DK0639225T3 - Nye polypeptider og peptider, nucleinsyrer, der koder for dem, og deres anvendelse i området tumorterapi, inflammation eller immunologi - Google Patents

Nye polypeptider og peptider, nucleinsyrer, der koder for dem, og deres anvendelse i området tumorterapi, inflammation eller immunologi

Info

Publication number: DK0639225T3
Authority: DK; Denmark
Prior art keywords: amino acid; acid sequence; polypeptides; immunology; inflammation
Prior art date: 1992-04-30

Application number

DK93909852T

Other languages

English (en)

Inventor

De Voorde Andre Van

Heuverswyn Hugo Van

Lucia Fransen

Kathleen Devos

Original Assignee

Innogenetics Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-04-30

Filing date

1993-04-28

Publication date

2003-02-17

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8211656&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0639225(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1993-04-28 Application filed by Innogenetics Nv filed Critical Innogenetics Nv

2003-02-17 Application granted granted Critical

2003-02-17 Publication of DK0639225T3 publication Critical patent/DK0639225T3/da

Links

102000004196 processed proteins & peptides Human genes 0.000 title abstract 6
108090000765 processed proteins & peptides Proteins 0.000 title abstract 6
229920001184 polypeptide Polymers 0.000 title abstract 5
206010061218 Inflammation Diseases 0.000 title 1
206010028980 Neoplasm Diseases 0.000 title 1
230000004054 inflammatory process Effects 0.000 title 1
102000039446 nucleic acids Human genes 0.000 title 1
108020004707 nucleic acids Proteins 0.000 title 1
150000007523 nucleic acids Chemical class 0.000 title 1
238000002560 therapeutic procedure Methods 0.000 title 1
125000003275 alpha amino acid group Chemical group 0.000 abstract 4
150000001875 compounds Chemical class 0.000 abstract 3
239000012634 fragment Substances 0.000 abstract 2
210000001744 T-lymphocyte Anatomy 0.000 abstract 1
239000012190 activator Substances 0.000 abstract 1
239000013543 active substance Substances 0.000 abstract 1
150000001413 amino acids Chemical class 0.000 abstract 1
239000005557 antagonist Substances 0.000 abstract 1
230000003110 anti-inflammatory effect Effects 0.000 abstract 1
230000000259 anti-tumor effect Effects 0.000 abstract 1
210000003719 b-lymphocyte Anatomy 0.000 abstract 1
210000000988 bone and bone Anatomy 0.000 abstract 1
239000003795 chemical substances by application Substances 0.000 abstract 1
210000005008 immunosuppressive cell Anatomy 0.000 abstract 1
239000000411 inducer Substances 0.000 abstract 1
239000003112 inhibitor Substances 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
230000004936 stimulating effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/525—Tumour necrosis factor [TNF]
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
- C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/90—Fusion polypeptide containing a motif for post-translational modification
- C07K2319/91—Fusion polypeptide containing a motif for post-translational modification containing a motif for glycosylation

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Biochemistry (AREA)
Gastroenterology & Hepatology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Toxicology (AREA)
Zoology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Tropical Medicine & Parasitology (AREA)
Hematology (AREA)
Diabetes (AREA)
Immunology (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DK93909852T 1992-04-30 1993-04-28 Nye polypeptider og peptider, nucleinsyrer, der koder for dem, og deres anvendelse i området tumorterapi, inflammation eller immunologi DK0639225T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP92401231		1992-04-30
PCT/EP1993/001022 WO1993022437A1 (en)	1992-04-30	1993-04-28	New polypeptides and peptides, nucleic acids coding for them, and their use in the field of tumor therapy, inflammation or immunology

Publications (1)

Publication Number	Publication Date
DK0639225T3 true DK0639225T3 (da)	2003-02-17

Family

ID=8211656

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK93909852T DK0639225T3 (da)	1992-04-30	1993-04-28	Nye polypeptider og peptider, nucleinsyrer, der koder for dem, og deres anvendelse i området tumorterapi, inflammation eller immunologi

Country Status (9)

Country	Link
US (2)	US5981277A (da)
EP (1)	EP0639225B1 (da)
JP (1)	JPH07502171A (da)
AT (1)	ATE226250T1 (da)
DE (1)	DE69332406T2 (da)
DK (1)	DK0639225T3 (da)
ES (1)	ES2185630T3 (da)
PT (1)	PT639225E (da)
WO (1)	WO1993022437A1 (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0791061A4 (en) *	1994-03-04	1998-07-15	Ludwig Inst Cancer Res	TARGET GENE BREAKING ANIMALS
DE19846077C2 (de) *	1998-10-06	2000-09-07	Ulrich H Goeringer	Trypanosomen-bindende Nukleinsäuren, ihre Herstellung und Verwendung
EP1233779A2 (en) *	1999-11-30	2002-08-28	Innogenetics N.V.	New uses of suppressive macrophage activation factors
US7329725B1 (en) *	2003-10-29	2008-02-12	Nastech Pharmaceutical Company Inc.	Phage displayed Trp cage ligands
AU2005229434B2 (en)	2004-03-30	2010-09-30	Nsgene A/S	Therapeutic use of a growth factor, NsG33
JP4538522B2 (ja) *	2005-11-25	2010-09-08	コーリーファーマシューティカルゲーエムベーハー	免疫刺激性オリゴリボヌクレオチド
DK2195013T3 (da)	2008-07-24	2012-02-06	Nsgene As	Terapeutisk anvendelse af en vækstfaktor, METRNL
WO2012041328A1 (en)	2010-10-01	2012-04-05	Nsgene A/S	Use of meteorin for the treatment of allodynia, hyperalgesia, spontaneous pain and phantom pain
JP6145667B2 (ja)	2011-09-05	2017-06-14	ホーバセラピューティクスアンパルトセルスカブ	アロディニア、痛覚過敏、自発痛、及び幻痛の治療
US10717992B2 (en) *	2013-01-25	2020-07-21	Dana-Farber Cancer Institute, Inc.	Compositions and methods for regulating thermogenesis and muscle inflammation using metrnl and metrn
WO2015062167A1 (zh) *	2013-10-29	2015-05-07	中国人民解放军第二军医大学	Metrnl蛋白在制备降血脂降血糖药物中的应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS6490199A (en) *	1987-09-30	1989-04-06	Hiromi Fujiwara	T cell growth factor derived from thymic interstitial cell and production thereof
US5049659A (en) *	1988-02-09	1991-09-17	Dana Farber Cancer Institute	Proteins which induce immunological effector cell activation and chemattraction

