DK0633721T3 - Rensning af blodplader med 8-metoxypsoralen - Google Patents

Rensning af blodplader med 8-metoxypsoralen

Info

Publication number
DK0633721T3
DK0633721T3 DK93907082T DK93907082T DK0633721T3 DK 0633721 T3 DK0633721 T3 DK 0633721T3 DK 93907082 T DK93907082 T DK 93907082T DK 93907082 T DK93907082 T DK 93907082T DK 0633721 T3 DK0633721 T3 DK 0633721T3
Authority
DK
Denmark
Prior art keywords
methoxypsoralen
blood
contaminants
platelet purification
platelet
Prior art date
Application number
DK93907082T
Other languages
English (en)
Inventor
Lily Lin
Laurence Corash
Stephen T Isaacs
Carl V Hanson
George D Cimino
Original Assignee
Cerus Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cerus Corp filed Critical Cerus Corp
Application granted granted Critical
Publication of DK0633721T3 publication Critical patent/DK0633721T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10Preservation of living parts
    • A01N1/12Chemical aspects of preservation
    • A01N1/122Preservation or perfusion media
    • A01N1/124Disinfecting agents, e.g. antimicrobials
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10Preservation of living parts
    • A01N1/14Mechanical aspects of preservation; Apparatus or containers therefor
    • A01N1/142Apparatus
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10Preservation of living parts
    • A01N1/16Physical preservation processes
    • A01N1/168Physical preservation processes using electromagnetic fields or radiation; using acoustic waves or corpuscular radiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365Lactones
    • A61K31/366Lactones having six-membered rings, e.g. delta-lactones
    • A61K31/37Coumarins, e.g. psoralen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/10Inactivation or decontamination of a medicinal preparation prior to administration to an animal or a person
    • A61K41/17Inactivation or decontamination of a medicinal preparation prior to administration to an animal or a person by ultraviolet [UV] or infrared [IR] light, X-rays or gamma rays
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/02Disinfection or sterilisation of materials or objects, in general; Accessories therefor using physical processes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/16Disinfection or sterilisation of materials or objects, in general; Accessories therefor using chemical substances
    • A61L2/18Liquid substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3616Batch-type treatment
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3681Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation
    • A61M1/3683Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation using photoactive agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3681Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation
    • A61M1/3683Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation using photoactive agents
    • A61M1/3686Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation using photoactive agents by removing photoactive agents after irradiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2103/00Materials or objects being the target of disinfection or sterilisation
    • A61L2103/05Living organisms or biological materials

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Wood Science & Technology (AREA)
  • Environmental Sciences (AREA)
  • Zoology (AREA)
  • Dentistry (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DK93907082T 1992-03-02 1993-02-26 Rensning af blodplader med 8-metoxypsoralen DK0633721T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/844,790 US5288605A (en) 1992-03-02 1992-03-02 Methods for inactivating bacteria in blood preparations with 8-methoxypsoralen
PCT/US1993/001786 WO1993017553A1 (en) 1992-03-02 1993-02-26 Decontaminating blood components with 8-methoxypsoralen

Publications (1)

Publication Number Publication Date
DK0633721T3 true DK0633721T3 (da) 2000-10-09

Family

ID=25293640

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93907082T DK0633721T3 (da) 1992-03-02 1993-02-26 Rensning af blodplader med 8-metoxypsoralen

Country Status (12)

Country Link
US (1) US5288605A (da)
EP (1) EP0633721B1 (da)
JP (1) JP3502095B2 (da)
AT (1) ATE193418T1 (da)
AU (1) AU663939B2 (da)
CA (1) CA2131168C (da)
DE (1) DE69328777T2 (da)
DK (1) DK0633721T3 (da)
ES (1) ES2147752T3 (da)
GR (1) GR3034069T3 (da)
PT (1) PT633721E (da)
WO (1) WO1993017553A1 (da)

