DK0637583T3 - 1-Aryloxy-3-alkylamino-2-propanol-nitratestere, anvendelse heraf og tilsvarende farmaceutisk præparat - Google Patents
1-Aryloxy-3-alkylamino-2-propanol-nitratestere, anvendelse heraf og tilsvarende farmaceutisk præparatInfo
- Publication number
- DK0637583T3 DK0637583T3 DK94500111.3T DK94500111T DK0637583T3 DK 0637583 T3 DK0637583 T3 DK 0637583T3 DK 94500111 T DK94500111 T DK 94500111T DK 0637583 T3 DK0637583 T3 DK 0637583T3
- Authority
- DK
- Denmark
- Prior art keywords
- alkylamino
- aryloxy
- nitrate esters
- pharmaceutical preparation
- corresponding pharmaceutical
- Prior art date
Links
- KFZMGEQAYNKOFK-UHFFFAOYSA-N 2-propanol Substances CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 title 1
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- RTZKZFJDLAIYFH-UHFFFAOYSA-N ether Substances CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 3
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001408 amides Chemical group 0.000 abstract 1
- 230000002526 effect on cardiovascular system Effects 0.000 abstract 1
- 150000002148 esters Chemical group 0.000 abstract 1
- 125000001624 naphthyl group Chemical group 0.000 abstract 1
- 150000002823 nitrates Chemical class 0.000 abstract 1
- -1 nitroxy group Chemical group 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C07C235/34—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C217/28—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines
- C07C217/30—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring
- C07C217/32—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Heart & Thoracic Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Emergency Medicine (AREA)
- Epidemiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES09301721A ES2065291B1 (es) | 1993-07-30 | 1993-07-30 | "nitrato esteres de 1-ariloxi-3-alquilamino-2-propanoles, utilizacion y composicion farmaceutica correspondiente" |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0637583T3 true DK0637583T3 (da) | 1997-05-12 |
Family
ID=8282739
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK94500111.3T DK0637583T3 (da) | 1993-07-30 | 1994-06-23 | 1-Aryloxy-3-alkylamino-2-propanol-nitratestere, anvendelse heraf og tilsvarende farmaceutisk præparat |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US5502237A (da) |
| EP (1) | EP0637583B1 (da) |
| JP (1) | JP2777572B2 (da) |
| KR (1) | KR950003262A (da) |
| AT (1) | ATE146453T1 (da) |
| AU (1) | AU666626B2 (da) |
| CA (1) | CA2128671A1 (da) |
| CO (1) | CO4290296A1 (da) |
| DE (1) | DE69401177T2 (da) |
| DK (1) | DK0637583T3 (da) |
| ES (1) | ES2065291B1 (da) |
| GR (1) | GR3022704T3 (da) |
| HU (1) | HU214827B (da) |
| MX (1) | MX9405660A (da) |
| NO (1) | NO179746C (da) |
| NZ (1) | NZ264118A (da) |
| PL (1) | PL175707B1 (da) |
| ZA (1) | ZA945435B (da) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1295694B1 (it) * | 1996-11-14 | 1999-05-27 | Nicox Sa | Nitrossi derivati per la preparazione di medicamenti ad attivita antitrombinica |
| CN1083824C (zh) * | 1999-09-24 | 2002-05-01 | 许景峰 | 具有心血管药理活性的合成化合物及制备方法 |
| EP1670459A4 (en) * | 2003-08-20 | 2009-03-25 | Nitromed Inc | NITROSED AND NITROSYLATED CARDIOVASCULAR COMPOUNDS, COMPOSITIONS AND APPLICATION METHODS |
| EP1748994B1 (en) * | 2003-12-02 | 2009-02-18 | NicOx S.A. | Nitrooxyderivatives of antihypertensive drugs |
| AR047732A1 (es) | 2003-12-02 | 2006-02-15 | Nicox Sa | Nitrooxiderivados de drogas antihipertensivas |
| WO2006052899A2 (en) * | 2004-11-08 | 2006-05-18 | Nitromed, Inc. | Nitrosated and nitrosylated compounds, compositions and methods for the treatment of ophthalmic disorders |
| KR102240153B1 (ko) | 2017-08-01 | 2021-04-14 | 강흥섭 | 복층유리제조용 듀얼 프레싱장치 |
| KR102324664B1 (ko) | 2017-08-01 | 2021-11-10 | 주식회사 이강테크 | 듀얼 프레스를 이용한 복층유리 제조장치 |
| KR102240154B1 (ko) | 2017-09-08 | 2021-04-14 | 강흥섭 | 유리판 다중 공급장치 |
