DK0625985T3 - Fremgangsmåde og ringåbnede purinforbindelser til mærkning af polynukleotider - Google Patents
Fremgangsmåde og ringåbnede purinforbindelser til mærkning af polynukleotiderInfo
- Publication number
- DK0625985T3 DK0625985T3 DK93900665.6T DK93900665T DK0625985T3 DK 0625985 T3 DK0625985 T3 DK 0625985T3 DK 93900665 T DK93900665 T DK 93900665T DK 0625985 T3 DK0625985 T3 DK 0625985T3
- Authority
- DK
- Denmark
- Prior art keywords
- ring
- opened
- polynucleotides
- provides
- purine compounds
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 102000040430 polynucleotide Human genes 0.000 title abstract 3
- 108091033319 polynucleotide Proteins 0.000 title abstract 3
- 239000002157 polynucleotide Substances 0.000 title abstract 3
- 238000002372 labelling Methods 0.000 title abstract 2
- 125000000561 purinyl group Chemical class N1=C(N=C2N=CNC2=C1)* 0.000 title 1
- 150000003212 purines Chemical class 0.000 abstract 4
- RAXXELZNTBOGNW-UHFFFAOYSA-N imidazole Natural products C1=CNC=N1 RAXXELZNTBOGNW-UHFFFAOYSA-N 0.000 abstract 3
- 229940083251 peripheral vasodilators purine derivative Drugs 0.000 abstract 2
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 230000000903 blocking effect Effects 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 238000001212 derivatisation Methods 0.000 abstract 1
- 230000002255 enzymatic effect Effects 0.000 abstract 1
- 125000005647 linker group Chemical group 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/12—Acyclic radicals, not substituted by cyclic structures attached to a nitrogen atom of the saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/975—Kit
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US80281591A | 1991-12-06 | 1991-12-06 | |
| PCT/US1992/010190 WO1993011146A1 (en) | 1991-12-06 | 1992-12-03 | Method and ring-opened purine compounds for labeling polynucleotides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0625985T3 true DK0625985T3 (da) | 1997-12-29 |
Family
ID=25184785
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK93900665.6T DK0625985T3 (da) | 1991-12-06 | 1992-12-03 | Fremgangsmåde og ringåbnede purinforbindelser til mærkning af polynukleotider |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US5593829A (da) |
| EP (1) | EP0625985B1 (da) |
| AT (1) | ATE154360T1 (da) |
| AU (1) | AU671970B2 (da) |
| DE (1) | DE69220383T2 (da) |
| DK (1) | DK0625985T3 (da) |
| ES (1) | ES2106317T3 (da) |
| GR (1) | GR3024649T3 (da) |
| NZ (1) | NZ246228A (da) |
| WO (1) | WO1993011146A1 (da) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0625985B1 (en) * | 1991-12-06 | 1997-06-11 | University Of Miami | Method and ring-opened purine compounds for labeling polynucleotides |
| US5989873A (en) * | 1996-09-24 | 1999-11-23 | Vinayagamoorthy; Thuraiayah | Method of detecting gene expression and/or of preventing such expression in cells |
| US20050070005A1 (en) * | 1997-06-16 | 2005-03-31 | Martin Keller | High throughput or capillary-based screening for a bioactivity or biomolecule |
| EP1023463A4 (en) * | 1997-10-09 | 2003-01-02 | Transgenomic Inc | MODIFICATION OF DOUBLE-STRANDED DNA TO IMPROVE CHROMATOGRAPHIC SEPARATIONS OF MATCHED ION POLYNUCLEOTIDES |
| US6566059B1 (en) * | 1998-10-01 | 2003-05-20 | Variagenics, Inc. | Method for analyzing polynucleotides |
| US6506567B2 (en) * | 2000-01-31 | 2003-01-14 | Fuji Photo Film Co., Ltd. | Water-soluble flourescent intercalator compound |
| US20070259397A1 (en) * | 2004-07-28 | 2007-11-08 | Danisco A/S | Enzymes |
| CN106982161B (zh) | 2012-11-22 | 2020-07-24 | 华为技术有限公司 | 环网保护中标签保持和删除的方法及设备 |
| WO2024044232A1 (en) * | 2022-08-23 | 2024-02-29 | Emory University | Compositions and methods for selective labeling of n-alkylated imidazole containing compounds and peptides |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1219824A (en) * | 1981-04-17 | 1987-03-31 | David C. Ward | Modified nucleotides and methods of preparing and using same |
| EP0135587B2 (en) * | 1983-02-22 | 2002-12-18 | Syngene, Inc. | Defined sequence single strand oligonucleotides incorporating reporter groups, process for the chemical synthesis thereof, and nucleosides useful in such synthesis |
| EP0144176B1 (en) * | 1983-11-18 | 1991-12-11 | FUJIREBIO KABUSHIKI KAISHA also trading as FUJIREBIO INC. | Method of measuring a biological ligand |
| US4849505A (en) * | 1984-01-30 | 1989-07-18 | Enzo Biochem, Inc. | Detectable molecules, method of preparation and use |
| US4705886A (en) * | 1984-03-21 | 1987-11-10 | Cetus Corporation | Precursor to nucleic acid probe |
| EP0625985B1 (en) * | 1991-12-06 | 1997-06-11 | University Of Miami | Method and ring-opened purine compounds for labeling polynucleotides |
-
1992
- 1992-12-03 EP EP93900665A patent/EP0625985B1/en not_active Expired - Lifetime
- 1992-12-03 DK DK93900665.6T patent/DK0625985T3/da active
- 1992-12-03 NZ NZ246228A patent/NZ246228A/en unknown
- 1992-12-03 WO PCT/US1992/010190 patent/WO1993011146A1/en not_active Ceased
- 1992-12-03 ES ES93900665T patent/ES2106317T3/es not_active Expired - Lifetime
- 1992-12-03 AU AU32257/93A patent/AU671970B2/en not_active Ceased
- 1992-12-03 AT AT93900665T patent/ATE154360T1/de not_active IP Right Cessation
- 1992-12-03 DE DE69220383T patent/DE69220383T2/de not_active Expired - Fee Related
-
1994
- 1994-05-03 US US08/241,385 patent/US5593829A/en not_active Expired - Fee Related
-
1995
- 1995-06-06 US US08/469,925 patent/US5656742A/en not_active Expired - Fee Related
-
1997
- 1997-09-09 GR GR970402287T patent/GR3024649T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU3225793A (en) | 1993-06-28 |
| US5656742A (en) | 1997-08-12 |
| DE69220383T2 (de) | 1998-01-29 |
| ES2106317T3 (es) | 1997-11-01 |
| AU671970B2 (en) | 1996-09-19 |
| ATE154360T1 (de) | 1997-06-15 |
| US5593829A (en) | 1997-01-14 |
| EP0625985B1 (en) | 1997-06-11 |
| DE69220383D1 (de) | 1997-07-17 |
| WO1993011146A1 (en) | 1993-06-10 |
| GR3024649T3 (en) | 1997-12-31 |
| EP0625985A1 (en) | 1994-11-30 |
| NZ246228A (en) | 1995-12-21 |
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