DK0627431T3 - Fremgangsmåde til fremstilling af krystallinsk loracarbef-monohydrat - Google Patents

Fremgangsmåde til fremstilling af krystallinsk loracarbef-monohydrat

Info

Publication number: DK0627431T3
Authority: DK; Denmark
Prior art keywords: preparation; loracarbef monohydrate; crystalline; crystalline loracarbef; monohydrate
Prior art date: 1993-06-04

Application number

DK94303946.1T

Other languages

Danish (da)

English (en)

Inventor

Robert Louis Nist

Marvin Emanuel Wildfeuer

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-06-04

Filing date

1994-06-01

Publication date

1997-08-25

1994-06-01 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

1997-08-25 Application granted granted Critical

1997-08-25 Publication of DK0627431T3 publication Critical patent/DK0627431T3/da

Links

GPYKKBAAPVOCIW-HSASPSRMSA-N (6r,7s)-7-[[(2r)-2-amino-2-phenylacetyl]amino]-3-chloro-8-oxo-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;hydrate Chemical compound O.C1([C@H](C(=O)N[C@@H]2C(N3C(=C(Cl)CC[C@@H]32)C(O)=O)=O)N)=CC=CC=C1 GPYKKBAAPVOCIW-HSASPSRMSA-N 0.000 title abstract 2
150000004682 monohydrates Chemical group 0.000 abstract 3
229960001977 loracarbef Drugs 0.000 abstract 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
- C07D205/085—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a nitrogen atom directly attached in position 3
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Cephalosporin Compounds (AREA)

DK94303946.1T 1993-06-04 1994-06-01 Fremgangsmåde til fremstilling af krystallinsk loracarbef-monohydrat DK0627431T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US08/071,552 US5352782A (en)	1993-06-04	1993-06-04	Process for preparing crystalline β-lactam monohydrate

Publications (1)

Publication Number	Publication Date
DK0627431T3 true DK0627431T3 (da)	1997-08-25

Family

ID=22102062

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK94303946.1T DK0627431T3 (da)	1993-06-04	1994-06-01	Fremgangsmåde til fremstilling af krystallinsk loracarbef-monohydrat

Country Status (29)

Country	Link
US (1)	US5352782A (fr)
EP (1)	EP0627431B1 (fr)
JP (1)	JPH06345761A (fr)
KR (1)	KR950000702A (fr)
CN (1)	CN1045296C (fr)
AT (1)	ATE156129T1 (fr)
AU (1)	AU682503B2 (fr)
BR (1)	BR9402150A (fr)
CA (1)	CA2125000A1 (fr)
CO (1)	CO4230099A1 (fr)
CZ (1)	CZ284225B6 (fr)
DE (1)	DE69404560T2 (fr)
DK (1)	DK0627431T3 (fr)
ES (1)	ES2105524T3 (fr)
FI (1)	FI942632A7 (fr)
GR (1)	GR3024989T3 (fr)
HU (1)	HU217067B (fr)
IL (1)	IL109870A (fr)
MY (1)	MY110725A (fr)
NO (1)	NO307052B1 (fr)
NZ (1)	NZ260652A (fr)
PE (1)	PE13295A1 (fr)
PH (1)	PH30184A (fr)
PL (1)	PL174535B1 (fr)
RU (1)	RU2130456C1 (fr)
TW (1)	TW449596B (fr)
UA (1)	UA34440C2 (fr)
YU (1)	YU33494A (fr)
ZA (1)	ZA943826B (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5399686A (en) *	1993-06-04	1995-03-21	Eli Lilly And Company	Loracarbef isopropanolate and a process for converting loracarbef isopropanolate to loracarbef monohydrate
US5550231A (en) *	1993-06-15	1996-08-27	Eli Lilly And Company	Loracarbef hydrochloride C1-C3 alcohol solvates and uses thereof
US5580977A (en) *	1995-03-01	1996-12-03	Eli Lilly And Company	Process for preparing loracarbef monohydrate
EP1565462A1 (fr) *	2002-11-21	2005-08-24	Ranbaxy Laboratories, Ltd.	Solvates de monohydrate de loracarbef

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3502663A (en) *	1969-04-21	1970-03-24	Lilly Co Eli	Crystalline cephalosporin,method for its manufacture
US3531481A (en) *	1969-04-21	1970-09-29	Lilly Co Eli	Method for manufacture of crystalline cephalosporin
CA1334970C (fr) *	1987-10-06	1995-03-28	Carol Elaine Pasini	Hydrate de .beta.-lactame cristallin
US4977257A (en) *	1988-11-14	1990-12-11	Eli Lilly And Company	DMF solvates of a β-lactam antibiotic
CA2002596A1 (fr) *	1988-11-14	1990-05-14	Thomas M. Eckrich	Hydrates de beta-lactam antibiotiques
CA2002597C (fr) *	1988-11-14	1999-03-23	Thomas M. Eckrich	Solvates de beta-lactam antibiotiques
CA2034592C (fr) *	1990-01-26	2001-06-05	Ralph R. Pfeiffer	Chlorhydrate crystallin d'un nouvel antibiotique de type beta-lactame et procede pour sa fabrication