| KR200494614Y1 (ko) | 2017-09-08 | 2021-11-17 | 주식회사 이강테크 | 복층 유리 제조에 적용되는 유리판 검사장치 |
| KR20210020341A (ko) | 2019-08-14 | 2021-02-24 | 주식회사 아이지스 | 복층 유리 제조를 위한 컨베어용 자동 분배 공급장치 |
| KR102163495B1 (ko) | 2019-08-22 | 2020-10-07 | 주식회사 아이지스 | 복층유리의 가스 주입을 갖는 더블 프레스 장치 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE354851B (da) * | 1970-02-18 | 1973-03-26 | Haessle Ab | |
| DE2839475A1 (de) * | 1978-09-11 | 1980-03-20 | Dolorgiet Arzneimittelfabrik | Isopropylamin-verbindungen, verfahren zu ihrer herstellung und sie enthaltende arzneimittel |
| JPS56113748A (en) * | 1980-02-13 | 1981-09-07 | Kowa Co | Aminoethanol derivative and its preparation |
| US4387103A (en) * | 1980-11-28 | 1983-06-07 | American Hospital Supply Corporation | Method for treatment or prophylaxis of cardiac disorders |
| JPS58109461A (ja) * | 1981-12-24 | 1983-06-29 | Kowa Co | 新規ベンズアミド誘導体 |
| DE3443998A1 (de) * | 1984-12-01 | 1986-06-05 | Boehringer Mannheim Gmbh, 6800 Mannheim | Amino-propanol-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel sowie zwischenprodukte |
| NL8802276A (nl) * | 1988-09-15 | 1990-04-02 | Cedona Pharm Bv | Geneesmiddel met relaxerende werking, dat als aktieve stof een nitraatester bevat. |
| IT1243367B (it) * | 1990-07-26 | 1994-06-10 | Italfarmaco Spa | Derivati acidi benzoici sostituiti ad attivita' cardiovascolare |
| ES2026756A6 (es) * | 1990-09-24 | 1992-05-01 | Prodesfarma Sa | Procedimiento para la obtencion de nitratos de 1-ariloxi-3 amino-2-propilo. |
-
1993
- 1993-07-30 ES ES09301721A patent/ES2065291B1/es not_active Expired - Lifetime
-
1994
- 1994-06-23 AT AT94500111T patent/ATE146453T1/de not_active IP Right Cessation
- 1994-06-23 DK DK94500111.3T patent/DK0637583T3/da active
- 1994-06-23 EP EP94500111A patent/EP0637583B1/en not_active Expired - Lifetime
- 1994-06-23 DE DE69401177T patent/DE69401177T2/de not_active Expired - Fee Related
- 1994-06-27 US US08/265,960 patent/US5502237A/en not_active Expired - Fee Related
- 1994-07-07 NO NO942568A patent/NO179746C/no unknown
- 1994-07-14 AU AU67437/94A patent/AU666626B2/en not_active Ceased
- 1994-07-18 CO CO94031366A patent/CO4290296A1/es unknown
- 1994-07-22 PL PL94304406A patent/PL175707B1/pl unknown
- 1994-07-22 CA CA002128671A patent/CA2128671A1/en not_active Abandoned
- 1994-07-22 ZA ZA945435A patent/ZA945435B/xx unknown
- 1994-07-25 MX MX9405660A patent/MX9405660A/es not_active IP Right Cessation
- 1994-07-27 JP JP6175400A patent/JP2777572B2/ja not_active Expired - Lifetime
- 1994-07-28 NZ NZ264118A patent/NZ264118A/en unknown
- 1994-07-29 HU HU9402229A patent/HU214827B/hu not_active IP Right Cessation
- 1994-07-29 KR KR1019940018560A patent/KR950003262A/ko not_active Ceased
-
1995
- 1995-08-11 US US08/514,267 patent/US5639904A/en not_active Expired - Fee Related
-
1997
- 1997-02-28 GR GR970400393T patent/GR3022704T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ATE146453T1 (de) | 1997-01-15 |
| US5502237A (en) | 1996-03-26 |
| DE69401177D1 (de) | 1997-01-30 |
| JPH0789910A (ja) | 1995-04-04 |
| NO179746B (no) | 1996-09-02 |
| AU666626B2 (en) | 1996-02-15 |
| NO942568L (no) | 1995-01-31 |
| ES2065291B1 (es) | 1995-10-01 |
| PL175707B1 (pl) | 1999-01-29 |
| HU214827B (hu) | 1998-06-29 |
| PL304406A1 (en) | 1995-02-06 |
| NO179746C (no) | 1996-12-11 |
| NO942568D0 (no) | 1994-07-07 |
| NZ264118A (en) | 1995-04-27 |
| MX9405660A (es) | 1995-01-31 |
| DE69401177T2 (de) | 1997-04-24 |
| AU6743794A (en) | 1995-02-09 |
| CO4290296A1 (es) | 1996-04-17 |
| JP2777572B2 (ja) | 1998-07-16 |
| EP0637583B1 (en) | 1996-12-18 |
| GR3022704T3 (en) | 1997-05-31 |
| ZA945435B (en) | 1995-05-11 |
| EP0637583A1 (en) | 1995-02-08 |
| HU9402229D0 (en) | 1994-09-28 |
| ES2065291A1 (es) | 1995-02-01 |
| HUT71813A (en) | 1996-02-28 |
| KR950003262A (ko) | 1995-02-16 |
| CA2128671A1 (en) | 1995-01-31 |
| US5639904A (en) | 1997-06-17 |
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