DK0645397T3 - Glutathionanalog- og -paralogpaneler, som omfatter glutathionimitatorer - Google Patents
Glutathionanalog- og -paralogpaneler, som omfatter glutathionimitatorerInfo
- Publication number
- DK0645397T3 DK0645397T3 DK93307676T DK93307676T DK0645397T3 DK 0645397 T3 DK0645397 T3 DK 0645397T3 DK 93307676 T DK93307676 T DK 93307676T DK 93307676 T DK93307676 T DK 93307676T DK 0645397 T3 DK0645397 T3 DK 0645397T3
- Authority
- DK
- Denmark
- Prior art keywords
- glutathione
- chem
- imitators
- compounds
- panels
- Prior art date
Links
- RWSXRVCMGQZWBV-WDSKDSINSA-N glutathione Chemical class OC(=O)[C@@H](N)CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O RWSXRVCMGQZWBV-WDSKDSINSA-N 0.000 title abstract 4
- 108010024636 Glutathione Proteins 0.000 title 1
- 229960003180 glutathione Drugs 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 239000003153 chemical reaction reagent Substances 0.000 abstract 2
- 102000005720 Glutathione transferase Human genes 0.000 abstract 1
- 108010070675 Glutathione transferase Proteins 0.000 abstract 1
- 150000001408 amides Chemical class 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000010828 elution Methods 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 125000001183 hydrocarbyl group Chemical group 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 239000003446 ligand Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000006467 substitution reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0215—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing natural amino acids, forming a peptide bond via their side chain functional group, e.g. epsilon-Lys, gamma-Glu
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Pharmacology & Pharmacy (AREA)
- General Engineering & Computer Science (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Detergent Compositions (AREA)
- Confectionery (AREA)
- Cosmetics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA002105492A CA2105492C (en) | 1993-09-03 | 1993-09-03 | Glutathione analogs and paralog panels comprising glutathione mimics |
| EP93307676A EP0645397B1 (en) | 1993-09-03 | 1993-09-28 | Glutathione analogs and paralog panels comprising glutathione mimics |
| AU48733/93A AU671855B2 (en) | 1993-09-03 | 1993-09-30 | Novel glutathione analogs and paralog panels comprising glutathione mimics |
| JP24723893A JP3542040B2 (ja) | 1993-09-03 | 1993-10-01 | グルタチオン模倣体を含有する新規グルタチオンアナログおよびパラログパネル |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0645397T3 true DK0645397T3 (da) | 1999-03-01 |
Family
ID=27423327
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK93307676T DK0645397T3 (da) | 1993-09-03 | 1993-09-28 | Glutathionanalog- og -paralogpaneler, som omfatter glutathionimitatorer |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0645397B1 (da) |
| JP (1) | JP3542040B2 (da) |
| AT (1) | ATE170869T1 (da) |
| AU (1) | AU671855B2 (da) |
| CA (1) | CA2105492C (da) |
| DE (1) | DE69320961T2 (da) |
| DK (1) | DK0645397T3 (da) |
| ES (1) | ES2120485T3 (da) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2794122B1 (fr) * | 1999-05-27 | 2001-09-07 | Centre Nat Rech Scient | Nouveaux antioxydants, procedes de preparation et utilisations |
| US7172905B2 (en) | 2001-08-07 | 2007-02-06 | The University Of Chicago | Polypeptide immobilization |
| EP1833978B1 (en) * | 2005-01-06 | 2008-10-08 | Telik, Inc. | Tripeptide and tetrapeptide thioethers |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61162175A (ja) * | 1985-01-11 | 1986-07-22 | Kiyomi Sato | グルタチオン−s−トランスフエラ−ゼの精製法 |
| US5133866A (en) | 1988-03-24 | 1992-07-28 | Terrapin Technologies, Inc. | Method to identify analyte-bending ligands |
| AU669847B2 (en) * | 1991-04-29 | 1996-06-27 | Telik, Inc. | Methods to profile and treat abnormal cells |
-
1993
- 1993-09-03 CA CA002105492A patent/CA2105492C/en not_active Expired - Lifetime
- 1993-09-28 DE DE69320961T patent/DE69320961T2/de not_active Expired - Lifetime
- 1993-09-28 AT AT93307676T patent/ATE170869T1/de active
- 1993-09-28 EP EP93307676A patent/EP0645397B1/en not_active Expired - Lifetime
- 1993-09-28 DK DK93307676T patent/DK0645397T3/da active
- 1993-09-28 ES ES93307676T patent/ES2120485T3/es not_active Expired - Lifetime
- 1993-09-30 AU AU48733/93A patent/AU671855B2/en not_active Ceased
- 1993-10-01 JP JP24723893A patent/JP3542040B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU671855B2 (en) | 1996-09-12 |
| JP3542040B2 (ja) | 2004-07-14 |
| DE69320961D1 (de) | 1998-10-15 |
| EP0645397B1 (en) | 1998-09-09 |
| CA2105492A1 (en) | 1995-03-04 |
| AU4873393A (en) | 1995-05-04 |
| JPH07145142A (ja) | 1995-06-06 |
| CA2105492C (en) | 2000-02-01 |
| ES2120485T3 (es) | 1998-11-01 |
| DE69320961T2 (de) | 1999-01-28 |
| EP0645397A1 (en) | 1995-03-29 |
| ATE170869T1 (de) | 1998-09-15 |
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