Families Citing this family (72)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5418130A (en) 1990-04-16 1995-05-23 Cryopharm Corporation Method of inactivation of viral and bacterial blood contaminants
US5372929A (en) * 1992-01-27 1994-12-13 Cimino; George D. Methods for measuring the inactivation of pathogens
US5709991A (en) * 1992-03-02 1998-01-20 Cerus Corporation Proralen inactivation of microorganisms and psoralen removal
US6433343B1 (en) 1992-03-02 2002-08-13 Cerus Corporation Device and method for photoactivation
US5618662A (en) * 1992-03-02 1997-04-08 Cerus Corporation Intravenous administration of psoralen
US5459030A (en) * 1992-03-02 1995-10-17 Steritech, Inc. Synthetic media compositions for inactivating bacteria and viruses in blood preparations with 8-methoxypsoralen
WO1996014740A1 (en) 1992-03-02 1996-05-23 Cerus Corporation Synthetic media for blood components
SE9201413L (sv) * 1992-04-30 1993-10-31 Stiftelsen Foer Medicinsk Tekn Beredning och sätt för aferesframställning av trombocytkoncentrat med väsentligt förlängd hållbarhet
ES2147203T3 (es) * 1992-08-07 2000-09-01 Cerus Corp Procedimientos de inactivacion de bacterias en las preparaciones a base de sangre con la ayuda de 8-metoxipsoraleno.
US5399719A (en) * 1993-06-28 1995-03-21 Steritech, Inc. Compounds for the photodecontamination of pathogens in blood
US6420570B1 (en) 1993-06-28 2002-07-16 Cerus Corporation Psoralen compounds
US5625079A (en) 1993-06-28 1997-04-29 Cerus Corporation Synthesizing psoralen compounds useful as intermediates
JP3677287B2 (ja) * 1993-11-10 2005-07-27 セラス コーポレーション 光活性化のための装置および方法
FR2712493B1 (fr) * 1993-11-16 1996-01-19 Centre Nat Rech Scient Utilisation de photosensibilisateurs dérivés du noyau phorbine pour la décontamination du sang infecté par des parasites et/ou des virus.
US5660731A (en) * 1994-11-08 1997-08-26 Pall Corporation Filter for separating photoactive agent
US5663043A (en) * 1995-01-04 1997-09-02 Hemasure Inc. Method for inactivating non-enveloped viruses using a viricide-potentiating agent with a photoactivatible virucide
US5658271A (en) * 1996-02-08 1997-08-19 Loubser; Paul G. Closed circuit autologous sequestration reservoir system
CA2250919C (en) * 1996-03-29 2008-05-13 Therakos, Inc. Photopheresis treatment of leukocytes
ES2251020T3 (es) * 1996-03-29 2006-04-16 Therakos, Inc. Tratamiento por fotoferesis de infecciones por hcv cronicas.
AU714882B2 (en) 1996-04-09 2000-01-13 Therakos, Inc. Method for removal of psoralens from biological fluids
US20020115585A1 (en) * 1996-06-07 2002-08-22 Hei Derek J. Method and devices for the removal of psoralens from blood products
US5922278A (en) 1996-11-19 1999-07-13 Baxter International Inc. Method and apparatus for inactivating contaminants in biological fluid
US20010018179A1 (en) 1998-01-06 2001-08-30 Derek J. Hei Batch devices for the reduction of compounds from biological compositions containing cells and methods of use
US20010009756A1 (en) 1998-01-06 2001-07-26 Derek Hei Flow devices for the reduction of compounds from biological compositions and methods of use
DK0994743T3 (da) * 1997-07-10 2006-10-02 Therakos Inc Behandling af inflammatoriske lidelser i tarm eller urinblære
EP1032265B1 (en) * 1997-11-20 2003-10-29 Cerus Corporation New psoralens for pathogen inactivation
US7611831B2 (en) * 1998-01-06 2009-11-03 Cerus Corporation Adsorbing pathogen-inactivating compounds with porous particles immobilized in a matrix
US7498156B2 (en) * 1998-07-21 2009-03-03 Caridianbct Biotechnologies, Llc Use of visible light at wavelengths of 500 to 550 nm to reduce the number of pathogens in blood and blood components
US6258577B1 (en) 1998-07-21 2001-07-10 Gambro, Inc. Method and apparatus for inactivation of biological contaminants using endogenous alloxazine or isoalloxazine photosensitizers
US20070099170A1 (en) * 1998-07-21 2007-05-03 Navigant Biotechnologies, Inc. Method for treatment and storage of blood and blood products using endogenous alloxazines and acetate
US7049110B2 (en) * 1998-07-21 2006-05-23 Gambro, Inc. Inactivation of West Nile virus and malaria using photosensitizers
US20030215784A1 (en) * 1998-07-21 2003-11-20 Dumont Larry Joe Method and apparatus for inactivation of biological contaminants using photosensitizers
US6193681B1 (en) * 1998-09-14 2001-02-27 American Immuno Tech, Llc. Septicemia prevention and treatment system
US6565802B1 (en) 1999-06-03 2003-05-20 Baxter International Inc. Apparatus, systems and methods for processing and treating a biological fluid with light
US7068361B2 (en) 1999-06-03 2006-06-27 Baxter International Apparatus, systems and methods for processing and treating a biological fluid with light