1993
- 1993-06-04 US US08/071,552 patent/US5352782A/en not_active Expired - Lifetime
1994
- 1994-06-01 DK DK94303946.1T patent/DK0627431T3/da active
- 1994-06-01 AT AT94303946T patent/ATE156129T1/de not_active IP Right Cessation
- 1994-06-01 ZA ZA943826A patent/ZA943826B/xx unknown
- 1994-06-01 EP EP94303946A patent/EP0627431B1/fr not_active Expired - Lifetime
- 1994-06-01 PL PL94303677A patent/PL174535B1/pl unknown
- 1994-06-01 ES ES94303946T patent/ES2105524T3/es not_active Expired - Lifetime
- 1994-06-01 BR BR9402150A patent/BR9402150A/pt not_active Application Discontinuation
- 1994-06-01 TW TW083105007A patent/TW449596B/zh not_active IP Right Cessation
- 1994-06-01 CZ CZ941341A patent/CZ284225B6/cs not_active IP Right Cessation
- 1994-06-01 NZ NZ260652A patent/NZ260652A/en unknown
- 1994-06-01 DE DE69404560T patent/DE69404560T2/de not_active Expired - Fee Related
- 1994-06-01 PE PE1994243645A patent/PE13295A1/es not_active Application Discontinuation
- 1994-06-02 UA UA94005240A patent/UA34440C2/uk unknown
- 1994-06-02 MY MYPI94001409A patent/MY110725A/en unknown
- 1994-06-02 PH PH48387A patent/PH30184A/en unknown
- 1994-06-02 IL IL109870A patent/IL109870A/en not_active IP Right Cessation
- 1994-06-02 CA CA002125000A patent/CA2125000A1/fr not_active Abandoned
- 1994-06-02 CO CO94023736A patent/CO4230099A1/es unknown
- 1994-06-02 AU AU64517/94A patent/AU682503B2/en not_active Ceased
- 1994-06-02 NO NO942049A patent/NO307052B1/no not_active IP Right Cessation
- 1994-06-02 KR KR1019940012341A patent/KR950000702A/ko not_active Abandoned
- 1994-06-03 HU HU9401674A patent/HU217067B/hu not_active IP Right Cessation
- 1994-06-03 YU YU33494A patent/YU33494A/sh unknown
- 1994-06-03 JP JP6122282A patent/JPH06345761A/ja active Pending
- 1994-06-03 CN CN94106983A patent/CN1045296C/zh not_active Expired - Fee Related
- 1994-06-03 FI FI942632A patent/FI942632A7/fi unknown
- 1994-06-03 RU RU94019423A patent/RU2130456C1/ru active
1997
- 1997-10-09 GR GR970402632T patent/GR3024989T3/el unknown

Also Published As

Publication number	Publication date
IL109870A (en)	1998-06-15
NO307052B1 (no)	2000-01-31
TW449596B (en)	2001-08-11
RU94019423A (ru)	1996-04-20
GR3024989T3 (en)	1998-01-30
JPH06345761A (ja)	1994-12-20
US5352782A (en)	1994-10-04
FI942632L (fi)	1994-12-05
PL174535B1 (pl)	1998-08-31
DE69404560D1 (de)	1997-09-04
ES2105524T3 (es)	1997-10-16
HU9401674D0 (en)	1994-09-28
NO942049L (no)	1994-12-05
DE69404560T2 (de)	1997-12-18
HU217067B (hu)	1999-11-29
PL303677A1 (en)	1995-01-09
PE13295A1 (es)	1995-05-24
CZ134194A3 (en)	1994-12-15
FI942632A0 (fi)	1994-06-03
CN1045296C (zh)	1999-09-29
CN1097755A (zh)	1995-01-25
CO4230099A1 (es)	1995-10-19
CA2125000A1 (fr)	1994-12-05
IL109870A0 (en)	1994-10-07
MY110725A (en)	1999-01-30
HUT67975A (en)	1995-05-29
CZ284225B6 (cs)	1998-09-16
NO942049D0 (no)	1994-06-02
BR9402150A (pt)	1994-12-27
ZA943826B (en)	1995-12-01
KR950000702A (ko)	1995-01-03
UA34440C2 (uk)	2001-03-15
RU2130456C1 (ru)	1999-05-20
PH30184A (en)	1997-01-21
EP0627431A1 (fr)	1994-12-07
EP0627431B1 (fr)	1997-07-30
YU33494A (sh)	1996-10-18
NZ260652A (en)	1995-09-26
ATE156129T1 (de)	1997-08-15
AU682503B2 (en)	1997-10-09
FI942632A7 (fi)	1994-12-05
AU6451794A (en)	1994-12-08

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