DK0627006T3 - Hybrid-DNA, der koder for en underenhed af et bakterietoxin med et hæmolysin. - Google Patents

Hybrid-DNA, der koder for en underenhed af et bakterietoxin med et hæmolysin.

Info

Publication number
DK0627006T3
DK0627006T3 DK93905242.9T DK93905242T DK0627006T3 DK 0627006 T3 DK0627006 T3 DK 0627006T3 DK 93905242 T DK93905242 T DK 93905242T DK 0627006 T3 DK0627006 T3 DK 0627006T3
Authority
DK
Denmark
Prior art keywords
hemolysin
subunit
hybrid dna
bacterial toxin
dna encoding
Prior art date
Application number
DK93905242.9T
Other languages
English (en)
Inventor
J Wehland
Himanshu Brahmbhatt
Guo-Fu Su
Kenneth N Timmis
Original Assignee
F Ges
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Ges filed Critical F Ges
Application granted granted Critical
Publication of DK0627006T3 publication Critical patent/DK0627006T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/245—Escherichia (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/25—Shigella (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/55—Fusion polypeptide containing a fusion with a toxin, e.g. diphteria toxin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/61—Fusion polypeptide containing an enzyme fusion for detection (lacZ, luciferase)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
DK93905242.9T 1992-02-17 1993-02-12 Hybrid-DNA, der koder for en underenhed af et bakterietoxin med et hæmolysin. DK0627006T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4204737 1992-02-17
DE4219696A DE4219696A1 (de) 1992-02-17 1992-06-16 Hybrid-dna, plasmide, oligohybridpeptid und impfstoff

Publications (1)

Publication Number Publication Date
DK0627006T3 true DK0627006T3 (da) 1997-11-03

Family

ID=25911935

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93905242.9T DK0627006T3 (da) 1992-02-17 1993-02-12 Hybrid-DNA, der koder for en underenhed af et bakterietoxin med et hæmolysin.

Country Status (8)

Country Link
EP (1) EP0627006B1 (da)
JP (1) JPH07505052A (da)
AT (1) ATE152483T1 (da)
AU (1) AU672388B2 (da)
DE (2) DE4219696A1 (da)
DK (1) DK0627006T3 (da)
ES (1) ES2104130T3 (da)
WO (1) WO1993016186A1 (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2766193B1 (fr) * 1997-07-18 2001-09-14 Inst Curie Polypeptide chimerique comprenant le fragment b de la toxine shiga et des peptides d'interet therapeutique
EP1078007B1 (en) 1998-05-15 2005-11-23 Institut Curie Verotoxin b subunit for immunization
US6264087B1 (en) 1999-07-12 2001-07-24 Powermed, Inc. Expanding parallel jaw device for use with an electromechanical driver device
EP1057895A1 (de) * 1999-06-04 2000-12-06 Lohmann Animal Health GmbH & Co. KG Fusionsprotein das das Fragment B des Shigatoxins enthält, dieses enthaltende (Impf-)Stoffzusammensetzung und Verfahren zu dessen Herstellung

Also Published As

Publication number Publication date
AU3628293A (en) 1993-09-03
DE4219696A1 (de) 1993-08-19
AU672388B2 (en) 1996-10-03
WO1993016186A1 (de) 1993-08-19
ES2104130T3 (es) 1997-10-01
ATE152483T1 (de) 1997-05-15
EP0627006A1 (de) 1994-12-07
JPH07505052A (ja) 1995-06-08
EP0627006B1 (de) 1997-05-02
DE59306342D1 (de) 1997-06-05

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