DK0632017T3 - Nye N-phenyl-2-cyano-3-hydroxy-propenamider, deres tautomere former og deres salte, fremgangsmåde til deres fremstilling, d - Google Patents
Nye N-phenyl-2-cyano-3-hydroxy-propenamider, deres tautomere former og deres salte, fremgangsmåde til deres fremstilling, dInfo
- Publication number
- DK0632017T3 DK0632017T3 DK94401458T DK94401458T DK0632017T3 DK 0632017 T3 DK0632017 T3 DK 0632017T3 DK 94401458 T DK94401458 T DK 94401458T DK 94401458 T DK94401458 T DK 94401458T DK 0632017 T3 DK0632017 T3 DK 0632017T3
- Authority
- DK
- Denmark
- Prior art keywords
- salts
- preparation
- alkyl
- tautomeric forms
- propenamides
- Prior art date
Links
- 150000003839 salts Chemical class 0.000 title abstract 2
- JDWITBSPTPZVEX-UHFFFAOYSA-N 2-cyano-3-hydroxy-n-phenylprop-2-enamide Chemical class OC=C(C#N)C(=O)NC1=CC=CC=C1 JDWITBSPTPZVEX-UHFFFAOYSA-N 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 6
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 3
- 229910052736 halogen Inorganic materials 0.000 abstract 3
- 150000002367 halogens Chemical class 0.000 abstract 2
- JCXJVPUVTGWSNB-UHFFFAOYSA-N Nitrogen dioxide Chemical compound O=[N]=O JCXJVPUVTGWSNB-UHFFFAOYSA-N 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
- C07C255/19—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and carboxyl groups, other than cyano groups, bound to the same saturated acyclic carbon skeleton
- C07C255/20—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and carboxyl groups, other than cyano groups, bound to the same saturated acyclic carbon skeleton the carbon skeleton being further substituted by singly-bound oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pain & Pain Management (AREA)
- Pharmacology & Pharmacy (AREA)
- Rheumatology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB939313365A GB9313365D0 (en) | 1993-06-29 | 1993-06-29 | Chemical compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0632017T3 true DK0632017T3 (da) | 1999-03-15 |
Family
ID=10737965
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK94401458T DK0632017T3 (da) | 1993-06-29 | 1994-06-28 | Nye N-phenyl-2-cyano-3-hydroxy-propenamider, deres tautomere former og deres salte, fremgangsmåde til deres fremstilling, d |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5416112A (de) |
| EP (1) | EP0632017B1 (de) |
| JP (1) | JP3705614B2 (de) |
| AT (1) | ATE165815T1 (de) |
| CA (1) | CA2126917C (de) |
| DE (1) | DE69410021T2 (de) |
| DK (1) | DK0632017T3 (de) |
| ES (1) | ES2115893T3 (de) |
| GB (1) | GB9313365D0 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9520092D0 (en) * | 1995-10-02 | 1995-12-06 | Hoechst Roussel Ltd | Chemical compounds |
| US6011051A (en) * | 1996-07-31 | 2000-01-04 | Hoechst Aktiengesellschaft | Use of isoxazole and crotonamide derivatives for the modulation of apoptosis |
| MXPA04000695A (es) * | 2001-07-23 | 2005-08-26 | Galileo Pharmaceuticals Inc | Compuestos citoprotectores, formulaciones farmaceuticas y cosmeticas y metodos. |
| SI1511718T1 (sl) * | 2002-05-29 | 2009-08-31 | Hoffmann La Roche | Derivati n-acilaminobenzena kot selektivni inhibitorji monoaminske oksidaze b |
| ATE411027T1 (de) * | 2003-10-23 | 2008-10-15 | Hoffmann La Roche | Benzazepin-derivate als mao-b-hemmer |
| KR20160079123A (ko) | 2013-11-22 | 2016-07-05 | 젠자임 코포레이션 | 신경변성 질병을 치료하기 위한 신규한 방법 |
| CN115322120B (zh) * | 2021-05-11 | 2024-04-30 | 四川大学 | 一类小分子化合物及在制备治疗dhodh介导疾病药物中的用途 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR551230A (fr) * | 1922-05-10 | 1923-03-30 | Moreaux Fils & Boyer | Fixation des boutons ou béquilles doubles sur les carrés des serrures |
| NL186239B (nl) * | 1975-06-05 | Hoechst Ag | Werkwijze voor de bereiding van een geneesmiddel met antiflogistische en/of analgetische werking, alsmede werkwijze voor de bereiding van een 2-hydroxyethylideencyaanazijnzuuranilide geschikt voor toepassing bij deze werkwijze. | |
| ES2102367T3 (es) * | 1990-05-18 | 1997-08-01 | Hoechst Ag | Amidas de acidos isoxazol-4-carboxilicos y amidas de acidos hidroxialquiliden-cianoaceticos, medicamentos que contienen estos compuestos y su utilizacion. |
| IL99811A (en) * | 1990-10-30 | 1996-03-31 | Roussel Uclaf | 3-cycloalkyl-propanamides their tautomer forms and their salts preparation process and compositions containing them |
| IL102790A (en) * | 1991-09-17 | 1996-01-31 | Roussel Uclaf | 3-Cycloalkyl-prop-2- enamide derivatives |
| GB9200275D0 (en) * | 1992-01-08 | 1992-02-26 | Roussel Lab Ltd | Chemical compounds |
-
1993
- 1993-06-29 GB GB939313365A patent/GB9313365D0/en active Pending
-
1994
- 1994-06-06 US US08/254,162 patent/US5416112A/en not_active Expired - Lifetime
- 1994-06-28 AT AT94401458T patent/ATE165815T1/de active
- 1994-06-28 EP EP94401458A patent/EP0632017B1/de not_active Expired - Lifetime
- 1994-06-28 CA CA002126917A patent/CA2126917C/fr not_active Expired - Lifetime
- 1994-06-28 DE DE69410021T patent/DE69410021T2/de not_active Expired - Lifetime
- 1994-06-28 JP JP16752394A patent/JP3705614B2/ja not_active Expired - Lifetime
- 1994-06-28 DK DK94401458T patent/DK0632017T3/da active
- 1994-06-28 ES ES94401458T patent/ES2115893T3/es not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP0632017B1 (de) | 1998-05-06 |
| DE69410021D1 (de) | 1998-06-10 |
| ES2115893T3 (es) | 1998-07-01 |
| ATE165815T1 (de) | 1998-05-15 |
| CA2126917C (fr) | 2007-01-30 |
| CA2126917A1 (fr) | 1994-12-30 |
| EP0632017A1 (de) | 1995-01-04 |
| US5416112A (en) | 1995-05-16 |
| GB9313365D0 (en) | 1993-08-11 |
| DE69410021T2 (de) | 1999-02-11 |
| JP3705614B2 (ja) | 2005-10-12 |
| JPH0717936A (ja) | 1995-01-20 |
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