ren aminoalkohol

Info

Publication number: DK0612716T3
Authority: DK; Denmark
Prior art keywords: preparation; dichlorophenyl; amino alcohol; optically pure; pure amino
Prior art date: 1993-02-26

Application number

DK94400409.2T

Other languages

English (en)

Inventor

Marcel Descamps

Joel Radisson

Original Assignee

Sanofi Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-02-26

Filing date

1994-02-25

Publication date

1996-08-19

1994-02-25 Application filed by Sanofi Sa filed Critical Sanofi Sa

1996-08-19 Application granted granted Critical

1996-08-19 Publication of DK0612716T3 publication Critical patent/DK0612716T3/da

Links

238000000034 method Methods 0.000 title abstract 2
150000001414 amino alcohols Chemical class 0.000 title 1
UZSGNCYEUGJVLO-UHFFFAOYSA-N 3-cyano-3-(3,4-dichlorophenyl)propanoic acid Chemical compound OC(=O)CC(C#N)C1=CC=C(Cl)C(Cl)=C1 UZSGNCYEUGJVLO-UHFFFAOYSA-N 0.000 abstract 3
QWZNCAFWRZZJMA-UHFFFAOYSA-N 2-(3,4-dichlorophenyl)acetonitrile Chemical compound ClC1=CC=C(CC#N)C=C1Cl QWZNCAFWRZZJMA-UHFFFAOYSA-N 0.000 abstract 2
UORVGPXVDQYIDP-UHFFFAOYSA-N borane Chemical compound B UORVGPXVDQYIDP-UHFFFAOYSA-N 0.000 abstract 2
MBBZMMPHUWSWHV-DBRKOABJSA-N (2r,3r,4r,5r)-6-(methylamino)hexane-1,2,3,4,5-pentol Chemical class CNC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO MBBZMMPHUWSWHV-DBRKOABJSA-N 0.000 abstract 1
LGIGCDLFWQIHLQ-UHFFFAOYSA-N 4-amino-3-(3,4-dichlorophenyl)butan-1-ol Chemical compound OCCC(CN)C1=CC=C(Cl)C(Cl)=C1 LGIGCDLFWQIHLQ-UHFFFAOYSA-N 0.000 abstract 1
MBBZMMPHUWSWHV-BDVNFPICSA-N N-methylglucamine Chemical compound CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO MBBZMMPHUWSWHV-BDVNFPICSA-N 0.000 abstract 1
229910052783 alkali metal Inorganic materials 0.000 abstract 1
150000001340 alkali metals Chemical class 0.000 abstract 1
229910000085 borane Inorganic materials 0.000 abstract 1
238000006243 chemical reaction Methods 0.000 abstract 1
230000007062 hydrolysis Effects 0.000 abstract 1
238000006460 hydrolysis reaction Methods 0.000 abstract 1
230000009466 transformation Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C215/22—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
- C07C215/28—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
- C07C255/32—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring
- C07C255/41—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by carboxyl groups, other than cyano groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DK94400409.2T 1993-02-26 1994-02-25 Fremgangsmåde til fremstilling af en optisk ren aminoalkohol DK0612716T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR9302262A FR2701946B1 (fr)	1993-02-26	1993-02-26	Procédé pour la préparation d'un aminoalcool optiquement pur.

Publications (1)

Publication Number	Publication Date
DK0612716T3 true DK0612716T3 (da)	1996-08-19

Family

ID=9444482

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK94400409.2T DK0612716T3 (da)	1993-02-26	1994-02-25	Fremgangsmåde til fremstilling af en optisk ren aminoalkohol

Country Status (12)