US6219584B1 (en) 1999-07-09 2001-04-17 Therakos, Inc. Method and system for determining an effective amount of light energy to delivery to fluids having targets for the light energy
US7220747B2 (en) 1999-07-20 2007-05-22 Gambro, Inc. Method for preventing damage to or rejuvenating a cellular blood component using mitochondrial enhancer
US7094378B1 (en) 2000-06-15 2006-08-22 Gambro, Inc. Method and apparatus for inactivation of biological contaminants using photosensitizers
US6495366B1 (en) * 1999-09-03 2002-12-17 Therakos, Inc. Uninterrupted flow pump apparatus and method
US8722422B2 (en) 1999-09-03 2014-05-13 Therakos, Inc. Uninterrupted flow pump apparatus and method
US6268120B1 (en) 1999-10-19 2001-07-31 Gambro, Inc. Isoalloxazine derivatives to neutralize biological contaminants
US6793643B1 (en) 2000-04-21 2004-09-21 Therakos, Inc. Low extracorporeal volume treatment system
TW590780B (en) * 2000-06-02 2004-06-11 Gambro Inc Additive solutions containing riboflavin
US7985588B2 (en) * 2000-06-02 2011-07-26 Caridianbct Biotechnologies, Llc Induction of and maintenance of nucleic acid damage in pathogens using riboflavin and light
US7648699B2 (en) * 2000-06-02 2010-01-19 Caridianbct Biotechnologies, Llc Preventing transfusion related complications in a recipient of a blood transfusion
US6843961B2 (en) * 2000-06-15 2005-01-18 Gambro, Inc. Reduction of contaminants in blood and blood products using photosensitizers and peak wavelengths of light
US9044523B2 (en) 2000-06-15 2015-06-02 Terumo Bct, Inc. Reduction of contaminants in blood and blood products using photosensitizers and peak wavelengths of light
US6548241B1 (en) * 2000-11-28 2003-04-15 Gambro, Inc. Storage solution containing photosensitizer for inactivation of biological contaminants
US20030141260A1 (en) * 2001-12-28 2003-07-31 Frank Corbin Oxygen-enhanced pathogen inactivation
US20080299538A1 (en) * 2003-02-28 2008-12-04 Caridianbct Biotechnologies, Llc Pathogen Inactivation of Whole Blood
US7207964B2 (en) * 2003-03-17 2007-04-24 Hemavation, Llc Apparatus and method for down-regulating immune system mediators in blood
US20040182783A1 (en) * 2003-03-17 2004-09-23 Walker Kimberly A. Filter and concentrator device for treatment of blood
US7201730B2 (en) * 2003-03-17 2007-04-10 Hemavation, Llc Device and method for reducing inflammatory mediators in blood
US20040185426A1 (en) * 2003-03-17 2004-09-23 Mallett Scott R. Ultraviolet light and filter apparatus for treatment of blood
US20040185041A1 (en) * 2003-03-17 2004-09-23 Henna Vation, Llc Method for extracorporeal treatment of blood
US7229427B2 (en) * 2003-03-17 2007-06-12 Hemavation Irradiation and filter device for treatment of blood
US20040186407A1 (en) * 2003-03-17 2004-09-23 Kimberly Walker Concentrator and filter apparatus for treatment of blood
US20040186412A1 (en) * 2003-03-17 2004-09-23 Mallett Scott R. Extracorporeal blood treatment system using ultraviolet light and filters
US20070009377A1 (en) * 2005-07-06 2007-01-11 Navigant Biotechnologies, Inc. Methods for Reducing Pathogens in Biological Samples
WO2009026073A1 (en) * 2007-08-22 2009-02-26 Caridianbct Biotechnologies, Llc Prevention of transfusion related acute lung injury using riboflavin and light
US8968992B2 (en) * 2008-03-21 2015-03-03 Fenwal, Inc. Red blood cell storage medium for extended storage
US8871434B2 (en) * 2008-03-21 2014-10-28 Fenwal, Inc. Red blood cell storage medium for extended storage
US11864553B2 (en) 2009-10-23 2024-01-09 Fenwal, Inc. Methods and systems for providing red blood cell products with reduced plasma
SG10202004071UA (en) 2015-06-26 2020-05-28 Cerus Corp Cryoprecipitate compositions and methods of preparation thereof
EP3364986B1 (en) 2015-10-23 2023-12-13 Cerus Corporation Pathogen-inactivated cryo-poor plasma and methods of use thereof
US20190369087A1 (en) 2016-12-23 2019-12-05 Cerus Corporation Systems and methods for testing and screening using compound bound substrates
US11235090B2 (en) 2017-03-03 2022-02-01 Cerus Corporation Kits and methods for preparing pathogen-inactivated platelet compositions
CN116571191A (zh) * 2017-12-29 2023-08-11 塞鲁斯公司 用于处理生物流体的系统和方法
JP7576052B2 (ja) 2019-06-22 2024-10-30 シーラス コーポレイション 生物学的流体処理システム
US12514944B2 (en) 2019-06-22 2026-01-06 Cerus Corporation Systems and methods for implementing treatment of biological fluids
KR20220039716A (ko) 2019-06-28 2022-03-29 세루스 코포레이션 생물학적 유체 처리 장치를 구현하기 위한 시스템 및 방법
DE102020131487A1 (de) * 2020-11-27 2022-06-02 Lippert Gmbh & Co. Kg Vorrichtung zur Desinfektion von Paketen oder Stückgut