1993
- 1993-04-28 DK DK93909852T patent/DK0639225T3/da active
- 1993-04-28 AT AT93909852T patent/ATE226250T1/de not_active IP Right Cessation
- 1993-04-28 PT PT93909852T patent/PT639225E/pt unknown
- 1993-04-28 JP JP5518910A patent/JPH07502171A/ja active Pending
- 1993-04-28 US US08/318,837 patent/US5981277A/en not_active Expired - Fee Related
- 1993-04-28 WO PCT/EP1993/001022 patent/WO1993022437A1/en not_active Ceased
- 1993-04-28 DE DE69332406T patent/DE69332406T2/de not_active Revoked
- 1993-04-28 ES ES93909852T patent/ES2185630T3/es not_active Expired - Lifetime
- 1993-04-28 EP EP93909852A patent/EP0639225B1/en not_active Revoked
1999
- 1999-04-19 US US09/294,121 patent/US20020069422A1/en not_active Abandoned

Also Published As

Publication number	Publication date
US20020069422A1 (en)	2002-06-06
EP0639225A1 (en)	1995-02-22
WO1993022437A1 (en)	1993-11-11
ATE226250T1 (de)	2002-11-15
EP0639225B1 (en)	2002-10-16
ES2185630T3 (es)	2003-05-01
DE69332406T2 (de)	2003-06-26
PT639225E (pt)	2003-03-31
US5981277A (en)	1999-11-09
DE69332406D1 (de)	2002-11-21
JPH07502171A (ja)	1995-03-09

Publication	Publication Date	Title
DE68929043D1 (de)	1999-09-09	Für androgen-rezeptor-protein kodierende dna
ATE168719T1 (de)	1998-08-15	Osteogene peptide
DK0639225T3 (da)	2003-02-17	Nye polypeptider og peptider, nucleinsyrer, der koder for dem, og deres anvendelse i området tumorterapi, inflammation eller immunologi
ES8203385A1 (es)	1982-04-01	Procedimiento de obtencion de nuevos derivados de la vin- blastina
ATE257485T1 (de)	2004-01-15	Varianten des vaskulären endothelzellwachsumsfaktors mit antagonistischer wirkung
BG60256B1 (bg)	1994-03-24	Рекомбинантен метод за получаване на лимфотоксин
NO952744D0 (no)	1995-07-11	Cytokinbegrensende midler
DK1037927T3 (da)	2004-09-06	Heterodimere fusionsproteiner, der er nyttige til målrettet immunterapi og generel immunstimulering
FI102379B1 (fi)	1998-11-30	Uretaanisuojattuja aminohappo-N-karboksianhydridejä
EP0149548A3 (en)	1987-05-20	Nucleic acid encoding a t-cell antigen receptor polypeptide
DE69129803D1 (de)	1998-08-20	Wasserlösliche peptidanaloguen mit bindungstellen
NZ236511A (en)	1993-02-25	Polypeptides containing sequences from residues 61 to 82 or 104 to 129 of human il-4 or subsequences thereof; antibodies and pharmaceutical compositions
ES2054365T3 (es)	1994-08-01	Inhibicion de la via de la regla del n final en celulas vivas.
ATE144535T1 (de)	1996-11-15	Plättchen blockierende peptide
DE68920931D1 (de)	1995-03-16	Rekombinanter natürlicher Killerzellen-Aktivator.
ATE309348T1 (de)	2005-11-15	Melatoninrezeptoren mit hoher affinität und ihre verwendungen
DE60039677D1 (de)	2008-09-11	Akt-3 nukleinsäure, polypeptide und deren verwendung
DE68917837D1 (de)	1994-10-06	Peptid-Verbindungen.
ATE225806T1 (de)	2002-10-15	D-2-alkyltryptophan enthaltende polypeptide mit wachstumhormon freisetzender aktivitaet
ATE287952T1 (de)	2005-02-15	Humanes thymosin beta 15 gen,protein und dessen verwendungen
ATE309351T1 (de)	2005-11-15	Einkettigen polypeptiden enthalten troponin i und troponin c
DE3650035D1 (de)	1994-09-29	THF-Zusammensetzungen.
ATE317851T1 (de)	2006-03-15	Polypeptide mit aminosäuresequenzen aus dem n- terminalen bereich von gp116 von cytomegalovirus und deren verwendung bei der diagnostik, prophylaxe und therapie
DK0555785T3 (da)	1997-05-26	Glat-muskel-mitogent stof og DNA, der koder herfor
ATE46173T1 (de)	1989-09-15	Pharmakologisch aktive peptide.