Country	Link
EP (1)	EP0612716B1 (da)
JP (1)	JP2546624B2 (da)
CN (2)	CN1053655C (da)
AT (1)	ATE137736T1 (da)
CA (1)	CA2116464C (da)
DE (1)	DE69400170T2 (da)
DK (1)	DK0612716T3 (da)
ES (1)	ES2089889T3 (da)
FR (1)	FR2701946B1 (da)
GR (1)	GR3020346T3 (da)
HU (1)	HU213260B (da)
TW (1)	TW240216B (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5512680A (en) *	1993-02-26	1996-04-30	Sanofi	Process for the preparation of an optically pure aminoalcohol
WO2007136323A1 (en) *	2006-05-18	2007-11-29	Albireo Ab	A novel process suitable for large-scale production of phenyl propan derivatives of formula i
DE202008001786U1 (de)	2007-03-12	2008-12-24	Inventio Ag	Aufzugsanlage, Tragmittel für eine Aufzugsanlage und Vorrichtung zur Herstellung eines Tragmittels
CZ301920B6 (cs) *	2009-06-16	2010-07-28	Zentiva, K. S.	Zpusob výroby (S)-4-methylamino-3-(3,4-dichlorfenyl)butan-1-olu
WO2017009753A1 (en) *	2015-07-13	2017-01-19	Piramal Enterprises Limited	An improved process for the preparation of baclofen and its intermediate
CN107445864B (zh) *	2017-08-09	2020-01-17	无锡殷达尼龙有限公司	一种纯化长碳链氰基酸产物的方法
CN107311911B (zh) *	2017-08-21	2020-09-08	钟桂发	一种尼拉帕尼的手性中间体的制备方法
CN118324601B (zh) *	2024-06-13	2024-09-03	山东理工大学	基于d-葡萄糖接枝型消旋助剂的氨基酸消旋方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IE903957A1 (en) *	1989-11-06	1991-05-08	Sanofi Sa	Aromatic amine compounds, their method of preparation and¹pharmaceutical compositions in which they are present

1993
- 1993-02-26 FR FR9302262A patent/FR2701946B1/fr not_active Expired - Fee Related
1994
- 1994-02-19 TW TW083101427A patent/TW240216B/zh not_active IP Right Cessation
- 1994-02-25 AT AT94400409T patent/ATE137736T1/de active
- 1994-02-25 HU HU9400562A patent/HU213260B/hu not_active IP Right Cessation
- 1994-02-25 DE DE69400170T patent/DE69400170T2/de not_active Expired - Lifetime
- 1994-02-25 ES ES94400409T patent/ES2089889T3/es not_active Expired - Lifetime
- 1994-02-25 DK DK94400409.2T patent/DK0612716T3/da active
- 1994-02-25 CA CA002116464A patent/CA2116464C/en not_active Expired - Fee Related
- 1994-02-25 EP EP94400409A patent/EP0612716B1/fr not_active Expired - Lifetime
- 1994-02-26 CN CN94101933.0A patent/CN1053655C/zh not_active Expired - Fee Related
- 1994-02-28 JP JP6030491A patent/JP2546624B2/ja not_active Expired - Fee Related
1996
- 1996-06-27 GR GR960401715T patent/GR3020346T3/el unknown
1999
- 1999-06-30 CN CN99108919A patent/CN1122660C/zh not_active Expired - Fee Related

Also Published As

Publication number	Publication date
ATE137736T1 (de)	1996-05-15
CN1100410A (zh)	1995-03-22
ES2089889T3 (es)	1996-10-01
CN1242358A (zh)	2000-01-26
DE69400170D1 (de)	1996-06-13
FR2701946A1 (fr)	1994-09-02
HU9400562D0 (en)	1994-05-30
EP0612716A1 (fr)	1994-08-31
FR2701946B1 (fr)	1995-05-24
JP2546624B2 (ja)	1996-10-23
HUT66401A (en)	1994-11-28
TW240216B (da)	1995-02-11
CA2116464C (en)	1997-10-21
HU213260B (en)	1997-04-28
DE69400170T2 (de)	1996-10-02
CN1053655C (zh)	2000-06-21
CN1122660C (zh)	2003-10-01
EP0612716B1 (fr)	1996-05-08
CA2116464A1 (en)	1994-08-27
JPH06340595A (ja)	1994-12-13
GR3020346T3 (en)	1996-09-30

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