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4169204A (en) * 1976-10-20 1979-09-25 Regents Of The University Of California Psoralens
US4196281A (en) * 1976-10-20 1980-04-01 Regents Of The University Of California Psoralens
US4124598A (en) * 1976-10-20 1978-11-07 Hoffmann-La Roche Inc. Psoralens
US4321919A (en) * 1979-12-11 1982-03-30 Leukocyte Research, Inc. Method and system for externally treating human blood
US4748120A (en) * 1983-05-02 1988-05-31 Diamond Scientific Co. Photochemical decontamination treatment of whole blood or blood components
US4727027A (en) * 1983-05-02 1988-02-23 Diamond Scientific Co. Photochemical decontamination treatment of whole blood or blood components
ATE59145T1 (de) * 1983-05-02 1991-01-15 Diamond Scient Co Photochemische entkeimungsbehandlung von vollem blut oder blutbestandteilen.
DK507185A (da) * 1984-11-05 1986-05-06 Du Pont Fremgangsmaade til inaktivering af human tumor leukaemi virus iii
US4944920A (en) * 1986-08-01 1990-07-31 University Of Southern California Novel method to treat blood
US4878891A (en) * 1987-06-25 1989-11-07 Baylor Research Foundation Method for eradicating infectious biological contaminants in body tissues
DE3805459A1 (de) * 1988-02-22 1989-08-31 Biotest Pharma Gmbh Verfahren zur sterilisation von blut, plasma, blut- und plasmaderivaten, zellsuspensionen oder dgl.
US4960408A (en) * 1989-01-10 1990-10-02 Klainer Albert S Treatment methods and vaccines for stimulating an immunological response against retroviruses
US4997577A (en) * 1989-12-20 1991-03-05 Baxter International Inc. Systems and methods for removing undesired matter from blood cells

Also Published As

Publication number Publication date
EP0633721B1 (en) 2000-05-31
US5288605A (en) 1994-02-22
EP0633721A4 (en) 1996-07-03
JPH08501058A (ja) 1996-02-06
DE69328777D1 (de) 2000-07-06
AU3781093A (en) 1993-10-05
WO1993017553A1 (en) 1993-09-16
PT633721E (pt) 2000-10-31
ES2147752T3 (es) 2000-10-01
AU663939B2 (en) 1995-10-26
GR3034069T3 (en) 2000-11-30
CA2131168A1 (en) 1993-09-16
JP3502095B2 (ja) 2004-03-02
EP0633721A1 (en) 1995-01-18
ATE193418T1 (de) 2000-06-15
DE69328777T2 (de) 2000-11-30
CA2131168C (en) 2003-05-27

Similar Documents

Publication Publication Date Title
DK0633721T3 (da) Rensning af blodplader med 8-metoxypsoralen
DK0653911T3 (da) Fremgangsmåder til inaktivering af bakterier i blodpræparater med 8-methoxypsoralen
ATE242960T1 (de) Vorrichtung und verfahren zur photoaktivierung
DK0975214T3 (da) Forbedret opbevaring og opretholdelse af blodprodukter
FI920664A7 (fi) Menetelmä hammas- ja sairaanhoidon alalla käytettävien restauraatioide n, proteesien tai vastaavien valmistamiseksi
FI946004A0 (fi) Lääketieteellisessä toimenpiteessä käytettävä trombiiniverifraktio
ES2130428T3 (es) Cristales de insulina asp-b28.
BR9707049A (pt) Agentes anticoagulantes utilizáveis no tratamento de trombose
DK1187530T3 (da) Forbedret opbevaring og holdbarhed af blodprodukter
DK0383417T3 (da) Flagmusespyt-plasminogenaktivator v-PAalfa1
NO931342D0 (no) Benzimidazoler, medisinske preparater inneholdende disse,og fremgangsmaate for deres fremstilling
FI883005A7 (fi) Promoottoreita vieras-DNA:n ilmaisemiseksi metylotrofisissa bakteereissa, niiden talteenotto ja niiden käyttö.
DK147088D0 (da) Middel til behandling af virale infektioner i mennesker
FI880636A7 (fi) Menetelmä vaipallisten virusten inaktivoimiseksi solun avulla in vitro valmistetuissa proteiinivalmisteissa.
DK35588D0 (da) Hoejniveau-ekspression i e. coli af oploeseligt, modent humant interleukin-1beta og derivater med aendret biologisk virkning
IT1245625B (it) Bottiglia per dialisi renale, in particolare per la pulitura e la disinfezione di emodializzatori
FI971879L (fi) Allogeenisten ja ksenogeenisten proteiinien vasta-aineet, niiden käyttö diagnoosissa ja hoidossa ja menetelmät niiden määrittämiseksi
ES2057528T3 (es) Pdgf-a, pdgf-aa, pdgf-ab, procedimientos de preparacion y medicamentos que los contienen.
FI900379A7 (fi) Uudet farmaseuttiset seokset ja uudet farmaseuttiset tuotteet, jotka sallivat leukosyyttien regeneroimisen ja niiden käyttö AIDS:in hoidossa
DK0644768T3 (da) Fremgangsmåder og præparater til inhibering af endotelcelle- og fibrinogenfremkaldt inflammation
IT8740154A0 (it) Raccoglitore di aghi usati in campo medicale, in particolare di tipo epicranico e/o per dialisi
DE59405845D1 (de) Verwendung von 2-Methylamino-2-phenylcyclohexanon zur Behandlung von Infektionen und zur Immunmodulation
ITRM930551A0 (it) Procedimento per la propagazione del virus dell'epatite c in colture cellulari animali non linfoblastoidi e relativo prodotto.